KEGG   Actinoplanes sp. SE50/110: ACPL_8376
Entry
ACPL_8376         CDS       T02044                                 
Symbol
ddlA
Name
(GenBank) D-alanine-D-alanine ligase
  KO
K01921  D-alanine-D-alanine ligase [EC:6.3.2.4]
Organism
ase  Actinoplanes sp. SE50/110
Pathway
ase00470  D-Amino acid metabolism
ase00550  Peptidoglycan biosynthesis
ase01100  Metabolic pathways
ase01502  Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:ase00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    ACPL_8376 (ddlA)
  09107 Glycan biosynthesis and metabolism
   00550 Peptidoglycan biosynthesis
    ACPL_8376 (ddlA)
 09160 Human Diseases
  09175 Drug resistance: antimicrobial
   01502 Vancomycin resistance
    ACPL_8376 (ddlA)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01011 Peptidoglycan biosynthesis and degradation proteins [BR:ase01011]
    ACPL_8376 (ddlA)
Enzymes [BR:ase01000]
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.4  D-alanine---D-alanine ligase
     ACPL_8376 (ddlA)
Peptidoglycan biosynthesis and degradation proteins [BR:ase01011]
 Precursor biosynthesis
  Amino acid ligase
   ACPL_8376 (ddlA)
SSDB
Motif
Pfam: Dala_Dala_lig_C Dala_Dala_lig_N ATP-grasp CPSase_L_D2 ATP-grasp_3
Other DBs
NCBI-ProteinID: AEV89252
LinkDB
Position
9226619..9227581
AA seq 320 aa
MITTMELRVLVLAGGLSYERDVSLRSGRRVLDALRSRGIEAELHDADVSLLPALQADPPD
AVVIALHGATGEDGSLRGVLDLCAVPYVGADARTARLAWDKPSAKARLRESGIPTPDWVA
LPHDRFSELGAVAVLDRIVSRLGLPLMVKPAQGGSGLGAAVVRDAADLPAAMVGCFAYDS
TALVEQYVSGTRLAVSIVDLGSGPRALPIVEIVPRDGVYDYAARYTAGLTTWHVPARLSA
AVASRVSETALAAYQALGLRDLSRIDVIVGEDGEAQVLGCNVSPGMTETSLLPLAVQADG
ADLGEILGVLVERAVDRKAL
NT seq 963 nt   +upstreamnt  +downstreamnt
atgatcaccaccatggagttgcgagtcttggttctggccggcgggctttcctacgagcgg
gacgtctcgctgcggtccgggcgccgggtgctggatgcgctcaggtcccggggcatcgag
gccgaactgcacgacgccgacgtgtccctgctcccggcgctgcaggccgacccgcccgac
gcggtggtgatcgcgctgcacggggccaccggcgaggacgggtcgctgcgcggggtgctc
gacctgtgcgcggtgccgtacgtgggggccgacgcccgcaccgcccgcctcgcctgggac
aagccgtccgccaaagcacgcttgcgggagtcgggcatcccgacgccggactgggtggcg
ttgccgcacgaccggttctccgaactgggggcggtggcggtcctcgaccggatcgtgtcc
cggctcggtctgccgctgatggtgaaaccggcgcagggcggcagtgggttgggcgccgcg
gtggtccgggacgcggcggacctgccggcggccatggtgggctgtttcgcgtacgactcg
accgcgctggtcgagcagtacgtcagcggaacccggctggcggtgtcgatcgtcgacctg
gggtcggggccacgggcgctgccgatcgtggagatcgtgccgcgggacggggtgtacgac
tacgcggcccgatacacggcggggctgacgacgtggcatgtgccggcccggctgtcggcg
gcggtggcgtcccgggtgagtgagacggccctggcggcgtatcaggccctggggttgcgg
gacctctcccggatcgacgtgatcgtgggggaggacggggaagcgcaggtcttggggtgc
aacgtttcgccggggatgacggagacgtcgttgctgccgttggcggttcaggctgatggg
gcggacctgggagagatcctgggggttctggtggaacgggcggttgatcggaaggctctt
tag

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