KEGG   Actinomyces slackii: NCTC11923_02551
Entry
NCTC11923_02551   CDS       T06783                                 
Symbol
rmlB
Name
(GenBank) dTDP-glucose 4,6-dehydratase
  KO
K01710  dTDP-glucose 4,6-dehydratase [EC:4.2.1.46]
Organism
asla  Actinomyces slackii
Pathway
asla00521  Streptomycin biosynthesis
asla00523  Polyketide sugar unit biosynthesis
asla00525  Acarbose and validamycin biosynthesis
asla00541  Biosynthesis of various nucleotide sugars
asla01100  Metabolic pathways
asla01110  Biosynthesis of secondary metabolites
asla01250  Biosynthesis of nucleotide sugars
Module
asla_M00793  dTDP-L-Rha biosynthesis, Glc-1P => dTDP-L-Rha
Brite
KEGG Orthology (KO) [BR:asla00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00541 Biosynthesis of various nucleotide sugars
    NCTC11923_02551 (rmlB)
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    NCTC11923_02551 (rmlB)
   01055 Biosynthesis of vancomycin group antibiotics
    NCTC11923_02551 (rmlB)
  09110 Biosynthesis of other secondary metabolites
   00521 Streptomycin biosynthesis
    NCTC11923_02551 (rmlB)
   00525 Acarbose and validamycin biosynthesis
    NCTC11923_02551 (rmlB)
Enzymes [BR:asla01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.46  dTDP-glucose 4,6-dehydratase
     NCTC11923_02551 (rmlB)
SSDB
Motif
Pfam: GDP_Man_Dehyd Epimerase NAD_binding_4 3Beta_HSD RmlD_sub_bind Polysacc_synt_2 NAD_binding_10 adh_short Sacchrp_dh_NADP NmrA KR
Other DBs
NCBI-ProteinID: VEG75873
UniProt: A0A3S5EMD6
LinkDB
Position
1:3074834..3075829
AA seq 331 aa
MHVLITGGAGFIGANFVHQTLRRFPEATVTVLDKLTYAGNQGSLEGLEERATLVVGDIAD
ADTVDPLVAQADVVVHFAAESHNDNSLNDPSPFIRTNLVGTFTLLEAVRRHKTRFHHVST
DEVYGDLELDDPAKFTPETPYNPSSPYSASKAGSDLLVRAWVRSFGIEATISNCSNNYGP
YQHIEKFIPRQITNLIDGVRPKLYGAGQNVRDWIHVLDHNDAVWDIVNKGRIGETYLIGA
NGEKNNKEVVELILELMGHEPDDYDHVNDRPGHDMRYAIDNTKLVQELGWEPRFTDFRSG
LAETIAWYRDNEAWWRPLKAEVEAKYAAQGQ
NT seq 996 nt   +upstreamnt  +downstreamnt
atgcacgtcctcatcaccggcggcgccgggttcatcggcgccaacttcgtccaccagacc
ctgcgccgcttccccgaggccaccgtcacggtcctggacaagctcacctacgccggcaac
cagggctccctggagggcctggaggagcgcgccaccctcgtggtcggggacatcgccgat
gccgacaccgtcgacccgctggtggcccaggccgacgtcgtcgtccacttcgccgcggag
tcccacaacgacaactccctgaacgacccctcccccttcatccgcaccaacctcgtgggc
accttcaccctcctggaggccgtgcgccgccacaagacgcgcttccaccacgtctccacc
gacgaggtctacggggacctcgagctcgacgaccccgccaagttcacccccgagaccccc
tacaacccctcctccccctactcggcctccaaggccggctcggatctgctcgtgcgcgcc
tgggtgcgctccttcggcatcgaggccacgatctcgaactgctcgaacaactacggcccc
taccagcacatcgagaagttcatcccccgccagatcaccaacctcatcgacggcgtgcgc
cccaagctctacggggccgggcagaacgtgcgcgactggatccacgtcctggaccacaac
gacgccgtgtgggacatcgtgaacaagggccgcatcggcgagacctacctcatcggggcc
aacggtgagaagaacaacaaggaggtcgtcgagctcattctcgagctcatgggccacgag
cccgacgactacgaccatgtcaacgaccgtcccggtcacgacatgcgctacgccatcgac
aacaccaagctcgtccaggagctgggctgggagccccgcttcaccgacttccgctccggc
ctcgctgagaccatcgcctggtaccgggacaacgaggcctggtggcgcccgctcaaggcg
gaggtcgaggcgaagtacgccgcccagggccagtaa

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