KEGG   Antennarius striatus (striated frogfish): 137588044
Entry
137588044         CDS       T10427                                 
Symbol
erbb2
Name
(RefSeq) receptor tyrosine-protein kinase erbB-2
  KO
K05083  receptor tyrosine-protein kinase erbB-2 [EC:2.7.10.1]
Organism
astr  Antennarius striatus (striated frogfish)
Pathway
astr04010  MAPK signaling pathway
astr04012  ErbB signaling pathway
astr04020  Calcium signaling pathway
astr04510  Focal adhesion
astr04520  Adherens junction
astr04530  Tight junction
Brite
KEGG Orthology (KO) [BR:astr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    137588044 (erbb2)
   04012 ErbB signaling pathway
    137588044 (erbb2)
   04020 Calcium signaling pathway
    137588044 (erbb2)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    137588044 (erbb2)
   04520 Adherens junction
    137588044 (erbb2)
   04530 Tight junction
    137588044 (erbb2)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:astr01001]
    137588044 (erbb2)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:astr04147]
    137588044 (erbb2)
   04090 CD molecules [BR:astr04090]
    137588044 (erbb2)
Enzymes [BR:astr01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.1  receptor protein-tyrosine kinase
     137588044 (erbb2)
Protein kinases [BR:astr01001]
 Receptor tyrosine kinases (RTK)
  EGFR family [OT]
   137588044 (erbb2)
Exosome [BR:astr04147]
 Exosomal proteins
  Exosomal proteins of breast cancer cells
   137588044 (erbb2)
CD molecules [BR:astr04090]
 Proteins
  137588044 (erbb2)
SSDB
Motif
Pfam: PK_Tyr_Ser-Thr Recep_L_domain GF_recep_IV Pkinase Furin-like TM_ErbB1 ABC1 Tcell_CD4_C Haspin_kinase APH Kinase-like
Other DBs
NCBI-GeneID: 137588044
NCBI-ProteinID: XP_068160882
LinkDB
Position
21:9768999..9792098
AA seq 1300 aa
MEAARSLLFVGAVLLGVTGALGREVCLGTEMKLALPSSLENHYETLRLLYTGCQVVHGNL
EITHLHGTPDLSFLQGIVEVQGYVLVAHVSVSLVPLDSLRIIRGSQLYNSSYALAALDNT
MSGRGLQTLRLRSLTEILLGGVYIWGNPHLCFPDPQEIVWRDTLDENNIHAKRHRLQPRA
SNCPDCSSVCGKSCWGETDQDCQALTRIKCASGCRRCKGPLPNDCCHMQCAAGCTGPKDS
DCLACRHFNDSGVCNENCPQPTIYDPVTFQTKPNPNKKFNFGATCVKTCPYNYLPMDVAC
TLVCPIATQEVTITHPDGSETQKCEKCEGDCPKVCYGLGIDSLGVMDYHGITMVTSSNVE
QFNKCKKIFGSLAFLPQSFTRDLVSNTSGLTLEQLRAFKNLEEITGYLYIDAWPDEWTNL
SVFENLKVIRGKMLYKGVFSLAVQNLHIQSLGLRSLRSVSGGLVLLHNNSQLCYTSSLPW
EGLLHPTQGPHRIVSKNQDPQICEAEGHICHPLCEGGCWGPGPSQCVSCSAFQRGTECVE
QCDIYQGSVREFADGSRCVVCHSECQPLNGSASCYGPGADHCAECLKFQDGDFCVDHCPS
GVKEDQQTVWKYSNDTGHCLPCNVNCTLSCTVMDNRGCPVDTRTGPGTTIAAAVGGVVLF
FILLALLVFYLRRQKKLKRKETMRRILQEHELVEPLTPSGASPNQAQMRILKETELKKLR
VLGAGAFGTVYKGVWAPDGENVKIPVAIKVLRENTSPRANKEILDEAYVMAGVASPYVCR
LLGICLTSTVQLVTQLMPFGCLLDYVRENKDRIGSQYLLNWCVQIAKGMSYLEDVRLVHR
DLAARNVLVRNPNHVKITDFGLARLLDIDETEYHADGGKVPIKWMALESILHRKFTHQSD
VWSYGVTVWELMTFGAKPYDMIPAREIPDVLEEGERLPQPLICTIDVYMIMVKCWMIDPD
SRPRFKDLVNDFSAMARDPPRYVVIQNDDQMSLSSPVDSRFYRMLLEEEGNNMRELLDAE
KYLVPQPNAFPRTQGEGAPSNGPSRHQSYRSRDQGLDVEPSVINGPRSMYSSLSTLSRSQ
YPTLPLGASTSNGLWTSQYPTLDRSPSAGGQSDNVFLDGPSDDPSLPPASPGRYCKDPTY
SNGSQCDLETDGPNGFSHPQNLHHSLPRRTHGHNQNRAMPEYVNQEIQNFRPGVPERPTT
LPRKGSRTERRVPNGLSSGHSVENPGYLVPVNTSTSPAFDNPYYLDLVPKGKAVAGVPAM
DSPEAQDMDGGVPRHVNGFMTPTAENPEYLGLADTWTGYT
NT seq 3903 nt   +upstreamnt  +downstreamnt
atggaggcggcgagaagtttgctgttcgtcggggccgtgctgctcggagtgacgggcgcg
ttgggcagagaagtgtgcctgggtacagaaatgaagctggccctgccttccagcctggaa
aatcattatgaaacgttgaggctgctctacacaggatgccaggttgttcacggcaacctg
gagattacacaccttcatgggacccctgacctctccttcctacagggtatcgtggaagtg
cagggctatgtgctcgtagcccatgtgtcggtgagtctggtgcctttagacagccttcgg
atcattagaggcagccagttgtacaactccagctacgccttggctgcgctagataacacg
atgagtggacgggggctccagactctccggcttcgtagcctcacagagatcctgttgggt
ggggtgtatatttggggcaacccccatctgtgcttcccagacccccaggaaattgtttgg
agggacactttggacgagaataacatccatgccaagaggcatcgactgcagcctcgggcc
tctaattgtccagattgttcctctgtatgtggcaaaagctgctggggagaaactgatcag
gactgccaggccttgacccgtattaaatgtgcgtccggctgtcggcggtgtaaaggtcct
cttcccaatgattgctgtcacatgcagtgtgctgcaggatgtaccggaccaaaagactca
gactgtctggcctgccgtcacttcaacgacagcggtgtgtgtaatgagaactgtcctcaa
cccaccatctacgaccccgtcacctttcagaccaaacccaacccaaacaagaagttcaac
tttggagccacctgtgtcaagacatgtccttataactatctccctatggatgtggcttgc
accttggtctgtcctatagccacccaggaagttaccatcacccatccggatggaagtgag
acacagaaatgtgagaagtgtgaaggagactgtccaaaagtatgttatggcctgggtatt
gacagcctcggagtaatggattaccatggcattacaatggtgacctcttctaatgtggag
cagttcaacaagtgcaagaagatttttggtagtctggctttcctccctcagagcttcaca
agggaccttgtgagcaacacatcaggcctaaccctggagcagctgagagcctttaagaat
ctagaggagattacaggttatttatatattgatgcctggccagatgagtggactaatctg
agtgtgtttgagaacctgaaggtgatcagaggcaagatgctctacaagggtgttttttca
cttgcagtccagaatctgcacatccagtctcttgggttgcgttcactacgaagtgtcagt
ggaggtttagtcctgctgcacaacaactcccaactgtgctacaccagttctctgccctgg
gagggtctccttcatcccacacagggaccccatcgcattgtcagcaaaaaccaggacccc
cagatctgtgaggcagaggggcatatatgtcacccactgtgtgaggggggctgctggggt
ccagggcccagccagtgtgtgtcctgcagtgctttccaacgtggcactgagtgtgtggag
cagtgcgacatctatcagggatctgtgcgtgaatttgcagatggatctcgatgcgttgtc
tgtcattcagagtgtcaacctctcaatgggtctgcctcctgttacggcccgggtgcagat
cattgtgcagagtgtctaaaatttcaggatggtgacttttgcgtggatcattgtcccagc
ggtgtgaaggaggatcaacagacagtgtggaagtacagtaatgatacaggacactgtcta
ccatgcaacgttaattgcacactgtcttgcaccgtgatggataacagaggttgtccagtt
gatactaggacaggaccaggtacgaccattgcagctgcagtgggtggtgtggtgctcttc
ttcatcctcctggctctgctggtcttctacctgagaagacaaaagaagctgaagaggaag
gagacaatgaggaggatcctgcaagaacatgagctggtggagcctctaacacccagtggt
gcatcgcccaatcaagctcagatgcgcatcctgaaggaaactgaattgaaaaagctcagg
gtcttgggtgcaggggcgtttggaactgtatacaagggagtgtgggcacctgacggggaa
aatgtaaaaattccagtagccattaaggtattgcgagagaacacttcgccaagagccaac
aaagagatcctagatgaggcttatgtgatggcgggagtagccagtccctatgtgtgtcgt
ttgctgggtatatgtctgacctccacggtgcagctggtcactcagctgatgccattcggc
tgcctccttgactacgtcagggagaacaaagatcgcatcggctctcagtatctcctcaac
tggtgtgtccaaatcgctaagggaatgagttacctggaggatgttcggctggtccacaga
gacctggctgcccgcaatgttctggtgaggaacccgaaccatgtgaagatcaccgacttc
ggtctggcccgtctgcttgatatagatgagactgaataccacgctgatggagggaaggtc
ccgattaagtggatggccctcgagtcaattctgcaccggaagttcactcatcagagtgac
gtgtggagctacggggtaaccgtgtgggagctgatgacatttggcgctaaaccctacgac
atgatcccagccagagaaatcccagatgttttagaggaaggagaacggcttccccagcct
ctcatctgcaccattgatgtctacatgattatggtcaaatgttggatgattgacccagac
agccggccacggttcaaagatctggtgaatgatttcagtgccatggccagagatcctccc
cgttatgtagtcattcagaatgatgaccaaatgagtttgtccagcccggtggacagtagg
ttctaccggatgctcctggaagaggaagggaacaacatgagggaactgctggatgctgag
aagtatttggttcctcagccaaacgccttccccaggactcagggagaaggggctccatcc
aatgggccatccagacaccagtcatacaggagcagagatcagggcttagatgtggagccc
tctgtaatcaacggcccccggagtatgtactcctcactgagcactctaagccgaagccag
taccctacactaccattaggagccagcacctccaatggcctgtggacttctcagtaccca
acactggaccgtagcccctcagcaggaggccagtctgataatgttttcttggatggacct
tcagatgacccctcattgccccctgccagtcctgggcgctactgcaaagaccccacctac
tccaatgggagtcagtgtgacctggaaacagacggaccgaacggtttctctcatcctcaa
aaccttcatcactcactacccaggcggactcacggacacaatcaaaatcgcgccatgcca
gaatacgtcaaccaggagattcagaatttcaggccgggggtccctgagcggcccactaca
ttgcctcgcaaaggctccagaacagaaagacgagtccccaatggcctgagctccggtcac
agtgtggaaaacccaggatacctggtccctgtgaacacctccacctctccagcctttgac
aacccctactacctggaccttgtgcctaaaggcaaagctgtagccggcgttccagcaatg
gacagccctgaggcacaagacatggatggaggagttcccaggcatgtgaacgggtttatg
acccccacagcagaaaacccagagtatttgggactcgcggacacctggactggatatacc
tga

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