Actinoplanes sp. SE50/110: ACPL_7356
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Entry
ACPL_7356 CDS
T02044
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ase
Actinoplanes sp. SE50/110
Pathway
ase00290
Valine, leucine and isoleucine biosynthesis
ase00620
Pyruvate metabolism
ase01100
Metabolic pathways
ase01110
Biosynthesis of secondary metabolites
ase01210
2-Oxocarboxylic acid metabolism
ase01230
Biosynthesis of amino acids
Module
ase_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ase00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ACPL_7356
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ACPL_7356
Enzymes [BR:
ase01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ACPL_7356
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Ortholog
Paralog
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
MEDS
DUF8495
Linker_histone
Motif
Other DBs
NCBI-ProteinID:
AEV88236
LinkDB
All DBs
Position
8120792..8122366
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AA seq
524 aa
AA seq
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MDYQVFDTTLRDGGQREGISYTVADKLAVARLLDDFGVGFIEGGWPGAMPKDTEFFARAR
TELNLRHAVLVAFGATRKAGVDVAADPQVRALLEADTPVVCVVAKSDIRHVERALRTTAE
ENLAMVRDTVRHLVANGRRAFLDCEHFFDGFRFDPEYTASVVRTAIDAGAERVIMCDTNG
GMLPSMITKAITEVVERTGVSADRLGIHCQNDTACAVANTVAAVEAGVRHFQCTANGYGE
RPGNADLFAVVSNLQLKLGLKVLPDGCLEKATRVSSALAEIANIAPDTHQAYVGAAAFAH
KAGLHASAIKVDPLLYNHVDPAVVGNDMRILVTEMAGRASIELKSRELGIDLAGHPDTLT
SVTQKVKDLEAAGWSFEAADASFELLVRSELPGEDVTRPFTLESYRVLVEHREDGKVISE
ATVKLRVKGERVIATAEGNGPVNALDEALRTALSHHHPALRSFELNDYKVRILEGSHGTN
AITRVLVETGDHNREWTTVGVHENVVEASWTALVDALTYGLGRS
NT seq
1575 nt
NT seq
+upstream
nt +downstream
nt
atggactaccaggtgttcgacacgacgctgcgcgacggtgggcagcgcgagggaatcagc
tacacggtcgccgacaaactcgcggtcgcacgcctgctggacgacttcggtgtcggtttc
atcgagggcggctggccgggcgcgatgcccaaggacaccgagttcttcgcccgcgccagg
accgagctgaacctccggcacgcggtgctggtcgcgttcggcgccacccgcaaggccggc
gtggacgtggcggccgacccgcaggtgcgggcgctgctggaggccgacaccccggtggtc
tgcgtggtggccaagtcggacatccggcacgtggagcgggcgctgcgcaccacggcggag
gagaacctggcgatggtccgggacacggtccggcacctggtcgccaacggccgccgggcg
ttcctcgactgtgagcacttcttcgacggcttccgtttcgacccggagtacaccgcgagc
gtggtgcggaccgcgatcgacgccggcgccgaacgcgtgatcatgtgcgacaccaacggc
ggcatgctcccctcgatgatcaccaaggcgatcaccgaggtcgtcgagcggaccggggtg
agcgccgaccggctcggcatccactgccagaacgacaccgcctgcgcggtcgcgaacacg
gtcgccgcggtcgaggccggggtgcggcacttccagtgcaccgcgaacggctacggcgag
cgccccggcaacgccgacctgttcgccgtggtcagcaacctgcaactcaagctcgggctg
aaggtcctaccggacggatgcctggagaaggcgacgcgggtctcctccgcgctcgccgag
atcgccaacatcgcccccgacacccaccaggcctatgtcggggccgcggcgttcgcccac
aaggcgggcctgcacgcgagcgcgatcaaagtggatccgctgctgtacaaccacgtcgac
ccggcggttgtcggcaacgacatgcggatcctggtgaccgagatggccggccgggccagc
atcgagctcaagagtcgcgagctcggcatcgacctggccggccatccggacacgctcacc
tcggtcacccagaaggtcaaggacctggaggcggccggctggtcgttcgaggccgccgac
gcctcgttcgagctgctggtgcgcagcgagctgccgggcgaggacgtgacccgcccgttc
accctggagtcgtaccgggtgctggtcgagcaccgcgaagacggcaaggtgatctccgag
gcgacggtgaagctgcgggtcaagggcgagcgggtgatcgccacggccgagggcaacggc
ccggtcaacgcgctggacgaggcgctgcgcaccgcgctctcccaccaccatccggcgctg
aggtcgttcgagctcaacgactacaaggtacggatcctggagggcagccacggcaccaac
gcgatcacccgggtgctggtcgagaccggcgaccacaaccgcgagtggaccaccgtcggc
gtgcacgagaacgtggtcgaggccagctggaccgccctggtcgacgcgctcacctacgga
ctcggcaggagctga
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