Acidithiobacillus sulfuriphilus: EC580_006295
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Entry
EC580_006295 CDS
T11327
Name
(GenBank) thiamine pyrophosphate-dependent enzyme
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
asuu Acidithiobacillus sulfuriphilus
Pathway
asuu00010
Glycolysis / Gluconeogenesis
asuu00020
Citrate cycle (TCA cycle)
asuu00620
Pyruvate metabolism
asuu00785
Lipoic acid metabolism
asuu01100
Metabolic pathways
asuu01110
Biosynthesis of secondary metabolites
asuu01120
Microbial metabolism in diverse environments
asuu01200
Carbon metabolism
asuu01210
2-Oxocarboxylic acid metabolism
Module
asuu_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
asuu00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
EC580_006295
00020 Citrate cycle (TCA cycle)
EC580_006295
00620 Pyruvate metabolism
EC580_006295
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
EC580_006295
Enzymes [BR:
asuu01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
EC580_006295
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Transketolase_N
Death_EDAR
Motif
Other DBs
NCBI-ProteinID:
XRI78270
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Position
complement(1235359..1236423)
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AA seq
354 aa
AA seq
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MDRSVMAAMLRDMLLARAFEEQAAQEYAQGNVAGFLHLYPGEEAVAVGVLHAAEPGDYVV
STYREHVHAIVRGVPPRQVMAEIFGKKDGISGGMGGSMHLFDRERRFLGGYAIVGETFPI
AVGAAYAVAYRKLPEAVICFFGDGAVNQGTFHESLNMAALWKLPVLFVCENNHYQIGTEI
HRHSAMVEVHKRACAYGIPAEKVDGMDVLTVHGAARRALERVRAGDGPQFLECETYRYRG
HSMADPGSYRPAVEVNAFVANDPIAAAIHHAEPHYPSAEELQCVGPDCVHRFTEHCCAEG
HLDPAAVEQLRQEVGAIVQDAAAFARQSPAPEMVDVQAAFLRNRRFETLMEDPQ
NT seq
1065 nt
NT seq
+upstream
nt +downstream
nt
atggataggagcgtcatggcagccatgctgcgcgacatgctcctggcccgcgcctttgag
gagcaggcggcgcaggaatacgcccaggggaatgtcgccggcttcctgcatctctacccc
ggcgaggaggcagtggccgtgggcgtgctccacgccgccgaacccggagactatgtggtg
agcacctatcgcgagcatgtgcacgccatcgtccgcggcgttccgccccgccaggtcatg
gcggagatcttcggcaagaaggacggcatcagcggcggcatgggcggctccatgcacctc
ttcgatcgggagcgacgctttctgggcggctacgccattgtcggcgaaacctttcccatt
gccgttggtgcagcctatgccgtggcttaccgcaagctccccgaagcggtgatctgcttt
ttcggcgacggcgcggtcaaccaaggcacctttcacgagtcgctgaacatggccgccctg
tggaagttgccggtgctctttgtctgcgaaaacaaccattatcagatcggcaccgagatc
catcgccattccgccatggtcgaggtccataagcgcgcctgcgcctacggcatccccgcc
gaaaaggtggatgggatggatgtgctgacggtgcatggggcagcgcgccgcgccctggaa
cgggtacgtgcgggcgacgggccgcagttcctggaatgcgagacctatcgctaccggggc
cattccatggcggatccgggttcctaccgtccggccgtggaggtgaacgcctttgtcgcc
aatgaccccattgccgccgccattcaccacgcggaaccgcactaccccagcgccgaggag
ctccagtgcgtcggccccgattgtgtgcaccgcttcaccgagcactgttgcgcggagggg
cacctggacccggcggcggtggaacaactgcggcaggaggtgggcgccatcgtccaggac
gccgccgcctttgcccggcaaagccctgctcccgagatggtggatgtgcaggccgctttc
ctgcgcaatcggcgcttcgagacccttatggaggacccccaatga
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