Actinoplanes sp. SE50/110: ACPL_233
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Entry
ACPL_233 CDS
T02044
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K23269
phosphoribosylformylglycinamidine synthase subunit PurL [EC:
6.3.5.3
]
Organism
ase
Actinoplanes sp. SE50/110
Pathway
ase00230
Purine metabolism
ase01100
Metabolic pathways
ase01110
Biosynthesis of secondary metabolites
Module
ase_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ase00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
ACPL_233 (purL)
Enzymes [BR:
ase01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
ACPL_233 (purL)
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Gene cluster
GFIT
Motif
Pfam:
AIRS_C
AIRS
FGAR-AT_linker
DUF2099
Motif
Other DBs
NCBI-ProteinID:
AEV81132
UniProt:
G8S4T5
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Position
127999..130392
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AA seq
797 aa
AA seq
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MTTQDKTGFAATDVLAEGFADGPDTVQKAEQTSDDLQPYAELGLKDDEYAKIKDILGRRP
TASELAMYSIMWSEHCSYKSSKVHLREFVAKVPKNTRMLAGIGENAGVVQVSDDLAVTFK
VESHNHPSYVEPYQGAATGVGGIVRDILAMGARPIAVMDPLRFGAHDHPDTARVLPGVVA
GIGGYGNCLGLPNIGGEIVFDPCYQGNPLVNALSIGVLPVERLQKKEATGTGNIVVLLGA
RTGRDGIGGVSVLASATFDEEAEQRRPSVQVGDPFMEKLLIESCLELYDAGLVTGIQDLG
GAGLTCALTETAAAAGTGMRVWLERVPLREASMSPTEILASESQERMLLIVTPENLDAVL
KVAEKWGVWATAIGEVTPRAEDGTPGRLHITWNDHVVVDVPPGSLADDGPIYERPLREPS
DLILLQADRAETLPRPTTGAELRETVLRMAASPNLCDKTWVTEQYDRYVLGNTVLAQPED
SGVLRLDEQTNLGVALSVDGNGRFARLDPYEGAKLALAEAYRNVAVTGAEPIAVTDCLNF
GSPEDPAVMWQFARAVQGLADGCQQLGTPVTGGNVSFYNQTGAAAIHPTPVVGVMGLFDD
VTRRVPMGFKAAGELLFLLGETREELSGSEWAWVTHGHLGGRPPKVDLAAEQTLGRLMAR
VSQTGLVSAAHDLSDGGLAQVLVESCLRYGTGASVTVESAFVGLFSESAARVLVSVPQGH
EKAFVALAAELGVPCAKIGTTTEAAALEVTGQFTIPLDELRAAWSGTLPKLFGGAEPAAE
GRSVTLELTEPKPGGPL
NT seq
2394 nt
NT seq
+upstream
nt +downstream
nt
gtgaccacgcaggacaagaccggcttcgccgccaccgacgtcctggccgagggcttcgcc
gacggcccggacaccgtgcagaaggccgagcagacctccgacgacctgcagccgtacgcc
gagctcgggctcaaggacgacgagtacgcgaagatcaaggacatcctcggccggcgcccc
accgcgtccgagctggcgatgtactcgatcatgtggagtgagcactgctcgtacaagtcg
agcaaggtgcacctgcgcgagttcgtcgccaaggtcccgaagaacacccggatgctggcc
ggcatcggcgagaacgccggcgtcgtgcaggtctccgacgacctggcggtcaccttcaag
gtcgagtcgcacaaccaccccagctacgtcgagccctaccagggcgcggccaccggggtc
ggcggcatcgtgcgtgacatcctggcgatgggcgcccgcccgatcgcggtgatggacccg
ctgcgcttcggcgcccacgaccacccggacaccgcccgcgtgctgcccggcgtggtggcc
ggcatcggtggctacggcaactgcctgggcctgccgaacatcggcggcgagatcgtcttc
gacccgtgttaccagggcaacccgctggtcaacgcgctctccatcggcgtgctgccggtc
gagcggctgcagaagaaggaggcgaccggcaccggcaacatcgtcgtgctgctgggcgcc
cggaccggtcgcgacggcatcggcggggtctccgtgctggcgtccgccaccttcgacgag
gaggccgagcagcgccgcccgtcggtccaggtcggcgacccgttcatggagaaactgctg
atcgagagctgcctggagctgtacgacgccggcctggtcaccggcatccaggacctcggc
ggcgccggcctgacctgcgcgctcaccgagaccgcggcggccgccggcaccggcatgcgg
gtctggctggaacgggtcccgctgcgcgaggcctcgatgtcgccgaccgagatcctggcc
agcgagtcgcaggagcggatgctcctgatcgtcaccccggagaacctcgacgcggtcctc
aaggtcgccgagaagtggggcgtctgggccaccgcgatcggcgaggtcaccccgcgcgcc
gaggacggcaccccgggccggctgcacatcacgtggaacgaccacgtcgtggtggacgtg
cccccggggtcgctcgccgacgacggcccgatctacgagcggccgctgcgcgagccgtcc
gacctgatcctgctgcaggcggaccgggccgagacgctgccccggcccaccaccggcgcc
gagctgcgcgaaaccgtgctgcggatggccgcctcgccgaacctgtgcgacaagacctgg
gtcaccgagcagtacgaccggtacgtgctgggcaacaccgtgctggcccagccggaggac
tcgggcgtgctgcggctcgacgagcagaccaacctcggcgtggcgctgtcggtcgacggc
aacggccggttcgcccgcctcgacccgtacgagggcgccaagctcgcactcgccgaggcg
taccggaacgtcgcggtcaccggggccgagccgatcgcggtcaccgactgcctgaacttc
ggctcgcccgaggacccggcggtcatgtggcagttcgcccgggccgtgcagggcctggcg
gacggctgccagcagctgggcaccccggtgaccggcggcaacgtcagcttctacaaccag
accggcgccgcggcgatccaccccaccccggtggtcggtgtgatgggcctgttcgacgac
gtcacccggcgcgtcccgatgggcttcaaggccgccggcgagctgctcttcctgctcggc
gagacccgcgaggagctgtccggctccgagtgggcctgggtgacccacggccacctcggc
gggcgtccgcccaaggtcgacctggcggccgagcagaccctgggcaggctgatggcccgc
gtctcgcagaccgggctggtcagcgcggcgcacgacctctccgacggcggcctggcccag
gtcctggtggagagctgcctgcgctacggcaccggtgcgtcggtgaccgtcgagtccgcc
ttcgtcgggctgttcagcgagtcggccgcgcgcgtcctggtgtccgtgccgcagggccac
gagaaggctttcgtggcgctcgccgccgagctgggcgtcccgtgcgccaagatcggcacc
accaccgaggccgcggccctggaggtgaccggacagttcacgattccgctggacgagctg
cgggcggcctggtcgggcacgctgccgaagctgttcggcggggctgagccggccgccgag
ggccggtcggtgacgctggagctgaccgagccgaagccgggcgggccgctgtag
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