Apodemus sylvaticus (European woodmouse): 127686741
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Entry
127686741 CDS
T10613
Symbol
Srd5a2
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 2
KO
K12344
3-oxo-5-alpha-steroid 4-dehydrogenase 2 [EC:
1.3.1.22
]
Organism
asyl Apodemus sylvaticus (European woodmouse)
Pathway
asyl00140
Steroid hormone biosynthesis
asyl01100
Metabolic pathways
asyl05215
Prostate cancer
Module
asyl_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
Brite
Enzymes [BR:
asyl01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
127686741 (Srd5a2)
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NCBI-GeneID:
127686741
NCBI-ProteinID:
XP_052040746
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Position
6:116480986..116519008
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AA seq
254 aa
AA seq
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MQIVCHQVPVLAGSATLATMGTLILCLRKPANYGKHSKSVSSRVPLLPARIAWFLQELPS
FVVSVGMLAWQPRSLFGPPGNVLLGLFSAHYFHRTFIYALLTRGRPLSAVIFLRATAFCI
GNGLLQAYYLVYCAEYPEEWYTDVRFSFGVFLFILGMGINVHSDYMLRQLRKPGEVIYRI
PQGGLFTYVSGANFLGEIIEWMGYALATWSIPAFAFAFFTLCFLGKQAFYHHRFYLKMFK
DYPKSRKALIPFIF
NT seq
765 nt
NT seq
+upstream
nt +downstream
nt
atgcagattgtgtgccatcaggtcccggtgctggcgggtagcgccacattggccaccatg
gggactttgatcctgtgtcttaggaaacccgccaattatgggaaacacagcaagagtgtg
tcttcgagagttcccctcctgcccgcacgcatagcctggttcctgcaggagctgccttcc
tttgtggtgtctgtagggatgctcgcttggcagccgcgctccctcttcggaccgcccggg
aatgtgctgctgggtctcttctccgcacattacttccacaggacatttatttatgccttg
ctcaccagaggaaggcctttatcagcggtgatctttctgagagccactgccttctgcata
gggaacggactccttcaagcctactacctggtttattgcgcagaatacccggaggagtgg
tacacagacgtgcggtttagcttcggtgtcttcctgtttattttgggaatgggaatcaac
gtccacagcgactatatgctgcgccagctcaggaagccgggagaagtcatctacaggatc
ccacaaggtggtttgtttacgtatgtttctggagccaatttcctgggagagattattgaa
tggatgggctacgccttggccacttggtccattccggcttttgcttttgcatttttcaca
ctttgtttcctggggaagcaagctttttaccaccacaggttctacctcaagatgtttaag
gattaccccaaatctaggaaagcccttattccattcatcttttaa
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