Amycolatopsis roodepoortensis: NQK81_35935
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Entry
NQK81_35935 CDS
T08507
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
aroo
Amycolatopsis roodepoortensis
Pathway
aroo00290
Valine, leucine and isoleucine biosynthesis
aroo00660
C5-Branched dibasic acid metabolism
aroo01100
Metabolic pathways
aroo01110
Biosynthesis of secondary metabolites
aroo01210
2-Oxocarboxylic acid metabolism
aroo01230
Biosynthesis of amino acids
Module
aroo_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
aroo00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NQK81_35935 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NQK81_35935 (leuC)
Enzymes [BR:
aroo01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NQK81_35935 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
NQK81_35935 (leuC)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
UUV30111
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All DBs
Position
7464013..7465431
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AA seq
472 aa
AA seq
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MPRTLAEKVWESHLVRRGEGAEPDLLYIDLHLLHEVTSPQAFDGLRLAGRKLRRPDLTIA
TEDHNVPTIDIELPIADPVSRTQVDTLRANCKEFGVRLHPMGDAEQGIVHVIGPQLGLTQ
PGMTVVCGDSHTSTHGAFGAMAFGIGTSEVEHVMATQTLPLRPFKTMAITVDGELRPGVT
AKDVILAVIAKIGTGGGQGYVLEYRGEAIEKLSMEARMTVCNMSIEAGARAGLIAPDETT
FEYLKGRPHAPQGADWDAAVENWRELRTDDDAVFDAEVRLNADELTPFVTWGTNPGQGLP
LGAEVPDPERIGDENERIAAEKALSYMDLKPGTPLREIAVDTVFLGSCTNGRIEDLRAAA
DVLRGHKVADSVRMLVVPGSMRVRQAAEAEGLDRVFTEAGAEWRQAGCSMCLGMNPDQLK
PGERSASTSNRNFEGRQGKGGRTHLVSPLVAAATAVRGTLSSPEDLQPAVAR
NT seq
1419 nt
NT seq
+upstream
nt +downstream
nt
atgccccggacactggccgagaaagtgtgggagtcgcacctggtgcggcgcggcgagggg
gccgagcccgacctgctctacatcgatctccacctgctgcacgaggtcaccagccctcag
gcgttcgacggactccgcctggcgggccggaaactgcgccgccccgacctcaccatcgcg
accgaggaccacaacgtcccgacgatcgacatcgagctgccgatcgcggatcccgtgtcc
cgcacccaggtcgacacccttcgcgccaactgcaaggagttcggcgtccggctgcacccg
atgggcgacgccgagcagggcatcgtgcacgtcatcggcccgcagctgggcctgacccag
ccggggatgaccgtggtgtgcggcgacagtcacacctcgacgcacggtgccttcggtgcc
atggcgttcggcatcggcacctccgaggtcgaacacgtgatggccacgcagaccctgccg
ctccgtccattcaagacgatggcgatcacggtcgatggcgaactgcgccccggcgtcacg
gcgaaggacgtcatcctcgcggtgatcgcgaagatcggcaccggcggcggtcagggctac
gtcctcgagtaccgcggcgaggccatcgaaaagctgtcgatggaagcccggatgacggtg
tgcaacatgtccatcgaagccggcgcgcgcgccgggctcatcgcgccggacgagacgacg
ttcgagtatctgaagggccgcccgcacgccccgcagggcgccgattgggacgccgccgtc
gagaactggcgcgaactccgcaccgacgacgacgccgtcttcgacgccgaggtgcgcctg
aacgccgacgagctcacgcctttcgtgacctggggcacgaacccgggccaggggctcccg
ctgggcgccgaggtgcccgacccggagcgcatcggcgacgagaacgagcgcatcgccgct
gagaaggccctgtcctatatggatctgaagccgggcacgccgctgcgcgagatcgcggtg
gacaccgtcttcctcggctcgtgcacgaacggccggatcgaggatctgagggccgccgcg
gacgtcctgcgcgggcacaaggtcgccgactcggtccggatgctcgtcgtccccggctcg
atgcgcgtccgccaggcggcggaagccgaagggctggaccgggtcttcaccgaagcgggc
gcggaatggcgtcaggcgggctgctcgatgtgcctcggcatgaacccggatcagctcaag
ccgggcgagcgcagcgcgtcgacctcgaaccgcaacttcgaaggcaggcagggcaagggc
ggccggacgcatctggtctcgccgctcgtggcggccgccacggccgtgcggggcacgctg
tccagccccgaagacctgcagcccgccgtcgctcgctga
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