Actinoplanes sichuanensis: Q0Z83_094070
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Entry
Q0Z83_094070 CDS
T09497
Name
(GenBank) bifunctional uroporphyrinogen-III C-methyltransferase/uroporphyrinogen-III synthase
KO
K13542
uroporphyrinogen III methyltransferase / synthase [EC:
2.1.1.107
4.2.1.75
]
Organism
asic
Actinoplanes sichuanensis
Pathway
asic00860
Porphyrin metabolism
asic01100
Metabolic pathways
asic01110
Biosynthesis of secondary metabolites
asic01120
Microbial metabolism in diverse environments
asic01240
Biosynthesis of cofactors
Module
asic_M00121
Heme biosynthesis, plants and bacteria, glutamate => heme
asic_M00846
Siroheme biosynthesis, glutamyl-tRNA => siroheme
asic_M00926
Heme biosynthesis, bacteria, glutamyl-tRNA => coproporphyrin III => heme
Brite
KEGG Orthology (KO) [BR:
asic00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00860 Porphyrin metabolism
Q0Z83_094070
Enzymes [BR:
asic01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.107 uroporphyrinogen-III C-methyltransferase
Q0Z83_094070
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.75 uroporphyrinogen-III synthase
Q0Z83_094070
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Motif
Pfam:
HEM4
TP_methylase
B12-binding
Motif
Other DBs
NCBI-ProteinID:
BEL11216
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Position
10145821..10147407
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AA seq
528 aa
AA seq
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MTTRTARKPAGRIAFIGAGPGDPELLTRRAYAALTDADQVVYDRGVPDSLLSAIRSDAKE
DAQFSPAEGAPGDVAKVLLSAAKSGLSAVHLVAGDPFGHDSVVKEVQAVARTAVHFEVIP
GIGQAEGVATYAGVPLPGVRIAADVDDVTNLDFDALATAAQKGSFAVAVDAGDLAAVRDG
LLAAGVEPGVPVGVTGDGTGETQYTTTSTVDSFVAAALGFTGRVVLTVGSDVAERDSLSW
WENRPLYGWKVLVPRTKEQAGAMSARLRAYGAIPCEVPTIAVEPPRTPAQMERAVKGLVD
GRYAWVIFTSVNAVRAVWEKFGEHGLDARHFGGVKIACIGEATADAVRAFGIQPELIPAG
EQSSDGLLAEFSPHDEILDPVGRVLLPRADIATETLAAGLIERGWEVDDVTAYRTVRAAP
PPAEIRDAIKSGGFDAVLFTSSSTVRNLVGIAGKPHARTVVAVIGPKTAETAVEFGLRVD
TQPQNASVPDLVEALAEYALELREKLAAMPAKQRRGSKVQGPTALRFR
NT seq
1587 nt
NT seq
+upstream
nt +downstream
nt
atgaccacccgcaccgcccgtaagccagccggacgcatcgcgttcatcggcgccggaccc
ggcgacccggagctgctgacccgccgcgcgtatgcggcgctgaccgatgccgaccaggtg
gtctacgaccgcggcgtgcccgattccctgctcagcgcgatccgttccgacgccaaggag
gacgcgcagttcagcccggccgagggcgcccccggtgacgtcgccaaggtgctgctctcc
gcggccaagtccggcctgtccgccgtacacctggtcgccggtgacccgttcggccacgac
tcggtggtcaaggaggtgcaggcggtcgcgcggaccgcagtgcacttcgaggtcatcccc
ggtatcgggcaggccgagggcgtcgccacctacgccggtgtgccgctgcccggcgtgcgg
atcgccgccgacgtcgacgacgtcaccaacctcgacttcgacgcgctcgccacggccgcc
cagaagggctccttcgcggtggccgtggacgccggcgacctcgccgccgtccgggacggg
ctgctcgccgcgggtgtcgagccgggtgtcccggtcggcgtcacgggtgacggcaccggc
gagacgcagtacaccaccacctcgaccgtggacagcttcgtcgcggcggcgctcggcttc
accggccgggtcgtgctgaccgtcggctccgacgtggccgagcgggacagcctcagctgg
tgggagaaccgcccgctgtacggctggaaggtcctcgtcccgcggaccaaggagcaggct
ggcgcgatgtccgcccggctccgtgcctacggcgcgatcccgtgcgaggtgccgaccatc
gcggtcgagccgccgcgtaccccggcgcagatggagcgggccgtcaagggcctggtcgac
ggccggtacgcgtgggtcatcttcacctcggtcaacgcggtccgcgcggtctgggagaag
ttcggcgagcacggcctggacgcccggcacttcggtggcgtgaagatcgcctgcatcggt
gaggccaccgccgacgcggtccgcgcgttcggcatccagccggagctgatcccggccggc
gagcagtcctcggacggtctgctggccgagttctcgccgcacgacgagatcctcgacccg
gtcggccgggtgctgctgccgcgggccgacatcgcgaccgagactctcgcggccgggctg
atcgagcgcggctgggaggtggacgacgtcacggcgtaccggacggtccgcgccgccccg
ccgcccgccgagatccgcgacgcgatcaagtccggcggtttcgacgcggtgctcttcacc
tcgtcctcgaccgtccgcaacctggtcggcatcgccggcaagccgcacgcccgtacggtc
gtcgcggtgatcggcccgaagaccgccgagaccgccgtcgagttcggcctccgggtcgac
acccagccgcagaacgcctcggtgcccgacctggtcgaggcgctcgccgagtacgcactg
gagctccgcgagaagctggccgcgatgccggccaagcagcgccgcggctccaaggtgcag
ggcccgacggctctgcgtttccgctga
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