Amycolatopsis rhabdoformis: VSH64_36220
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Entry
VSH64_36220 CDS
T09694
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
arhd
Amycolatopsis rhabdoformis
Pathway
arhd00280
Valine, leucine and isoleucine degradation
arhd00640
Propanoate metabolism
arhd00785
Lipoic acid metabolism
arhd01100
Metabolic pathways
arhd01110
Biosynthesis of secondary metabolites
arhd01210
2-Oxocarboxylic acid metabolism
Module
arhd_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
arhd00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
VSH64_36220 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
VSH64_36220 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
VSH64_36220 (pdhA)
Enzymes [BR:
arhd01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
VSH64_36220 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
WSE28246
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Position
7856718..7857923
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AA seq
401 aa
AA seq
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MPSEQWTHPEPGDGPAAVAAKPSPEQVIAGLRATSEGGAELTQLLTPEGQRIPSPQFDKY
VADVDDEVLRNLYRDMVLVRRADREANAMQRQGQLGIWVPLLGQEAAQIGSGRALKPTDM
AFPSYREHGVAYARGVDLRELLGIFRCTDHSGWDYKAHGFHPYTIVIGNQVLNAAGYAMG
QKFEGKVGDDDGEATICYFGDGATSQGDVHEGFVWAAVYDAPLVFFCQNNQWAISEPTER
QSRLPLYQRARGYGFPGIRVDGNDVLACLAVTRWALEECRHGNGPVLIEAFTYRMDAHTT
TDDPTRYRLSDELEEWKLKDPIERVRAYLARGGGADHDFFDQVQAEADEFAKQLRDYTFN
MPEPPPERIFANVYAEPSPALEAQQKEFLSYLDGFATAGEH
NT seq
1206 nt
NT seq
+upstream
nt +downstream
nt
atgccgtccgaacagtggacgcaccccgagcctggcgacgggccggccgccgtagcggcc
aagccctcacccgaacaggtgatcgcgggtctgcgagcaacgagtgaaggtggcgctgag
ctcactcagctgctcacccccgaaggtcagcgaatcccgtcgccgcagttcgacaagtac
gtggcggacgtggacgacgaggtgctccgcaacctctaccgcgacatggtgctggtgcgc
cgcgccgaccgcgaggccaacgcgatgcagcgccaggggcagctgggcatctgggtaccg
ctgctgggccaggaggccgcgcagatcggctccggccgcgcgctgaagcccaccgacatg
gcgttcccgagctaccgcgagcacggcgtcgcgtacgcgcgcggcgtggacctgcgtgag
ctgctcggcatcttccggtgcacggaccacagcggctgggactacaaggcccacggcttc
cacccctacaccatcgtgatcggcaaccaggtgctcaacgccgccggttacgccatgggg
cagaagttcgagggcaaggtcggcgacgacgacggcgaagccaccatctgctacttcggc
gacggcgccacttcgcagggcgacgtgcacgaaggcttcgtctgggccgccgtctacgac
gcgccgctcgtcttcttctgccagaacaaccagtgggccatctccgagcccaccgaacgc
cagtcgcgcctgccgctctaccagcgcgcccgcggctacggcttccccggcatccgcgtg
gacggcaacgacgtgctcgcctgcctcgccgtcacccgctgggcgctcgaggagtgccgg
cacggcaacggcccggtgctgatcgaggccttcacctaccggatggacgcccacaccacc
accgacgaccccacccgctaccggctctccgacgagctggaggagtggaagctcaaggac
ccgatcgagcgcgtgcgcgcctacctcgcacgcggcggcggcgcggaccacgacttcttc
gaccaggtgcaggccgaagccgacgagttcgcgaagcagcttcgcgactacacgttcaac
atgccggagccgccgcccgagcggatcttcgccaacgtctacgcggagccctcgccggct
ctcgaggcgcagcagaaagagttcctgtcctatttggacggcttcgcgacggcgggtgag
cactga
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