Aeromonas schubertii: WL1483_3647
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Entry
WL1483_3647 CDS
T04186
Symbol
thrA
Name
(GenBank) bifunctional aspartokinase I/homoserine dehydrogenase I
KO
K12524
bifunctional aspartokinase / homoserine dehydrogenase 1 [EC:
2.7.2.4
1.1.1.3
]
Organism
asr
Aeromonas schubertii
Pathway
asr00260
Glycine, serine and threonine metabolism
asr00261
Monobactam biosynthesis
asr00270
Cysteine and methionine metabolism
asr00300
Lysine biosynthesis
asr01100
Metabolic pathways
asr01110
Biosynthesis of secondary metabolites
asr01120
Microbial metabolism in diverse environments
asr01230
Biosynthesis of amino acids
Module
asr_M00016
Lysine biosynthesis, succinyl-DAP pathway, aspartate => lysine
asr_M00017
Methionine biosynthesis, aspartate => homoserine => methionine
asr_M00018
Threonine biosynthesis, aspartate => homoserine => threonine
Brite
KEGG Orthology (KO) [BR:
asr00001
]
09100 Metabolism
09105 Amino acid metabolism
00260 Glycine, serine and threonine metabolism
WL1483_3647 (thrA)
00270 Cysteine and methionine metabolism
WL1483_3647 (thrA)
00300 Lysine biosynthesis
WL1483_3647 (thrA)
09110 Biosynthesis of other secondary metabolites
00261 Monobactam biosynthesis
WL1483_3647 (thrA)
Enzymes [BR:
asr01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.3 homoserine dehydrogenase
WL1483_3647 (thrA)
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.2 Phosphotransferases with a carboxy group as acceptor
2.7.2.4 aspartate kinase
WL1483_3647 (thrA)
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Gene cluster
GFIT
Motif
Pfam:
Homoserine_dh
AA_kinase
ACT_9
NAD_binding_3
ACT_7
ACT
Motif
Other DBs
NCBI-ProteinID:
ALP43066
UniProt:
A0A0S2SMW9
LinkDB
All DBs
Position
complement(3093815..3096274)
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AA seq
819 aa
AA seq
DB search
MRVLKFGGSSLADPERFLRAAEIAINTHSQSQVALVLSAPAKVTNHLVALVEQTSRGMDA
SQTLSDIRAIFERVLAGIKSACPALDDASLKARLDEELGSVERMMRGIALLGQCPDNVQA
RILSRGENLSISFMTGLLQARGIETGFICPEQLLVTDGNFLEAHVNIEASRQRFAAAGLD
NQRFYLMPGFTGGNDKGETVLLGRNGSDYSAAVLAACVDAECCEIWTDVEGCYSCDPRLV
PDAYLLKTLSYKEAMELSYFGAKVLHPKTVAPVAQFQIPCLIKNSFNPQGPGTLIGPDSG
DDGLKVKAISDLSGMSMFNVSGPGMKGMVGMAGRIFAAVSRAGVSIVLITQSSSEYSVSF
CIHSYDEEKTRKVLEREFALEFKNQLLEPLEAVSNLAIISLIGDGMRTSKGMAARFFTSL
AQASINIVAIAQGSSERSISAVVRAGKVAEAIKACHQNFFGSQQFIDLFMVGVGGVGEAL
VEQIRRQQPVLAEQGIGLRVVALANSRQMVSCPDGLKLDNWKAQLAEGRGSFTLEEVKRL
VEESHIINPVIVDCTSSEAVAAQYADFLAAGFHVVTPNKKANTGSMDYYKALRRTAQQTR
RKFLYETNVGAGLPVIENLQNLIKAGDRLRAFDGILSGSLSFIFGKLDEGMAFSEATKIA
RGNGFTEPDPRDDLNGMDVARKLLILAREAGMPLELADVQVEQALPPGFDVSGDVDSFMA
RLPEADGWFRDQFAAAQAEGKVLRYVGSIEGGKCKVAIKAVGPDEPLFKVKDGENALAFF
SSYYQPIPLVLRGYGAGADVTAAGVFADILRTQNWQQEI
NT seq
2460 nt
NT seq
+upstream
nt +downstream
nt
atgcgagtgttgaagtttggtgggtccagtctggcggatcccgagcgtttcctgcgggcc
gccgaaatcgccattaacacccatagccagtcccaggtggccctggtactgtcggccccg
gccaaggtgaccaaccacctggtagccctggtcgagcagaccagccgcggcatggacgcg
agccaaaccctgagcgatatccgcgccatcttcgagcgggtactggccggcatcaagagc
gcctgcccggcgctggatgacgccagcctcaaggcccgtctggacgaggagctcggcagt
gtcgagcgcatgatgcgcggcatcgccctgctcggtcagtgcccggacaacgtccaggcc
cgtatcctgagccgtggcgagaacctctccatctccttcatgaccggcctcttgcaggcg
cgcggcatcgagaccggcttcatctgccccgagcagctgctggtgaccgacggcaacttc
ctcgaggcccacgtcaacatcgaggcctcccgccagcgctttgccgcggccgggctcgat
aaccagcgcttctacctgatgccgggcttcaccggcggcaacgacaagggcgagactgtg
ctgctcggtcgcaacggctccgactactcggccgccgtgctggccgcctgtgtcgacgcc
gagtgctgcgagatctggaccgacgtggagggctgctacagctgtgatccgcgcctggtg
ccggacgcctacctgctgaaaaccctctcctacaaggaggcgatggagctctcttacttc
ggcgccaaggtgctgcacccgaaaaccgtcgccccggtggcccagttccagatcccgtgt
ctgattaaaaacagcttcaacccccagggccccggcaccctgatcggccccgacagcggt
gacgatggcctcaaggtcaaagccatctcggatctctcgggcatgagcatgttcaacgtc
tccggccccggcatgaagggcatggtcggcatggccggccgcatcttcgccgccgtctcg
cgcgccggggtcagcatagtgctcatcacccagtcatcctccgagtacagcgtcagcttc
tgtatccacagctacgacgaagagaagacccgcaaggtgctcgagcgcgagttcgcgctg
gagttcaaaaaccagctgctcgagcccctcgaggcggtgagcaacctggccatcatctcg
ctgatcggtgacggcatgcgcaccagcaaaggcatggcggcgcgcttctttacctccctg
gcccaggcctccatcaacatcgtcgccatcgcccagggctcgagcgagcgctccatctcc
gccgtggtgcgcgccggcaaggtggccgaggccatcaaggcctgccaccagaacttcttc
ggcagccagcagtttatcgatctcttcatggttggcgtgggcggcgtcggcgaggccctg
gtcgagcagatccgccgccagcagccggtgctggccgagcagggcataggcctgcgcgtc
gtggcgctggccaacagccgccagatggtgagctgccccgatggcctcaagctcgacaac
tggaaggcccagctcgccgaggggcgtggcagcttcaccctggaagaggtcaagcgcctg
gtggaagagagccacatcatcaacccggtgatcgtcgactgcacctcgagcgaagccgtg
gccgcccaatacgccgacttcctggccgccggtttccacgtggtgaccccgaacaagaag
gccaacaccggctccatggattactacaaggccctgcgccgcaccgcccagcagacccgc
cgcaagttcctctacgagaccaacgtgggcgccggcctgccggtcatcgagaacctgcaa
aacctcatcaaggcgggcgatcgcctgcgcgccttcgacggcatactgtccggctcgctc
tcctttatcttcggcaagctcgacgagggcatggcctttagcgaggcgaccaagatcgcc
cgtggcaacggcttcaccgagccggatccgcgcgatgacttaaacggcatggacgtggcg
cgcaagctgctcattctggcccgcgaggctggcatgcccctcgagcttgccgatgtgcag
gtcgagcaggccctgccgcccggcttcgatgtgagcggcgatgtggactccttcatggcc
cgcctgcccgaggctgacggctggttccgcgaccagttcgccgcggcccaggccgagggc
aaggtgctgcgttacgtgggctccatcgaggggggcaagtgcaaggtcgccatcaaggcg
gtcggcccggacgagccgctcttcaaagtcaaggacggtgagaacgcgctcgccttcttc
tcgagctactaccagcccatccccctggtgctgcgcggctatggcgcgggggcggacgtg
accgccgccggggtgtttgccgacatactgcgcacccagaactggcagcaggagatctga
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