Actinomyces slackii: NCTC11923_02551
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Entry
NCTC11923_02551 CDS
T06783
Symbol
rmlB
Name
(GenBank) dTDP-glucose 4,6-dehydratase
KO
K01710
dTDP-glucose 4,6-dehydratase [EC:
4.2.1.46
]
Organism
asla
Actinomyces slackii
Pathway
asla00521
Streptomycin biosynthesis
asla00523
Polyketide sugar unit biosynthesis
asla00525
Acarbose and validamycin biosynthesis
asla00541
Biosynthesis of various nucleotide sugars
asla01100
Metabolic pathways
asla01110
Biosynthesis of secondary metabolites
asla01250
Biosynthesis of nucleotide sugars
Module
asla_M00793
dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:
asla00001
]
09100 Metabolism
09107 Glycan biosynthesis and metabolism
00541 Biosynthesis of various nucleotide sugars
NCTC11923_02551 (rmlB)
09109 Metabolism of terpenoids and polyketides
00523 Polyketide sugar unit biosynthesis
NCTC11923_02551 (rmlB)
01055 Biosynthesis of vancomycin group antibiotics
NCTC11923_02551 (rmlB)
09110 Biosynthesis of other secondary metabolites
00521 Streptomycin biosynthesis
NCTC11923_02551 (rmlB)
00525 Acarbose and validamycin biosynthesis
NCTC11923_02551 (rmlB)
Enzymes [BR:
asla01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.46 dTDP-glucose 4,6-dehydratase
NCTC11923_02551 (rmlB)
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Motif
Pfam:
GDP_Man_Dehyd
Epimerase
NAD_binding_4
3Beta_HSD
RmlD_sub_bind
Polysacc_synt_2
NAD_binding_10
adh_short
Sacchrp_dh_NADP
NmrA
KR
Motif
Other DBs
NCBI-ProteinID:
VEG75873
UniProt:
A0A3S5EMD6
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Position
1:3074834..3075829
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AA seq
331 aa
AA seq
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MHVLITGGAGFIGANFVHQTLRRFPEATVTVLDKLTYAGNQGSLEGLEERATLVVGDIAD
ADTVDPLVAQADVVVHFAAESHNDNSLNDPSPFIRTNLVGTFTLLEAVRRHKTRFHHVST
DEVYGDLELDDPAKFTPETPYNPSSPYSASKAGSDLLVRAWVRSFGIEATISNCSNNYGP
YQHIEKFIPRQITNLIDGVRPKLYGAGQNVRDWIHVLDHNDAVWDIVNKGRIGETYLIGA
NGEKNNKEVVELILELMGHEPDDYDHVNDRPGHDMRYAIDNTKLVQELGWEPRFTDFRSG
LAETIAWYRDNEAWWRPLKAEVEAKYAAQGQ
NT seq
996 nt
NT seq
+upstream
nt +downstream
nt
atgcacgtcctcatcaccggcggcgccgggttcatcggcgccaacttcgtccaccagacc
ctgcgccgcttccccgaggccaccgtcacggtcctggacaagctcacctacgccggcaac
cagggctccctggagggcctggaggagcgcgccaccctcgtggtcggggacatcgccgat
gccgacaccgtcgacccgctggtggcccaggccgacgtcgtcgtccacttcgccgcggag
tcccacaacgacaactccctgaacgacccctcccccttcatccgcaccaacctcgtgggc
accttcaccctcctggaggccgtgcgccgccacaagacgcgcttccaccacgtctccacc
gacgaggtctacggggacctcgagctcgacgaccccgccaagttcacccccgagaccccc
tacaacccctcctccccctactcggcctccaaggccggctcggatctgctcgtgcgcgcc
tgggtgcgctccttcggcatcgaggccacgatctcgaactgctcgaacaactacggcccc
taccagcacatcgagaagttcatcccccgccagatcaccaacctcatcgacggcgtgcgc
cccaagctctacggggccgggcagaacgtgcgcgactggatccacgtcctggaccacaac
gacgccgtgtgggacatcgtgaacaagggccgcatcggcgagacctacctcatcggggcc
aacggtgagaagaacaacaaggaggtcgtcgagctcattctcgagctcatgggccacgag
cccgacgactacgaccatgtcaacgaccgtcccggtcacgacatgcgctacgccatcgac
aacaccaagctcgtccaggagctgggctgggagccccgcttcaccgacttccgctccggc
ctcgctgagaccatcgcctggtaccgggacaacgaggcctggtggcgcccgctcaaggcg
gaggtcgaggcgaagtacgccgcccagggccagtaa
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