Amycolatopsis rhabdoformis: VSH64_26515 Help Entry VSH64_26515       CDS       T09694                                  Name (GenBank) type I polyketide synthase   KO K19203   pimaricinolide synthase PimS1 Organism arhd  Amycolatopsis rhabdoformis Pathway arhd01052   Type I polyketide structures Brite KEGG Orthology (KO) [BR:arhd00001]  09100 Metabolism   09109 Metabolism of terpenoids and polyketides    01052 Type I polyketide structures     VSH64_26515  09180 Brite Hierarchies   09181 Protein families: metabolism    01008 Polyketide biosynthesis proteins [BR:arhd01008]     VSH64_26515 Polyketide biosynthesis proteins [BR:arhd01008]  Polyketide synthase (PKS)   Modular type I PKS    cis-AT PKS     Pimaricinolide synthase      VSH64_26515 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  ketoacyl-synt Acyl_transf_1 KR Ketoacyl-synt_C PKS_DH_N PS-DH PP-binding KAsynt_C_assoc CurL-like_PKS_C adh_short SpnB_Rossmann RhiE-like_linker Epimerase Thiolase_N GDP_Man_Dehyd Polysacc_synt_2 3Beta_HSD SDR DUF7080 NmrA Sacchrp_dh_NADP Motif Other DBs NCBI-ProteinID:  WSE26434 LinkDB All DBs Position complement(5779221..5795036) Genome browser AA seq 5271 aa AA seqDB search MSEWDKNPESGFAERLTQVPPGDRAAFVADVVHGATRAALRAVLPEVPAVLDPEKAFSDH GFDSLAAVELHAQLTDATGFDLPVTLAFDHPTPVAVARFLLARVFGEETVDSGLIASGRD DDEPVAIVGIGCRYPGGAASPEQLWQLVADEVHTISGFPTDRGWDLDSLYDPDPDRPGSS YVAAGGFLPDAGEFDAGFFGIAPREASAMDPQQRLVLETAWEALERAKIDPTTLRGTPAG VFIGAEAQEYGPRLHEAPDGLDGYLLTGNAPSVVSGRVAYSLGLEGPTLTVDTACSGSLV ALHLAVQALRRGETHLALAGGVAVMGAPGTFTAFSRQRGLAEDGRCKAFAAAADGTGFAE GVGVLVLERLSDAVANGHTVLAVVRGSAINSDGASNGLTAPNGPSQQRVITRALADAGLA PSEVDAVEAHGTGTRLGDPIEAQALLATYGRDRETPLWLGSLKSNIGHTQAAAGVAGVIK MVEAMRRGVLPKTLHVDAPTPHVDWTAGSVELLTEAREWPSVERPRRAGVSSFGVSGTNA HVIIEQAPAVEAEGEPAELPVVPLLVSARDEEALRAQAAKLASIVDTVDTVDLASIGFSL ATTRAAHDFRAVVVAENTADAVRGLQALAAGEQDAAVVTGERTPGKLAMLFTGQGSQRLA MGRELYLAYPVFAEVFDEALDNLDVQMDQPLRDVLFGDDPEELNHTRYAQCALFAVEVAL ARLLESWGVRPDILLGHSIGELAAAHLAGVWSLTDACMVVAARGRLMQALPEGGAMVALA ATEDEVQPLLNDRVSIAAVNGPSSVVVSGERDAVEDVATVFRLQGRKTSELRVSHAFHSP LMEPMLAEFREILEVVDYAPPTIPVVSNVTGRLATAEELCSPGYWLWHVRRAVRFADGVS TLAEAGVTTAIEVGPDAVLSAMAATGPHAETITFTAAQRRDHAEVTTLAGALGKLHTRGV AVDWPAFFGPARRVDLPTYAFQRKHFWLTAPVSHGDAADLGQLASSHPLLAAEIGLAGDG LVFTGRVGLRTHAWLADHTIAGTAVLPGTAFVEMALHAGEQAGCGVLDELTLQAPLALPE TGGVALQVVVGPEDDGRRSIEFHSRADHDADAAWTRHAVGVLATGPVVEPASLTEWPPAG AEVVATHELYGELAEQGYGYGPLFQGLRTAWRRDDVVYAEVALPAETDTAFGIHPALLDA VLHATDFAPGEAREADEIRLPFAWTGVRLHASGATEVRVRITSPATGGVTLEITDPAGAP VLSVESFRSRAVRGADLGTQARDLLYTVEWTPVTADAELPALAALGSVAGFDVPVADALV SLVDVPPVVLLPVSVRGKNVATAAKQATHRVLAVLRQWLENERYESARLVVLTRGELADS AVRGLVRSAQAEHPGRVVLIEGAVTPATLATALGSGEPELRVDGSAVHAARLVRLTADAE QPAWPAEGTVLITGGTGGLGAQVARHVVTNHGVRSLLLVSRRGADAPGAAELVADLTELG ASVTVAAADVSKKRSLAAALKKAEHPLSAVVHTAGVLDNAMIGSLTEDRLDAVLAPKVDA AWHLHELVGEVDAFVLFSSSAGLADGAGQANYAAGNTFLDALAEHRCTEGKTATSLAWGL WDTEAGMGATLSEVDRSRITRLGLAPLTVAESLAALDAALASGAPAVVPTRVDRSALRAR GEDVPAVLRGLAPAGRRRAAAAVATGELTPEQQFAGRFAHLGEADRDRAVLDLVRTHVAA VLGHDSAEAINPARPFGEIGFDSLAAVELRNILDSVTGMRLPATLVFDYPTPRALAEYLV GRLAGLAPAQPIAPVTTADPEEPIAIVGIACRYPGGVTTPEDLWRLVAEGEEALTTFPAD RGWNVDALYDPEPGKPGHSYVKHGAFLHDAAEFDADFFEISPREAAAMDPQQRLLLEVSW EAFERAGIDPVSLRGSATGVFAGVMYHDWGTRLGTVSDDIAGYLGNGSLASVVSGRVSYA LGLEGPTVTVDTACSSSLVALHWAVQALRRGECTLALAGGVTVMSTPDTFVDFSRQRGLS ADGRCRSFADAADGTGWGEGAGMLLVERLSDARRNGHPVLALLRGSAVNHDGASNGLTAP NGPSQQRVIAKALADAGLAPSEVDAVEGHGTGTTLGDPIEAQALLATYGQEREEPLWLGS IKSNIGHTQAAAGVAGIIKMVMAMRHEQLPRTLHVDRPSTVVDWDAGAVRLLTQQQDWAA SDHPRRAAVSSFGISGTNAHVILEQAPEVEASQSEETRTVVPIALSGRSAAAVRGQAARL RAWLAEQEDVGVAEVARSVAATRASLEHRAVVVAGTVAELADGLDAVATGETAGDQVVDG KLAFLFSGQGAQRVGMGRELADTYPVFAEAFAEVCAAIDQHTEVPLRDVVFGTTALADRG LLDQTQYTQTGLFAVEVALFRLAESWGIVPDALAGHSIGELAAAHVAGVLSLDDAAQLVA ARGRLMGALAEQRGAMVAFAAPEETVRGLLTGHDDVSIAAVNGPAAVVVSGDADMVAEIE RAAGDIQTRRLRVSHAFHSPLMDPMLDEFAAIAAGLTYAAPRIPIVSTVTGRLATAEELR SSEYWVTHVRETVRFGAAVEALVSSGVRTFLELGPDSVLSVLGPQNTDEAAFVPFGRRGQ DEVRTALAAVGRLHARGAAKLGPLLGDGPVRLDLPTYAFQHKRYWLDAAPSGDVTAVGQQ ALAHPMLGAVVPLSGSDTTVLTGRLSAGSVPWLADHVVKGAILVPGTGLLELAVTAGDQV GHPVVEELTLQAPLVLPPDGAVSLQVVVGPAADDRRPVTVFSRPADTDGEWTQHALGTLS AVTRPEPAGLTEWPPPGASVIPVEGAYELLADRGYGYGPAFQGLKAAWRRGNEVFAEVAL PEPAAATAGAYGLHPALLDTAMHADLLGDPSGSTLLPFVWNGVTLHAVGAAVLRVRIVRL DGDELSAIEVADSEGRPVASIESLVSRPVQKELSAAPDTVDGSLLKIAWQPVTAPASDIS VVAVGRGRVGVAATYAGFADLIGAVDRGEPVPELVTLSVPEREGTVPEVSREHAAWLLAE IQAWLTESRFAGTKLAVVTHSATAAGGSTVDVTEGALWGLARGAQAEHPGRVFLVDADTA TTPADIASAVASGEPESAVRAGAVLVPRYTRTETTGVSPFGAGTVLVTGGTGGLGSLLAR YLVAEHGVRDLVLTSRRGLDAPGAAQLADDLTDLGATVTVAACDVADRAAVAELLDALPR LSAVVHAAGTADSGVFDSLTAEQLHSVLKPKVDAAWHLHELTEDRGLSAFVLFSSAGGQV LPAGQANYAAANAFLDGLAQFRRATGRPATALAWGLWAENTGLGGELAEADLARMARLGL PAVTAEQGLALFDAAVATEDAVVAPLRVDIAALKARADELPALLRGFVPPKARRVAKAKA ASADNALANELAALVESERDRVLLDLVRTQVATVLGYADKSEVDGTRAFKELGFDSLAAV ELRNLLGTATGLSLPATLIFDHPTAKAVADFVKGKLLGAATKTPATTTRTNASMQEPIAI VGMACRYPGGVRSPEDLWRLLVDEVDAVSGFPTNRGWDTEGIYDPERGKRGKTYANQGGF LHDAAEFDPAFFGIGPREAMAMDPQQRLLLEAAWEAIERAGIDPTSLRGSLTGVFTGAMY DDYGSRAPGAPADVAAYIPNGSSGAVVSGRISYLLGLEGPCMTVDTACSSSLVTLHLAVQ ALRAGECGLALAGGVTVLSQSDLFVDSSRQGVLSPNGRSKSFSAASDGVGWAEGAGLLLL ERLSDAQRNGHEVLAVVRSSAVNQDGASNGLTAPNGPSQERVIHAALAAGGLRPSEVDAV EAHGSGTKLGDPIEAQALLATYGQDRPEGQPLYLGSVKSNIGHAQASGGAAGVMKVVQAL RHNLLPKTMHVDAPSPVVDWTTGDIELLTEARPWLPNGRPRRAGVSSFGISGTNAHIIIE EAPPSTVEAPRASAPALPVVPLALAGSVGQALADQAARLAEHLRANPELDLTDVGYSLAT GRAALDHRAVVLAADREAALKALDGLATGGTPAGTVTGTISAADLTAFLFTGQGAQQPGM GRELYEAFPVFAGAFDEICGLFATEVPLKQVIWAEKGSPDGALLNQTAYTQCALFAIEVA LFRLVESWGVTPDFVAGHSIGELAAAHAAGVLSLADACTLVAARGRLMQALPSGGAMAAI AATEEEVRAALPSGVDVAAVNGPRSVVISGPETSVQAAMTGFADAGRRTKQLVVSHAFHS ALMEPMLAEFRAVAQGLSYSAPAIPVVSNVTGTIATAAELCSPEYWVGHVREAVRFADGV TTLLGAGVTRFVELGPDAVLTGMARESDTAAAERPDRVVQVPALRRGRDEVTTLFTALGT LFSRGATLDWRALFAGRGASTVDLPTYAFQNKSYWLDATKGSGDVGSLGAKSAKHPLLGA LVELPDGGAVLTGRLSTATQPWLADHVVMGRTMLPGTAYVELAAHAGNQVGAGVLEELTQ QAPLLLPEDGVDLRVVVGAPDTSGRREFSVHSRAEERGAWTQHAAGTLTTTTPAVAFDLA AWPPAGAEAVDLTGLYDDLAGLGFGYGPTFRNLRAVWLHEGEVYAEVALPEGTAAGEFGL HPGLLDSALGATDFLVKGGPKALTETTIPFAWNTVSLFAAGATALRVRVRKTESGAELAL ADTAGAPVAWIESLVTRPVSESQLGAKVPDSLYRVDWQPASGVRLAPSIDGWAVLGADDL GLGLPVHAEPVAADVLVLPVSTEDGDVPARVHATVQKTLALLQNWLGSFDDGKLLVVTRG AVVADTPDLAQAPVWGLVRAAQAENPGRIQLVDVDGKAESAQALPAVAASGEPEAVVRAG EVRVPRLARVTEVGEPIEWTPDGTVLITGGAGLLGSLLARHLVARGARDLVLTSRRGLDA PGARELVDELAGQGAKVTVAACDVTDRGELAGLLDMLPRLTAVVHAAGQMDSAVFGALTP EQVETVLRPKVDAAWNLHELTASRKLSAFVLYSSAGGLLLAAGQANYASGNVFLDALAEH RAAQGLPATSLAWGPWEGTDGEVDLAHIARYGVAELTAEAGLALFDAALAARLPALVPVE LADLKAADRVAPLLRGLVGAPTRRTATAAVTAAPEAGFSDQVAALPAAERETAALQLVCE HAAAVLGYDDASAVGLEKGFTDLGIDSLAALELRNRLGAATGLRLPATLIFDYPSPLPLA RHLLAELLPETEETVVEENDEAAASVAAMDLADLVRSAMGGDQTDERGESR NT seq 15816 nt NT seq  +upstreamnt  +downstreamnt atgtctgagtgggacaagaatccggaatccggcttcgcggagcggctgacgcaagtgccg ccgggcgatcgggcggcgttcgtcgcggacgtggtgcacggcgccacgcgggccgcgctg cgggcggtgctgccggaggtgccggccgtcctcgaccccgagaaggcgttctccgaccac gggttcgactcgctggcggcggtggagctgcacgcgcagctcaccgacgccaccgggttc gacctgccggtgacgctcgcgttcgaccacccgacgccggtcgcggtcgcgcggttcctg ctcgcgcgggtgttcggcgaggagaccgtcgacagtggactcatcgccagtggccgcgac gacgacgagccggtggccatcgtcggcatcggctgccgttatcccggtggcgccgcttcg ccggagcagctgtggcagctggtcgccgacgaggtgcacacgatcagcggcttcccgacc gaccgcgggtgggacctcgacagcctgtacgaccctgaccccgaccggcccggcagcagc tacgtcgcggccgggggcttcctgcccgacgccggcgagttcgacgccggcttcttcggc atcgcgccgcgcgaggcctcggcgatggacccgcagcagcggctcgtgctcgagaccgcg tgggaagcgctggagcgcgcgaagatcgacccgaccacgctgcgcggcacgcccgccggc gtgttcatcggcgccgaggcccaggagtacggcccgcgcctgcacgaagctcccgacggc ctcgacgggtacctgctcaccggcaacgcgccgagcgtcgtctccggccgcgtcgcctac tcgctgggcctcgaaggccccacgctcaccgtcgacaccgcgtgctcgggttcgctggtc gcgctgcacctcgccgtgcaggccctgcgccgcggcgagacgcacctcgcgctcgccggc ggtgtcgccgtgatgggcgcgccgggcacgttcaccgccttcagccgccagcgtggtctg gccgaggacgggcgctgcaaggcgttcgccgcggcggccgacggcaccgggttcgccgag ggtgtcggcgtgctggtgctcgaacggctttccgacgctgtggcgaacgggcacaccgtg ctcgccgtggtccgcggctcggcgatcaactccgacggcgcgtccaacgggctcaccgcg cccaacggcccttcacagcagcgcgtgatcacgcgcgcgctcgccgacgccggcctcgct ccgtccgaagtggacgcggtcgaggcccacggcaccggcacgcggctcggcgacccgatc gaggcgcaggcgctgctcgccacctacgggcgcgaccgtgagacgccgctgtggctgggt tcgctcaagtccaacatcggccacacgcaggccgcggcgggggtcgcgggcgtgatcaag atggtcgaggcgatgcgccgcggtgtgctgccgaagacgctgcacgtcgacgcgccgacc ccgcacgtcgactggaccgcgggatcggtcgagctgctcaccgaggcccgcgagtggccg tcggtcgagcggccgcgccgggccggcgtgtcgtcgttcggtgtgagcggcaccaacgcg cacgtgatcatcgagcaggcgcccgccgtcgaggccgaaggtgagccggctgagctgccg gtggtgccgctgctcgtgtccgctcgggacgaggaggcgctgcgcgcgcaggccgcgaag ctggcgtccattgtagacactgtggacaccgtggacctcgcgagcatcggcttctccctc gccaccacccgcgcggctcacgacttccgcgccgtggtcgtcgccgagaacaccgccgac gctgtccgggggctccaagcgctggctgccggtgagcaggacgccgccgtggtcaccggc gagcgcacgcccggcaagctcgcgatgctgttcaccggccagggttcgcagcggctcgcc atgggccgtgagctctacctcgcctaccccgtgttcgccgaggtcttcgacgaggcgctc gacaacctcgacgtgcagatggaccagccgctgcgcgacgtgctcttcggcgacgacccg gaggagctcaaccacacgcggtacgcgcagtgcgccctgttcgcggtggaggtcgcgctc gcgcggctgctcgaatcgtggggcgtgcggccggacatcctgctcggccactcgatcggt gagctggcggccgcacacctcgccggcgtctggtcgctgaccgacgcgtgcatggtcgtg gccgcgcgcggccgcctgatgcaggcgctgcccgagggcggggcgatggtcgcgttggcc gcgaccgaggacgaagtgcagccgctgctcaacgaccgcgtgagcatcgccgccgtcaac ggcccgtcgtccgtggtcgtctccggtgagcgtgacgccgtcgaggacgtggccaccgtg ttccgcttgcagggccgcaagacgagtgagctgcgcgtgtcgcacgcgttccactcgccg ctgatggagccgatgctggccgagttccgcgagatcctcgaggtcgtggactacgcgccg ccgacgatcccggtggtgtccaacgtgaccggccggctcgccaccgcggaagaactgtgc tcgccgggctactggctctggcacgtgcgccgcgccgtgcggttcgccgacggggtgtcg acgctggccgaggccggcgtcacgaccgcgatcgaggtcggccccgacgccgtgctctcg gcgatggccgccaccggcccgcacgccgagacgatcaccttcaccgccgcgcagcgccgc gaccacgccgaggtgaccacgctggccggcgcgctcggcaagctgcacacgcgcggtgtg gcggtggactggccggcgttcttcggcccggcccgccgggtcgatctgccgacgtacgcc ttccagcgcaagcacttctggctcaccgccccggtttcccacggcgacgcggccgacctc ggccagctcgcctcgagccacccgctgctggccgccgagatcggcctcgcgggcgacggg ctcgtgttcaccggtcgcgtcggcctgcgcacgcacgcgtggctggccgaccacaccatc gcgggcacggcggtgctgccgggtacggcgttcgtcgagatggcgctgcacgccggtgag caggccggttgtggtgtgctcgacgagctgacgctgcaggcgccgctcgcgctgccggag accggtggggtcgcgctgcaggtggtggtgggtccggaggacgacggccgtcgcagcatc gagttccactcccgcgccgaccacgacgccgacgccgcctggacgcgccacgccgtgggc gtgctcgcgaccggtccggtcgtcgagcccgcttcgctgaccgagtggccgcctgccggc gccgaggtcgtcgccacccacgagctgtacggcgagctggccgagcagggttacggctac gggccgctgttccagggcctgcgcacggcgtggcgccgcgacgacgtggtgtacgccgag gtcgcgctgcctgccgagactgacaccgcgttcgggatccacccggcgctgctcgacgcc gtgttgcacgccaccgacttcgcgcccggtgaagcgcgcgaggccgacgagatccggctg ccgttcgcgtggaccggcgtgcggctgcacgcgtcgggcgccaccgaggtgcgggtgcgc atcacctccccggccaccggcggggtgacgctggagatcaccgacccggccggtgcgccg gtgctgtcggtcgagtcgttccgctcccgcgcggtccgcggcgccgacctcggcacgcag gcgcgcgatctgctctacaccgtggaatggacgccggtcaccgccgacgccgagctgccc gccctcgccgccctcggctcggtcgccgggttcgacgtgccggtggccgacgcgctggtg tcgctggtcgacgtgccgccagtggtgctgctgccggtttccgtgcgcggcaagaacgtg gccaccgctgccaagcaggccacgcaccgcgtgctcgccgtgctgcggcagtggctggag aacgagcggtacgagtcggcgcgcctggtcgtgctgacccgcggtgagctggccgactcc gccgtgcgcggcctggtgcgctcggcgcaggccgagcacccgggccgggtcgtgctgatc gaaggcgcggtcacgccggccacgctggccaccgcgctcggctcgggtgagccggagctg cgcgtcgacgggtccgcggtgcacgcggcccgcctggtgcgcctcaccgcggacgccgag cagccggcctggccggccgagggcaccgtgctcatcaccgggggtaccggtggcctgggc gcgcaggtcgcgcgccacgtggtgaccaaccacggcgtgcgcagcctcctgctggtcagc cgtcgcggtgccgacgcgccgggtgcggccgagctggtcgcggacctgacggagctgggc gcgagcgtgaccgtggctgcggccgacgtgagcaagaagcgttcgctggccgccgctctg aagaaggccgagcacccgctgtcggctgtggtgcacaccgccggtgtgctggacaacgcc atgatcggctcgctgaccgaagaccggctcgacgccgtgctggcgccgaaggtcgacgcc gcctggcacctgcacgaactggtcggcgaggtcgacgcgttcgtgctgttctcctcctcc gcgggtctcgctgacggcgcgggccaggcgaactacgcggccggcaacacgttcctcgac gcgttggccgagcaccgctgcaccgaaggcaagacggccacctcgctcgcgtggggtctg tgggacaccgaagccggcatgggtgccactttgtccgaagtggaccgcagccgcatcacc cggctcggtctcgcgccgctgaccgtcgccgaaagcctggccgcactcgacgccgcgctg gcgtccggcgcaccagccgtggtgccgacgcgcgtcgaccggtccgcgctgcgggcgcgg ggcgaagacgtgccggccgtgctgcgcggtctcgcgccggccggtcgtcgccgggccgcc gccgcggtcgcgacgggggagctcacgcccgagcagcagttcgcgggccgcttcgcgcac ctcggtgaggccgaccgcgaccgcgcggtgctcgacttggtgcgcacgcacgtcgcggcc gtgctcggccacgacagcgccgaggccatcaacccggcccgcccgttcggcgagatcggg ttcgactcgctggccgcggtggagctgcgcaacatcctcgactccgtcaccggcatgcgg ctgcccgccacgctcgtgttcgactacccgacaccgcgcgcgctggccgagtacctcgtg ggccggctggcgggcctcgcgccggcgcagccgatcgcgccggtgaccacggccgacccg gaggaaccgatcgccatcgtcggcatcgcctgccggtatccgggtggcgtgaccacgccg gaagacctgtggcggctggtcgccgagggcgaggaggcgctcaccacgttcccggccgac cgcggctggaacgtcgacgcgctgtacgaccccgagcccggcaagcccggccactcctac gtgaagcacggcgccttcctgcacgacgccgcagagttcgacgccgacttcttcgagatc agcccgcgtgaggccgccgccatggacccgcagcagcggctgctgctggaggtctcgtgg gaggcgttcgagcgcgccggcatcgacccggtttcgttgcgcggcagcgccaccggggtg ttcgccggcgtgatgtaccacgactggggcacccgcctcggcacggtctccgacgacatc gccgggtacctcggcaacggcagcctcgccagcgtcgtctccggccgcgtgtcctacgcg ctgggcctggaaggcccgacggtcacggtcgacaccgcgtgctcgtcgtcgctggtcgcg ctgcactgggccgtgcaggcgctgcgtcgcggcgagtgcacgctcgccctcgccggcggt gtcacggtgatgtccactccggacaccttcgtcgacttctcccgccagcgcggcctttct gccgacggccgctgccgttcgttcgccgacgcggccgacggcaccggctggggcgagggc gcgggcatgctgctcgtcgagcggctgtccgacgcgcgccgcaacggtcacccggtcctc gcgctgctgcgcggctccgcggtgaatcacgacggtgcgtccaacggcctcaccgcgccc aacggtccctcgcagcagcgcgtgatcgcgaaggcactggccgacgccggtctcgcaccg tccgaagtggacgcggtcgagggccacggcacgggcaccacgttgggcgacccgatcgag gcccaggcactgctggcgacgtacggccaggagcgcgaagagccgctgtggctcgggtcg atcaagtccaacatcggccacacccaggccgcggccggcgtcgcgggcatcatcaagatg gtgatggccatgcggcacgaacagctgccgcgcacgctgcacgtcgaccggccgtccacg gtggtcgactgggacgccggtgcggtgcggctgctcacgcagcagcaggactgggccgcg agcgatcacccgcgtcgtgcggccgtgtcgtcgttcggcatcagcggcaccaacgcccac gtgatcctggagcaggcgcccgaggtcgaggcgtcgcagtccgaagagacccggaccgtg gtgccgatcgcgctgtcgggccgctcggccgcggcggtgcggggtcaggccgcgaggctg cgcgcctggctggcggagcaggaggacgtcggtgtcgccgaggtcgcgcgttcggtcgcc gcgacgcgggcttccctggagcaccgcgcggtggtcgtcgccgggaccgtggccgagctg gccgacgggctcgacgccgtggccaccggcgagaccgcgggcgaccaggtcgtggacggg aagctcgccttcctgttctccggccagggcgcgcagcgcgtgggcatgggccgcgagctg gccgacacctacccggtgttcgccgaagcgttcgcggaagtctgcgcggccatcgaccag cacaccgaagtgccgctgcgggacgtcgtgttcggcacgaccgcgctcgccgatcgcgga cttctcgaccagacgcagtacacgcagaccggcctcttcgccgtggaggtggcgctcttc cgcctcgccgagtcgtgggggatcgtgcccgacgcgctggccggccactcgatcggcgag ctggccgccgcgcacgtcgccggggtgctgtcactcgacgacgccgcgcagctggtcgcc gcgcgcggccgtctgatgggcgcgctggccgagcagcggggcgcgatggtcgcgttcgcc gcgccggaggagaccgtgcgcgggctcctgaccggccacgacgacgtgagcatcgccgcc gtgaacgggcccgccgccgtggtggtctcgggtgacgccgacatggtcgcggagatcgag cgcgcggccggggacatccagacgcgccggttgcgcgtgagccacgcgttccactcgccg ctgatggacccgatgctcgacgagttcgccgcgatcgccgccggtctcacctacgcggcg ccgcggatcccgatcgtctccaccgtgaccggccgcctggccaccgccgaggagctgcgt tcgtccgagtactgggtcacacacgtccgcgagaccgtgcgcttcggcgcggccgtcgaa gcgctggtgtcgagcggggtgcggacgttcctcgagctcgggcccgacagtgtcttgtcg gtgctcggcccgcagaacaccgacgaggccgcgttcgtgccgttcggccgccggggccag gacgaggttcgcacggcgctggccgccgtcggccgcctgcacgcccgtggcgcggccaag ctcgggccgctgctcggcgacggcccggtccggctcgacctgccgacgtatgccttccag cacaagcgttactggctcgacgccgcgccgtccggtgacgtcacggccgtgggccagcag gcgctggcgcacccgatgctcggtgcggtcgtgccgctgtccggctcggacaccacggtg ctcaccggccggctctcggccggatcggtgccgtggctggccgaccacgtggtgaagggc gcgatcctcgtgcccggcaccggtctgctggagctggccgtgacggccggcgaccaggtg ggccacccggtggtggaggagctgacgctgcaggcgccgctcgtcctgccgcccgacggc gcggtgtcgctgcaggtcgtggtcggccccgccgccgacgaccgccgcccggtgacggtg ttctcgcgcccggccgacaccgacggcgagtggacgcagcacgcgctcggcacactgtcg gccgtcacgcggcccgagcccgccgggctcaccgagtggccgccgccgggcgcgagcgtg atccccgtcgagggtgcctacgagctgctcgccgaccgcggttacggttacggcccggcg ttccagggcctcaaggcggcgtggcgccgcggcaacgaggtgttcgccgaggtcgcgctg ccggaaccggccgccgccacggccggcgcctacggcttgcacccggcactgctcgacaca gccatgcacgccgacctgctcggcgacccgagcggctcgacgctgctgccgttcgtgtgg aacggcgtgacgctgcacgcggtcggcgccgccgtgctgcgggtgcgcatcgtgcgcctc gacggtgacgagctctcggccatcgaggtagccgacagcgaaggccgcccggtcgcgtcg atcgaatcgctcgtgtcgcggcccgtgcagaaggagctctcggccgcaccggacacagtg gacggttcgctgctcaagatcgcgtggcagccggtcaccgcgccggcttccgacatcagt gtggtggctgtgggccgcggccgggtcggcgtggccgccacctacgccgggttcgcggat ctgatcggggccgtcgaccgcggtgagccggtgccggagctggtgaccctgtcggtgccc gaacgcgaaggtacggtgccggaggtttcgcgcgagcacgccgcctggctgctggccgag atccaggcctggctgacggaatcacggttcgcgggtacgaagctcgcggtcgtcacgcac tccgcgacggcggccggtgggtccactgtggacgtgaccgaaggtgcgctctggggtctg gctcggggagcccaggccgaacacccgggccgcgtcttcctcgtggacgccgacaccgcc acaacgccggcggacatcgcctcagcggtggcctccggcgagccggagtccgcggtgcgc gccggcgcggtgctcgtgccgcggtacacgcggaccgagaccaccggggtgtcgccgttc ggtgcgggaacggtgctggtcaccggcggtaccggcgggctcggcagcctgctggcgcgc tacctcgtggccgaacacggcgtgcgggacctggtgctcacgagccgccggggcctcgac gcgccgggtgcggcgcagctggccgacgacctcaccgacctcggtgccacggtcacggtc gcggcgtgcgacgtcgccgaccgggccgccgtggccgaactgctcgacgcgttgccgcgg ctgtcggccgtggtccacgcggcgggcacggccgacagcggcgtcttcgactcgctcacc gccgagcagctgcactccgtgctcaagcccaaggtcgacgccgcctggcacctgcacgag ctcacggaggaccgcgggctgtccgcgttcgtgctgttctcctccgccggcggccaggtg ctgcccgcgggccaggcgaactacgccgccgccaatgcgttcctcgacggtctcgcccag ttccgccgggcgacgggccggcccgccaccgcgctggcgtggggcctgtgggccgagaac accgggctcggtggcgagctcgccgaggccgacctcgcccgcatggctcgcctcggcctg ccggcggtcaccgccgagcagggcctcgcgctgttcgacgccgcggtggccacggaagac gccgtggtggcgccgctgcgcgtggacattgcggctctgaaggcccgcgcggacgagctg ccggctctcctgcgtggcttcgtgccgccgaaggcccggcgcgtggcgaaggccaaggcc gcgagcgcggacaacgcgctggccaacgagctggccgccctcgtcgagagcgagcgcgac cgcgtgctgctggacctcgtgcgcacgcaggtggctaccgtgctcggctacgcggacaag tccgaagtggacggcacgcgagcgttcaaggaactcgggttcgactccctggccgccgtc gagctgcgcaacctgctcggcaccgccacgggtctgtcgttgccggcgacgctcatcttc gaccacccgaccgccaaggccgtcgccgatttcgtgaagggcaagctgctcggcgccgcc acgaagacccccgcgacgacgacccggaccaacgcgtccatgcaggaacccatcgccatc gtcggcatggcgtgccgttaccccggtggcgtgcgctcgccggaggacctctggcggctg ctcgtggacgaggtcgacgccgtcagcggcttcccgaccaaccgcggctgggacaccgag ggcatctacgaccccgaacgcggcaagcgcggcaagacgtatgccaaccagggtggtttc ctgcacgacgccgccgagttcgacccggcgttcttcggcatcggcccgcgtgaggccatg gcgatggacccgcagcagcgcctgctgctggaagcggcgtgggaggccatcgaacgcgcc ggcatcgacccgacgtcgttgcgcggcagcctgaccggcgtgttcaccggcgccatgtac gacgactacggctcccgcgcccccggtgcgcccgccgacgtcgccgcctacatccccaac ggcagctccggcgcggtcgtctccggccgcatctcctacctgctcggcctcgaaggcccg tgcatgaccgtggacacggcgtgctcgtcttcgctggtcacgctgcacctcgcggtgcag gcgctgcgggccggggagtgcgggctggccctggccggcggggtcacggtgctctcgcag tcggacctgttcgtggactccagccgccagggcgtgctttcgcccaacggccgctcgaag tcgttctcggccgcctccgacggcgtcggctgggccgagggcgcgggcctgctgctgctg gaacgcctgtccgacgcccagcgcaacggccacgaggtgctcgccgtggtccgctcgagc gcggtgaaccaggacggcgcgtccaacggcctcaccgccccgaacggtccctcacaggaa cgcgtgatccacgcggcgctcgccgccggtggcctgcgaccgtccgaagtggacgccgtg gaggcgcacggttcgggcacgaagctcggcgacccgatcgaggcgcaggcgctgctggcc acctacggccaggaccggcccgaggggcagccgctgtacctgggttcggtgaagtcgaac atcggccacgcgcaggcctccggtggtgcggccggcgtgatgaaggtcgtgcaggcgctg cggcacaacctgttgccgaagaccatgcacgtcgacgcgccgtcgccggtcgtcgactgg acgaccggggacatcgagctgctgaccgaggcccggccgtggctcccgaacgggcgtccg cgccgtgcgggggtctcgtccttcggcatcagcggcaccaacgcgcacatcatcatcgag gaggcgccgccgtccacggtggaggcgccgcgggccagtgctcccgcgttgccggtggtg ccgctggcgctcgcgggttcggtgggccaggcgctggccgaccaggccgcgcggctcgcc gagcacctgcgggcgaacccggagctggacctgaccgacgtcggttactcgctggccacc ggccgcgcggcgctcgaccaccgcgcggtggtgctggctgctgaccgtgaggccgcgctg aaggcgctcgacggactcgccaccggcgggaccccggcgggcaccgtgaccggcacgatc agcgcggccgacctgaccgcgttcctgttcaccggtcagggcgcgcagcagccgggtatg ggccgcgagctctacgaagcgttcccggtcttcgccggcgcgttcgacgagatctgcggt ctcttcgccacggaggtgccgctaaagcaggtgatctgggcggagaagggctcgcccgac ggtgcgctgctcaaccagaccgcctacacgcagtgcgcgctgttcgcgatcgaggtcgcg ctcttccgcctggtcgagtcgtggggtgtcacgcccgacttcgtggccggacactcgatc ggcgagctggccgcggcccacgcggccggggtgctgtcgctggccgacgcgtgcacgctc gtcgccgctcgtggccgcctgatgcaggcgctgccgagcggaggcgcgatggccgcgatc gccgccacggaggaggaagtgcgagccgcgctgccgtccggggtggacgtcgcggcggtc aacgggccgcgctcggtcgtgatctccgggccggagacttcggtgcaggcggccatgacc gggttcgcggacgcaggacgccgcacgaagcagctggtcgtgtcgcacgcgttccactcg gcgctgatggagcccatgctggccgagttccgcgcggtcgcgcagggactcagctactcc gcgccggcgattccggtggtctccaacgtgaccggcacgatcgccactgccgctgagctg tgctcgcccgagtactgggtgggccacgtgcgggaggccgtgcggttcgccgacggtgtc accacgttgctgggcgccggcgtgacgcggttcgtggaactggggccggacgcggtgctc acgggcatggcccgcgagagcgacaccgcggccgccgaacggcccgaccgcgtggtgcag gtgccggccctgcggcgtggccgcgacgaggtgaccacgctgttcaccgcgctcggcacg ctgttctcgcgcggcgcgaccctcgactggcgggcgctgttcgccggccgcggtgcgtcc actgtggacctgccgacgtatgcgttccagaacaagtcgtactggctcgacgcgaccaag ggcagcggtgacgtcggatcgctgggcgcgaagtcggcgaagcacccgctgctgggtgcg ctggtcgagctgccggacggcggtgcggtcctcaccggccgtctgtccaccgcgacgcag ccgtggctggccgaccacgtggtgatgggccgcacgatgctgcccggcaccgcgtacgtc gagctggccgcgcacgccggtaaccaggtcggcgcgggcgtgctggaagagctgacccag caggcaccgctgctgctgcccgaggacggcgtggacctgcgcgtggtcgtcggggcgccg gacacgagtggccgccgggagttctcggtgcactcgcgggccgaagaacgcggcgcctgg acccagcacgcggccggcacgctcaccaccacgaccccggccgtggcgttcgatctggcg gcctggccgccggccggcgccgaggccgtggacctgaccgggctgtacgacgacctcgcg ggcctgggcttcgggtacggcccgacgttccggaacctgcgcgcggtctggctgcacgaa ggggaggtgtacgccgaggtcgcgctgcccgagggcacggcggccggtgagttcggcctg cacccggggctgctcgactccgcgctcggcgccacggacttcctcgtgaagggcggtccg aaggcgctgaccgagaccacgatcccgttcgcgtggaacacggtgtcgctcttcgcggcc ggggccacggcgctgcgggtgcgggtgcgcaagaccgagagcggcgcggagctggcgctc gccgacacggccggtgcgccggtcgcgtggatcgagtcgctggtcacgcggccggtgtcg gagagccagctcggcgcgaaggtgccggactcgctctaccgcgtcgactggcagcccgcc tcaggggtacggctggcgccgtcgatcgacggctgggccgtgctcggggccgacgacctc ggtctcgggttgccggtgcacgccgagccggtggcggccgacgtgctggtactgcccgtc tcgaccgaggacggcgacgtgccggcccgcgtccacgcgaccgtgcagaaaacgttggcg ctgctgcagaactggctcggctcgttcgacgacggcaagctcctggtggtcacccgcggt gcggtcgtggccgacacgccggacctggcgcaggcgccggtgtggggcctggtgcgggcc gcgcaggcggagaaccctggccggatccagctggtcgacgtcgacggcaaggccgagtcg gcacaggcactgccggcggtggcggcttcgggtgagcccgaggcggtcgtccgggccggt gaggtgcgcgtgccgcggctggcccgcgtgacggaggtcggcgaaccgatcgagtggact ccggacggcacggtgctcatcaccggtggcgccggcctgctcgggagcctgctggcccgg cacctggtcgctcgtggtgcccgggacctcgtgctcacgagccgccgcggcctcgacgcg ccgggtgctcgggagctggtcgacgagctcgccggacaaggcgcgaaggtgaccgtggcc gcgtgcgacgtcaccgaccgcggcgaactcgcggggctgctcgacatgttgccgcggctc accgccgtggtgcacgcggccgggcagatggacagcgcggtgttcggcgcactcactccg gagcaggtcgagaccgtgctgcggccgaaggtcgacgcggcctggaatctgcacgagctc accgcgtcacgaaagctgagcgcgttcgtcctctactcgtcggcaggcggcctgttgctc gccgcggggcaggccaactacgcgtcgggcaacgtgttcctcgacgcgctggccgagcac cgggcggcacagggcctgccggcgacttcactggcctggggtccgtgggaagggaccgac ggcgaggtcgacctggcgcacatcgcccggtacggcgtcgcggaactgaccgcggaagcc gggctcgcgttgttcgacgcggcgctcgcggcccggttgccggccctggtgccggtggag ctggccgacctcaaggccgccgaccgcgtggcaccgctgctgcggggcctggtcggcgcg ccgaccaggcgcacggcgacggccgcggtcactgccgcgcctgaagccggtttctcggac caggtcgccgcgctgccggcggccgagcgggaaacggcggcgctgcagctggtgtgcgag cacgcggcggcggtgctgggttacgacgacgcttcggcggtcggcctggagaagggcttc accgacctcggcatcgactcgctggctgcgctggagctgcgcaaccggctcggcgcggcc accgggctgcggctgccggcgacgctgatcttcgactacccgagcccgttgccgctggcc cgccacctgctggcggagctgctgccggagaccgaagagaccgtggtcgaggaaaacgac gaagccgcggcgtccgtcgcggcgatggacctggccgacctggtccgctccgccatgggc ggcgaccagaccgacgaacgaggtgagtcccggtga

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