Actinomyces slackii: NCTC11923_02390
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Entry
NCTC11923_02390 CDS
T06783
Symbol
leuB
Name
(GenBank) 3-isopropylmalate dehydrogenase
KO
K00052
3-isopropylmalate dehydrogenase [EC:
1.1.1.85
]
Organism
asla
Actinomyces slackii
Pathway
asla00290
Valine, leucine and isoleucine biosynthesis
asla00660
C5-Branched dibasic acid metabolism
asla01100
Metabolic pathways
asla01110
Biosynthesis of secondary metabolites
asla01210
2-Oxocarboxylic acid metabolism
asla01230
Biosynthesis of amino acids
Module
asla_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
asla00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00660 C5-Branched dibasic acid metabolism
NCTC11923_02390 (leuB)
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
NCTC11923_02390 (leuB)
Enzymes [BR:
asla01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.85 3-isopropylmalate dehydrogenase
NCTC11923_02390 (leuB)
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Motif
Pfam:
Iso_dh
PdxA
FilR1_middle
HGLS
Motif
Other DBs
NCBI-ProteinID:
VEG75715
UniProt:
A0A3S4SGV9
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All DBs
Position
1:complement(2885179..2886222)
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AA seq
347 aa
AA seq
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MTTIDLAVIPGDGIGKEVVPEGLKVLGTALAGSGIELSTTHYDLGAERWHRTGDTLTDED
LEAIKGHDAILLGAVGDPSVPSGVLERGLLLRLRFALDHYVNLRPSKYYPGVPTPLVDPG
EIDFLVVREGTEGLYCGNGGAVRVGTPQEIATEVSVNTAFGVERVVRYAFAKADARPAKH
LTLVHKHNVLVNAGHLWRRTVEAISAEYPEVTIDYAHVDAATIYLVTDPGRFDVIVTDNL
FGDILTDEAGAVTGGIGLAASGNINPDRTFPSMFEPVHGSAPDIAGQGIADPTATISAVA
LMLDHLGHTQEARRVEAAVEADMAARSEGRSRTTSEIGDAIVAALGA
NT seq
1044 nt
NT seq
+upstream
nt +downstream
nt
atgacgacgatcgatctggcagtcatccccggcgacggcatcggcaaggaggtcgtgccc
gagggcctgaaggtcctgggcaccgcgctggccggcagcggcatcgagctgtccaccacg
cactacgacctgggcgccgagcgctggcaccgcaccggggacaccctcaccgatgaggac
ctcgaggccatcaagggccacgacgccatcctgctgggcgccgtcggcgacccctcggtc
ccctccggtgttctggagcgggggctgctgctgcgcctgcgcttcgccctggatcactac
gtcaacctgcgtccctccaagtactacccgggcgtgcccacgcccctggtcgatcccggc
gagatcgacttcctcgtggtgcgcgagggcaccgagggcctgtactgcggcaatggggga
gcggtgcgcgtgggcaccccccaggagatcgccaccgaggtcagcgtcaacaccgccttc
ggcgtcgagcgcgtggtccgctacgccttcgccaaggccgacgcccgccccgccaagcac
ctgaccctggtccacaagcacaacgtgctggtcaacgccggccacctgtggcgccgcacc
gtcgaggcgatcagcgccgagtaccccgaggtcaccatcgactacgcccacgtcgacgcc
gccaccatctacctggtcaccgacccggggcgcttcgacgtcatcgtcaccgacaacctc
ttcggcgacatcctcaccgacgaggccggcgccgtcaccggcggcatcggcctggccgcc
tcgggcaacatcaaccccgaccggaccttcccctccatgttcgagcccgtccacggctcg
gcccccgacatcgcaggccagggcatcgccgaccccaccgccacgatctccgcggtcgcc
ctcatgctcgaccacctgggccacacccaggaggcccgccgcgtcgaggccgccgtcgag
gccgacatggccgcacgctccgagggccgcagccgcaccaccagcgagatcggcgacgcc
atcgtcgccgccctgggcgcctga
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