KEGG   Apodemus sylvaticus (European woodmouse): 127681686
Entry
127681686         CDS       T10613                                 
Symbol
Pik3cd
Name
(RefSeq) phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform isoform X1
  KO
K00922  phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha/beta/delta [EC:2.7.1.153]
Organism
asyl  Apodemus sylvaticus (European woodmouse)
Pathway
asyl00562  Inositol phosphate metabolism
asyl01100  Metabolic pathways
asyl01521  EGFR tyrosine kinase inhibitor resistance
asyl01522  Endocrine resistance
asyl01524  Platinum drug resistance
asyl04012  ErbB signaling pathway
asyl04014  Ras signaling pathway
asyl04015  Rap1 signaling pathway
asyl04024  cAMP signaling pathway
asyl04062  Chemokine signaling pathway
asyl04066  HIF-1 signaling pathway
asyl04068  FoxO signaling pathway
asyl04070  Phosphatidylinositol signaling system
asyl04071  Sphingolipid signaling pathway
asyl04072  Phospholipase D signaling pathway
asyl04081  Hormone signaling
asyl04140  Autophagy - animal
asyl04150  mTOR signaling pathway
asyl04151  PI3K-Akt signaling pathway
asyl04152  AMPK signaling pathway
asyl04210  Apoptosis
asyl04211  Longevity regulating pathway
asyl04213  Longevity regulating pathway - multiple species
asyl04218  Cellular senescence
asyl04360  Axon guidance
asyl04370  VEGF signaling pathway
asyl04380  Osteoclast differentiation
asyl04510  Focal adhesion
asyl04550  Signaling pathways regulating pluripotency of stem cells
asyl04611  Platelet activation
asyl04613  Neutrophil extracellular trap formation
asyl04620  Toll-like receptor signaling pathway
asyl04625  C-type lectin receptor signaling pathway
asyl04630  JAK-STAT signaling pathway
asyl04650  Natural killer cell mediated cytotoxicity
asyl04660  T cell receptor signaling pathway
asyl04662  B cell receptor signaling pathway
asyl04664  Fc epsilon RI signaling pathway
asyl04666  Fc gamma R-mediated phagocytosis
asyl04668  TNF signaling pathway
asyl04670  Leukocyte transendothelial migration
asyl04722  Neurotrophin signaling pathway
asyl04725  Cholinergic synapse
asyl04750  Inflammatory mediator regulation of TRP channels
asyl04810  Regulation of actin cytoskeleton
asyl04910  Insulin signaling pathway
asyl04914  Progesterone-mediated oocyte maturation
asyl04915  Estrogen signaling pathway
asyl04917  Prolactin signaling pathway
asyl04919  Thyroid hormone signaling pathway
asyl04923  Regulation of lipolysis in adipocytes
asyl04926  Relaxin signaling pathway
asyl04929  GnRH secretion
asyl04930  Type II diabetes mellitus
asyl04931  Insulin resistance
asyl04932  Non-alcoholic fatty liver disease
asyl04933  AGE-RAGE signaling pathway in diabetic complications
asyl04935  Growth hormone synthesis, secretion and action
asyl04960  Aldosterone-regulated sodium reabsorption
asyl04973  Carbohydrate digestion and absorption
asyl05010  Alzheimer disease
asyl05017  Spinocerebellar ataxia
asyl05020  Prion disease
asyl05100  Bacterial invasion of epithelial cells
asyl05132  Salmonella infection
asyl05135  Yersinia infection
asyl05142  Chagas disease
asyl05146  Amoebiasis
asyl05160  Hepatitis C
asyl05161  Hepatitis B
asyl05162  Measles
asyl05163  Human cytomegalovirus infection
asyl05164  Influenza A
asyl05165  Human papillomavirus infection
asyl05166  Human T-cell leukemia virus 1 infection
asyl05167  Kaposi sarcoma-associated herpesvirus infection
asyl05168  Herpes simplex virus 1 infection
asyl05169  Epstein-Barr virus infection
asyl05170  Human immunodeficiency virus 1 infection
asyl05171  Coronavirus disease - COVID-19
asyl05200  Pathways in cancer
asyl05203  Viral carcinogenesis
asyl05205  Proteoglycans in cancer
asyl05206  MicroRNAs in cancer
asyl05207  Chemical carcinogenesis - receptor activation
asyl05208  Chemical carcinogenesis - reactive oxygen species
asyl05210  Colorectal cancer
asyl05211  Renal cell carcinoma
asyl05212  Pancreatic cancer
asyl05213  Endometrial cancer
asyl05214  Glioma
asyl05215  Prostate cancer
asyl05218  Melanoma
asyl05220  Chronic myeloid leukemia
asyl05221  Acute myeloid leukemia
asyl05222  Small cell lung cancer
asyl05223  Non-small cell lung cancer
asyl05224  Breast cancer
asyl05225  Hepatocellular carcinoma
asyl05226  Gastric cancer
asyl05230  Central carbon metabolism in cancer
asyl05231  Choline metabolism in cancer
asyl05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
asyl05415  Diabetic cardiomyopathy
asyl05417  Lipid and atherosclerosis
asyl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:asyl00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00562 Inositol phosphate metabolism
    127681686 (Pik3cd)
 09130 Environmental Information Processing
  09132 Signal transduction
   04012 ErbB signaling pathway
    127681686 (Pik3cd)
   04014 Ras signaling pathway
    127681686 (Pik3cd)
   04015 Rap1 signaling pathway
    127681686 (Pik3cd)
   04370 VEGF signaling pathway
    127681686 (Pik3cd)
   04630 JAK-STAT signaling pathway
    127681686 (Pik3cd)
   04668 TNF signaling pathway
    127681686 (Pik3cd)
   04066 HIF-1 signaling pathway
    127681686 (Pik3cd)
   04068 FoxO signaling pathway
    127681686 (Pik3cd)
   04070 Phosphatidylinositol signaling system
    127681686 (Pik3cd)
   04072 Phospholipase D signaling pathway
    127681686 (Pik3cd)
   04071 Sphingolipid signaling pathway
    127681686 (Pik3cd)
   04024 cAMP signaling pathway
    127681686 (Pik3cd)
   04151 PI3K-Akt signaling pathway
    127681686 (Pik3cd)
   04152 AMPK signaling pathway
    127681686 (Pik3cd)
   04150 mTOR signaling pathway
    127681686 (Pik3cd)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    127681686 (Pik3cd)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    127681686 (Pik3cd)
  09143 Cell growth and death
   04210 Apoptosis
    127681686 (Pik3cd)
   04218 Cellular senescence
    127681686 (Pik3cd)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    127681686 (Pik3cd)
   04550 Signaling pathways regulating pluripotency of stem cells
    127681686 (Pik3cd)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    127681686 (Pik3cd)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    127681686 (Pik3cd)
   04613 Neutrophil extracellular trap formation
    127681686 (Pik3cd)
   04620 Toll-like receptor signaling pathway
    127681686 (Pik3cd)
   04625 C-type lectin receptor signaling pathway
    127681686 (Pik3cd)
   04650 Natural killer cell mediated cytotoxicity
    127681686 (Pik3cd)
   04660 T cell receptor signaling pathway
    127681686 (Pik3cd)
   04662 B cell receptor signaling pathway
    127681686 (Pik3cd)
   04664 Fc epsilon RI signaling pathway
    127681686 (Pik3cd)
   04666 Fc gamma R-mediated phagocytosis
    127681686 (Pik3cd)
   04670 Leukocyte transendothelial migration
    127681686 (Pik3cd)
   04062 Chemokine signaling pathway
    127681686 (Pik3cd)
  09152 Endocrine system
   04910 Insulin signaling pathway
    127681686 (Pik3cd)
   04923 Regulation of lipolysis in adipocytes
    127681686 (Pik3cd)
   04929 GnRH secretion
    127681686 (Pik3cd)
   04915 Estrogen signaling pathway
    127681686 (Pik3cd)
   04914 Progesterone-mediated oocyte maturation
    127681686 (Pik3cd)
   04917 Prolactin signaling pathway
    127681686 (Pik3cd)
   04926 Relaxin signaling pathway
    127681686 (Pik3cd)
   04935 Growth hormone synthesis, secretion and action
    127681686 (Pik3cd)
   04919 Thyroid hormone signaling pathway
    127681686 (Pik3cd)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    127681686 (Pik3cd)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    127681686 (Pik3cd)
  09156 Nervous system
   04725 Cholinergic synapse
    127681686 (Pik3cd)
   04722 Neurotrophin signaling pathway
    127681686 (Pik3cd)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    127681686 (Pik3cd)
  09158 Development and regeneration
   04360 Axon guidance
    127681686 (Pik3cd)
   04380 Osteoclast differentiation
    127681686 (Pik3cd)
  09149 Aging
   04211 Longevity regulating pathway
    127681686 (Pik3cd)
   04213 Longevity regulating pathway - multiple species
    127681686 (Pik3cd)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    127681686 (Pik3cd)
   05206 MicroRNAs in cancer
    127681686 (Pik3cd)
   05205 Proteoglycans in cancer
    127681686 (Pik3cd)
   05207 Chemical carcinogenesis - receptor activation
    127681686 (Pik3cd)
   05208 Chemical carcinogenesis - reactive oxygen species
    127681686 (Pik3cd)
   05203 Viral carcinogenesis
    127681686 (Pik3cd)
   05230 Central carbon metabolism in cancer
    127681686 (Pik3cd)
   05231 Choline metabolism in cancer
    127681686 (Pik3cd)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    127681686 (Pik3cd)
  09162 Cancer: specific types
   05210 Colorectal cancer
    127681686 (Pik3cd)
   05212 Pancreatic cancer
    127681686 (Pik3cd)
   05225 Hepatocellular carcinoma
    127681686 (Pik3cd)
   05226 Gastric cancer
    127681686 (Pik3cd)
   05214 Glioma
    127681686 (Pik3cd)
   05221 Acute myeloid leukemia
    127681686 (Pik3cd)
   05220 Chronic myeloid leukemia
    127681686 (Pik3cd)
   05218 Melanoma
    127681686 (Pik3cd)
   05211 Renal cell carcinoma
    127681686 (Pik3cd)
   05215 Prostate cancer
    127681686 (Pik3cd)
   05213 Endometrial cancer
    127681686 (Pik3cd)
   05224 Breast cancer
    127681686 (Pik3cd)
   05222 Small cell lung cancer
    127681686 (Pik3cd)
   05223 Non-small cell lung cancer
    127681686 (Pik3cd)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    127681686 (Pik3cd)
   05170 Human immunodeficiency virus 1 infection
    127681686 (Pik3cd)
   05161 Hepatitis B
    127681686 (Pik3cd)
   05160 Hepatitis C
    127681686 (Pik3cd)
   05171 Coronavirus disease - COVID-19
    127681686 (Pik3cd)
   05164 Influenza A
    127681686 (Pik3cd)
   05162 Measles
    127681686 (Pik3cd)
   05168 Herpes simplex virus 1 infection
    127681686 (Pik3cd)
   05163 Human cytomegalovirus infection
    127681686 (Pik3cd)
   05167 Kaposi sarcoma-associated herpesvirus infection
    127681686 (Pik3cd)
   05169 Epstein-Barr virus infection
    127681686 (Pik3cd)
   05165 Human papillomavirus infection
    127681686 (Pik3cd)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    127681686 (Pik3cd)
   05135 Yersinia infection
    127681686 (Pik3cd)
   05100 Bacterial invasion of epithelial cells
    127681686 (Pik3cd)
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    127681686 (Pik3cd)
   05142 Chagas disease
    127681686 (Pik3cd)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    127681686 (Pik3cd)
   05017 Spinocerebellar ataxia
    127681686 (Pik3cd)
   05020 Prion disease
    127681686 (Pik3cd)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    127681686 (Pik3cd)
   05418 Fluid shear stress and atherosclerosis
    127681686 (Pik3cd)
   05415 Diabetic cardiomyopathy
    127681686 (Pik3cd)
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    127681686 (Pik3cd)
   04932 Non-alcoholic fatty liver disease
    127681686 (Pik3cd)
   04931 Insulin resistance
    127681686 (Pik3cd)
   04933 AGE-RAGE signaling pathway in diabetic complications
    127681686 (Pik3cd)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    127681686 (Pik3cd)
   01524 Platinum drug resistance
    127681686 (Pik3cd)
   01522 Endocrine resistance
    127681686 (Pik3cd)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:asyl04131]
    127681686 (Pik3cd)
Enzymes [BR:asyl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.153  phosphatidylinositol-4,5-bisphosphate 3-kinase
     127681686 (Pik3cd)
Membrane trafficking [BR:asyl04131]
 Endocytosis
  Rab GTPases and associated proteins
   Rab associated proteins
    127681686 (Pik3cd)
SSDB
Motif
Pfam: PI3_PI4_kinase PI3Ka PI3K_p85B PI3K_rbd PI3K_C2 HPPK
Other DBs
NCBI-GeneID: 127681686
NCBI-ProteinID: XP_052034156
LinkDB
Position
3:complement(164843520..164894720)
AA seq 1048 aa
MPPGVDCPMEFWTREESQSVDVDFLLPTGIYLNFPVSRNANLSTIKQVLWHRAQYEPLFH
MLSDPEAYVFTCVNQTAEQQELEDEQRRLCDIQPFLPVLRLVAREGDRVKKLINSQISLL
IGKGLHEFDSLRDPEVNDFRTKMRQFCEEAAAHRQQLGWVEWLQYSFPLQLEPSARGWRA
GLLRVCNRALLVNVKFEGSEDSFTFQVSTKDMPLALMACALRKKATVFRQPLVEQPEEYA
LQVNGRHEYLYGSYPLCHFQYICSCLHSGLTPHLTMVHSSSILAMRDEQSNPAPQVQKPR
AKPPPIPAKKPSSVSLWSLEQPFCIELIEGRKVNADERMKLVVQAGLFHGKEMLCKTVSS
SEVNVCSEPVWKQRLEFDISVCDLPRMARLCFALYAVVEKAKKARSTKKKSKKADCPIAW
ANLMLFDYKDQLKTGERCLYMWPSVPDEKGELLNPAGTVRGNPNTESAAALVIYLPEVAP
HPVYFPALEKILELGRHGERGRITEEEQLQLREILERRGSGELYEHEKDLVWKLRHEVQE
HFPEALARLLLVTKWNKHEDVAQLPQMLYLLCSWPELPVLSALELLDFSFPDCYVGSFAI
KSLRKLTDDELFQYLLQLVQVLKYESYLDCELTKFLLGRALANRKIGHFLFWHLRSEMHV
PSVALRFGLIMEAYCRGSTHHMKVLMKQGEALSKLKALNDFVKVSSQKTTKPQTKEMMHM
CMRQETYMEALSHLQSPLDPSTLLEELCSVEQCTFMDSKMKPLWIMYSSEEAGSAGSVGI
IFKNGDDLRQDMLTLQMIQLMDVLWKQEGLDLRMTPYGCLPTGDRTGLIEVVLHSDTIAN
IQLNKSNMAATAAFNKDALLNWLKSKNPGEALDRAIEEFTLSCAGYCVATYVLGIGDRHS
DNIMIRESGQLFHIDFGHFLGNFKTKFGINRERVPFILTYDFVHVIQQGKTNNSEKFERF
RGYCERAYTILRRHGLLFLHLFALMRAAGLPELSCSKDIQYLKDSLALGKTEEEALKHFR
VKFNEALRESWKTKVNWLAHNVSKDNRQ
NT seq 3147 nt   +upstreamnt  +downstreamnt
atgccccctggggtggactgccccatggagttctggaccagagaggagagccagagcgtg
gatgttgacttcctactgcccactggcatctacttgaacttccctgtgtcccgcaatgcc
aacctcagcaccatcaagcaggtgctgtggcaccgtgcacagtatgagcccctcttccac
atgctcagcgaccctgaggcatatgtgttcacctgtgtgaaccagacagcggagcagcag
gagttggaggatgagcagcggaggctgtgtgacatccagcccttcctgcccgtgctgcgc
ctcgtggcacgcgagggggaccgcgtgaagaagctcatcaactcccagatcagcctcctc
attggcaaaggtctccatgagttcgattccctgcgggacccggaagtaaacgacttccgc
actaaaatgcgccagttttgtgaagaggctgcggctcaccgccagcagctgggctgggtg
gaatggctgcagtatagcttccccctgcagctggagccctcggcgaggggttggcgggct
ggcttactgcgagtctgcaaccgagccctgctggtcaatgtgaagttcgagggcagtgag
gacagcttcaccttccaggtatccaccaaggacatgcccctggcactgatggcctgtgcc
ctccggaaaaaggccacagtgttccggcagcctctggtggagcagcctgaggaatacgcc
ctgcaggtgaacgggcggcatgagtacctctacggcagctacccgctctgccactttcag
tacatctgcagctgcctgcacagcgggctgacgccccacctgaccatggtccactcctcc
tccatccttgccatgcgggatgagcagagcaatcctgccccccaagtgcagaaaccacgc
gccaaacctcccccgatcccggctaagaagccctcctctgtgtccctgtggtccctggaa
cagccattctgcattgagctgattgagggccgaaaagtaaatgcggacgagcggatgaag
ctggttgtgcaggccgggctcttccatggcaaggagatgctgtgcaagaccgtgtcgagc
tcagaggtgaatgtgtgctccgagcccgtgtggaagcagcggctggagtttgacatcagt
gtctgcgacctcccgagaatggctcggctctgttttgccctctatgccgtcgtggagaag
gctaagaaggcgcgctccacaaagaagaagtctaagaaggcggactgtcccatcgcttgg
gccaacctcatgctgttcgactacaaagatcagctcaagacgggagagcgctgcctctac
atgtggccctctgtcccagatgagaaaggagagctgctgaaccccgcggggacggtacgc
ggtaaccccaacaccgagagtgccgccgccctggtcatctacctgcctgaggtggccccc
caccctgtgtactttcctgctctggagaagattctggagctggggcgtcatggggagcga
gggcggatcacggaagaggagcagctgcagctgcgggagatcctggagcggcggggatct
ggggagctgtacgaacacgagaaggacctggtgtggaaactgcgccacgaagtccaggag
catttcccagaggcgctggcccgcctgctactggtcaccaagtggaataaacacgaggac
gtggcccagctgccccagatgctctatttgctgtgctcgtggcccgagctgcccgtgctg
agcgccctggaacttctggactttagctttcctgactgctacgtgggctccttcgccatc
aagtccctacggaagctgacggatgacgagctcttccagtaccttctgcagctggtgcaa
gtgctcaagtatgagtcctacctggactgcgagctgaccaaattcttgctgggccgggcc
ctggctaaccgcaagatcggacacttcctgttttggcacctccgctctgagatgcacgtg
ccgtccgtggccctgcgatttggtctcatcatggaagcctactgcaggggcagcacccac
cacatgaaggtgctgatgaagcagggggaagcgctgagcaaacttaaggccctgaatgac
ttcgtgaaggtgagctcccagaagaccaccaagccccaaaccaaggagatgatgcatatg
tgcatgcgccaggagacttacatggaagccctgtcccacctgcagtctccactcgacccc
agcaccctgctggaggaactctgcagcgtggagcagtgcaccttcatggactccaagatg
aagccgctgtggattatgtacagcagcgaggaggcgggcagcgccggcagcgtgggcatc
atctttaagaacggggatgacctccgccaggacatgctgaccctgcagatgatccagctc
atggacgtcctatggaagcaggagggcctggacctgaggatgaccccctacggctgcctc
cccaccggcgaccgcacgggcctcatcgaggtggtcctccactcggacaccatcgccaac
atccagctgaacaagagcaacatggcagccacggccgccttcaacaaggatgctctgctc
aactggctcaagtccaagaaccctggggaggccctggatcgggcgatcgaggaattcacc
ctctcctgcgctggctactgtgtggctacatatgtgctgggcatcggggaccggcacagt
gacaacatcatgatcagagagagtgggcagctcttccacattgatttcggccactttctg
gggaacttcaagaccaagttcggaatcaaccgtgagcgcgttccctttatcctcacctac
gactttgttcacgtgatccagcaggggaagactaacaacagtgagaagtttgaaaggttc
cggggctactgtgaacgagcctacaccatcctgaggcgccacgggctgcttttcctccat
ctcttcgccctgatgcgggccgcaggtctgccagagcttagctgctccaaagacatccag
tatctcaaggattctctggcactcgggaagacagaggaagaggcgctcaagcacttccgg
gtgaagttcaacgaagctctccgggagagctggaaaaccaaagtcaactggctggcgcat
aacgtgtccaaggataacagacagtaa

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