KEGG   Actinoplanes sp. SE50/110: ACPL_7148
Entry
ACPL_7148         CDS       T02044                                 
Symbol
nrdE
Name
(GenBank) ribonucleoside-diphosphate reductase alpha chain
  KO
K00525  ribonucleoside-diphosphate reductase alpha chain [EC:1.17.4.1]
Organism
ase  Actinoplanes sp. SE50/110
Pathway
ase00230  Purine metabolism
ase00240  Pyrimidine metabolism
ase01100  Metabolic pathways
ase01232  Nucleotide metabolism
Module
ase_M00053  Deoxyribonucleotide biosynthesis, ADP/GDP/CDP/UDP => dATP/dGTP/dCTP/dUTP
ase_M00938  Pyrimidine deoxyribonucleotide biosynthesis, UDP => dTTP
Brite
KEGG Orthology (KO) [BR:ase00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    ACPL_7148 (nrdE)
   00240 Pyrimidine metabolism
    ACPL_7148 (nrdE)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03400 DNA repair and recombination proteins [BR:ase03400]
    ACPL_7148 (nrdE)
Enzymes [BR:ase01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.4  With a disulfide as acceptor
    1.17.4.1  ribonucleoside-diphosphate reductase
     ACPL_7148 (nrdE)
DNA repair and recombination proteins [BR:ase03400]
 Prokaryotic type
  Other factors with a suspected DNA repair function
   Modulation of nucleotide pools
    ACPL_7148 (nrdE)
SSDB
Motif
Pfam: Ribonuc_red_lgC Ribonuc_red_2_N TSCPD Ribonuc_red_lgN RuvA_C DUF1421
Other DBs
NCBI-ProteinID: AEV88028
LinkDB
Position
complement(7890478..7893384)
AA seq 968 aa
MAGDGITAGRQRSRTNTNGGDAAAAAGLRVERVWTTAGVHPYDEVEWERRDVVMTNWRDG
SINFEQRGVEFPTSWSVNAANIVTTKYFRGAVGTPERETSLRQLIDRVVQTYRRAGEEHG
YFASPADAEVFDHELTWMLLHQVFSFNSPVWFNVGTKSPQQVSACFILSVDDSMDSILEW
YKEEGLIFKGGSGSGVNLSRIRSSKELLSSGGTASGPVSFMRGADASAGTIKSGGATRRA
AKMVILDVDHPDIEEFVQTKAREEDKIRALRDAGFDMDLGGADIVSVQYQNANNSVRVSD
EFMRAYEEGTEFGLRGRLDGEVIETIDAKKLFRDIARAAWECADPGLQYDDTINDWHTNP
ETGRITASNPCSEYMSLDDSSCNLASLNLMKFLRADGGFEVEKFVKSVEFIITAMDISIC
FADFPTEKIGVTTRAYRQLGIGYANLGALLMASGLPYDSDGGRSVAAAITSLMTGTAYRR
SAELAGVVGAYDGYARNADAHQRVMRKHAAANDEVRAQGPVATEILREATRQWKNGNKIG
EKNGWRNAQASVLAPTGTIGLMMDCDTTGIEPDLALVKFKKLVGGGSMQIVNQTVPRALR
SLGYPEEQVEAIVEHISEHGNVVDAPGLKPEHYAVFDCAMGERSIAPIGHVRMMAAVQPF
ISGAISKTVNMPETATIEEIEEIHYQGWKLGLKALAIYRDNCKVGQPLSAGKTAKAAAPA
TVEAPAAVEKVVEKVVEYRPIRKRLPKKRPSETVSFSVGGAEGYLTASSYPDDGLGEVFL
KMSKQGSTLAGVMDAFSVAISIGLQYGVPLETYVSKFTNMRFEPAGMTDDPDVRMASSVM
DYIFRRLALDFLDYDTRAELGIFTAKERTAQAQAEAAAEAATVDLAGMAASAPAAPAVAP
AATPGTSTVTVAEAKAATPVSAGSSTELLEIKTGHAADAPLCFTCGTKMRRAGSCYVCEG
CGSTSGCS
NT seq 2907 nt   +upstreamnt  +downstreamnt
atggccggagacggcatcaccgcgggtcgccagcgcagccggacgaacacgaacggcggc
gacgcggcggcggccgcggggctgcgcgtggagcgggtgtggacgacggcgggcgtccac
ccgtacgacgaggtggagtgggagcgccgggacgtcgtcatgacgaactggcgggacggc
tcgatcaacttcgagcagcgtggcgtggagttccccacgtcctggagcgtcaacgccgcg
aacatcgtgacgaccaagtacttccgcggcgcggtggggacgcccgagcgggagacgtct
ctgcgccagctcatcgaccgggtcgtgcagacctaccgccgggccggcgaggagcacggc
tacttcgcgagcccggccgacgccgaggtcttcgaccacgagctcacctggatgctgctg
caccaggtgttcagcttcaactcgccggtctggttcaacgtcggcaccaagtcgccgcag
caggtcagcgcgtgcttcatcctctccgtggacgactcgatggactccatcctcgagtgg
tacaaggaggagggcctgatcttcaagggcggctccggctccggggtgaacctgtcccgc
atccgctcctccaaggaactgctgtcctccggcggcacggccagcggcccggtcagcttc
atgcgcggcgccgacgccagcgccggcaccatcaagtccggcggcgccacccggcgtgcc
gccaagatggtcatcctcgacgtcgaccacccggacatcgaggagttcgtgcagaccaag
gcgcgtgaggaagacaagatccgcgcgctgcgggacgccggcttcgacatggacctgggc
ggcgccgacatcgtctcggtgcagtaccagaacgccaacaactcggtgcgggtcagcgac
gagttcatgcgggcgtacgaggagggcaccgagttcggtctccgtggccgcctcgacggc
gaggtcatcgagaccatcgacgccaagaagctgttccgcgacatcgcccgggccgcctgg
gagtgcgccgaccccggcctgcagtacgacgacaccatcaacgactggcacaccaacccc
gagaccggccggatcaccgcgtccaacccgtgctcggagtacatgtcgctggacgactcg
tcctgcaacctggcctcgctcaacctgatgaagttcctccgcgccgacggcggcttcgag
gtggagaagttcgtcaagagcgtcgagttcatcatcaccgcgatggacatctcgatctgt
ttcgccgacttcccgaccgagaagatcggggtcaccacccgggcctaccggcagctcggc
atcggctacgccaacctcggcgcgctgctgatggcctccggcctgccctacgactccgac
ggtggccgcagcgtcgccgcggcgatcacctcgctgatgaccggcaccgcgtaccgccgc
tcggccgagctggccggcgtggtcggcgcctacgacggctacgcccgcaacgccgacgcg
caccagcgcgtgatgcgcaagcacgccgctgccaacgacgaggtccgcgcccagggcccg
gtcgccaccgagatcctccgtgaggccacccggcagtggaagaacggcaacaagatcggt
gagaagaacggctggcgcaacgcgcaggcgtcggtgctcgccccgaccggcaccatcggc
ctgatgatggactgcgacaccaccggcatcgagcccgacctggccctggtcaagttcaag
aagctggtcggcggcggctcgatgcagatcgtcaaccagaccgtgccgcgcgcgctgcgc
agcctcggctatcccgaggagcaggtcgaggcgatcgtcgagcacatctccgagcacggc
aacgtggtggacgcgcccggcctcaagccggagcactacgcggtcttcgactgcgccatg
ggcgagcggtcgatcgccccgatcggtcacgtccggatgatggccgcggtgcagccgttc
atctccggcgccatctccaagaccgtcaacatgccggagacggcgacgatcgaggagatc
gaggagatccactaccagggctggaagctcggcctgaaggcgctcgcgatctaccgcgac
aactgcaaggtcggccagccgctgtcggccggcaagaccgcgaaggccgccgcgcccgcc
acggtcgaggccccggccgcggtcgagaaggtcgtggagaaggtggtcgagtaccgcccg
atccgcaagcggctgccgaagaagcgcccgtccgagacggtctccttctcggtcggcggc
gccgagggctacctcaccgcgtcgtcctacccggacgacggcctcggcgaggtcttcctg
aagatgtcgaagcagggctccaccctggccggtgtgatggacgccttctcggtcgccatc
tcgataggcctgcagtacggcgtcccgctggagacgtacgtcagcaagttcaccaacatg
cgcttcgagccggccggcatgaccgacgacccggacgtgcgcatggcgtcgtcggtgatg
gactacatcttccgtcgcctggcgctggacttcctcgactacgacacccgcgccgagctg
ggcatcttcaccgccaaggagcgcaccgcccaggcgcaggccgaggccgccgccgaggct
gccacggtcgacctggccggcatggcggcgtccgctccggccgcgccggcggtcgctccg
gccgcgacgcccggcacgtccaccgtgacggtcgccgaggcgaaggccgccacgccggtc
tcggccggctcgtcgaccgaactgctggagatcaagaccgggcacgccgccgacgcgccg
ctctgcttcacctgcggcacgaagatgcgccgcgccggcagctgctacgtctgcgagggt
tgcggctcgacctccggctgcagctga

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