| Entry |
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| Symbol |
plcb2
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| Name |
(RefSeq) 1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-2
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| KO |
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| Organism |
astr Antennarius striatus (striated frogfish)
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| Pathway |
| astr04070 | Phosphatidylinositol signaling system |
| astr04261 | Adrenergic signaling in cardiomyocytes |
| astr04621 | NOD-like receptor signaling pathway |
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| Module |
| astr_M00130 | Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4 |
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| Brite |
KEGG Orthology (KO) [BR:astr00001]
09100 Metabolism
09101 Carbohydrate metabolism
00562 Inositol phosphate metabolism
137611209 (plcb2)
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
137611209 (plcb2)
04371 Apelin signaling pathway
137611209 (plcb2)
04020 Calcium signaling pathway
137611209 (plcb2)
04070 Phosphatidylinositol signaling system
137611209 (plcb2)
09133 Signaling molecules and interaction
04082 Neuroactive ligand signaling
137611209 (plcb2)
04081 Hormone signaling
137611209 (plcb2)
09140 Cellular Processes
09144 Cellular community - eukaryotes
04540 Gap junction
137611209 (plcb2)
09150 Organismal Systems
09151 Immune system
04621 NOD-like receptor signaling pathway
137611209 (plcb2)
09152 Endocrine system
04912 GnRH signaling pathway
137611209 (plcb2)
04916 Melanogenesis
137611209 (plcb2)
09153 Circulatory system
04261 Adrenergic signaling in cardiomyocytes
137611209 (plcb2)
04270 Vascular smooth muscle contraction
137611209 (plcb2)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:astr04131]
137611209 (plcb2)
Enzymes [BR:astr01000]
3. Hydrolases
3.1 Acting on ester bonds
3.1.4 Phosphoric-diester hydrolases
3.1.4.11 phosphoinositide phospholipase C
137611209 (plcb2)
Membrane trafficking [BR:astr04131]
Exocytosis
Calcium ion-dependent exocytosis
Phospholipases
137611209 (plcb2)
Endocytosis
Macropinocytosis
Phospholipase C
137611209 (plcb2)
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| SSDB |
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| Motif |
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| Other DBs |
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| LinkDB |
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| Position |
17:8915776..8934465
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| AA seq |
1248 aa
MNKKRHFLEPPEVKDYLVKGERFTKWSEDSTKTVPVTMKMDPKGFYVYWINQSKETTFLD
VATIRDTRTGKYAKLPKHSKVRNVFNLDFPDSNHLAKTLTLVSGPDMVNLTYHNFFASKE
KVTQNWANDILAIAYNAARNNSCRQVFLDKMYTCISLHNNKDGKIPVKYIYKMFPADKKR
VENALAAAHLPKGKYDSMKPDVFTESAFKIFFANLCPRPEILEIFTSYSNKPTMTKENFT
KFLNEKQRDSRLNEELFPRLRQDQIKALIDKYEPCTSNSNRSLISPEGLLNFLMGPEMSV
VMQDRLAKCQDMTQPIPHYFIKSSHNTYLTAGQFSGVSSPEMYRQCLLSGCRCLELDCWK
GKPPDEEPIITHGFTMTTEILYKDVIEAIAESAFKTSQYPVILSFENHVDSVKQQEKMAN
YCKTIFGDTLLTEPLDKYPLKPGQQIPSPSELLGKILIKNKKGGHEKPTQPKQKVAVVAD
QTTNTAAPTQDPSTTSQDADNPAPGTQESPEGDVAAEDNEEQEDTEEQDEEKMKTSDEGT
AGQEVTAYEAMSSLVNYIQPNKFISFDNARKKNKSYVVSSFVETKGETMISKTAVEFVEY
NKRQMSRIYPKGTRMDSSNYSPQPFWNVGCQMVALNYQTMDFPMQLNMALFEFNGRTGYL
LKHDVMRRSDKKFDPFCDRIDTVVASTLTIKIYSGQFLSDKNVRTGVEVEVIGLPGDPKK
KFRTKWSPMPNAINPVWNEEPFVFEKILLPEMASLRIVVHEENGKFVGHRIIPLDAIQSG
FHHICLRSESNMPLTLPALFVYIEVKDYIPAAFADFTDALFNPTKGTEKSQKTTKESSSD
YVSPYELPLIVQAVTEKAKKSKDPENAASETKLDVNVNDKSSKSPPQASVQEAKKETENI
SEPPQREGKSPQSPDNTADASETPPESVPPPGDAAPESRNEPMNDTSTNSETTSNDKPGT
DDEELAAEAVPSPESSSPEAAGAEDSPQQPSHGEEPSTVTAEELTTHKNYLKVIKRQERE
MKGVEKKYQKKTEDLMQKYSDSFKAIKKKVSVKKTEGGGNASDNGLKTERVQDQKEKMQQ
ELQVLWTEQYDQLRRKKEQSATERLAKLLEMASERHDSELKTLESEIKENRKKAFSKRSS
SERGKLKKAVSTELLDEAIQSDGEIADDKPLEEDLMKKQAATLEDIKTFSNQLNQEALME
HAQKMRSLPAEVKEAVNVCMGAHFPELVDQAGDKKVECVGVYGDVFLG |
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| NT seq |
3747 nt +upstreamnt +downstreamnt
atgaataagaaaagacacttcctggagcctccagaggtcaaagactacctggtgaaagga
gaaagattcaccaaatggtcagaggactccacaaagaccgttcccgtcaccatgaagatg
gatccgaaaggtttttatgtctactggatcaaccaaagcaaggagaccacattcctggat
gttgctactatcagagacaccagaacaggaaaatatgcaaaacttcccaaacactcaaag
gttcgcaacgtgttcaatctggacttcccagacagcaaccatcttgccaaaactctgacc
ctggtgtcaggtccagacatggtgaacttgacctatcataacttctttgcctctaaggag
aaagtaacgcagaactgggcaaatgatatccttgcgattgcctacaacgctgcgagaaac
aattcgtgcagacaagtcttcctggataaaatgtatacctgcatttctcttcataacaac
aaggatggcaagatcccagtgaaatatatctacaagatgttcccagcggataagaagagg
gtagaaaatgcgttagcagctgctcacctccctaaaggaaagtatgactccatgaagcct
gatgtctttactgagtctgccttcaagatcttttttgcaaatctctgcccccggcctgag
atccttgagatcttcacttcttactccaacaaacccaccatgacaaaagagaacttcacc
aagttcctgaacgagaaacagagggattctcggctcaacgaagaactgtttccacgtctg
cgtcaggaccagatcaaggctctgattgataaatatgaaccctgcacctctaattcaaac
agaagtctgatttctccagaaggtctcctaaacttccttatgggtccagagatgtcagtg
gtcatgcaagacaggctggccaagtgtcaagacatgacccagcccatcccacactacttc
atcaagtcctcccacaacacatatctgacagccggtcagttctccggcgtctcctcacct
gagatgtaccgtcagtgtctgctgtctggctgccgctgcctggagctggactgttggaag
ggcaaacctccagatgaagaacccatcatcacccatggcttcaccatgacgactgagatc
ctctacaaggatgtgattgaggctattgctgagagtgccttcaagacctcacagtatcca
gttattctgtcattcgagaaccacgttgactcggtgaaacagcaggagaagatggcaaac
tactgcaaaaccatatttggtgataccctgctaacagagccgctggataaataccctctg
aagcccggccagcagattccaagcccctctgagctcttgggcaaaatcctcatcaaaaac
aagaagggcggtcatgaaaagccgacacagcctaagcaaaaggttgctgtagttgctgac
caaaccacaaacacagctgcaccaacccaggaccccagcaccacctctcaggatgctgac
aatccagcacccggtacccaggagagcccagagggggatgtagcggcggaggacaacgag
gagcaggaggacacagaggagcaggatgaagagaaaatgaagacatcggatgagggcaca
gctggacaagaggtaacagcatatgaggcaatgtcatccctggttaactacatccagccc
aacaaattcatctcttttgacaacgccagaaagaaaaataagagttatgtcgtctcatct
tttgttgagaccaaaggggagacaatgatttcaaagactgctgttgaatttgttgaatac
aataagaggcagatgagtcggatttaccctaaaggaacgagaatggactcttccaactac
agcccccagcctttctggaatgtaggctgccagatggtggcgctcaactaccagacaatg
gatttccccatgcagctgaacatggctctgtttgaattcaatggcagaactggctacctc
ctcaaacatgatgtaatgcgtcgcagtgacaagaagtttgatccattctgtgacaggatt
gacaccgttgtggcgagcacattgacaataaagatctattccgggcagtttttgtctgat
aagaatgtgagaacaggagtggaggtggaggtgattgggctgccaggggaccccaagaaa
aaatttcgcaccaaatggtccccaatgcccaatgccatcaacccagtgtggaacgaagag
ccttttgtgtttgagaagatcctgcttcctgaaatggcctctttgagaattgtggtccac
gaggagaatggtaaattcgtaggacacaggatcatcccacttgatgcaatccaatcaggt
ttccatcacatctgcctccgcagtgagagcaacatgccactcactttgcctgctcttttt
gtctacattgaagtcaaggattacatccctgcagccttcgcagatttcacagatgcctta
tttaacccaacaaaaggcacagagaagagccaaaagaccacaaaagagtcatcctccgac
tatgtctctccctatgagcttcctcttatagttcaagccgtcacagaaaaggctaagaaa
agtaaagatccagaaaatgctgcatctgaaactaaactggacgtcaatgtcaatgacaaa
tcatctaagtctccaccacaagcaagtgtccaagaagcaaaaaaagagacagagaacata
tcagaacctccacaacgtgaaggaaaatctcctcaatctcctgacaacacagcagatgca
tctgaaacccctcctgaatctgttcctcctcctggagatgcagctccagaaagcaggaat
gaacccatgaatgacaccagcacaaactccgagaccacttcaaatgataaacctgggaca
gatgatgaagagctcgctgctgaggctgttcccagtccagaaagttcatctccagaggcc
gcaggagcagaagactcacctcagcaaccatcacacggtgaagagccttcaacagtgact
gctgaagaactgacaacgcacaagaactatttgaaggtcatcaaacgccaggagagagag
atgaagggagtggaaaagaaatatcagaaaaaaacagaggacctgatgcagaaatactcc
gactctttcaaggctatcaagaagaaggtctcggtgaagaaaacagagggagggggaaac
gcctctgacaatggtttgaagacagagcgggtgcaggatcagaaggagaagatgcagcag
gagctgcaagttctgtggactgaacagtatgatcagctgaggaggaagaaagagcagtct
gctaccgagagactggctaagctgttggagatggcatcagagagacatgacagtgagctg
aagaccctggagagtgaaatcaaagaaaacaggaagaaagcgttctcaaaacgttccagt
tcagagagaggaaagctgaaaaaggcagtgagcacagagctgctggatgaagctattcag
tctgatggagaaattgcagatgacaaacccctggaggaggatctaatgaagaaacaggct
gctacactggaggacatcaagaccttcagtaatcagcttaatcaggaggccctgatggag
catgcacagaaaatgaggtcgttgccagcagaggtgaaggaggccgtcaatgtctgtatg
ggggcccacttccccgaattggtcgatcaggctggagacaagaaggtggagtgtgtgggc
gtctacggagatgtcttcctgggttaa |
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