Acidithiobacillus sulfuriphilus: EC580_012265
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Entry
EC580_012265 CDS
T11327
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
asuu Acidithiobacillus sulfuriphilus
Pathway
asuu00300
Lysine biosynthesis
asuu00550
Peptidoglycan biosynthesis
asuu01100
Metabolic pathways
asuu01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
asuu00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
EC580_012265 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
EC580_012265 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
EC580_012265 (murF)
Enzymes [BR:
asuu01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
EC580_012265 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
AAA_25
Motif
Other DBs
NCBI-ProteinID:
XRI76718
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Position
complement(2491734..2493083)
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AA seq
449 aa
AA seq
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MIRLSLKQIAAITGGSLLPGSDAGLEIVGLATDSRQPLAGELFVALPGQRFDGHEYVAAA
LAQGAAAVLVARPVAAPGVLVADTLVAVQALAAHWRRQFTLPVAAVTGSCGKTTVKEILA
AILAQEGPVLASRGNQNNHIGVPLTLARLGPEHRYAVLEMGMNHAGELALLTRLAQPRLA
LITNAAAAHLEGLGTVAAVAMAKGEILEGLDPQGTAVLNADDPFVEDWAEKAPGEVWRFT
LEDRPARVRGRWEAMGQGGHLELRAPQGEFGLALPLAGRHNGANALAAATAALALGIPIA
TIQRGVATLRPIPGRLQWRSGKAGYRLLDDTYNANPASLEAAMQVLAAQTGRRILILGDM
GELGPAAVAYHRQAGQRARALGIDALLALGPLAAEAAAAFGADAAAFDDLEALLEAVAPL
LDPDCVVLVKGSRAARMERVVAALRMEVA
NT seq
1350 nt
NT seq
+upstream
nt +downstream
nt
atgatccgcctttccttaaaacagatcgccgccattaccggtggcagcctcctgcccggc
agcgacgccggactggagattgtagggctggctacggacagccgtcagccgctagcaggt
gaactctttgtggcgctgccgggtcagcgtttcgacggtcacgaatacgtggcagcggcc
ctggcgcagggggccgctgcggtcctggtggcccgccccgtggcggccccgggggtcctc
gtggccgataccctggtcgccgtgcaagccctggccgcccactggcgccgccagttcacc
ttgccggtggcggccgtcaccggctcctgcggcaagaccacggtcaaggagatcctcgcc
gccattcttgcccaggagggaccggtcctggcgagccgcggtaatcaaaacaaccacatc
ggcgtgcccttgaccctggcgcgactggggccggagcaccgttatgcggttctggaaatg
ggaatgaatcacgccggcgaactggcgctgttgacgcgcctggcgcagccgcggctggca
ttgatcaccaatgcggccgccgcccatctggagggcctggggacggtggccgccgtggcg
atggccaaaggcgagatcctggagggtctggatccgcagggcacggcggtgctcaatgcc
gatgacccctttgtggaggactgggcggaaaaggctcccggcgaggtctggcgcttcact
ctggaggatcggccggcgcgcgtgcgcggccgctgggaggccatggggcagggtggccac
ctggagctgcgggcgccccagggcgagtttggcctcgccctgcccctggcgggtcgccac
aatggcgccaatgccctggcggcggctacggcggccctggccctcggtatccccatcgcc
acgatccagcgcggcgtggccacgttgcggcccattcccggccgtctgcagtggcgtagc
ggtaaggccggttatcgcctcctggacgatacctacaacgccaaccccgcctccctggaa
gcggccatgcaggtcctggccgcccagaccggccgccgcatcctgatcctcggcgacatg
ggcgagttgggacctgcggccgtggcctatcatcggcaggcggggcagcgggcgcgggcc
ctgggcattgacgccctgcttgccctgggccctctggcggcggaagccgctgcggccttt
ggggccgacgccgccgcctttgacgatctggaggccctgctggaggccgttgctccccta
ctggacccggattgcgtggtgctcgtcaaaggctcccgggcggcgcgcatggagcgggtg
gtggcggccttgcgcatggaggtggcctga
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