Actinomyces slackii: NCTC11923_01545
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Entry
NCTC11923_01545 CDS
T06783
Symbol
leuC
Name
(GenBank) 3-isopropylmalate dehydratase large subunit
KO
K01703
3-isopropylmalate/(R)-2-methylmalate dehydratase large subunit [EC:
4.2.1.33
4.2.1.35
]
Organism
asla
Actinomyces slackii
Pathway
asla00290
Valine, leucine and isoleucine biosynthesis
asla00660
C5-Branched dibasic acid metabolism
asla01100
Metabolic pathways
asla01110
Biosynthesis of secondary metabolites
asla01210
2-Oxocarboxylic acid metabolism
asla01230
Biosynthesis of amino acids
Module
asla_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
asla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NCTC11923_01545 (leuC)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NCTC11923_01545 (leuC)
Enzymes [BR:
asla01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.33 3-isopropylmalate dehydratase
NCTC11923_01545 (leuC)
4.2.1.35 (R)-2-methylmalate dehydratase
NCTC11923_01545 (leuC)
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Motif
Pfam:
Aconitase
Motif
Other DBs
NCBI-ProteinID:
VEG74896
UniProt:
A0A3S4WKI8
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Position
1:1839816..1841270
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AA seq
484 aa
AA seq
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MGMTLAEKVWRDHVVSQGADGAPDLLYIDLHLVHEVTSPQAFEGLRLAGRQVRRPDLTLA
TEDHNTPTLDIDLPIADVTSRAQIETLRANCAEFGVRLHSLGDADQGIVHAVGPQLGLTQ
PGMTVVCGDSHTSTHGAFGALAFGIGTSQVEHVLATQTLPIAPFKTMSVTIDGDLPAGSG
AKDIILAIIAKIGTNGAQGHVIEYRGRAIEQLSMEARMTICNMSIEGGARAGMIAPDQTT
LDYLAGRPHAPEGADWDAAVEYWMSLRTDEDAVFDTEVVLKAADIEPFVTWGTNPGQGLP
ISATVPVPEEIADETQRRAAERALEYMDLTPGMPLRDIRVDTVFLGSCTNGRIEDLRAAA
EVLRGRTKAEGLRMLVVPASARVRLQAEDEGLDRVFTDFGAEWRNAGCSMCLAMNPDKLS
PGERAASTSNRNFEGRQGTGGRTHLVSPVVAAATAVRGTLSTPADLPPLDGQGRGADRPA
PVPA
NT seq
1455 nt
NT seq
+upstream
nt +downstream
nt
atgggcatgaccctggccgagaaggtctggcgcgatcacgtagtctcccagggggccgac
ggcgctcccgacctgctctacatcgacctgcaccttgtccacgaggtcaccagcccccag
gccttcgagggcctgcgcctggccggccgtcaggtccgccgccccgacctgaccctggcc
accgaggaccacaacacccccaccctggacatcgacctgcccatcgccgatgtcaccagc
cgcgcgcagatcgagaccctgcgggccaactgcgccgagttcggggtgcgcctgcactcc
ctgggggacgccgatcagggcatcgtccacgccgtgggcccccagctggggctgacccag
ccgggcatgaccgtggtgtgcggagactcccacacctccactcacggggcgttcggggcc
ctggccttcgggatcggcacctcgcaggtcgagcacgtcctggccacccagaccctgccc
atcgcccccttcaagacgatgagcgtgaccatcgacggcgatctgcccgccggctcgggc
gccaaggacatcatcctggccatcatcgccaagatcggcaccaacggcgcccagggccac
gtcatcgagtatcgcggccgggccatcgagcagctctcgatggaggcccgcatgacgatc
tgcaacatgagcatcgagggcggggccagggccggcatgatcgccccggaccagaccact
ctcgactacctggccgggcgcccccacgcccccgagggcgccgactgggacgccgccgtc
gagtactggatgagcctgcgcaccgatgaggacgcggtcttcgataccgaggtcgtcctc
aaagccgccgacatcgagcccttcgtcacctggggcaccaaccccggtcagggcctgccg
atctcggccaccgtgcccgttcccgaggagatcgccgacgagacccagcgccgtgccgcc
gagcgcgccctggagtacatggacctgacccccggcatgcccctgcgcgacatccgggtc
gacaccgtcttcctgggctcgtgcaccaatgggcgcatcgaggacctgcgcgccgccgcc
gaggtcctgcgcgggcgcaccaaggcggagggcctgcgcatgctcgtggtccccgcctcc
gcccgcgtgcgcctccaggccgaggacgagggcctggaccgggtcttcaccgacttcggg
gccgagtggcgcaacgccggctgctccatgtgcctggccatgaaccccgacaagctcagc
cccggtgagcgagccgcctcgacctccaaccgcaacttcgaggggcgccagggcaccggc
gggcgcacccacctggtctcgcccgtggtggccgcggcgaccgccgtgcgcggcaccctg
tccacccctgccgacctccccccgctggacgggcaggggcgcggcgccgaccgcccggcc
cccgttcccgcctga
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