Actinoplanes sp. SE50/110: ACPL_7347
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Entry
ACPL_7347 CDS
T02044
Symbol
leuC
Name
(GenBank) 3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
ase
Actinoplanes sp. SE50/110
Pathway
ase00290
Valine, leucine and isoleucine biosynthesis
ase00660
C5-Branched dibasic acid metabolism
ase01100
Metabolic pathways
ase01110
Biosynthesis of secondary metabolites
ase01210
2-Oxocarboxylic acid metabolism
ase01230
Biosynthesis of amino acids
Module
ase_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ase00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
ACPL_7347 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ACPL_7347 (leuC)
Enzymes [BR:
ase01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
ACPL_7347 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
ACPL_7347 (leuC)
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Motif
Pfam:
Aconitase
AcnX
Motif
Other DBs
NCBI-ProteinID:
AEV88227
UniProt:
G8SL22
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Position
complement(8109653..8111107)
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AA seq
484 aa
AA seq
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MVGVTPDSGKPRTLAEKVWDDHVVRSAEGEPDLLFIDLHLLHEVTSPQAFDGLRLAGRKV
RRTDLTLATEDHNTPTGYADPSFNTRRGELLTIADTVSRTQIETLRKNCAEFGVEIRPLG
DVNQGIVHVIGPQLGLTQPGTTIVCGDSHTATHGAFGALAFGIGTSEVEHVLATQTLPQS
KPKTMAVTVVGELGPGVSAKDLILALITQTGTGGGNGHIVEYRGEAIRKLSMEGRMTICN
MSIEWGAKAGMIAPDETTFAYLKDRRHAPQGADWDAAVAYWKTLVTDEDAEYDTEIILDA
TRISPFITWGTNPGQGAALNDVVPNPADFPDEVERGAAERALAYMDLTPGTPFREVPVDV
VFVGSCTNGRLEDLRAAADVIRGRKVAAGVRMMIVPGSYLVREQAEAEGLDKIFTDAGAE
WRFAGCSMCLGMNPDTLSPGQRAASTSNRNFEGRQGKGGRTHLVSPQVAAATAVVGKLAA
PADL
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atggtgggagtcactcccgacagcgggaaacccaggaccctggccgagaaggtctgggat
gaccacgtggtgcgctcggccgagggagagcccgacctgctcttcatcgacctgcacctg
ctgcacgaggtcaccagcccgcaggcgttcgacggtctccggttggccggccgcaaggtc
cgccgcaccgacctcacgctggcgaccgaggatcacaacaccccgaccgggtatgcggat
ccctccttcaacacccgccgcggtgagctgctgaccatcgccgacacggtttcccgcacc
cagatcgagaccctgcggaagaactgcgccgagttcggcgtcgagatccgcccgctcggt
gacgtgaaccagggcatcgtgcacgtgatcggcccgcagctgggcctgacccagccgggc
accacgatcgtctgcggtgactcgcacaccgcgacccacggcgcgttcggcgcgctggcc
ttcggcatcggcaccagtgaggtcgagcacgtgctcgccacccagacgctgccgcagtcg
aagccgaagacgatggccgtcacggtcgtcggggagctcggcccgggcgtcagcgcgaag
gatctgatcctcgccctgatcacgcagaccggcaccggtggcggcaacggccacatcgtg
gagtaccgcggcgaggcgatccgcaagctctccatggagggccggatgacgatctgcaac
atgtcgatcgagtggggcgccaaggccggcatgatcgcgccggacgagaccaccttcgcg
tatctgaaggatcgccggcacgccccgcagggcgccgactgggacgccgccgtggcgtac
tggaagaccctggtcaccgacgaggacgcggagtacgacaccgagatcatcctggacgcc
accaggatcagcccgttcatcacctggggcaccaacccgggccagggtgccgcgttgaac
gacgtggtgccgaacccggcggacttcccggacgaggtggagcggggcgccgccgagcgc
gccctggcgtacatggacctcaccccgggcaccccgttccgcgaggtcccggtcgacgtg
gtcttcgtcggctcgtgcaccaacggccggctggaggacctgcgggccgcggccgacgtg
atccgcggccgcaaggtcgccgccggcgtccggatgatgatcgtgcccggttcctacctg
gtgcgcgagcaggcggaggccgagggcctggacaagatcttcaccgatgcgggcgccgag
tggcggttcgccggctgctcgatgtgcctgggcatgaacccggacacgctgagccccggg
cagcgcgcggcgtccacctccaaccgcaacttcgagggccggcagggcaagggtggccgc
acccacctggtctcgccgcaggtcgccgccgccaccgcggtggtcggcaagctggccgcc
ccggccgacctctga
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