Aeromonas salmonicida subsp. salmonicida A449: ASA_3409
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Entry
ASA_3409 CDS
T00500
Symbol
leuA
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
asa
Aeromonas salmonicida subsp. salmonicida A449
Pathway
asa00290
Valine, leucine and isoleucine biosynthesis
asa00620
Pyruvate metabolism
asa01100
Metabolic pathways
asa01110
Biosynthesis of secondary metabolites
asa01210
2-Oxocarboxylic acid metabolism
asa01230
Biosynthesis of amino acids
Module
asa_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
asa00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ASA_3409 (leuA)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ASA_3409 (leuA)
Enzymes [BR:
asa01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ASA_3409 (leuA)
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Gene cluster
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Trp_syntA
IPMS_D2
NAD_binding_10
Motif
Other DBs
NCBI-ProteinID:
ABO91384
UniProt:
A4SR62
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All DBs
Position
3689551..3691125
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AA seq
524 aa
AA seq
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MSDRVIIFDTTLRDGEQALAASLTVKEKLQIAQALERLGVDIMEVGFPVSSPGDFQSVQT
IARHIKNSRVCALARALPQDIDAAGEALRVAEAFRIHTFISTSSIHVESKLKKSFEDVLE
MGVSAIKHALRYTDDVEFSCEDAGRTPIDNLCRMVEAAIKAGARTINIPDTVGYTVPTEF
SGIIQTLFNRVPNIDKAIISVHCHDDLGLSVANSIGAVQMGARQIECTINGIGERAGNCS
LEEVAMILKTRADLLGVHTNIRHSEIHRTSALVSQLCNMPVQPNKAIVGANAFSHSSGIH
QDGVLKAKNTYEIITPESIGLPQNNLNMTSRSGRHVIKHRMESMGYAESSYDLDHLYGKF
LTLADKKGQVFDYDLEALAFFSQIHEEPEHFKLEYLGVQSGSSVLATASVKLKVGQDLVC
EAATGNGPVDAVYQCINRITGYEIRIDKYALKAKGEGKNALGQVDIVAEYKGRKFHGMGL
ATDIIESSAQALIHVINSIWRADQVAEQMERNVTKTDKINTESV
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
atgtcagatcgggtcatcattttcgacaccaccttgcgcgatggtgagcaggccctggcg
gccagtttgaccgtcaaggagaagctgcagatcgcccaggcgctggagcggctcggcgtc
gacatcatggaagtgggattccctgtctcctcccccggcgattttcaatcggtgcagacc
atagcccgccacatcaagaacagccgggtctgcgccctcgcccgcgccctgccccaggat
atcgacgccgccggtgaagccttgcgggtcgcagaagcttttcgcatccatacctttatc
tccacctcctccattcacgtcgagagcaagctgaaaaagagcttcgaggatgtgctggag
atgggggtcagcgccatcaagcacgccttgcgctacaccgacgatgtagagttctcctgc
gaggatgcgggtcgcaccccgattgataatctctgtcgcatggtggaagcggccatcaag
gccggcgcccgcaccatcaatatcccggataccgtcggctacacggtaccgaccgagttc
tccggtatcatccagaccctgttcaaccgggtgcccaacatcgacaaggccatcatctct
gtgcactgccacgatgacctgggactgtcggtggccaactccatcggcgccgtgcagatg
ggagcccgccagatcgagtgcaccatcaacggcatcggcgagcgggccggcaactgctcc
ctggaagaggtcgcgatgatcctgaaaacccgcgccgacctgcttggggtccataccaac
atccgccacagcgaaattcatcgcaccagcgccctggtcagccagctgtgcaacatgccg
gtgcagccgaacaaggccatcgtcggggccaacgccttctcccacagctcaggcatccat
caggacggcgtgctcaaggcgaagaacacctatgaaatcatcacccccgagagcattggc
ctgccccagaacaacctcaacatgacctcccgctccggccgtcacgtcatcaagcacaga
atggagtccatgggttatgccgagagcagctacgatctcgaccacctctacggcaagttc
ctgaccctggccgacaagaaggggcaagtattcgactacgacctggaggcgctggccttc
ttcagccaaatccacgaagagccggagcacttcaagctggagtacctgggcgtacaaagc
ggcagctctgtgctggccaccgcctcggtcaaattgaaggtcgggcaggatctggtctgc
gaagcggctaccggcaatggtcctgtggatgcggtctaccagtgcatcaaccgcatcacc
ggctacgagatccgcatcgacaaatacgccctcaaagccaagggtgagggcaagaatgcc
ctcggccaggtcgatatcgtcgccgaatacaagggacgaaaattccacggcatgggcctg
gctaccgatatcatagagtcctctgcccaggcgttgatccacgtaatcaacagcatctgg
cgcgccgatcaggtggccgaacagatggaacgcaacgtcacaaaaacagacaagatcaat
acggagagtgtgtga
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