Aggregatibacter segnis: NCTC10977_00862
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Entry
NCTC10977_00862 CDS
T06075
Symbol
purL
Name
(GenBank) Phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
aseg
Aggregatibacter segnis
Pathway
aseg00230
Purine metabolism
aseg01100
Metabolic pathways
aseg01110
Biosynthesis of secondary metabolites
Module
aseg_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
aseg00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
NCTC10977_00862 (purL)
Enzymes [BR:
aseg01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
NCTC10977_00862 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
AIRS
Motif
Other DBs
NCBI-ProteinID:
SQH64336
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Position
1:832586..836479
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AA seq
1297 aa
AA seq
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MFQTFRGSPALSEFRINGLMQKFQQQQLPVKSVYAEYVHFVALNDALSAEQEAKLKALLH
YGPTLAEHEAKGESFIVIPRVGTISSWSSKATDIAHNCGLNEVERIERGLAYYFELTQPL
DEKTTEKLTALLHDRMMETVVRKADEAEVLFRQQEPKPFKTVDILNGGRSALESANVELG
LALAEDEIDYLMENFTALGRNPHDIELYMFAQANSEHCRHKIFNADWIIDGKKQDKSLFK
MIKNTFEKTPDFVLSAYKDNAAVMEGSKAGRFFPDEDGIYRYHNEDTHILMKVETHNHPT
AISPFPGAATGSGGEIRDEGATGRGAKPKAGLVGFSVSNLCIPNFEQPWEAPLSKPNRIA
SALDIMLEGPLGGAAFNNEFGRPALLGYFRTYEQKVNSFNGEEVRGYHKPIMLAGGIGNI
RAEHVQKGDIPVGAKLVVLGGPAMNIGLGGGAASSMASGKSKENLDFASVQRDNPEMERR
CQEVIDRCWQLGDDNPIAFIHDVGAGGLSNAMPELVHDGGRGGKFELRKILSDEREMSPL
EIWCNESQERYVLAIHPEKLPHFEELCRRERAPYAVIGEATEEEHLTLHDEHFNNDPIDL
PMGVLLGKTPKMTRDVQTASVNGEPLEQSQIQLKEALHRVLRLPAVAEKTFLITIGDRTV
TGMVARDQMVGPWQVPVADCAVTTATLDSYYGEAMSMGERTPVALLDFAASARLAVAESL
TNIAATNIGDIKRIKLSANWMSAAGHKGEDAGLYAAVKAVGEELCPQLGLTIPVGKDSMS
MKTTWQENGEQKSVTSPLSLIISAFARVEDVRKTVTPQLRTDKGQSRLLLVDLGEGNNRL
GATALAQVYAQLGDKPADVVNADTLKNFFNAMQELVAQEKLLAYHDRSDGGLIVTLAEMA
FAGHCGVAVDISALGDNDLAVLFNEELGAVIQVRDSDLSLVRDVFAKHNVLHLVKELGAV
TEDDEIEITRGNKVLLNEKRSELRGIWAELTHQMQRLRDNPECADQEFSAKKNLQDKGFS
AHLTYDPSEDIAAPYIATGKRPKVAVLREQGVNSHVEMAAAFDRAGFEAIDVHMSDLHNR
RYDLQHFNALVACGGFSYGDVLGAGGGWAKSILFNPHLRDQFSQFFEREDTLALGICNGC
QMLSTLAEIIPGTENWPRFVRNKSERFEARAALVRINESNSLWFQGMAGSHMPIAVSHGE
GRVEFKTPGDLTALQGQNLIVAQYIDNNLNPTEVYPANPNGSALGITALSNTDGRVAIMM
PHPERVFRTVSNSWHPEEWGEDGAWMRVFRNARVVFK
NT seq
3894 nt
NT seq
+upstream
nt +downstream
nt
atgttccaaactttccgtggctctcctgccctttccgaattccgtatcaatggcttaatg
caaaaattccaacagcaacaattaccggtgaaatccgtgtatgcggaatatgtgcatttt
gtggcattaaatgacgcactttctgctgaacaggaagccaaactgaaagccttgttgcat
tacggtccaaccttggcagaacatgaagccaaaggggaaagttttattgtgattccgcgt
gtcggcacgatttcctcttggtcctccaaagctaccgatatcgcccacaactgcggctta
aacgaagtggaacgtattgagcgtggtttggcgtattactttgaattgacacagccgtta
gatgaaaaaacaacggaaaaactgaccgcacttttacatgaccgcatgatggaaaccgtc
gtacgcaaggcagacgaggcggaagtgttgttccgtcaacaagaaccaaaaccgttcaaa
accgtggatattttaaacggtggacgcagtgccttagaaagtgccaacgtggaacttgga
ttggcgttggcggaagatgaaattgattatttgatggaaaatttcaccgcacttggacgc
aatccgcacgacatcgaactgtacatgttcgcgcaagccaactcggaacactgtcgccac
aaaatttttaacgccgactggattatcgacggcaaaaaacaggacaaatccctgttcaaa
atgatcaaaaatacctttgagaaaacccctgattttgtgctttccgcgtataaagacaac
gcggcagtgatggaaggttccaaagcgggacgtttcttcccagatgaagacggcatttac
cgttatcacaatgaagacacccacattttgatgaaagtggaaacccacaaccacccgacc
gccatttctccgttcccgggggcggcaaccggctccggtggggaaatccgtgacgaaggc
gcgaccggtcgtggtgcaaaaccgaaagcgggtttggtgggcttctctgtatccaactta
tgcataccaaactttgaacaaccttgggaagcgccgctttccaaaccgaaccgtattgct
tccgctttagacattatgctggaaggtccgttaggtggtgcagcgtttaacaacgaattc
ggtcgtcctgcattgcttggctatttccgtacttacgaacaaaaagtgaatagcttcaat
ggcgaagaagtgcgcggctaccacaaaccgatcatgttggcaggcggtatcggcaacatt
cgtgccgaacacgtgcaaaaaggcgacattccggtgggcgcaaaattggttgtgcttggc
ggtccggcaatgaacatcggcttaggcggtggtgccgcctcttctatggcatccggtaaa
tccaaagaaaacttggatttcgcctccgtacaacgggataaccctgaaatggaacgtcgc
tgccaagaagtgatcgaccgttgctggcagctaggcgacgacaacccgattgcctttatt
cacgacgtgggcgcgggcggtttatctaacgccatgccggaattggtgcatgacggcggt
cgtggcggtaaatttgaacttcgtaaaatcttaagcgatgagcgcgaaatgagcccgttg
gaaatttggtgtaacgaatcgcaagagcgttatgtgcttgccattcatccggaaaaacta
ccgcactttgaggaactctgccgtcgtgaacgcgcgccttatgcggtgatcggcgaagct
acggaagaagaacatttaaccttacacgacgagcatttcaacaacgatccgattgattta
ccgatgggcgtgttgctcggcaaaaccccgaaaatgacccgcgatgtgcaaaccgctagc
gttaacggcgaaccgcttgaacaaagccaaattcaattaaaagaggcgttacatcgcgta
cttcgtttaccggcagtggcggaaaaaaccttcttaattaccatcggtgaccgcacggtg
accggcatggtggcacgtgatcaaatggtcggcccgtggcaagtaccggtggcagactgc
gcggtgaccacggcgacattagacagctactacggcgaagccatgtctatgggtgaacgt
acgccggtagcattgctagatttcgctgcgtctgcccgtttagctgtggcagaatcctta
accaacattgccgccacgaatatcggcgacattaaacgcattaaattatctgccaactgg
atgtctgccgcaggccataaaggcgaagacgcgggcttatacgctgcggtgaaagccgtg
ggcgaagagctttgcccacaattaggcttaaccatcccggtaggcaaagactccatgtcc
atgaaaaccacttggcaggaaaacggcgagcaaaaaagcgtgacctcaccgctttctttg
atcatcagcgcctttgctcgcgtggaagacgtgcgcaaaaccgtcaccccacaattacgc
accgataaaggacaatcccgcttgttgttggtggatttgggcgaaggcaacaaccgctta
ggcgctacggcgttagcacaggtgtatgcgcaacttggcgacaaaccggcggatgtggtc
aacgctgatacgctgaaaaatttctttaacgccatgcaggaattggtggcgcaagaaaaa
ttattggcatatcacgaccgctccgatggcggattaattgtcaccttggcagaaatggca
tttgccggacattgtggcgtggcagtggatatcagcgccttgggtgacaacgatttagcc
gtgttatttaacgaagaattgggtgcagtgattcaagtgcgcgacagcgatttgagtctc
gtgcgcgatgtctttgccaaacacaatgtgttgcatttggtgaaagaattgggtgccgtg
actgaagacgacgaaattgaaatcacccgtggcaacaaagtgttactcaatgaaaaacgc
tcagaattacgcggtatttgggcggaattgactcatcaaatgcaacgcttacgcgacaac
ccggaatgtgccgaccaagaattttcggcgaagaaaaatctgcaggacaaaggcttctcc
gcccatttaacttacgacccaagcgaagacattgctgcgccttatattgccaccggaaaa
cgcccgaaagtggcggtgttgcgtgagcaaggcgtcaacagtcatgttgaaatggcggcg
gcatttgaccgtgccggctttgaggccattgatgtacacatgagcgacttgcataatcgc
cgttatgacttgcaacacttcaatgcattggtggcgtgcggcggcttctcttacggcgac
gtgcttggcgccggtggcggttgggcgaaatccattttatttaacccgcacttacgggat
caattcagccaattctttgaacgtgaagacacgctcgcacttggtatttgcaacggctgt
caaatgctttccaccttggcagaaattattccgggcacggaaaactggccgcgtttcgtg
cgtaacaaatccgaacgttttgaagcccgtgccgccttggttcgcattaacgaaagcaac
tctctgtggttccaaggcatggcaggctcccacatgccaattgccgtttcccacggcgag
ggcagagtggaattcaaaacacccggagatctgaccgcacttcaagggcaaaacttaatt
gtggcgcaatacatcgacaacaacctcaacccgacagaagtgtacccggcaaacccgaac
ggctccgcccttggcatcaccgccctttccaacacggatggacgcgtcgccatcatgatg
ccacacccggaacgtgtcttccgcaccgtgagcaactcatggcatccggaagagtgggga
gaagatggagcttggatgcgggtgtttaggaatgcgagggttgtgtttaaataa
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