Aeromicrobium senzhongii: H9L21_05995
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Entry
H9L21_05995 CDS
T09535
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
asez
Aeromicrobium senzhongii
Pathway
asez00300
Lysine biosynthesis
asez00550
Peptidoglycan biosynthesis
asez01100
Metabolic pathways
asez01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
asez00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
H9L21_05995
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
H9L21_05995
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
H9L21_05995
Enzymes [BR:
asez01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
H9L21_05995
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Gene cluster
GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QNL95469
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Position
1185447..1186805
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AA seq
452 aa
AA seq
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MIRTTLAQIAEATRGRVEGDDTLAVHGPAVVDSRRVVPGSLFVAIPGERVDGNDFVGTAL
DAGAVASLATREVPGPHVLVDEPVHALGLLATDRLAALRRGADVTVVAVTGSQGKTSVKD
LMAHVLSTRGATVAPEGSFNNELGVPLTVLRADEGTRNLVLEMGARGIGHIATLCAIAPP
DVAVVLNVGSAHAGEFGGLDRTAQAKGELVEALGPDGIAVLNADDPRVAAMASRTRGRVV
TFGRAGDVRLVGDVTLDEDGYPHFVLEVDGERYEATVPQLGDHQAMNAAAAVAATTAAGV
PVADAVAALAGAHAASPMRMERHRTSTGAVVINDAYNANPESMSAALRTLAELAPGRGVA
VLGEMLELGEESPDQHRRIGRLAADLGIARVVAVGAAAADIAEGAGPVGESVPDVETAVT
VVSASLDPDAVVLVKASRGARLERVAEALLRD
NT seq
1359 nt
NT seq
+upstream
nt +downstream
nt
gtgatccgcacgacactggcccagatcgccgaggcgacgcgcggacgcgtggagggcgac
gacaccctcgccgtccacggtcccgccgtcgtcgactcccgccgggtcgtgcccggatcg
ctgttcgtcgcgatccccggtgagcgggtcgacggaaacgacttcgtcgggacggccctg
gacgccggcgccgtcgcgagcctggccacccgcgaggtgcccggaccgcacgtgctggtg
gacgagcccgtccacgccctcggcctgttggcgaccgatcggctggcggcgctgcgccgc
ggggccgacgtcaccgtggtggccgtgacggggtcgcagggcaagaccagcgtcaaggac
ctgatggcgcacgtcctctcgacgcgcggcgccaccgtcgcgcccgagggctccttcaac
aacgagctcggcgtgccgctgacggtgctgcgtgccgacgagggcacccggaacctggtc
ctcgagatgggggcgcgtggcatcggccacatcgccacgctctgcgcgatcgccccgccc
gacgtggcggtcgtcctgaacgtcggcagcgcccatgcgggggagttcggcggtctcgac
cgcacggcgcaggccaagggcgagctggtcgaggccctcggtcccgacggcatcgcggtc
ctcaacgccgatgacccgcgcgtggccgcgatggcctcgcgcacgcgcggccgcgtcgtg
accttcggccgggccggcgacgtccgcctcgtgggggacgtcaccctcgacgaggacggg
tacccgcacttcgtcctcgaggtcgacggtgagcggtacgaggccaccgtgccccagctg
ggcgaccaccaggccatgaacgccgccgccgcggtggccgccacgacggcggcgggcgtg
cccgtcgcggacgccgtggccgctctggccggggcccacgcggcgtcgcccatgcggatg
gagcgccaccggaccagcacgggtgcggtggtcatcaacgacgcctacaacgcgaacccc
gagtccatgtccgcggccctgcgcaccctggccgagctggccccgggacgcggcgtcgcc
gtcctcggtgagatgctggaactgggcgaggaatcgccggatcagcaccgccgcatcggt
cggctcgcagccgacctcggaatcgcgcgggtcgtcgccgtgggcgcggccgccgcggac
atcgcggagggcgccggtccggtcggggagtcggtcccggacgtcgagacggccgtgacc
gtcgtctccgcgagcctggaccccgatgctgtggtgcttgtgaaagcatcgagaggcgcc
cgcctcgagcgggtcgccgaagcgctgttgcgcgactga
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