Alkalimarinus sediminis: NNL22_05615
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Entry
NNL22_05615 CDS
T08621
Symbol
folC
Name
(GenBank) bifunctional tetrahydrofolate synthase/dihydrofolate synthase
KO
K11754
dihydrofolate synthase / folylpolyglutamate synthase [EC:
6.3.2.12
6.3.2.17
]
Organism
asem
Alkalimarinus sediminis
Pathway
asem00790
Folate biosynthesis
asem01100
Metabolic pathways
asem01240
Biosynthesis of cofactors
Module
asem_M00126
Tetrahydrofolate biosynthesis, GTP => THF
Brite
KEGG Orthology (KO) [BR:
asem00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
NNL22_05615 (folC)
Enzymes [BR:
asem01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.12 dihydrofolate synthase
NNL22_05615 (folC)
6.3.2.17 tetrahydrofolate synthase
NNL22_05615 (folC)
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Motif
Pfam:
Mur_ligase_C
Mur_ligase_M
Motif
Other DBs
NCBI-ProteinID:
UZW76059
UniProt:
A0A9E8HKE8
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Position
1250286..1251593
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AA seq
435 aa
AA seq
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MSNQYQTELDSWLNRIEQNHPSEIEMGLDRTLTVYSKLRKKRLAKRIVVVAGTNGKGSTI
AAMERLLLDAGQRVGVYTSPHIKAYNERVRIDGELIDNKRLVDSFNEVEQARGGTPLTYF
EFGTLSALCCFQKEDLDVVLLEVGLGGRLDAVNIVDADLSIITSVDIDHIEWLGDNRESI
GFEKAGIFRQGVPAIYGEGNPPHSVIQQANAQQINLLTYQQHFGMGAQENNSSNQYDWLY
QPQRQHQSQRTTAYIAQPDGESKDISMPFSLLPESNLLTAVQAMQCLGYAVDNEQVHQSL
DGFAVDGRFQVYDTDPLVLLDVGHNPHAAKFLASRLAGIKRNRPVYGVFSMLADKDVQGV
IEGLGSQITEWHVAPLVCDRAMAISEICEGLTRYNQVYFEHDSLDMAYQKARNAAKQNDG
IVMCFGSFHVVSDID
NT seq
1308 nt
NT seq
+upstream
nt +downstream
nt
atgagtaatcaatatcagacagagcttgactcatggcttaaccgaatagagcaaaatcac
ccctctgagattgagatggggctagatagaacgctcaccgtctactctaaactcagaaaa
aaacgattggcaaaacgcattgttgtagtcgcaggtaccaatggcaaaggctcgactatt
gcagcgatggagcgattgttgttagatgcaggtcagcgggtgggtgtttatacctccccc
catattaaggcatataacgagcgtgtacgcattgatggtgagcttattgataataagcgc
ctcgttgatagctttaatgaagtagagcaggctcgaggtggtacgcctttgacctatttc
gaattcggaacccttagtgctctctgctgttttcaaaaagaagatctcgatgttgtgctc
cttgaggtagggctaggagggcgactcgatgccgttaatatcgtcgacgcagacctatcg
atcatcacctcagtcgatattgatcatattgagtggcttggtgataatcgagaaagcatc
ggctttgaaaaagcgggtattttccgccaaggtgtgcctgctatctatggtgagggcaac
ccaccccacagtgttattcaacaagctaacgcccaacagatcaatctgctcacctatcag
cagcattttggcatgggggcgcaagagaacaatagcagtaaccaatatgactggctttac
caacctcagagacaacatcaaagtcagcgtacaacggcctatatcgctcaacccgatggc
gagtcgaaagatatttcgatgcctttcagtttgctgcctgagagcaatctattaaccgct
gttcaagcgatgcagtgtttaggttatgccgtcgataatgagcaggtacaccagagtcta
gacggttttgctgtcgatggtcgttttcaggtttatgatactgacccgctggtgttgttg
gatgttggacataacccgcatgctgcaaaattcctcgctagccgattagcagggataaaa
agaaaccgacccgtgtatggggtcttttcaatgttagcagacaaggatgttcaaggggtt
atcgaagggcttggtagccagattaccgaatggcatgtggctcctttagtttgtgatagg
gcaatggctatctccgagatatgtgaagggcttactaggtataatcaagtttactttgaa
catgactctcttgatatggcatatcaaaaagcgcgtaatgcagccaaacaaaatgacggt
attgtaatgtgttttggctcctttcatgttgtatctgatatagactaa
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