Amycolatopsis rhabdoformis: VSH64_07075
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Entry
VSH64_07075 CDS
T09694
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K11381
2-oxoisovalerate dehydrogenase E1 component [EC:
1.2.4.4
]
Organism
arhd
Amycolatopsis rhabdoformis
Pathway
arhd00280
Valine, leucine and isoleucine degradation
arhd00640
Propanoate metabolism
arhd00785
Lipoic acid metabolism
arhd01100
Metabolic pathways
arhd01110
Biosynthesis of secondary metabolites
arhd01210
2-Oxocarboxylic acid metabolism
Brite
KEGG Orthology (KO) [BR:
arhd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
VSH64_07075
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
VSH64_07075
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
VSH64_07075
Enzymes [BR:
arhd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
VSH64_07075
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Motif
Pfam:
E1_dh
Transket_pyr
Transketolase_C
DXP_synthase_N
Motif
Other DBs
NCBI-ProteinID:
WSE31869
UniProt:
A0ABZ1ICU7
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All DBs
Position
1522275..1524437
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AA seq
720 aa
AA seq
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MAAHESLVAGAPWIRLRATPEDWDEAEPDLLLRLLGRAQWIRSFEEYVLELAGLGLVHGP
AHSSIGQEGGAVGSISPLRSDDFVNGSHRGHHQFLAKAFGHVAGNAGGLPALDDDVRTVL
RRTLAEICGLAEGYGSGRGGSMHLQWREAGAMGTNAIVGGGVPQAAGFAWNQRRTGTDAV
TVTYFGDGAVNIGSVLETFNLAAAWRLPVCFFIENNQYAVSTPVDTATAEPRLSARGLGF
NIPSWQVDGMDPLAVHLAMSEAVAHMRAGNGPTIVEAEVYRYFHQNGPYPGSAFGYRTKE
EERSWRDRDPIDLLRAHVIRRGLADDDRLKAFDEEITRTLHEIGDSFLEDGPDGKRRIKE
SAWPDPAFVDVGVRGDLSELDGSRYEEAETFGGALDQRRFIDAVSDVLARRLETDERVVV
LGEDVDRLKGGTNGATRKAIETAPERVLGTPISENAFTGLAGGMAIDGRSRPIAEFMYAD
FMWVAADQLFNQVAKARHMFGGTGSVPFVLRSKLAAGTGYGSQHSMDPSGVLTTAPGLRV
VAPSNPFDYVGLLNTALACDDPVVVLEHVDLYASTGTAPVDDFDYRIPVGKAALRRTGDD
LTVISYLSMVGHCLEALDETGVSADLIDLRWLDRASLDWDTIETSVRKTNRVLIVEQGAI
GTSYGGRLADEIQRRLFDWLDAPIERVTGGEASPSISKVLERAAIARTEEVTAALRRLSD
NT seq
2163 nt
NT seq
+upstream
nt +downstream
nt
atggccgctcacgagtcactggtcgccggcgcgccctggatccgcctgcgcgccacgccg
gaggactgggacgaagccgaacccgacctgctgctgcgcctgctcggccgcgcgcagtgg
atccggtcgttcgaggagtacgtgctggagctcgcgggcctcggcctggtgcacgggccg
gcgcactcgagcatcggccaggagggcggcgccgtcggctcgatctcgccgctgcgcagc
gacgacttcgtgaacggctcgcaccgcggccaccaccagttcctggccaaggcattcggc
cacgtcgccgggaacgccggcggcctgcccgcgctcgacgacgacgtgcgcaccgtgctg
cgccgcacgctcgccgagatctgcggcctggccgagggctacggcagcggccgcggcggg
tcgatgcacctgcagtggcgcgaggccggcgcgatgggcaccaacgcgatcgtcggcggg
ggagtgccgcaggccgcgggcttcgcctggaaccagcgccgcaccggcaccgacgcggtg
accgtgacgtacttcggcgacggcgccgtgaacatcggctcggtgctggagacgttcaac
ctcgccgccgcgtggcggctgccggtgtgcttcttcatcgagaacaaccagtacgcggtg
tccacgccggtcgacacggccacggccgagccgcggctttccgcgcgcggtctcgggttc
aacatcccgagctggcaggtggacggaatggatccgctcgccgtgcacctggcgatgagc
gaggccgtggcgcacatgcgcgcgggcaacggcccgaccatcgtcgaggccgaggtctac
cgctacttccaccagaacgggccctaccccggcagcgccttcggctaccgcacgaaggaa
gaggaacggtcctggcgtgaccgcgacccgatcgacctcctgcgcgcccacgtgatccgc
cgcgggctcgccgacgacgaccggctcaaggcgttcgacgaggagatcacccgcacgctg
cacgaaatcggcgacagcttcctcgaggacggccccgacggcaagcgccgcatcaaggag
tccgcgtggcccgaccccgcgttcgtggacgtcggtgtgcgcggtgatctgtccgaactg
gacggcagccgctacgaggaagccgaaaccttcggcggtgctctcgatcagcgtaggttc
atcgacgcggtgagcgacgtgctcgcgcgccggctcgagaccgacgagcgcgtggtggtg
ctcggcgaggacgtcgaccggctcaagggcggcaccaacggcgccacccgcaaggccatc
gaaaccgcgcccgagcgggtgctcggcacgccgatcagcgaaaacgcgttcaccggcctc
gccggcggcatggccatcgacggccgctcgcgcccgatcgccgagttcatgtacgccgac
ttcatgtgggtcgccgccgaccagctgttcaaccaggtcgccaaggcgcggcacatgttc
ggcggcaccggcagcgtgccgttcgtgctgcgcagcaagctcgccgcgggcaccggctac
ggctcgcagcactcgatggacccgtccggcgtgctcaccaccgcgcccgggctgcgggtg
gtggcgccgtcgaacccgttcgactacgtcggcctgctgaacaccgcactggcctgcgac
gacccggtggtggtgctggaacacgtggacctctacgcgagcacgggcaccgcgccggtc
gacgacttcgactaccgcatcccggtcggcaaggccgcgttgcgccgcaccggcgacgac
ctcacggtgatcagctacctgtcgatggtgggccactgcctcgaagcgctcgacgagacc
ggcgtgagcgccgacctcatcgacctgcgctggctcgaccgcgcgagcctcgactgggac
acgatcgaaaccagcgtgcgcaagacgaaccgggtgctgatcgtggagcagggcgcgatc
ggcacgtcgtacggcggccggctcgccgacgagatccagcgccgcctcttcgactggctc
gacgcgccgatcgagcgcgtgaccggcggcgaggcgtcgcccagcatcagcaaggtcctc
gaacgcgcggcgatcgcgcggaccgaggaagtgaccgcggcgctgcggcgcctttccgac
tga
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