KEGG   Apodemus sylvaticus (European woodmouse): 127665757
Entry
127665757         CDS       T10613                                 
Symbol
Mapk1
Name
(RefSeq) mitogen-activated protein kinase 1
  KO
K04371  mitogen-activated protein kinase 1/3 [EC:2.7.11.24]
Organism
asyl  Apodemus sylvaticus (European woodmouse)
Pathway
asyl01521  EGFR tyrosine kinase inhibitor resistance
asyl01522  Endocrine resistance
asyl01524  Platinum drug resistance
asyl04010  MAPK signaling pathway
asyl04012  ErbB signaling pathway
asyl04014  Ras signaling pathway
asyl04015  Rap1 signaling pathway
asyl04022  cGMP-PKG signaling pathway
asyl04024  cAMP signaling pathway
asyl04062  Chemokine signaling pathway
asyl04066  HIF-1 signaling pathway
asyl04068  FoxO signaling pathway
asyl04071  Sphingolipid signaling pathway
asyl04072  Phospholipase D signaling pathway
asyl04114  Oocyte meiosis
asyl04140  Autophagy - animal
asyl04148  Efferocytosis
asyl04150  mTOR signaling pathway
asyl04151  PI3K-Akt signaling pathway
asyl04210  Apoptosis
asyl04218  Cellular senescence
asyl04261  Adrenergic signaling in cardiomyocytes
asyl04270  Vascular smooth muscle contraction
asyl04350  TGF-beta signaling pathway
asyl04360  Axon guidance
asyl04370  VEGF signaling pathway
asyl04371  Apelin signaling pathway
asyl04380  Osteoclast differentiation
asyl04510  Focal adhesion
asyl04520  Adherens junction
asyl04540  Gap junction
asyl04550  Signaling pathways regulating pluripotency of stem cells
asyl04611  Platelet activation
asyl04613  Neutrophil extracellular trap formation
asyl04620  Toll-like receptor signaling pathway
asyl04621  NOD-like receptor signaling pathway
asyl04625  C-type lectin receptor signaling pathway
asyl04650  Natural killer cell mediated cytotoxicity
asyl04657  IL-17 signaling pathway
asyl04658  Th1 and Th2 cell differentiation
asyl04659  Th17 cell differentiation
asyl04660  T cell receptor signaling pathway
asyl04662  B cell receptor signaling pathway
asyl04664  Fc epsilon RI signaling pathway
asyl04666  Fc gamma R-mediated phagocytosis
asyl04668  TNF signaling pathway
asyl04713  Circadian entrainment
asyl04720  Long-term potentiation
asyl04722  Neurotrophin signaling pathway
asyl04723  Retrograde endocannabinoid signaling
asyl04724  Glutamatergic synapse
asyl04725  Cholinergic synapse
asyl04726  Serotonergic synapse
asyl04730  Long-term depression
asyl04810  Regulation of actin cytoskeleton
asyl04910  Insulin signaling pathway
asyl04912  GnRH signaling pathway
asyl04914  Progesterone-mediated oocyte maturation
asyl04915  Estrogen signaling pathway
asyl04916  Melanogenesis
asyl04917  Prolactin signaling pathway
asyl04919  Thyroid hormone signaling pathway
asyl04921  Oxytocin signaling pathway
asyl04926  Relaxin signaling pathway
asyl04928  Parathyroid hormone synthesis, secretion and action
asyl04929  GnRH secretion
asyl04930  Type II diabetes mellitus
asyl04933  AGE-RAGE signaling pathway in diabetic complications
asyl04934  Cushing syndrome
asyl04935  Growth hormone synthesis, secretion and action
asyl04960  Aldosterone-regulated sodium reabsorption
asyl05010  Alzheimer disease
asyl05020  Prion disease
asyl05022  Pathways of neurodegeneration - multiple diseases
asyl05034  Alcoholism
asyl05132  Salmonella infection
asyl05133  Pertussis
asyl05135  Yersinia infection
asyl05140  Leishmaniasis
asyl05142  Chagas disease
asyl05145  Toxoplasmosis
asyl05152  Tuberculosis
asyl05160  Hepatitis C
asyl05161  Hepatitis B
asyl05163  Human cytomegalovirus infection
asyl05164  Influenza A
asyl05165  Human papillomavirus infection
asyl05166  Human T-cell leukemia virus 1 infection
asyl05167  Kaposi sarcoma-associated herpesvirus infection
asyl05170  Human immunodeficiency virus 1 infection
asyl05171  Coronavirus disease - COVID-19
asyl05200  Pathways in cancer
asyl05203  Viral carcinogenesis
asyl05205  Proteoglycans in cancer
asyl05206  MicroRNAs in cancer
asyl05207  Chemical carcinogenesis - receptor activation
asyl05208  Chemical carcinogenesis - reactive oxygen species
asyl05210  Colorectal cancer
asyl05211  Renal cell carcinoma
asyl05212  Pancreatic cancer
asyl05213  Endometrial cancer
asyl05214  Glioma
asyl05215  Prostate cancer
asyl05216  Thyroid cancer
asyl05218  Melanoma
asyl05219  Bladder cancer
asyl05220  Chronic myeloid leukemia
asyl05221  Acute myeloid leukemia
asyl05223  Non-small cell lung cancer
asyl05224  Breast cancer
asyl05225  Hepatocellular carcinoma
asyl05226  Gastric cancer
asyl05230  Central carbon metabolism in cancer
asyl05231  Choline metabolism in cancer
asyl05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
asyl05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:asyl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    127665757 (Mapk1)
   04012 ErbB signaling pathway
    127665757 (Mapk1)
   04014 Ras signaling pathway
    127665757 (Mapk1)
   04015 Rap1 signaling pathway
    127665757 (Mapk1)
   04350 TGF-beta signaling pathway
    127665757 (Mapk1)
   04370 VEGF signaling pathway
    127665757 (Mapk1)
   04371 Apelin signaling pathway
    127665757 (Mapk1)
   04668 TNF signaling pathway
    127665757 (Mapk1)
   04066 HIF-1 signaling pathway
    127665757 (Mapk1)
   04068 FoxO signaling pathway
    127665757 (Mapk1)
   04072 Phospholipase D signaling pathway
    127665757 (Mapk1)
   04071 Sphingolipid signaling pathway
    127665757 (Mapk1)
   04024 cAMP signaling pathway
    127665757 (Mapk1)
   04022 cGMP-PKG signaling pathway
    127665757 (Mapk1)
   04151 PI3K-Akt signaling pathway
    127665757 (Mapk1)
   04150 mTOR signaling pathway
    127665757 (Mapk1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    127665757 (Mapk1)
   04148 Efferocytosis
    127665757 (Mapk1)
  09143 Cell growth and death
   04114 Oocyte meiosis
    127665757 (Mapk1)
   04210 Apoptosis
    127665757 (Mapk1)
   04218 Cellular senescence
    127665757 (Mapk1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    127665757 (Mapk1)
   04520 Adherens junction
    127665757 (Mapk1)
   04540 Gap junction
    127665757 (Mapk1)
   04550 Signaling pathways regulating pluripotency of stem cells
    127665757 (Mapk1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    127665757 (Mapk1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    127665757 (Mapk1)
   04613 Neutrophil extracellular trap formation
    127665757 (Mapk1)
   04620 Toll-like receptor signaling pathway
    127665757 (Mapk1)
   04621 NOD-like receptor signaling pathway
    127665757 (Mapk1)
   04625 C-type lectin receptor signaling pathway
    127665757 (Mapk1)
   04650 Natural killer cell mediated cytotoxicity
    127665757 (Mapk1)
   04660 T cell receptor signaling pathway
    127665757 (Mapk1)
   04658 Th1 and Th2 cell differentiation
    127665757 (Mapk1)
   04659 Th17 cell differentiation
    127665757 (Mapk1)
   04657 IL-17 signaling pathway
    127665757 (Mapk1)
   04662 B cell receptor signaling pathway
    127665757 (Mapk1)
   04664 Fc epsilon RI signaling pathway
    127665757 (Mapk1)
   04666 Fc gamma R-mediated phagocytosis
    127665757 (Mapk1)
   04062 Chemokine signaling pathway
    127665757 (Mapk1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    127665757 (Mapk1)
   04929 GnRH secretion
    127665757 (Mapk1)
   04912 GnRH signaling pathway
    127665757 (Mapk1)
   04915 Estrogen signaling pathway
    127665757 (Mapk1)
   04914 Progesterone-mediated oocyte maturation
    127665757 (Mapk1)
   04917 Prolactin signaling pathway
    127665757 (Mapk1)
   04921 Oxytocin signaling pathway
    127665757 (Mapk1)
   04926 Relaxin signaling pathway
    127665757 (Mapk1)
   04935 Growth hormone synthesis, secretion and action
    127665757 (Mapk1)
   04919 Thyroid hormone signaling pathway
    127665757 (Mapk1)
   04928 Parathyroid hormone synthesis, secretion and action
    127665757 (Mapk1)
   04916 Melanogenesis
    127665757 (Mapk1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    127665757 (Mapk1)
   04270 Vascular smooth muscle contraction
    127665757 (Mapk1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    127665757 (Mapk1)
  09156 Nervous system
   04724 Glutamatergic synapse
    127665757 (Mapk1)
   04725 Cholinergic synapse
    127665757 (Mapk1)
   04726 Serotonergic synapse
    127665757 (Mapk1)
   04720 Long-term potentiation
    127665757 (Mapk1)
   04730 Long-term depression
    127665757 (Mapk1)
   04723 Retrograde endocannabinoid signaling
    127665757 (Mapk1)
   04722 Neurotrophin signaling pathway
    127665757 (Mapk1)
  09158 Development and regeneration
   04360 Axon guidance
    127665757 (Mapk1)
   04380 Osteoclast differentiation
    127665757 (Mapk1)
  09159 Environmental adaptation
   04713 Circadian entrainment
    127665757 (Mapk1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    127665757 (Mapk1)
   05206 MicroRNAs in cancer
    127665757 (Mapk1)
   05205 Proteoglycans in cancer
    127665757 (Mapk1)
   05207 Chemical carcinogenesis - receptor activation
    127665757 (Mapk1)
   05208 Chemical carcinogenesis - reactive oxygen species
    127665757 (Mapk1)
   05203 Viral carcinogenesis
    127665757 (Mapk1)
   05230 Central carbon metabolism in cancer
    127665757 (Mapk1)
   05231 Choline metabolism in cancer
    127665757 (Mapk1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    127665757 (Mapk1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    127665757 (Mapk1)
   05212 Pancreatic cancer
    127665757 (Mapk1)
   05225 Hepatocellular carcinoma
    127665757 (Mapk1)
   05226 Gastric cancer
    127665757 (Mapk1)
   05214 Glioma
    127665757 (Mapk1)
   05216 Thyroid cancer
    127665757 (Mapk1)
   05221 Acute myeloid leukemia
    127665757 (Mapk1)
   05220 Chronic myeloid leukemia
    127665757 (Mapk1)
   05218 Melanoma
    127665757 (Mapk1)
   05211 Renal cell carcinoma
    127665757 (Mapk1)
   05219 Bladder cancer
    127665757 (Mapk1)
   05215 Prostate cancer
    127665757 (Mapk1)
   05213 Endometrial cancer
    127665757 (Mapk1)
   05224 Breast cancer
    127665757 (Mapk1)
   05223 Non-small cell lung cancer
    127665757 (Mapk1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    127665757 (Mapk1)
   05170 Human immunodeficiency virus 1 infection
    127665757 (Mapk1)
   05161 Hepatitis B
    127665757 (Mapk1)
   05160 Hepatitis C
    127665757 (Mapk1)
   05171 Coronavirus disease - COVID-19
    127665757 (Mapk1)
   05164 Influenza A
    127665757 (Mapk1)
   05163 Human cytomegalovirus infection
    127665757 (Mapk1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    127665757 (Mapk1)
   05165 Human papillomavirus infection
    127665757 (Mapk1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    127665757 (Mapk1)
   05135 Yersinia infection
    127665757 (Mapk1)
   05133 Pertussis
    127665757 (Mapk1)
   05152 Tuberculosis
    127665757 (Mapk1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    127665757 (Mapk1)
   05140 Leishmaniasis
    127665757 (Mapk1)
   05142 Chagas disease
    127665757 (Mapk1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    127665757 (Mapk1)
   05020 Prion disease
    127665757 (Mapk1)
   05022 Pathways of neurodegeneration - multiple diseases
    127665757 (Mapk1)
  09165 Substance dependence
   05034 Alcoholism
    127665757 (Mapk1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    127665757 (Mapk1)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    127665757 (Mapk1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    127665757 (Mapk1)
   04934 Cushing syndrome
    127665757 (Mapk1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    127665757 (Mapk1)
   01524 Platinum drug resistance
    127665757 (Mapk1)
   01522 Endocrine resistance
    127665757 (Mapk1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:asyl01001]
    127665757 (Mapk1)
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:asyl03036]
    127665757 (Mapk1)
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:asyl04147]
    127665757 (Mapk1)
Enzymes [BR:asyl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.24  mitogen-activated protein kinase
     127665757 (Mapk1)
Protein kinases [BR:asyl01001]
 Serine/threonine kinases: CMGC group
  MAPK family [OT]
   127665757 (Mapk1)
Chromosome and associated proteins [BR:asyl03036]
 Eukaryotic type
  Centromeric chromatin formation proteins
   SAC (spindle assembly checkpoint) factors
    Protein kinases
     127665757 (Mapk1)
Exosome [BR:asyl04147]
 Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   127665757 (Mapk1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr ABC1 APH Haspin_kinase STATB_N FTA2 Kdo
Other DBs
NCBI-GeneID: 127665757
NCBI-ProteinID: XP_052014239
LinkDB
Position
15:complement(84333031..84394319)
AA seq 358 aa
MAAAAAAGPEMVRGQVFDVGPRYTNLSYIGEGAYGMVCSAYDNLNKVRVAIKKISPFEHQ
TYCQRTLREIKILLRFRHENIIGINDIIRAPTIEQMKDVYIVQDLMETDLYKLLKTQHLS
NDHICYFLYQILRGLKYIHSANVLHRDLKPSNLLLNTTCDLKICDFGLARVADPDHDHTG
FLTEYVATRWYRAPEIMLNSKGYTKSIDIWSVGCILAEMLSNRPIFPGKHYLDQLNHILG
ILGSPSQEDLNCIINLKARNYLLSLPHKNKVPWNRLFPNADSKALDLLDKMLTFNPHKRI
EVEQALAHPYLEQYYDPSDEPIAEAPFKFDMELDDLPKEKLKELIFEETARFQPGYRS
NT seq 1077 nt   +upstreamnt  +downstreamnt
atggcggcggcggcggcggcgggcccggagatggtccgcgggcaggtgttcgacgtgggg
ccgcgctacaccaacctctcgtacattggagaaggcgcctacggcatggtttgctctgct
tatgataatctcaacaaagttcgagttgctatcaagaaaatcagtccttttgagcaccag
acctactgtcaaagaaccctaagagagataaaaatcttactgcgcttcagacatgagaac
atcatcggcatcaatgacatcatccgggcaccaaccattgagcaaatgaaagatgtatat
atagtacaggacctcatggagacagatctttacaagctcttgaagacacaacacctcagc
aatgaccatatctgctattttctttatcagatcctgagaggattaaaatatatccattca
gctaatgttctgcaccgtgacctcaagccttccaacctcctgctgaacaccacttgtgat
ctcaagatctgtgactttggccttgcccgtgttgcagatccagatcatgatcacacaggg
ttcttgacagagtacgtagccacgcgttggtacagagctccagaaattatgttgaattcc
aagggttataccaagtccattgatatttggtctgtgggctgcatcctggcagagatgcta
tccaacaggcctatcttcccaggaaagcattaccttgaccaactgaatcacatcctgggt
attcttggatctccatcacaggaagatctgaattgtataataaatttaaaagctagaaac
tatttgctttctcttccgcacaaaaataaggtgccatggaacaggttgttcccaaatgct
gactccaaagctctggatttactggataaaatgttgacatttaaccctcacaagaggatt
gaagttgaacaggctctggcccacccatacctggagcagtattatgacccaagtgatgag
cccattgctgaagcgccattcaagtttgacatggagttggacgacttacctaaggagaag
ctcaaagaactcatttttgaagagactgctagattccagccaggatacagatcttaa

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