Actinomyces slackii: NCTC11923_01130
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Entry
NCTC11923_01130 CDS
T06783
Symbol
iolA
Name
(GenBank) Methylmalonate semialdehyde dehydrogenase [acylating]
KO
K00140
malonate-semialdehyde dehydrogenase (acetylating) / methylmalonate-semialdehyde dehydrogenase [EC:
1.2.1.18
1.2.1.27
]
Organism
asla
Actinomyces slackii
Pathway
asla00280
Valine, leucine and isoleucine degradation
asla00410
beta-Alanine metabolism
asla00562
Inositol phosphate metabolism
asla00640
Propanoate metabolism
asla01100
Metabolic pathways
asla01120
Microbial metabolism in diverse environments
asla01200
Carbon metabolism
Brite
KEGG Orthology (KO) [BR:
asla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
NCTC11923_01130 (iolA)
00562 Inositol phosphate metabolism
NCTC11923_01130 (iolA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
NCTC11923_01130 (iolA)
09106 Metabolism of other amino acids
00410 beta-Alanine metabolism
NCTC11923_01130 (iolA)
Enzymes [BR:
asla01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.1 With NAD+ or NADP+ as acceptor
1.2.1.18 malonate-semialdehyde dehydrogenase (acetylating)
NCTC11923_01130 (iolA)
1.2.1.27 methylmalonate-semialdehyde dehydrogenase (CoA-acylating)
NCTC11923_01130 (iolA)
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Motif
Pfam:
Aldedh
Motif
Other DBs
NCBI-ProteinID:
VEG74496
UniProt:
A0A3S4WJU8
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Position
1:1363539..1365032
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AA seq
497 aa
AA seq
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MKTLSHWIDGKYYEGTPIGRFPVENPGTGEVEKELLQASDADLDHAVEVATRAQKEWAKF
SLAKRTAIMFKMRELVLAHQDEMARLIVEEHGKNYSDAVGEIQRGRETLDFATAINLALK
GEFSYDIATGVDIHTLRQPVGVVAGICPFNFPTMVPMWMHPVAIATGNAFILKPASATPS
AALLTAELYKEAGLPDGVFNVVSGNRTMVTKVLEHPGIHAISFVGSTPVAHIVQDTGVSH
GKRVQALGGANNHAIVMPDSDLDFAAQHLSAAAFGAAGERCMALPVVVAVGGCGPDLAQR
VKAHAEKIKVGYGMDEGVEMGPVIDAKSKEFIIGLINEGESKGGEVVLDGRDLVIPGHEK
GHFVGPTIVDNVPLDSDLYREEVFGPVLSIVHAETYEEAIEIVNSSPFGNGSAIFTNDGG
VARRFELDVEAGMVGINVPIPTPVAYYSFGGWKESLLGDTHIHGPEGVRFYTRAKAVTSR
WPSEKTFAATMSFQREE
NT seq
1494 nt
NT seq
+upstream
nt +downstream
nt
atgaagacgctgtcccactggatcgacggcaagtactacgagggcacccccatcgggcgc
ttcccggtggagaaccccggcaccggcgaggtggagaaggagctgctgcaggcctccgac
gccgacctcgatcacgccgtcgaggtcgccacccgcgcccagaaggagtgggccaagttc
tccctggccaagcgcaccgccatcatgttcaagatgcgcgagctcgtcctggcccaccag
gacgagatggcccgtctgatcgtcgaggagcacggcaagaactactccgacgcggtcggc
gagatccagcgcggccgcgagaccctcgacttcgccacggccatcaacctggccctcaag
ggcgagttctcctacgacatcgccaccggcgtcgacatccacaccctgcgccagcccgtg
ggcgtggtcgccgggatctgccccttcaacttccccaccatggtgcccatgtggatgcac
ccggtggccatcgccaccggcaacgccttcatcctcaagccggcctcggccaccccctcg
gccgcgctgctgaccgccgagctctacaaggaggccggccttcccgacggcgtgttcaac
gtcgtctccggcaaccgcaccatggtcaccaaggtcctggagcaccccggcatccacgcc
atctccttcgtgggctccaccccggtggcccacatcgtccaggacaccggcgtgtcccac
ggcaagcgcgtccaggcgctgggcggggccaacaaccacgccatcgtcatgcccgactcc
gacctcgacttcgccgcccagcacctgtccgccgcggccttcggcgccgccggcgagcgc
tgcatggcccttccggtggtcgtggccgtgggcggctgcggaccggacctggcccagcgc
gtcaaggcccacgccgagaagatcaaggtcggctacggcatggatgagggcgtggagatg
ggcccggtcatcgacgccaagtccaaggagttcatcatcggcctcatcaacgagggcgag
tccaagggcggggaggtcgtcctcgacgggcgcgacctggtgatccccggccacgagaag
gggcacttcgtcggccccaccatcgtggacaacgtccccctggactccgacctctaccgc
gaggaggtcttcggcccggtgctgtccatcgtgcacgccgagacctacgaggaggccatc
gagatcgtcaactcctcgcccttcggcaacggctcggccatcttcaccaacgacggcggc
gtggcccgccgcttcgagctggacgtcgaggccggcatggtgggcatcaacgtgcccatc
cccacgccggtggcctactactccttcggcggctggaaggagtcgctgctgggcgacacc
cacatccacggccccgagggcgtgcgcttctacacccgggccaaggccgtgacctcccgc
tggccctcggagaagaccttcgcggccaccatgtcattccagcgcgaggagtga
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