Aeromonas simiae: FE240_04775
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Entry
FE240_04775 CDS
T07073
Symbol
thrA
Name
(GenBank) bifunctional aspartate kinase/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
asim
Aeromonas simiae
Pathway
asim00260
Glycine, serine and threonine metabolism
asim00261
Monobactam biosynthesis
asim00270
Cysteine and methionine metabolism
asim00300
Lysine biosynthesis
asim01100
Metabolic pathways
asim01110
Biosynthesis of secondary metabolites
asim01120
Microbial metabolism in diverse environments
asim01230
Biosynthesis of amino acids
Module
asim_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
asim_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
asim_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
asim00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
FE240_04775 (thrA)
00270 Cysteine and methionine metabolism
FE240_04775 (thrA)
00300 Lysine biosynthesis
FE240_04775 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
FE240_04775 (thrA)
Enzymes [BR:
asim01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
FE240_04775 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
FE240_04775 (thrA)
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GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
QFI54069
UniProt:
A0A5J6WSG8
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All DBs
Position
997412..999871
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AA seq
819 aa
AA seq
DB search
MRVMKFGGSSLADPERFLRAAEIVMNTHRQSQVALVLSAPAKVTNHLVALVEQTSRGMDG
HQTLAEIRAIFERVLSGLKEACPAFDEVALKARLDEELGTVERLAGGISQLGQCPDNVQA
RILSRGENLSIAFMTALLQARGIETGFICPEQMLVTDGNFLEAHVNIEASRERFAAAPLD
HQRFYLMPGFTGGNEKGETVLLGRNGSDYSAAVLAACVDAECCEIWTDVDGCYSCDPRLV
PDAYLLKTLSYKEAMELSYFGAKVLHPKTVAPVAQFQIPCLIKNTFNPQGPGTLIGPESG
DDDLKVKAISDLAGMCMFNVSGPGMKGMVGMAGRIFTAVSRAGVSIVLITQSSSEYSVSF
CIHSYDEQKTRKVIEREFALEFKNQLLDPLEVVSDLAIISLIGDGMRTAKGMAARFFTSL
AQASINIVAIAQGSSERSISAVVRAGKVAEAIKACHQNFFGSQQFIDLFMVGVGGVGEAL
VEQIRRQQPVLAEQGIGLRVVALANSRQMVSCPDGLKLDNWKALLAEGRESFTLESVKRL
VAESHIINPVIVDCTSSEDIAAQYADFLAAGFHVVTPNKKANTSSMSYYRALRRTALQTR
RKFLYETNVGAGLPVIENLQNLIKAGDRLRAFDGILSGSLSFIFGKLDEGMAFSEATKVA
RGNGFTEPDPRDDLSGMDVARKLLILAREAGMPLELSDVEVEQALPPGFDASGDVEAFMA
RLPEADAWFRDQFALAQKEGKVLRYVGSIEGGKCKVAIKAVGPDEPLFKVKDGENALAFF
SSYYQPIPLVLRGYGAGTEVTAAGVFADILRTQNWQQEV
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgtgtgatgaagtttggtggatccagtctggcggatccggagcgttttctgcgggcc
gccgagatcgtcatgaacacccaccgacagtcccaggttgccctggtgctgtcggccccg
gccaaggtcactaatcatctggttgcgctggtcgagcagaccagccgtggtatggatggc
catcaaaccctcgccgagatccgcgccatcttcgagcgggtactgagtggtttgaaagag
gcctgccccgcctttgatgaggtcgctctcaaggcgcgtctggacgaggagctcggcact
gtcgagcgtctggcaggcggcatcagccagctcggtcagtgccccgataacgtgcaggcg
cgcatcttaagccgtggcgagaacctctccatcgccttcatgaccgccctgttgcaggcg
cgcggcatcgaaaccggcttcatctgccccgagcagatgctggtgaccgacggcaatttc
ctcgaagcccacgtcaatatcgaggcctcgcgcgagcgctttgccgccgcccctctcgat
caccagcgcttctatctgatgccgggcttcacgggtggcaacgagaagggcgaaaccgtg
ctgctggggcgcaacggctctgactactccgccgccgtgctggccgcctgcgtcgatgcc
gagtgctgcgagatctggaccgacgtggatggctgctacagctgcgatccgcgcctggtg
ccggatgcctatctgctcaaaaccctctcctacaaagaggcgatggagctctcttatttc
ggcgccaaggtgctgcacccgaaaaccgtcgccccggtggctcagttccagatcccctgc
ctcatcaagaacaccttcaacccgcaaggccccggcaccctgatcggccctgagagcggc
gatgacgacctcaaggtcaaggccatctcggatctggccggcatgtgcatgttcaacgtc
tccggccccggcatgaagggcatggtggggatggccgggcgtatcttcaccgccgtttcg
cgcgccggggtgagcattgtgctcatcacccagtcatcgagcgaatacagcgtcagcttc
tgtatccacagctatgacgagcagaagactcgcaaggtgatcgagcgcgagttcgcgctg
gagttcaaaaaccagctgctcgacccgcttgaggtggtgagcgatctggccatcatctcg
ctgatcggtgacggcatgcgcacggccaaggggatggcggcccgcttctttacctccttg
gctcaggcctctatcaacatcgtcgccatcgcccagggctcgagcgagcgctccatctcg
gcggtggtgcgtgccggcaaggtggccgaggccatcaaggcgtgccaccagaacttcttc
ggcagccagcagttcatcgatctgttcatggtcggtgtgggcggcgtcggcgaggcgctg
gtcgagcagatccgccgtcagcagccggtgctggccgagcagggcatcggcctgcgcgtg
gtggcactggctaacagccgccagatggtgagctgccccgacggtctgaaactcgacaac
tggaaggcgctgctggccgagggacgcgagagcttcaccctggagtcggtcaagcggctg
gtggccgagagccacatcatcaacccggtgatcgtcgattgcacctccagtgaggatatc
gcggcccaatacgctgacttcctggccgctggtttccacgtggtgaccccgaacaagaag
gccaacaccagctcgatgagctactaccgcgccctgcgccgcaccgccttgcagacccgc
cgcaagttcctctacgagaccaacgtgggcgcgggcctgccggtcatcgagaacctgcaa
aacctcatcaaggccggcgatcgcctgcgcgccttcgacggcatcctgtcgggctcgctc
tcgtttatcttcggcaagctcgacgaggggatggcctttagcgaggcgaccaaggtggcc
cgcggcaacggcttcaccgagccggacccgcgcgatgacttaagcggcatggacgtggcg
cgcaagctgctgatcctggcccgtgaggccggcatgccgctggagctttctgatgtggag
gtcgagcaggccctgccgcccggctttgacgccagcggtgacgtcgaggccttcatggcc
cgcctgcccgaggccgacgcctggttccgcgatcagttcgcgctggcgcaaaaagagggc
aaggtgctgcgctacgtgggctccatcgagggcggcaagtgcaaggtcgccatcaaggcg
gttgggccggatgagccgctattcaaggtcaaggatggggagaacgcgctcgccttcttc
tccagctactaccagccgatccccctggtgctgcgcggctatggcgctggcaccgaggtg
accgccgccggggtgtttgccgacatcctgcgcacccaaaactggcaacaggaggtatga
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