Anguilla rostrata (American eel): 135244609
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Entry
135244609 CDS
T10705
Symbol
gclc
Name
(RefSeq) glutamate--cysteine ligase catalytic subunit
KO
K11204
glutamate--cysteine ligase catalytic subunit [EC:
6.3.2.2
]
Organism
arot Anguilla rostrata (American eel)
Pathway
arot00270
Cysteine and methionine metabolism
arot00480
Glutathione metabolism
arot01100
Metabolic pathways
arot01240
Biosynthesis of cofactors
arot04216
Ferroptosis
Module
arot_M00118
Glutathione biosynthesis, glutamate => glutathione
Brite
KEGG Orthology (KO) [BR:
arot00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
135244609 (gclc)
09106 Metabolism of other amino acids
00480 Glutathione metabolism
135244609 (gclc)
09140 Cellular Processes
09143 Cell growth and death
04216 Ferroptosis
135244609 (gclc)
Enzymes [BR:
arot01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
135244609 (gclc)
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Motif
Pfam:
GCS
GCS2
Motif
Other DBs
NCBI-GeneID:
135244609
NCBI-ProteinID:
XP_064173115
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Position
18:complement(18371009..18389672)
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AA seq
629 aa
AA seq
DB search
MGLLSQGSPLNWEETKKYADHVRKHGIIQFLNIYNKVKDRQKDVLKWGDEVEYMLVAMDE
KDEKARLVLNGAEVLETLQDKGEKTNPNHPTLWRPEYGSYMIEGTPGQPYGGTMSEFNTV
EDNMDKRRKEASSVLKERQTLCTITSFPRLGCPGFTMPEFKPTPVERGASKSLFFPDEAI
NRHPRFSTLTRNIRHRRGEKVVINVPIFKDKNTPSPFVEKFPEDDGEAERGALADHIYMD
AMGFGMGNCCLQVTFQACSINEARYLYDQLATICPIVMALSAASPFYRGHVSDIDCRWGV
ISASVDDRTKEERGVEPLKNNKFRIFKSRYDSIDSYLSPCGEKYNDIELTIDEEINQQLL
DAGIDKPLAQHIAHLFIRDPLSLFEEKIHLDDANESDHFENLQSTNWQTMRFKPPPPNSD
IGWRVEFRPMEVQLTDFENSAYVVFVVLLTRVILSYKLDFLIPLSKVDDNMKMAQKRNAV
LEGMFYFRKDIFKGCSPVLEGSPATPNGLDNDTAEYALMSIDTIINGKEGVFQGLIPILN
CYLENMEVDVDTRCTILNYLKLIKKRASGQLMTMARWMREYVAQHPEYKQDSVITDKINY
DLLVRCDRIAKGELRCPELFGDPVNRRNK
NT seq
1890 nt
NT seq
+upstream
nt +downstream
nt
atgggcttgctgtcacaagggtctcctttgaactgggaagagaccaaaaagtacgcggat
catgttagaaaacatggcatcattcagtttctcaacatctacaacaaggtgaaagaccga
cagaaggacgtgttaaaatggggcgatgaggtggagtacatgctggtagcaatggacgag
aaggatgaaaaggctcgcctggtgttgaatggagccgaggtgctggagacgcttcaggac
aaaggtgaaaaaaccaacccaaaccaccccacgctctggaggccagagtacggcagctac
atgatcgagggcacccccgggcagccctacgggggtaccatgtccgagttcaacacggtg
gaggacaacatggacaagaggaggaaggaggcttcgtccgttctcaaagagcgacagacg
ctctgcacaattacatcattccccaggctgggctgccctggtttcaccatgccggagttc
aagcccactccagtcgaaagaggagcctccaagtctctctttttcccggacgaggctata
aaccggcacccgaggttcagcactctgacacgaaacatccgtcataggaggggggagaag
gtggtgatcaacgtgcccatttttaaggacaagaacaccccgtctccgtttgtggagaaa
ttccccgaagacgacggggaggcggaaaggggggcgcttgctgaccacatctacatggac
gccatggggtttgggatgggtaactgctgcctgcaggtaacgttccaggcttgtagcatt
aatgaggcaagatacctgtatgaccagctggctacaatatgccccattgtgatggccctg
agcgccgcctcgcccttctacaggggccacgtctccgacatcgactgccgctggggggtc
atctccgcctcggtggacgaccggacgaaagaggagaggggtgtggagcccctgaaaaac
aacaagttccgaatctttaaatccagatacgactcaatcgacagctacctgtccccctgc
ggtgagaaatacaatgatatagaactgacgatagacgaggagatcaaccagcagcttctg
gacgcaggaatcgacaaaccgctggcacagcacatagcccacctcttcatccgtgaccct
ctaagcctcttcgaggagaaaatccacctggacgacgcaaacgaatccgaccacttcgag
aacctgcagtccaccaactggcagacaatgcgattcaagccgcctcccccgaactcggac
atcggctggagggtggagtttcgcccaatggaggtccagctgacagactttgagaactct
gcgtatgtggtgtttgtggttctgctcaccagggtaatcctttcctacaagctggacttt
cttatccccctgtcgaaggtcgatgacaacatgaaaatggctcagaagcggaacgcggtt
ctggagggcatgttttacttccggaaggacatcttcaagggctgcagtcccgttctggag
ggatcccccgccactccaaacggactggacaacgacaccgcggagtacgccctgatgagc
atcgacaccatcatcaacggaaaggagggcgtgttccaaggactcattccaatcctcaac
tgttacctggaaaacatggaagtggatgtggacacgcggtgcaccatcctcaactacctg
aagctcatcaaaaaaagggcctcaggtcagctgatgaccatggcccgctggatgagggag
tacgtggcccagcaccccgagtacaagcaggacagcgtgatcaccgacaagatcaactac
gacctgctggtgcgctgcgaccgcatcgccaagggagagctgcgctgccccgagctgttc
ggggaccccgtcaaccgccgcaacaaatga
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