Actinobacillus suis ATCC 33415: ASU1_10380
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Entry
ASU1_10380 CDS
T03246
Name
(GenBank) bifunctional glutamate--cysteine ligase/glutathione synthetase
KO
K01919
glutamate--cysteine ligase [EC:
6.3.2.2
]
Organism
ass
Actinobacillus suis ATCC 33415
Pathway
ass00270
Cysteine and methionine metabolism
ass00480
Glutathione metabolism
ass01100
Metabolic pathways
ass01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
ass00001
]
09100 Metabolism
09105 Amino acid metabolism
00270 Cysteine and methionine metabolism
ASU1_10380
09106 Metabolism of other amino acids
00480 Glutathione metabolism
ASU1_10380
Enzymes [BR:
ass01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.2 glutamate---cysteine ligase
ASU1_10380
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Gene cluster
GFIT
Motif
Pfam:
Glu_cys_ligase
ATP-grasp_6
RimK
ATP-grasp_3
ATPgrasp_ST
GARS_A
Dala_Dala_lig_C
Motif
Other DBs
NCBI-ProteinID:
AIJ32331
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Position
complement(2281855..2284128)
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AA seq
757 aa
AA seq
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MKLQQLIKTHQLGLLFQQGKFGIEKESQRIDNQGNIVTTAHPSVFGNRSYHPYIQTDFAE
SQLELITPPNDKLEDTYRWLSAIHEVTLRSLPDDEYIFPFSMPAGLPPESEIKEAQLDNE
WDVKYREHLSAIYGKYKQMVSGIHYNFQISDEFVESAFALQTEYSDKIAFRNALYMKLAN
NFLRYQWILVYLLAATPTVEAQYFGENRPLAEGQLVRSLRSSPYGYVNAPHVVINHDSLQ
EYVESLEHFVANGDLLAEKEFYSNVRLRGAKKARELLEKGVKYAEFRLFDLNPFSPYGIE
LADAKFIHLFLLAMLWIDETSGQKEVELGKQKLYQVALEDPRSHTVFQAEGEAILNLMLA
MLEDLSVPQSEKELLQQKLAQFADPSQTVNGRLLAAIEQAGSYKALGAQLAQQYKAQAFE
RFYAISAFDNMELSTQALLFDATQQGLQIELLDENDQFLALKFGDHLEYVKNGNMTSHDQ
YISPLIMENKVVTKKVLAKAGFNVPKSVEFTSVEQAVAHYPLFEGKAVVIKPKSTNYGLG
ITIFQQGVTDKADFAKAIEIAFREDKEVMVEDYLVGTEYRFFVLGDETLAVLLRVPANVK
GDGIHTVRELVDAKNSDPLRGDGSRSPLKKIALGDIELLQLKEQGLTPDSIPAEGQIVQL
RANSNISTGGDSIDMTDQMHDSYKQLAVGIAKAMGAKVCGVDLIIPDLTKAAEPSLRSWG
VIEANFNPMMMMHIFPYQGKSRRLTKAVLKMLFPELP
NT seq
2274 nt
NT seq
+upstream
nt +downstream
nt
atgaaattacaacaactaattaaaactcatcaactcggtttgctgtttcaacaaggcaaa
ttcggcattgaaaaagaaagccaacgtattgataatcaagggaatattgttactactgct
catcctagcgtttttggtaaccgcagttatcacccatatattcaaaccgattttgcagaa
agccaacttgagctaatcacaccgccaaacgataaattggaagacacatatcgttggcta
tcggctattcacgaggtaacgttacgttcattacctgatgatgaatatattttcccattc
agtatgcctgccggtttaccaccggaatccgagatcaaagaagcacaattagataacgaa
tgggatgtgaaatatcgtgaacacctttctgccatttatggcaaatacaaacagatggtg
agcggtattcactacaatttccagatttctgacgagtttgtcgagagcgcttttgcgtta
caaacggaatacagtgataaaattgcgttccgcaatgcgttatatatgaaattagccaat
aactttttacgttatcaatggattcttgtctatttgcttgctgcaacaccaaccgtagaa
gcgcaatattttggcgaaaatcgaccgcttgcagaaggacaattagtgcgtagtttacgc
tctagcccgtatggctatgtaaatgcgcctcatgtagtaatcaatcacgatagcttgcaa
gaatatgttgaatcattagaacattttgtggcaaacggtgatttattagcggaaaaagaa
ttctattcaaacgtacgtttacgtggcgcgaaaaaagcacgtgaattacttgaaaaaggg
gttaaatatgcggaattccgtttatttgatctcaacccgttctcgccttacggtatcgag
ctcgccgatgccaaatttattcatctgttcttacttgctatgttatggatagatgaaaca
agcggtcaaaaagaagtcgaacttggtaaacaaaaactataccaagttgcacttgaagat
cctcgttcgcacactgtattccaagcagagggtgaagctatccttaacctaatgctggca
atgttagaagatctttcagtgccacaaagcgagaaagagttattacaacaaaaactagct
caatttgctgatccaagccaaacggtaaacggtcgtttattagcagcaattgaacaagcc
ggcagctataaagcactcggtgcacaacttgctcaacaatataaagcacaagcgttcgag
cgtttttatgcgatttccgctttcgataatatggagctttctacacaggctttattattt
gatgcgacccaacaaggcttacagatcgaattgctggatgaaaacgatcagttccttgca
ctcaaattcggtgatcatctcgaatatgtaaaaaacggcaatatgaccagtcacgatcag
tacatttcgccattaattatggaaaataaagtcgtgaccaaaaaagtgttggcgaaagcc
ggttttaatgtgccgaaaagcgttgaatttacctcggtagaacaagcggtggcgcactat
ccgttatttgaaggtaaagcggtggtgattaagccgaaatcgaccaattacggtttgggc
attacgattttccaacaaggcgtaacggataaagccgattttgccaaagcgattgaaatt
gcgttccgtgaagataaagaagtgatggtggaagactatttagtcggtaccgaatatcgt
ttctttgtgctaggtgatgaaacactggcggtattgttacgtgtaccggcgaatgtaaaa
ggtgacggcatacatacggtgcgtgaattggtggacgcaaaaaacagtgatccgctacga
ggcgacggctctcgttcgccattgaaaaaaattgccctaggtgacattgaattgcttcag
ctcaaagaacaaggtttaacacctgattcaattccggctgaaggacaaattgtacaatta
cgtgccaactctaatattagtaccggtggcgattcaattgatatgaccgatcaaatgcac
gacagctataaacaattagcagtcggtattgccaaagcgatgggggcaaaagtctgcggt
gtggatttaatcattccggatttaaccaaagcagccgagccgtctctgcgttcatggggc
gtgattgaagcaaattttaatccgatgatgatgatgcatattttcccttaccaaggaaaa
tctcgccgcttaaccaaggccgtgttaaaaatgctgttcccagaactgccttaa
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