Apodemus sylvaticus (European woodmouse): 127685244
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Entry
127685244 CDS
T10613
Symbol
Fpgs
Name
(RefSeq) folylpolyglutamate synthase, mitochondrial
KO
K01930
folylpolyglutamate synthase [EC:
6.3.2.17
]
Organism
asyl Apodemus sylvaticus (European woodmouse)
Pathway
asyl00790
Folate biosynthesis
asyl01100
Metabolic pathways
asyl01240
Biosynthesis of cofactors
asyl01523
Antifolate resistance
asyl04981
Folate transport and metabolism
Brite
KEGG Orthology (KO) [BR:
asyl00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00790 Folate biosynthesis
127685244 (Fpgs)
09150 Organismal Systems
09154 Digestive system
04981 Folate transport and metabolism
127685244 (Fpgs)
09160 Human Diseases
09176 Drug resistance: antineoplastic
01523 Antifolate resistance
127685244 (Fpgs)
Enzymes [BR:
asyl01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.17 tetrahydrofolate synthase
127685244 (Fpgs)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-GeneID:
127685244
NCBI-ProteinID:
XP_052038161
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Position
5:complement(11677998..11689188)
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AA seq
587 aa
AA seq
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MSWARSHLCSALSLAAVSARGATTEGAARRWLSAWPAPQEPSMEYQDAVRTLNTLQTNAS
YLEQVKRQRSDPQAQLEAMEMYLVRSGLQAEDLNRLNIIHVTGTKGKGSTCAFTERILRN
YGLKTGFFSSPHLVQVRERIRINGKPISPELFTKHFWHLYNQLEEFKDDSHGSMPSYFRF
LTLMAFHVFLQEKVDLAVVEVGIGGAFDCTNIIRKPVVCGVSSLGIDHTSLLGDTVEKIA
WQKAGIFKPGVPAFTVLQPEGPLGVLRDRAQQISCPLYLCPPLEALEEVGLPLSLGLEGE
HQRSNAALALQLAHCWLEQQNHHDIRELKVSRPSIRWQLPLAPVFRPTPHMRRGLRDTVW
PGRTQILRRGPLTWYLDGAHTTSSVQACVHWYCQSLERSRRTDGGPEVHILLFNSTGDRD
SAALLKLLQPCQFDYAVFCPNVTEVSSVGNADQQNFTVTLDQVLLRCLQHQQHWNCLAEK
QANSNLWSSCGPEPAGPGSLLLAPHPPQPTSSGSLVFSCISHALQWISQGRDPIFQPQSP
PRSLLNHPTANSGASILREAAAIHVLITGSLHLVGGALKLLEPSMSQ
NT seq
1764 nt
NT seq
+upstream
nt +downstream
nt
atgtcgtgggcgcggagccacctgtgctcggctttatccctggcagctgtttctgcgcgt
ggtgcaacgacggagggcgcggcgcggcggtggttgagcgcgtggccagcgccacaggag
ccgagcatggagtatcaggatgctgtgcggaccctcaacaccctgcaaaccaatgccagc
tacctggagcaggtaaagcgacaacggagtgaccctcaggcgcagctggaggctatggag
atgtacctggtccggagtggactgcaggcggaagacttgaaccggctaaacattatccat
gtcactgggaccaaaggaaagggctccacctgtgccttcaccgaacggatcctgcggaat
tacggcctgaagactggcttctttagctctccccacctggtgcaggtgcgtgagcggatt
cgaatcaacgggaagcccatcagccccgagctctttaccaagcacttctggcacctctat
aaccagctggaggaattcaaggatgacagccacggttccatgccctcctacttccgcttc
ctcacgctcatggccttccatgtcttcctccaggagaaggtggacctggctgtggtggag
gtgggcattggcggggcttttgactgcaccaacattatcagaaagccagtggtgtgtgga
gtctcctctcttggcattgaccacaccagtctgctaggagacacggtggagaaaatagca
tggcagaaagcgggcatctttaagcctggtgtccctgccttcaccgtgctacagccagag
ggtcccctgggcgtgctaagggatcgagctcagcagatctcatgccccctgtacctgtgt
ccgccattggaagctctggaggaggttggactgccgttgagcctgggcctggagggagag
caccagcgctctaatgcagccttagccttgcagctggcccactgttggctggagcagcag
aaccaccacgacatccgagagctgaaggtatccaggccaagcatacggtggcagctgccc
ctggcacccgtgttccgccctacgccccacatgagacgtgggcttcgggacacagtgtgg
cctggccggacacagatactccggcgaggaccccttacctggtacctggatggcgcgcat
accaccagcagtgtgcaggcctgtgtgcactggtactgccagtcattggagcgcagcaga
cgcacggatggcgggcctgaagtacacatcttgctcttcaactccaccggtgacagggac
tctgctgccctgctgaagttgctgcagccttgccagtttgactacgccgtcttctgcccc
aacgtgacagaggtctcatctgtaggaaacgcagaccagcagaacttcactgtgactctg
gaccaggtgttgctccgctgcctccaacaccagcagcattggaactgcctggccgagaaa
caggccaactccaacctctggagcagctgcggcccagaacctgcggggccaggctccctg
ctgctggcaccacacccacctcagcccacaagctccggctcccttgttttcagctgcatc
tcccacgccctgcagtggatcagccaaggccgcgatcccatcttccagccccagagccct
ccaaggagccttctcaaccaccccacagccaacagcggggccagcattctccgcgaggct
gctgccatccatgttctgattacaggaagcctgcacctggtgggtggggctctgaagctg
ctggagccctctatgtcccagtag
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