KEGG   Amycolatopsis rhabdoformis: VSH64_21305
Entry
VSH64_21305       CDS       T09694                                 
Name
(GenBank) SDR family NAD(P)-dependent oxidoreductase
  KO
K19208  candicidin polyketide synthase FscE
Organism
arhd  Amycolatopsis rhabdoformis
Pathway
arhd01052  Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:arhd00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    VSH64_21305
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins [BR:arhd01008]
    VSH64_21305
Polyketide biosynthesis proteins [BR:arhd01008]
 Polyketide synthase (PKS)
  Modular type I PKS
   cis-AT PKS
    Candicidin PKS
     VSH64_21305
SSDB
Motif
Pfam: ketoacyl-synt Acyl_transf_1 KR Ketoacyl-synt_C KAsynt_C_assoc PP-binding CurL-like_PKS_C Thiolase_N SpnB_Rossmann adh_short PKS_DH_N RhiE-like_linker Epimerase PS-DH ADH_zinc_N_2 ADH_zinc_N NmrA Polysacc_synt_2 GDP_Man_Dehyd ACP_SdgA_C ADH_N 3Beta_HSD ACP_syn_III SDR RmlD_sub_bind NAD_binding_4 Secretin_N
Other DBs
NCBI-ProteinID: WSE34590
UniProt: A0ABZ1IJF5
LinkDB
Position
complement(4679801..4698031)
AA seq 6076 aa
MVNSSGSGLGDGPIAIVGMACRLPKASNPREFWQLLHSGGSGVTPVPGGRWTGLAGPDAE
LLRYGGFVDDVDRFDAEFFGISPREAAVMDPQQRLALELGWEAFEDAGLVPARLRGRRVG
VFAGAMAADYELLSLRRGAIGHHSLTGLRTGMIPNRMSYAFGFTGPSLAVDTGQSSSLVA
VHLAAESIRSGESDLALAGGIQLNLAGDNAVTTARFGGLSPDGRCFTFDARANGYVRGEG
GGFVVLKPLSLALEDGDDVYAVLLGSAVNNEGPGESFTRPSAEAQEAVLRAAYRRAGVDP
GRVQYVELHGTGTKVGDPIEARALGAALGEGRTTPLSVGSAKTNVGHLESAAGIVGLVKT
ALAVRNRRLPASLNFEQPNPDIRFDEWQLRVVPSAEAWPEVEGPLLAGVSSFGVGGTNCH
VVLSSPHPAAPAREHTGMPSAESVVPVLVSGRSQAALRDQAARLADALDAEAGLAVADLA
WSSALTRSGFEHRAVVVTGDRAEASAGLRALAAGEPDPAVVTGVAAPSRGVVFVFPGQGS
QWPGMGRGLLETSPVFRQSMLECQEALAPWVSWSLIDVLTGTDGTDGAALDRVDVVQPAL
WAIMVSLSRLWRSCGVEPDAVVGHSQGEIAAACVAGALSLSDGARVVALRARALRTLAGR
GGMLSVDLSRDGVEEWLGRYPGRVSLAAVNATGSVVLAGEPEALRLLRDELTAQDIRARL
VDVDYASHSAQVDEVRAEVLEALAPIEPRPARVPFFSTVDAGWLRGTEVDAAYWFRNLRQ
TVLFDPAIATLLAEGHRAFVEVSPHPVTTVPIAQTVDAAAVPAVVTGTLRRDQDSPRRFL
VSLASLHAGGVELDWPRVFAGLGVRGRRVGLPTYAFQRERYWLEEPEIPAPIAAAPAASR
PAEAPREPVLAVRDVVARETAAVLGLRDWRRVDDRRTFKDLGFDSIMMVELRDRVNRALG
ARLDTTEIFSHPTAAQLSERVELDLGLRTPDTGSAAPAAAEAGDPIVIVGTACRFPGGVA
SPEDLWDVVATGRDVISGFPADRGWDLAALRDGGSATELGGFLHDAPEFDAGFFGISPRE
ALAMDPQQRLLLETSWEALERANITPASLEGTRAGVFVGAYAQGYLQRRARTDDELAGYL
LTGTSSSVMSGRVAYALGLAGPAVTVDTACSSSLVALHLAVQSLRSGESDLALVGGVTVM
SEPDIFEEFSRQGGLAPDGRCKPFADSADGTGWSEGTGVLVVERLSTARAQGHRVLAVVR
GTAINQDGASNGLTAPNGTAQQRVIRDALARAGLSGADVDAVEAHGTGTRLGDPIEAQAL
LATLGQGRGEGEPVWLGSVKSNIGHTQAAAGVAGVIKMVEAMRHGVLPRSLHAERPTTRV
DWDSGAVRVLTEQVRWPETGRPRRAGVSAFGISGTNAHVILEQPPAEPALAVRPEVHTPV
PIVVSGQSEPALRAQAARLAAFVERAPEVAQADLAWSLVTARSTFDHRAVVVPADRAGLL
SSLAALAGGDRTGVVPGSTGRVALVFSGQGAQRVGMGRALAARFPVFAEALDEVCALLDP
VLAGESALREVMFGEAELLDQTGYTQPALFAWQTAWSRLLVSWGIRPDFVLGHSIGEIAA
AHAAGVFSLEDACTLVAARANLMQALPAGGAMLAVSAADSEIAPLLEDYDGTVGIAAVNA
GHAVVLSGDEAAVADLGRLLGERGHKTTRLRVSHAFHSARMDPMLAEFRAAIAGISFHEP
VVPLVANLTGEIAGPEVSTVDYWVRHVREPVRFAAGVATVDGRGARVFVEAGPASTLASM
LGAELDPERASVIPAVRKDQDEVTGALDAVARLHALGATVDWAEVFAGLAVEGRHVAVPT
YAFQRERFWPATADSAGDVGSAGLEPVDHPLLGAGTALPDADGHVFSGRLSTATRPWLAD
HAANGVVLLPGTAFVEVVIRAGDAVGCGRIDDLTLHEPLVLPEDDAVDLQVLVGGPEADG
ARAVTVYSRPAGQDDSWTRHASGTVTPTADVEAVEAGADLAWPPRNATPVSLDGFYGSAG
RSAFDYGPVFQGLQAVWTRGSEVFAEVAVPAAARELVPRFGLHPALLDAVLQANVFAPLA
PAEHGRMPFSFSGVTLHATGATTLRVRLTATGEDLIRVDAVDPAGAPVITIESLALRPFA
PELLSRAAAAGAPETLLRLDWTAVPAPSPAAAGTWWALAGFHGEIPDGLDVANDVAELVA
AGARDVVVPVAGSGGDPEGTSSGDIAEETRAMTAAVLDLLRSWLAQPALAEARLVFLTRR
AVGTTDAEPVEDLAAAAVWGLVRSAQTEHPDRFTLLDHDRLLLTPARLTTAEPQSALRGD
RTLVPRLAVASDAELLALPADSGAVDDAPAAWRLAVSEPGTVDNLVLRAAPDLTEPLGPG
QVRIAVRVAGLNFRDVLNALGMYPGDPVPLGLEVAGVVTETGPEVTELTVGDRVLGIAPG
GLGPVAVADQRSLVAVPRQWSFAQAATAPVVFLTAWHGLRDLAGLRAGESVLIHAGAGGV
GMAAIRLARHLGAEVFATASPGKWAVLRSLGLPDDHLASSRTADFEARFSAATGGRGVDV
VLNSLTGEFVDASLRLLAPGGRFVEMGKVDLRAAHEVAAAHPGVFYQAFDLMEVDLDRIH
RMLAELAGLFASGALVPLPVKTWDVRRAPEAFRFVSQAKHVGKVALTIPRAPDPEGAVVI
TGGTGGLGAAVARHFVERRGARRLVLISRRGEAAPGAAELRAELAAHGAEVVIEACDVAD
HDRLAEVLAAARPVTAVVHTAGVVADATVESLTPEALGRVLAPKVRGAWHLHELTRDTDL
AAFVLFSSIGGVTGAAGQANYAAANGFLDALASLRRGEGRPAVSVAWGAWSPEAGMTAAL
SEVDLHRLTRSGLPPLTVEQGLALFDRALAADRPLSVATRLDRKAVSAQPSRLFEALTTR
PAARIGAATEDPASAEAGVSMARRLAALTPADRARTLTNLVRAEVAAVLGHAVPGDLDPA
QAFKELGMDSLTSVELRNRVNKVFGIRLPATEIFNHPTTAQLADRVGGELGLRQEEAAPA
VTAVRVLDDDPIVIVGMGCRFPGGADSPEDLWDLVAAGRDAISGFPADRGWDLAALRGGG
SATAQGGFLHEAPDFDADFFGISPREALAMDPQQRLLLEVSWEALERAGIAPDSVGGTRA
GVFVGAYHQDYLRERTPARDELGGYLLTGTTSSVLSGRIAYSLGLEGPAVTVDTACSSSL
VALHWAAQSLRSGECDLALVGGVTVMSTPDIFEEFSRQDGLSADGRCKPFADAADGTGWG
EGVGVLVVERMSAARAAEHRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVITAALAKAGV
RAAEIDAVEAHGTGTRLGDPIEAQALLATLGQGREEDRPLWLGSVKSNIGHTQAAAGVAG
IIKMVQAMAHGILPRSLHVDEPSSRVDWTSGAVRVLTEQVAWPETGRPRRAGVSGFGISG
TNAHVILEQAPGEPASVSTVDTTRTAEAADLAETPVPVPVSGRSDSAVREQAARLVRLLE
RKPDLAVADLAWSLATTRSSLDHRAVVVAADRAELAPKLRALAAGEPDPAVVTGTAATSG
GVVFVFPGQGSQWTGMGRELLETAPVFREWILKCQDALAPWVDWSLVDVLTGDSAEPADR
VDVVQPVLWAMMVSLAQLWRSFGVQPDAVVGHSQGEIAAACVAGALSLEDGARVVALRAQ
ALLEIAGQGGMLSVALSPDEVQPWLDREEGRVSPAAINAAASVVLAGDAPALERLREEMT
EQGIRARRVEVDYASHSPAVEQVRDRVLAALAPITRRTADLKFLSTVDTSWHDGTELDAY
YWYRNLRRTVRFEPAVRKLLADGYQTFVEVSAHPVLTVPLAETIEDAGARAVVTGTLRRD
RGSVRRVLTSLAAVHTAGVAIDWPRVFGTGRRRVELPTYAFQHQRFWPTSEPAEALAGWG
YDVVWTPAPQPAPAQPSGVWWLVVPGGCEAAPSVTALRRELADAGATAELVVVAPGRADR
ATLAARFGEPATPTGVVSFLAWPDTSVADGAEVPRGLALTATLLQALGDASIQAPVWVVT
RGAIGVADLAEVAHPAQTAIWGWGRTAAVEYPRRWGGLIDVPADDADPGLAASVAQILRS
GGGTEDQLAVRASGIWARRLAHRDLPPADGSDWEFPAGGSVLVTGGTGALGAHVARWLAT
GGVPHLVLVSRRGPAAPGAAELEAELTALGARVTVVAGDAADREAMAEVIAAIPADLPLA
GVVHTAVVVDDGIIDTVTGEQRTAVFRPKVEAAVVLHELTRDLDLAMFVMFSSISATLGG
VGLSTYAAANAYLDGLAQHRRAHGLPATSVAWGTWSGDGLASASAAQQNLRRFGMITMAP
DAALEALRRVLGRGEATAVIADVDWRQYLAVFTAARPSPLLGDLPETRQSSTDPEDTGAN
LALDPAVRLRTRLAGLARTDQVRIVLDLVRVQLAAILGYGDAEPIPENRAFRDLGFDSLT
AVELRNILSMATGLDLPRTLVFDYPTPTDLARHLLDELAEPEVSAPAVLVPAQPHPDDDP
IVVVGMGCRFPGGVTSPEELWDLVADGADAISEFPADRGWDLAGLHAGGSTTRLGGFLDE
VAGFDAGFFGISPREALAMDPQQRLLLETSWEALERAGIKPGSLRGTRTGVFVGSSIQDY
IHASMQVREDLEGYLLTGSSSSVLSGRVAYLLGLEGPAITVDTACSSSLVTLHLAAQSLL
SGECDLALAGGVTVMSTAELFLDFTRQGALSVDGRCKAFAETADGAGFSEGVGVLAVERL
SSARAAGRRVLAVVRGSAVNQDGASNGLTAPNGPSQQRVITAALARAGVSAREIDAVEAH
GTGTRLGDPIEAQALLATLGQDREDGRPVWLGSVKSNIGHTQAAAGVAGIIKMVQAMRHG
VLPRTLHVDEPTTHVDWAAGAVRVLTEQIPWPETGRPRRAGVSGFGISGTNAHVILEQAP
GEPESVTAVTTMDTADTGEAGVPVPIVLSGQSEAAVRAQAARLADFVDRETGVAVPDVAW
SSVTTRSAFDHRAVVVAADRAEAVASLRALAAGEPGPGAVTGEARAGGGVVFVFPGQGSQ
WAGMGRELLATSAVFRESLRECQDALAPWVSWSLTEVLDRADLLERVDVVQPALWAVNVS
LAKLWRSHGVEPGAVIGHSQGEIAAACVAGALSLEDGARVVALRAQALRVLAGHGGMLSV
ALSQDDAREWLARYEGQLSLAAVNAPGSVVVAGDTAALAHLQEELTRQDIRARRIEVDYA
SHSPEVEQVRVQVLEKLAPITPRPAEVKFFSTVDEKWLDGTELDADYWYRNLRRTVRFEP
AVRALLADGYRAFVEVSSHPVTTVPLTETADAAGTPVVVTGTLRRDQGSPRRFLTSLAGL
FAAGTELDWAAVFAGLGTGGKPVDLPTYAFQHQRYWPELTVRSVAGSPVEDLVLTLDWIT
APEPAGAEAGTWWLLGDHDGASDLPAEPGISRVVDDLGELGKLLAAGDRAPDALLVPVRG
PAGDLTTAVEALTVEVLVLLQQWLAEPEFAGTRLVFLTRDAVSAEAAPDPAAAAIWGLVK
SAQAEHPDRFTLVDHDRHPLSGESLAAALATGEPQVAIRDGRVTVPRLAPAAEPDSPAPV
RWDRGTVVITGGTGGLGAALARHLVASGRVTRLLLLNRRGLDAPGAEQLRAELIDLGAEV
TIAACDLADRARLAEALDAVRPVSAVVHTAVQVADGTIESLTPEAVGRVFEAKVRGAWHL
HELTRGDDLAAFVLFSAMAGVMGTPGQGNYAAANMFLDALARHRRAAGLPAVSMDWGTWT
SDVGLASALSETDLRRLARTGFPAMGIDDGLALFDRAMTVDGPVVAPARVDRVAAAAQPS
RMLENLVVRRPEPGDTAAEPEAGPRLAERLTAMTPTDRVRTMTDLVRGQVAAVLGHATPD
DVQPTQAFKDIGMDSLTSVELRNRLNEATGLRLPTTIAFDNPNPEVLAGHLVGELIGTTA
VAVAVTGSVTTRLDALETTFLTIALDTSARPMLRKRLRALLGRIDDDTTTTETPVSTVDT
ATDEDLFAMLDDQLGQ
NT seq 18231 nt   +upstreamnt  +downstreamnt
gtggtgaattcgtcggggtccggcctcggggacggcccgatcgccatcgtcggcatggcg
tgccggctgccgaaggcgtcgaacccgcgtgagttctggcagttgctccactccggcggc
agcggcgtcacgccggtgcccggcggccggtggaccgggctggccggaccggacgccgag
ctcctgcggtacggcgggttcgtcgacgacgtggaccggttcgacgccgagttcttcggg
atctcgccgcgggaagccgcggtgatggacccgcagcagcggctggcgctggagctgggg
tgggaagcgttcgaggacgcggggctcgtgccggcgcgtctgcgcgggcgccgggtcggg
gtcttcgccggcgcgatggcggcggactacgagctgctcagcctgcgccggggcgcgatc
ggccaccacagcctgaccggcctgcgcaccgggatgatcccgaaccggatgtcgtacgcg
ttcgggttcaccgggccgagcctcgccgtggacaccgggcagtcgtcgtcgctggtcgcc
gtgcacctcgcggccgagagcatccgctccggcgagtcggatctcgccctggcgggcggc
atccagctgaacttggccggtgacaacgctgtcaccaccgcgcggttcggcggcctgtca
ccggacggccggtgcttcaccttcgacgcccgcgccaacggttacgtgcggggcgagggc
ggcgggttcgtcgtgctcaaaccgctgtccctcgcgctggaggacggcgacgacgtgtac
gccgtgctgctgggcagcgcggtgaacaacgaggggccgggggagtcgttcacccggccg
agcgccgaggcccaggaagccgtgctccgcgcggcctaccggcgcgccggcgtggatccc
ggccgcgtgcagtacgtggagctgcacgggaccggcacgaaggtgggcgacccgatcgag
gcccgcgcactcggcgcggcgctgggcgagggccggaccaccccgctgtccgtggggtcg
gcgaagaccaacgtgggacacctggagagcgcggccggcatcgtcgggctcgtgaagacc
gccttggcggtgcgcaaccgccgcctgcccgcgagcctgaacttcgagcagcccaacccg
gacatccggttcgatgagtggcagctgcgggtcgtgccgtcggccgaggcttggccggag
gtcgaagggccgctgctggctggcgtctcgtcgttcggcgtgggcggcacgaactgccac
gtcgtcctctcgtcgccgcacccggcggcgcccgcgcgcgagcacaccgggatgccgtcc
gccgaatccgtggtgccggtgctggtgtcgggccggtcgcaggcggccctgcgcgaccag
gcggcgcggctcgccgacgcgctggacgcggaggccggcctggcagtggcggatctcgcc
tggtcctcggcactgacccgatcgggcttcgagcaccgggccgtggtcgtgacgggtgac
cgggccgaggcgtcggcgggcctgcgggcactggcggccggcgagcccgatccggcggtg
gtgaccggcgtggccgcgccgtcgcgcggggtggtgttcgtgtttcccggccagggctcg
cagtggccgggcatgggccggggcctgctggagacctcgccggtgttccggcagtcgatg
ctcgagtgccaggaggccttggcgccctgggtgtcctggtcgctgatcgacgtgctgacc
ggcaccgacggcaccgacggcgccgcgctggaccgcgtcgacgtggtccagcccgccctg
tgggcgatcatggtctccctgtcccgcctgtggcgttcgtgcggtgtcgaacccgacgcg
gtcgtcggccacagccagggcgagatcgcggcggcctgtgtggccggcgcactgtccctt
tcggacggtgcccgcgtggtggcgctgcgggcccgggcgttgcgcacgctcgccgggcgc
ggcggaatgctgtcggtggacctgtcccgcgacggcgtcgaggagtggctcggccggtac
cccggccgggtgtccctggccgcggtcaacgccaccggctccgtcgtgctcgcgggcgag
ccggaagcactgcggctgcttcgggacgagctgaccgcgcaggacatccgcgcccggctc
gtcgacgtcgactacgcctcgcactccgcacaggtcgacgaggtgcgtgccgaggtgctc
gaggccctggcgccgatcgagccccggcccgcgcgggtgccgttcttctccactgtggac
gccgggtggctgcggggcacggaggtcgacgccgcgtactggttccggaacctgcgccag
accgtgctgttcgacccggccatcgccaccctgctggccgaggggcaccgggcgttcgtc
gaggtgagcccgcacccggtgaccacggtgccgatcgcgcagaccgtcgacgcggcggcg
gtgcccgccgtcgtgaccgggacgctgcgccgcgaccaggattcgccgcggcggttcctg
gtgtcgctggcgagcctgcacgccggcggcgtcgagctcgactggccgcgggtgttcgcc
gggctcggtgtgcggggccgccgcgtcggcctgcccacctacgcgttccagcgggagcgc
tactggctcgaggagccggaaatcccggcgccgatcgccgcggcaccggcggcgagccgg
cccgccgaggcaccgcgggaaccggtgctggcggtgcgggacgtggtggcgcgcgagacc
gccgccgtgctggggctgcgggactggcgccgggtcgacgaccgccgcaccttcaaggac
ctcgggttcgactcgatcatgatggtcgagctgagggaccgcgtgaaccgggcgctcggc
gcccggctggacaccaccgagatcttcagtcaccccaccgcggcgcagctgagcgagcgc
gtggagctcgacctcgggctgcgcacgccggacaccgggtcggcggcgcccgccgcggcc
gaggccggcgacccgatcgtgatcgtgggcacggcctgccggttcccgggtggggtcgcc
tcgcccgaagacctgtgggacgtggtcgcgaccggccgcgacgtgatctccgggttcccg
gccgaccgcggctgggacctggccgcactgcgcgacggtggctccgcgaccgagctgggc
gggttcctccacgacgcgcccgagttcgacgccggcttcttcgggatctcgccgcgggaa
gcgctggccatggacccgcagcagcggctgctgctcgaaacgagctgggaagcgctggag
cgggccaacatcacgcccgcgtcgctcgaagggacgcgggcgggggtgttcgtcggcgcc
tacgcccaggggtacctccagcggcgggcccgcaccgacgacgagctggccggctacctg
ctcaccggcacgtcgtcgagcgtgatgtcgggccgcgtcgcctatgcgctcgggctggcc
ggtccggccgtcacggtggacacggcgtgctcctcgtcgctggtcgccctgcacctggcc
gtgcagtcgctgcgctccggcgaatcggacctggcgctggtcggcggcgtgacggtgatg
tcggagccggacatcttcgaggagttctcccggcagggcgggctggcgcccgacggccgg
tgcaagcccttcgccgactcggccgacggcaccggctggagcgagggcaccggggtcctg
gtcgtcgaacggctgtcgacggcccgggcgcaggggcaccgggtgctcgccgtcgtccgc
gggaccgcgatcaaccaggacggcgcgtccaacggcctcaccgcgcccaacggcacggcc
cagcaacgggtgatccgcgacgcgctcgctcgcgccgggctgtcgggcgccgacgtggac
gccgtggaggcgcacggcacgggcacccggctcggtgaccccatcgaggcgcaggcgctg
ctggcgaccctgggccagggccggggcgagggcgaaccggtgtggctcggctccgtgaag
tcgaacatcgggcacacgcaggccgcggccggggtcgcgggcgtgatcaagatggtcgag
gcgatgcggcacggcgtgctgccgcgcagcctgcacgccgagcggcccaccacccgggtc
gactgggactccggtgcggtgcgggtgctcaccgagcaggtgcggtggcccgagaccggc
cggcctcgccgggcgggagtgtcggcgttcggcatcagcggcacgaacgcccacgtgatc
ctcgagcagccgcccgccgagccggcgctcgcggtgcggccggaggtgcacactcccgtg
ccgatcgtcgtgtccggccagtccgagccggcgctgcgggcgcaggcggcgcggctggcg
gcgttcgtcgagcgcgcgccggaggtggcgcaggcggatctggcctggtccctggtcacc
gcgcgttcgaccttcgaccaccgcgcggtggtcgtgcccgccgatcgcgccggactgctg
tcgtcgctggccgcgctggccggcggtgaccggacgggggtggtgcccggcagcacgggg
cgcgtggcgctcgtcttttccgggcagggcgcgcagcgggtggggatggggagggcgctg
gcggcgcggttcccggtgttcgccgaggccctcgacgaggtgtgtgcgctgctcgatccg
gtgctggccggtgagtccgcgttgcgtgaggtgatgttcggcgaagcggaattgctggat
cagaccgggtacacgcagccggcgttgttcgcgtggcagacggcgtggtcgcggctgctg
gtctcgtgggggattcggccggacttcgtgctggggcactccatcggtgagatcgccgcg
gcgcacgcggcgggcgtgttctccctcgaagacgcgtgcacgctggtcgccgcgcgggcc
aacctcatgcaggccctgccggccggcggggcgatgctcgccgtcagcgccgcggacagt
gaaatcgctccgctgctggaggactacgacggcacggtggggatcgcggctgtgaacgcc
gggcacgcggtggtgctgtcgggcgacgaggccgccgtcgcggacctcggccggctgctg
ggcgagcgggggcacaagaccacgcggttgcgggtgagccatgccttccactcggctcgg
atggacccgatgctggcggagttccgcgcggcgatcgccgggatctccttccacgagccg
gttgtcccgctggtcgccaacctcaccggtgagatcgccggtcctgaggtgtccactgtg
gactactgggtccggcacgtgcgggagccggtgcgcttcgccgccggagtggccactgtg
gacggacgtggcgcgcgggtgttcgtggaggcggggccggcgagcacgctggcgtcgatg
ctcggcgccgagctcgatcccgagcgcgcctcggtgatccccgcggtccgcaaggaccag
gacgaggtcaccggcgccctcgacgccgtcgcccggctgcacgcgctgggcgccaccgtg
gactgggccgaggtgttcgcggggctggccgtggaaggccgccacgtcgcggtgccgacg
tatgcgttccagcgcgagcggttctggcccgcgaccgcggattccgcgggcgacgtgggc
tcggccggcctggagccggtggaccacccgttgctcggcgcgggcaccgcgttgcccgac
gccgacggacacgtgttcagcggccggctgtcgacggcgacccggccctggctggccgac
cacgcggcgaacggcgtggtgctcctccccgggaccgcgttcgtcgaggtcgtgatccgg
gcgggcgacgcggtcgggtgcggccggatcgacgacctcaccctgcacgagcccctcgtc
ctgcccgaggacgacgccgtcgacctgcaggtgctggtcggcgggcccgaggccgacggc
gcccgcgcggtcacggtgtactcccgccccgccgggcaggacgactcgtggacgcggcac
gcgagcggcacggtcacgcccaccgcggatgtcgaggccgtcgaggccggcgcggatctc
gcgtggccgccccggaacgcgacgccggtgtctttggacgggttctacgggtccgccggc
cgatcggcgttcgactacgggcccgtgttccagggccttcaagcggtgtggacccgcggg
agcgaggtgttcgccgaggtcgcggtgccggcggcggcacgcgagctggtaccgcggttc
ggtctgcacccggcgttgctggacgcggtgctgcaggccaacgtgttcgccccgctggcc
ccggccgagcacggaaggatgccgttctccttcagcggggtcaccttgcacgccaccggg
gccacgacgttgcgggtccggctgaccgcgaccggcgaggacctgatccgcgtcgacgcc
gtcgacccggccggcgcccccgtgatcacgatcgagtcgctggcgctgcggcccttcgcg
cccgagttgctcagccgcgccgcggccgcgggtgcgccggagacgctgctccggctcgac
tggactgccgtgcccgcgccgagcccggcggccgccgggacctggtgggcgctggcgggt
ttccacggcgagatcccggacggcctcgacgtggcgaacgacgtggccgagctcgtcgcg
gccggtgcgcgtgacgtagtggtaccggtcgccggttccggcggggacccggaggggacc
agcagcggggacatcgccgaagaaacccgcgcgatgaccgcggccgtgctcgacctgctg
cggtcgtggctcgcgcagccggcgctggccgaggcccgactggtgttcctgacccggcgc
gccgtcggcacaaccgacgccgaacccgtcgaggacctcgccgccgccgccgtgtggggc
ctggtcaggtccgcccagaccgagcaccccgaccggttcacgctcctcgaccacgaccgc
ctgctcctcaccccggcgcggctcaccacggccgagccccagtcggcgctgcgcggcgac
cggaccctggttccgcgactggccgtggcctccgatgccgagctgctggccttgcccgcc
gactcgggagccgtcgacgacgcgccggccgcgtggcggctggcggtgtccgagccgggc
acggtcgacaacctcgtgctgcgcgccgcccccgacctgaccgaaccgctcggccccggc
caggtccggatcgcggtgcgcgtcgccgggctgaacttccgcgacgtgctcaacgcgctc
ggcatgtacccgggcgatccggtgccgctgggtctcgaggtcgccggcgtggtgaccgaa
acgggccccgaggtcactgagttgaccgtcggcgatcgggtgctggggatcgcgcccggc
gggctgggcccggtcgcggtggccgatcagcgctcgctcgtcgcggtaccgcggcagtgg
tcgttcgcccaggcggcgacggcgccggtggtgttcctgaccgcgtggcacggccttcgt
gacctggccgggctgcgggcgggggaatcggtgctgatccacgccggtgccggcggggtc
gggatggccgcgatccggctggcccgccacctgggcgccgaggtgttcgccacggcgagc
ccgggcaagtgggccgtgctgcggtccctcggcctgcccgacgatcacctcgcctcctcg
cgcaccgcggacttcgaggcgcggttctcggcggcgaccgggggccgcggggtggacgtg
gtcctcaactccctcacgggcgagtttgtggacgcgtctctgcggctgctcgcccccggc
ggccggttcgtggagatgggcaaggtcgacctgcgcgccgcgcacgaggtcgccgcggcc
catccgggtgtgttctaccaggcgttcgacctgatggaggtcgacctggaccggattcac
cggatgctggccgagctcgccgggttgttcgcctcgggagcgctggttccgctgccggtc
aagacctgggacgtccggcgcgcacccgaagcgttccggttcgtgagccaggccaagcac
gtcggcaaggtcgcgttgacgatcccgagggctccggaccccgagggcgctgtggtcatc
accggtggcaccggcgggctgggggccgcggtggcgcggcacttcgtcgaacggcgtggc
gcgcgcaggctggtgctgatcagccggcggggcgaggcggcgccgggggcggccgagctt
cgggccgagctggccgcccacggtgccgaggtcgtgatcgaggcgtgcgacgtcgcggat
cacgaccggctggccgaggtgctggctgccgcgcggccggtgacggccgtggtgcacacc
gcgggggtcgtggcggacgcgaccgtcgaatcgctgacccccgaggcgctcggccgcgtg
ctggcgccgaaggtgcgcggcgcgtggcacctgcacgagctcacccgcgacaccgacctg
gcggcgttcgtcctgttctcttccatcggcggtgtcacgggcgccgccgggcaggccaac
tacgccgcggccaacgggttcctcgacgcactggcctcgctgcgccgcggcgagggtcgc
cccgcggtgtcggtggcgtggggtgcgtggtcgccggaagcggggatgaccgccgcactg
tccgaagtggacctccaccggctcacccggtccgggctgccgccgctgacggtcgagcag
gggctcgcgctgttcgaccgggctctcgccgcggaccgcccgctgtcggtcgcgacccgg
ctcgaccgcaaggcggtgtcggcgcagccctcgcggctgttcgaggccctcaccaccagg
cctgcggcccggatcggcgcggcgaccgaagacccggcttcggccgaggccggggtctcg
atggcccgccggctggcagcgctgaccccggccgaccgcgcgcggaccctcacgaacctg
gtccgcgccgaggtggccgcggtgctcgggcacgccgtgccgggcgacctcgatcccgcc
caggcgttcaaggagctgggcatggactccctgacgtcggtggagctgcgcaaccgcgtg
aacaaggtgttcgggatccgactgccggccaccgagatcttcaaccaccccaccacggcg
cagctggccgaccgcgtcggcggcgagctcggcctccggcaggaggaagccgccccggcg
gtcaccgccgtccgggtgctcgacgacgacccgatcgtgatcgtcgggatgggctgccgg
ttccccggtggcgccgattcgccggaagacctgtgggacctcgtcgccgccggccgggac
gcgatctccgggttcccggccgaccggggctgggacctggccgcgttgcgcggcgggggc
tcggccacggcgcagggcgggttcctccacgaggcccccgacttcgacgcggacttcttc
ggcatctcgccccgtgaagcactggccatggacccgcagcaacggctgctcctggaagtt
tcctgggaggcgctggagcgcgcggggatcgcgccggactccgtcggcgggacgcgggcc
ggggtgttcgtcggcgcgtaccaccaggactacctccgcgagcggaccccggccagggac
gaactcggcggctacctgctcaccggcaccacgtcgagcgtgctctcgggccggatcgcg
tactcgctcgggctggaaggcccggcggtgaccgtcgacacggcgtgctcgtcttcgctg
gtggccctgcactgggcggcgcagtcgctgcgctcgggcgagtgcgacctggcgctcgtc
ggcggcgtcaccgtgatgtccactccggacatcttcgaggagttctcccggcaggacggg
ctctccgccgacggccggtgcaaaccgttcgccgacgcggcggacggcaccggctggggt
gagggggtgggtgtcctcgtcgtggaacggatgtccgcggcccgcgcggccgagcaccgc
gtgctggccgtggtgcggggttcggcggtgaaccaggacggcgcgtccaacggcttgacc
gcgcccaacggcccgtcgcagcaacgggtcatcaccgccgcgctcgctaaggcgggggtg
cgggcggcggagatcgacgccgtcgaggcccacggcaccggcacgcgcctcggtgatccc
atcgaggcccaggccctgctcgccactctcggtcaggggcgggaagaagatcggccgctg
tggctgggttcggtgaagtcgaacatcgggcatacgcaggccgcggccggtgtcgcgggg
atcatcaagatggtgcaggccatggcgcacgggatcctgccgcgcagcctgcacgtcgac
gagccgtccagccgagtcgactggacttccggtgcggtgcgggtgctgaccgaacaggtc
gcctggccggagacgggccggccgcgccgggccggggtgtccggcttcggcatcagcggg
accaacgcgcacgtgatcctcgaacaggcacccggcgaacccgcctctgtgtctacagtg
gacaccacgcgcacggcagaagcggcagacctcgccgagacgccggtgccggtcccggtg
agcggccggtcggactcggccgtgcgggagcaggccgcgcggctggtgcgcctgctggag
cggaaacccgacctggccgtggcggacctcgcctggtcgctggcgaccacgcggtcgagc
ctcgaccaccgggccgtcgtggtggccgcggaccgggccgagctggctccgaagctgcgg
gcgctggccgccggcgagccggacccggccgtggtgaccgggaccgccgcgacctccggc
ggggtggtgttcgtgttccccggccagggttcccagtggaccggcatgggccgggagctg
ctggagaccgcacccgtcttccgggagtggatcctcaagtgccaggacgcgctggcgccc
tgggtggactggtcgctggtcgacgtcctcaccggtgacagcgccgaaccggccgaccgg
gtggacgtggtccagccggtgctgtgggcgatgatggtgtcgctggcgcagctgtggcga
tccttcggcgtgcaaccggacgcggtggtcggccacagccagggcgagatcgcggccgcc
tgcgtcgccggcgcgctgtcgctcgaggacggtgcgcgggttgtggcgctgcgcgcgcag
gccctgctcgaaatcgccggccagggtggcatgctctcggtcgccctgtcgccggacgag
gtgcagccctggctcgatcgtgaagagggccgggtgtcgccggccgcgatcaacgccgcg
gcgtccgtggtgctcgccggcgacgcaccggcgctggagcgccttcgcgaagagatgacc
gagcaggggatccgggcgcggcgcgtggaggtggactacgcctcgcactccccggccgtc
gaacaggtccgggatcgggtgctggccgccctggcgccgatcacccggcgcaccgccgac
ctcaagttcctgtccacagtggacaccagctggcacgacgggaccgagctggacgcctac
tactggtaccggaacctgcgccggacggtccggttcgagccggccgtgcgcaagctgctg
gccgacgggtaccagacgttcgtggaggtgagcgcgcacccggtgctcaccgtgccgctc
gccgagaccatcgaggacgccggggcgcgtgcggtggtcacgggaacgctgcgccgggac
cgggggtcggtgcggcgcgtgctgacgtcgctcgcggccgtgcacacggccggcgtggcg
atcgactggccccgggtgttcggaaccgggcgccgtcgggtcgagctgcccacgtacgcc
ttccagcaccagcgtttctggccgacttccgagccggccgaagcgttggcgggctggggt
tacgacgtggtctggaccccggccccgcaaccggcgccggcccagccgtccggcgtgtgg
tggctggtcgtgccgggcggctgcgaagccgcgccgtcggtcaccgcgttgcgccgggaa
ctggccgacgccggcgcgaccgcggagctggtcgtggtcgcgcccggccgggcggaccgg
gcgacgctcgccgcgcggttcggcgaaccggccacgccgacgggcgtggtgtcgttcctg
gcctggcccgacacgtcggtcgcggacggcgccgaggtcccgcgtggcctggcgctcacc
gcgaccctcctgcaggcgctgggtgacgcctcgatccaggccccggtctgggtcgtgacc
cgcggtgcgatcggcgtggccgacctcgccgaggtggcccaccccgcgcagacggcgatc
tggggctggggccggaccgcggcggtggagtacccccggcgctggggcggcttgatcgac
gtaccggccgacgacgccgacccgggcctggccgcgagcgtggcgcagatcctgaggtcc
ggcggcggcacggaggaccagctcgcggtccgcgcgtccgggatctgggcccggcggctg
gcccatcgcgacctcccgccggccgacggatcggactgggagttcccggctgggggcagc
gttctcgtgacgggtggcaccggagcgctgggcgctcacgtcgcgcggtggctggccacc
ggcggggtcccgcacctcgtgctcgtcagccgacgtggcccggcggcgccgggcgcggcc
gagctggaagccgagctgacggcgctcggggcccgcgtgacagtggtggcgggtgacgcg
gccgaccgcgaagcgatggctgaggtgatcgccgcgatcccggcggacttgccgctggcc
ggggtcgtccacaccgccgtggtcgtcgacgacgggatcatcgacaccgtcaccggcgag
cagcggaccgccgtgttccggcccaaggtcgaggccgcggtggtgctgcacgagctcacc
cgggatctggacctcgcgatgttcgtgatgttctcctcgatcagcgccacgctcggcggc
gtcgggctcagcacgtacgcggcggccaacgcctacctcgacggactggcccagcaccgc
cgggcccacggccttcccgcgacttcggtcgcgtggggcacgtggtcgggcgacggcctg
gcgtccgcgagcgcggcccagcagaacctgcgccggttcggcatgatcaccatggcaccc
gatgccgcgctcgaagccctgcgccgggtgctcgggcgcggcgaggccaccgcggtgatc
gcggacgtggactggcggcagtacctcgccgtgttcacggccgcacgccccagcccgctg
ctcggtgacctccccgagacgcgtcagtccagcacggatccggaggacaccggggcgaac
ctggcactcgacccggcggtgcggctgcgcacccggctggccgggctggcgcgcaccgac
caggtccggatcgtgctcgacctggtgcgcgtgcagctggcggccatcctcgggtacggc
gacgccgagcccatcccggagaaccgggcgttccgggatctggggttcgactcgctgacc
gcggtggagctgcgcaacatcctgagcatggccacggggctggacctgccccgcacgttg
gtcttcgactacccgacgcccaccgacctcgcccggcacctgctcgacgagctcgcggaa
cccgaggtgtccgcgcccgcggtcctcgtccccgcgcaaccgcacccggacgacgacccg
atcgtggtggtcgggatgggctgccggttccccggcggcgtgacttcgcccgaagagctg
tgggacctggtcgcggacggggcagatgcgatctccgagttcccggccgaccgcggctgg
gacctcgcgggcctgcacgcgggcggctcgacgacccggctgggcgggttcctcgacgag
gtcgccgggttcgacgccgggttcttcgggatctcaccccgggaagcgctggcgatggac
ccgcagcagcggctgctgctggagacctcctgggaggcgctggaacgggccgggatcaag
ccgggctcgctgcgcggcactcgcaccggggtgttcgtcggttcgagcatccaggactac
atccacgcgtcgatgcaggttcgtgaggacctcgagggctacctgctcacgggcagctcg
tccagcgtgctctcgggccgggtcgcgtacctgctcggtctcgaaggcccggcgatcacc
gtcgacacggcgtgttcgtcgtcgttggtcacgctgcacctggcggcgcagtcgctgctg
tcgggcgagtgcgatctggcgctggccggcggggtcaccgtgatgtccacggccgagctg
ttcctcgacttcacccgccagggcgcgttgtcggtggacgggcggtgcaaggcgttcgcc
gagacggccgacggtgccgggttctccgagggagtcggtgtgctcgcggtcgagcggctt
tcgtccgcgcgggcggcgggccgccgagtgctggcggtggtgcggggttcggcggtgaac
caggacggcgcgtccaacggcttgacggccccgaacgggccgtcgcagcagcgggtgatc
actgccgcgctggctcgggccggcgtgtcggcgcgcgagatcgacgcggtggaggcacac
ggcacgggtacgcgcctcggcgacccgatcgaggcgcaggccttgctcgccacgctcggt
caggaccgggaggacggccggccggtgtggctgggttcggtgaagtcgaacatcgggcac
acgcaggccgcggccggtgtcgcggggatcatcaagatggtgcaggcgatgcgccacggg
gtgctgccgcggacgctgcacgtggacgagcccaccacgcacgtggactgggccgccggt
gcggtgcgcgtgctgacggagcagatcccgtggccggagacgggccggccgcgccgggcc
ggggtgtccggcttcggcatcagcgggaccaacgcgcacgtgatcctcgaacaggcaccc
ggtgaacccgagtccgtgaccgcagtgaccacaatggacacagcggacacgggagaagcc
ggagtgccggtgccgatcgtcctttcgggacagtccgaggcggcggtacgggcgcaagcc
gccaggctggccgacttcgtggaccgcgagaccggcgtggcggtgcccgacgtggcctgg
tcgtcggtgacgacccggtcggcgttcgaccaccgggccgtggtggtggccgcggaccgg
gccgaagcggtggcgagcttgcgtgcgctggctgcgggcgagccgggtccgggtgccgtg
accggcgaggcgcgggcgggcgggggcgtggtgttcgtgttcccgggtcagggttcgcag
tgggcggggatgggccgggagctgctggcgacctcggcggtgttccgggagtcccttcgg
gagtgtcaggacgcgttggcgccgtgggtgtcctggtcgctgaccgaggtgctcgaccga
gccgacctgctggagcgggtcgacgtggtccagccggcgctgtgggcggtgaacgtttcg
ctggcgaagctgtggcggtctcacggggtcgagcccggcgccgtgatcgggcacagtcag
ggcgagatcgccgccgcctgtgtcgcgggcgccctttcgctggaagacggcgctcgcgtg
gtcgccctgcgggcgcaggcgctgcgggtgctggccggccacggcggaatgctctcggtc
gcgctgtcgcaggacgacgctcgcgagtggctcgcccgctacgaggggcagctgtcgctc
gccgccgtcaacgcgccgggctcggtggtggtcgccggcgacacggccgcgttggcgcac
cttcaggaagaactcacccgccaggacatccgggcgcgccggatcgaggtggactacgcc
tcgcactccccggaggtcgagcaggtccgggttcaggtgctggagaagctcgcgccgatc
acgccccgtccggcggaggtgaagttcttctccactgtggacgagaagtggctggacggc
actgagctcgacgcggactactggtaccgcaacctgcgccggaccgtgcgcttcgaaccg
gccgtgcgggccctgctggccgacgggtaccgggcgttcgtggaggtgagctcgcacccg
gtcaccaccgtgccgctcaccgagaccgcggacgcggccgggacaccggtggtcgtcacc
ggcacgctgcgccgtgaccaggggtcgccccggcggttcctgacctcgttggccggcctg
ttcgccgcggggaccgagctcgactgggccgcggtcttcgcgggcctcggcaccggcggg
aaaccggtcgacctgccgacctacgcgttccagcaccagcgctactggccggagctcacg
gtgcgctcagtggcgggatcgccggtggaagacctggtcctgaccctggactggatcacc
gcgccggagccggcgggtgccgaggcaggcacctggtggctgctcggcgaccacgacggg
gcgtcggacctgccggccgagccgggtatctcacgagtggtggacgacctcggcgagctg
ggcaagctgcttgccgccggcgaccgcgcaccggacgcactgctggtgccggtccgcggc
ccggccggcgacctgaccacggccgtggaggccctgaccgtcgaggtactggtgctgctg
cagcagtggctggccgaacccgagttcgccggcacgcgcctggtgttcctgacgcgggac
gcggtgagcgccgaggccgcgcccgatccggcggccgcggcgatctggggcctggtcaag
tcggcgcaggccgagcacccggaccggttcaccctcgtcgaccacgaccggcacccgctc
tccggcgagtcgctggccgcggcactggccaccggggaaccgcaggtcgcgatccgcgac
gggcgggtgacggtcccgcggctcgcgcccgcggccgaaccggactcgccggcgccggtc
cgctgggaccggggcaccgtggtgatcaccggcggcacgggcgggctcggtgccgcgctg
gcccggcacctggtcgcgagcggccgcgtgacccggctgttgctgctcaaccgccgcggc
ctcgacgccccgggcgccgagcagttgcgggccgagttgatcgacctgggtgccgaggtc
acgatcgccgcttgcgatctcgccgaccgcgcccggctggccgaggcgctcgacgcggtg
cggccggtctcggcggtcgtgcacacggcggtgcaggtcgcggacggcaccatcgaatcg
ctgacgccggaagccgtcggccgcgtgttcgaggccaaggtgcggggcgcgtggcacctg
cacgagctgacccggggcgacgacctggcggcgttcgtgctcttctcggccatggccggg
gtgatgggcaccccgggccagggcaactacgccgccgccaacatgttcctcgacgccctc
gcccggcaccggcgggccgcgggcctgccggcggtgtcgatggactggggcacctggact
tccgacgtggggttggccagtgcactgtccgaaacggacctgcgccggctggcccgcacg
gggttccccgccatgggcatcgacgacgggctggcgttgttcgaccgggccatgaccgtc
gacgggccggtggtggcaccggcccgggtcgaccgggtcgcggcggcggcccagccgtcg
cgcatgctcgagaacctcgtggtgcgccggcccgagccgggggacaccgcggccgaaccc
gaggccgggccgcggctggccgagcggctcacggccatgaccccgaccgaccgggtgcgg
acgatgacggacctcgtgcgcggtcaggtcgccgccgtgctcggccacgcgacgccggac
gacgtccagcccacccaggcgttcaaggacatcggcatggactcgctcacctcggtcgag
ctgcgcaaccggctcaacgaggccaccgggctgcggttgccgaccacgatcgcgttcgac
aacccgaacccggaggtgctcgcgggtcacctcgtcggggaactgatcgggaccaccgcg
gtggccgtcgcggtcaccggatccgtgaccacccggctggacgcgctggagaccaccttc
ctgaccatcgccctcgacacctccgcccgcccgatgctgcgcaagcggctcagggcgctg
ctcggccggatcgacgacgacaccacgaccaccgaaacccccgtgtccactgtggacacg
gcgaccgacgaagaccttttcgccatgctcgacgaccagctggggcagtga

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