Apodemus sylvaticus (European woodmouse): 127682069
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Entry
127682069 CDS
T10613
Symbol
Pdha2
Name
(RefSeq) pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial isoform X1
KO
K00161
pyruvate dehydrogenase E1 component subunit alpha [EC:
1.2.4.1
]
Organism
asyl Apodemus sylvaticus (European woodmouse)
Pathway
asyl00010
Glycolysis / Gluconeogenesis
asyl00020
Citrate cycle (TCA cycle)
asyl00620
Pyruvate metabolism
asyl00785
Lipoic acid metabolism
asyl01100
Metabolic pathways
asyl01200
Carbon metabolism
asyl01210
2-Oxocarboxylic acid metabolism
asyl04066
HIF-1 signaling pathway
asyl04922
Glucagon signaling pathway
asyl05230
Central carbon metabolism in cancer
asyl05415
Diabetic cardiomyopathy
Module
asyl_M00307
Pyruvate oxidation, pyruvate => acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
asyl00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00010 Glycolysis / Gluconeogenesis
127682069 (Pdha2)
00020 Citrate cycle (TCA cycle)
127682069 (Pdha2)
00620 Pyruvate metabolism
127682069 (Pdha2)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
127682069 (Pdha2)
09130 Environmental Information Processing
09132 Signal transduction
04066 HIF-1 signaling pathway
127682069 (Pdha2)
09150 Organismal Systems
09152 Endocrine system
04922 Glucagon signaling pathway
127682069 (Pdha2)
09160 Human Diseases
09161 Cancer: overview
05230 Central carbon metabolism in cancer
127682069 (Pdha2)
09166 Cardiovascular disease
05415 Diabetic cardiomyopathy
127682069 (Pdha2)
Enzymes [BR:
asyl01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.1 pyruvate dehydrogenase (acetyl-transferring)
127682069 (Pdha2)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
DXP_synthase_N
Motif
Other DBs
NCBI-GeneID:
127682069
NCBI-ProteinID:
XP_052034447
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All DBs
Position
4:21166148..21167311
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AA seq
387 aa
AA seq
DB search
MRKMLAAVFSGMVQKPALRGLLSSLKFSNDITCDIKKCDLYRLEEGPPTSTVLTRDEALK
YYRTMQVIRRMELKADQMYKQKFIRGFCHLCDGQEACCVGLEAGINPTDHIITSYRAHGL
CYTRGLSVKSILAELTGRKGGCAKGKGGSMHMYCKNFYGGNGIVGAQVPLGAGVAFACKY
LKNGQICLALYGDGAANQGQVFETYNMSALWKLPCIFICENNRYAMGTATDRAAASTDYH
KKGFVIPGLRVNGMDILSVREATKFAANHCRSGKGPILMELQTYRYHGHSMSDPGVSYRT
REEVQSVRSKSDPIMLLRERMINNNLSNVDELKEIDADVKKEVEEAAQFAATDPEPALEE
IADYLYHKNPPFEVRGAHKWLKYTSRS
NT seq
1164 nt
NT seq
+upstream
nt +downstream
nt
atgaggaaaatgctggccgctgtattttcgggaatggtccagaagccagctctcagagga
ctgctgtcatctcttaagttctccaacgacatcacctgtgacattaagaaatgcgacctg
taccggttggaagagggcccccccacctcgaccgtgctcaccagagacgaggccctcaag
tactaccggaccatgcaggtaattcggcgcatggagttgaaggccgaccagatgtataag
cagaagttcattcgaggtttctgtcacctgtgtgatgggcaggaagcctgctgcgtgggg
ctggaggcagggatcaatcccacggatcatatcatcacgtcctaccgggctcatggcttg
tgctacacgcggggactctcagtgaagtccattctcgcagagctgactggacgcaaagga
ggctgtgctaaaggcaagggaggctctatgcacatgtactgcaagaacttctacggaggc
aatggcattgttggggcacaggtacccctgggagctggcgtggctttcgcctgtaaatac
ctgaagaatggtcagatctgcttggctttgtatggtgatggcgcggctaaccaagggcag
gtgttcgaaacatacaatatgtcagccttgtggaaattgccctgtattttcatctgtgag
aataaccgctatgcgatgggaacagctactgatagagcagcagccagtactgattaccac
aagaaaggctttgttatccctggactgagggtgaatgggatggatatcctgagtgttcgt
gaggccaccaagtttgcggctaatcactgcagatctggaaaggggcccattttgatggag
ctgcagacctaccgttaccatggacacagcatgagcgatccaggagtcagttatcgtacc
cgagaagaagttcagagcgtgagaagtaagagtgatcctataatgcttctccgagagaga
atgataaacaacaacctcagcaatgttgacgaattaaaagaaattgatgcagatgtgaag
aaagaagttgaggaagcagctcagtttgctgcgactgatccagaacccgctctggaagaa
atagccgattacctctaccacaaaaatccaccttttgaagtccgtggtgcacataagtgg
ctcaagtatacgtcccgcagttag
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