Actinomyces slackii: NCTC11923_01666
Help
Entry
NCTC11923_01666 CDS
T06783
Symbol
leuA_1
Name
(GenBank) 2-isopropylmalate synthase
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
asla
Actinomyces slackii
Pathway
asla00290
Valine, leucine and isoleucine biosynthesis
asla00620
Pyruvate metabolism
asla01100
Metabolic pathways
asla01110
Biosynthesis of secondary metabolites
asla01210
2-Oxocarboxylic acid metabolism
asla01230
Biosynthesis of amino acids
Module
asla_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
asla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
NCTC11923_01666 (leuA_1)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NCTC11923_01666 (leuA_1)
Enzymes [BR:
asla01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
NCTC11923_01666 (leuA_1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HMGL-like
IPMS_D2
LeuA_dimer
NblA
Motif
Other DBs
NCBI-ProteinID:
VEG75014
UniProt:
A0A448KDJ7
LinkDB
All DBs
Position
1:1977493..1979286
Genome browser
AA seq
597 aa
AA seq
DB search
MRTAPPAPQQPSGMPYAKYLPFVETLATDLPDRTWPTRRITQAPRWLSTDLRDGNQSLIE
PMGPAAKRAIFDLLVGMGFKEIEIGFPAASQTDYDFVRSLVDDDAIPADVTISVLTQSRG
DLIDRTLDACVGIPRATIHLYNAVAPLFRDVVFRMDRGQVRDLAVEGTRQVMARAEKVLG
EETIVGFEYSPEIFVDTEREYALEVCSAVMDVWEPGQGREIILNLPATVERATPNVYADQ
IEWMSRNLPHREHVCLSLHNHNDRGSGVAATELGLLAGGQRVEGCLFGHGERTGNVDLVT
LALNLFSQGVDPMLDISDIDHIRRTVEQATGMDVPPRTPYSGDLVYTSFSGSHQDAIKKG
FAARAAKVQAQRDQGLDEAAAETAVPWQMPYLPIDPHDVGRSYEAVVRVNSQSGKGGVAY
LLGATRKLDLPRRLQIEFSRIVQRHTDTYGGEVDAMTLWRIFADEYLPAHGAHDSEGLDG
LEPWGRYELAGATLTSAGSGQDSELTVTIRDSGQETTLTAQGSGPVDAFVTALETTGIQV
RILDYAEHALSQGRDAQAASYVECEVGGQVLWGVGIDASITTASFKAIISAVNRALR
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgcgcaccgcaccccccgcacctcagcagccctccggcatgccctacgccaagtacctc
cccttcgtcgagaccctcgccacggacctgccggaccgcacctggcccactcgtcgcatc
acccaggccccccgctggctgtccaccgacctgcgcgacggcaaccagtccctcatcgag
cccatggggccggccgccaagcgcgccatcttcgacctgctcgtgggcatgggcttcaag
gagatcgagatcggcttcccggccgcctcccagaccgactacgacttcgtgcgctccctg
gtcgatgacgacgccatcccggccgacgtcaccatctccgtgctcacccagtcccgcggc
gacctcatcgaccgcaccctggatgcctgcgtgggcatcccgcgggccaccatccacctc
tacaacgccgtggcccccctcttccgcgacgtcgtcttccgcatggaccgcggccaggtc
cgcgacctggccgtcgagggcacccgccaggtcatggcccgagccgagaaggtcctgggg
gaggagacgatcgtcggcttcgagtactccccggagatcttcgtggacaccgagcgcgag
tacgccctggaggtgtgcagcgccgtcatggacgtgtgggagcccggccagggccgcgag
atcatcctcaacctgcccgccacggtcgagcgcgccacccccaatgtctacgccgaccag
atcgagtggatgagccgcaacctgccccaccgcgagcatgtgtgcctgtccctgcacaac
cacaacgaccgcggctcgggcgtggccgccaccgagctgggcctgctggccggcggccag
cgggtcgagggctgcctgttcggccatggcgagcgcaccggcaacgtggacctggtgacc
ctggccctcaacctgttcagccagggagtcgaccccatgctggacatctccgacatcgac
cacatccgccgcaccgtggagcaggccaccggcatggatgtgcccccgcgcaccccctac
tccggcgacctggtctacacctccttctccggctcccaccaggacgccatcaagaaggga
ttcgccgcccgcgccgccaaggtccaggcccagcgcgatcagggcctggatgaggcggcg
gccgagaccgccgtgccctggcagatgccctacctgcccatcgacccccacgatgtgggg
cgctcctacgaggccgtggtgcgcgtcaactcccagtccgggaaggggggcgtggcctac
ctgctgggcgccacccgcaagctcgacctgccgcgccgcctgcagatcgagttctcccgg
atcgtccagcgccacaccgacacctacggcggggaggtggatgccatgaccctgtggcgc
atcttcgccgatgagtacctccccgcccacggcgcccacgactccgagggcctggacggg
ctggagccgtggggccgctacgagttggcgggggcgaccctgacctcggcgggctcgggc
caggactccgagctgacggtcaccatcagggactccggccaggagacgaccctgaccgcg
cagggcagcggccccgtggacgccttcgtcaccgccctggagaccaccggcatccaggtg
cgcatcctggactacgccgagcacgccctgagccaggggcgcgacgcgcaggccgcctcc
tatgtggagtgcgaggtcggtgggcaagtcctgtggggcgtgggcatcgacgcctccatc
accaccgcctccttcaaggccatcatctcggccgtcaaccgcgccctgcgctga
DBGET
integrated database retrieval system