KEGG   Apodemus sylvaticus (European woodmouse): 127686902
Entry
127686902         CDS       T10613                                 
Symbol
Akt1
Name
(RefSeq) RAC-alpha serine/threonine-protein kinase isoform X1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
asyl  Apodemus sylvaticus (European woodmouse)
Pathway
asyl01521  EGFR tyrosine kinase inhibitor resistance
asyl01522  Endocrine resistance
asyl01524  Platinum drug resistance
asyl04010  MAPK signaling pathway
asyl04012  ErbB signaling pathway
asyl04014  Ras signaling pathway
asyl04015  Rap1 signaling pathway
asyl04022  cGMP-PKG signaling pathway
asyl04024  cAMP signaling pathway
asyl04062  Chemokine signaling pathway
asyl04066  HIF-1 signaling pathway
asyl04068  FoxO signaling pathway
asyl04071  Sphingolipid signaling pathway
asyl04072  Phospholipase D signaling pathway
asyl04140  Autophagy - animal
asyl04150  mTOR signaling pathway
asyl04151  PI3K-Akt signaling pathway
asyl04152  AMPK signaling pathway
asyl04210  Apoptosis
asyl04211  Longevity regulating pathway
asyl04213  Longevity regulating pathway - multiple species
asyl04218  Cellular senescence
asyl04261  Adrenergic signaling in cardiomyocytes
asyl04370  VEGF signaling pathway
asyl04371  Apelin signaling pathway
asyl04380  Osteoclast differentiation
asyl04510  Focal adhesion
asyl04517  IgSF CAM signaling
asyl04518  Integrin signaling
asyl04550  Signaling pathways regulating pluripotency of stem cells
asyl04611  Platelet activation
asyl04613  Neutrophil extracellular trap formation
asyl04620  Toll-like receptor signaling pathway
asyl04625  C-type lectin receptor signaling pathway
asyl04630  JAK-STAT signaling pathway
asyl04660  T cell receptor signaling pathway
asyl04662  B cell receptor signaling pathway
asyl04664  Fc epsilon RI signaling pathway
asyl04666  Fc gamma R-mediated phagosome formation
asyl04668  TNF signaling pathway
asyl04722  Neurotrophin signaling pathway
asyl04725  Cholinergic synapse
asyl04728  Dopaminergic synapse
asyl04810  Regulation of actin cytoskeleton
asyl04910  Insulin signaling pathway
asyl04914  Progesterone-mediated oocyte maturation
asyl04915  Estrogen signaling pathway
asyl04917  Prolactin signaling pathway
asyl04919  Thyroid hormone signaling pathway
asyl04920  Adipocytokine signaling pathway
asyl04922  Glucagon signaling pathway
asyl04923  Regulation of lipolysis in adipocytes
asyl04926  Relaxin signaling pathway
asyl04929  GnRH secretion
asyl04931  Insulin resistance
asyl04932  Non-alcoholic fatty liver disease
asyl04933  AGE-RAGE signaling pathway in diabetic complications
asyl04935  Growth hormone synthesis, secretion and action
asyl04936  Alcoholic liver disease
asyl04973  Carbohydrate digestion and absorption
asyl05010  Alzheimer disease
asyl05017  Spinocerebellar ataxia
asyl05132  Salmonella infection
asyl05135  Yersinia infection
asyl05142  Chagas disease
asyl05145  Toxoplasmosis
asyl05152  Tuberculosis
asyl05160  Hepatitis C
asyl05161  Hepatitis B
asyl05162  Measles
asyl05163  Human cytomegalovirus infection
asyl05164  Influenza A
asyl05165  Human papillomavirus infection
asyl05166  Human T-cell leukemia virus 1 infection
asyl05167  Kaposi sarcoma-associated herpesvirus infection
asyl05168  Herpes simplex virus 1 infection
asyl05169  Epstein-Barr virus infection
asyl05170  Human immunodeficiency virus 1 infection
asyl05200  Pathways in cancer
asyl05205  Proteoglycans in cancer
asyl05207  Chemical carcinogenesis - receptor activation
asyl05208  Chemical carcinogenesis - reactive oxygen species
asyl05210  Colorectal cancer
asyl05211  Renal cell carcinoma
asyl05212  Pancreatic cancer
asyl05213  Endometrial cancer
asyl05214  Glioma
asyl05215  Prostate cancer
asyl05218  Melanoma
asyl05220  Chronic myeloid leukemia
asyl05221  Acute myeloid leukemia
asyl05222  Small cell lung cancer
asyl05223  Non-small cell lung cancer
asyl05224  Breast cancer
asyl05225  Hepatocellular carcinoma
asyl05226  Gastric cancer
asyl05230  Central carbon metabolism in cancer
asyl05231  Choline metabolism in cancer
asyl05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
asyl05415  Diabetic cardiomyopathy
asyl05417  Lipid and atherosclerosis
asyl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:asyl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    127686902 (Akt1)
   04012 ErbB signaling pathway
    127686902 (Akt1)
   04014 Ras signaling pathway
    127686902 (Akt1)
   04015 Rap1 signaling pathway
    127686902 (Akt1)
   04370 VEGF signaling pathway
    127686902 (Akt1)
   04371 Apelin signaling pathway
    127686902 (Akt1)
   04630 JAK-STAT signaling pathway
    127686902 (Akt1)
   04668 TNF signaling pathway
    127686902 (Akt1)
   04066 HIF-1 signaling pathway
    127686902 (Akt1)
   04068 FoxO signaling pathway
    127686902 (Akt1)
   04072 Phospholipase D signaling pathway
    127686902 (Akt1)
   04071 Sphingolipid signaling pathway
    127686902 (Akt1)
   04024 cAMP signaling pathway
    127686902 (Akt1)
   04022 cGMP-PKG signaling pathway
    127686902 (Akt1)
   04151 PI3K-Akt signaling pathway
    127686902 (Akt1)
   04152 AMPK signaling pathway
    127686902 (Akt1)
   04150 mTOR signaling pathway
    127686902 (Akt1)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    127686902 (Akt1)
   04518 Integrin signaling
    127686902 (Akt1)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    127686902 (Akt1)
  09143 Cell growth and death
   04210 Apoptosis
    127686902 (Akt1)
   04218 Cellular senescence
    127686902 (Akt1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    127686902 (Akt1)
   04550 Signaling pathways regulating pluripotency of stem cells
    127686902 (Akt1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    127686902 (Akt1)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    127686902 (Akt1)
   04613 Neutrophil extracellular trap formation
    127686902 (Akt1)
   04620 Toll-like receptor signaling pathway
    127686902 (Akt1)
   04625 C-type lectin receptor signaling pathway
    127686902 (Akt1)
   04660 T cell receptor signaling pathway
    127686902 (Akt1)
   04662 B cell receptor signaling pathway
    127686902 (Akt1)
   04664 Fc epsilon RI signaling pathway
    127686902 (Akt1)
   04666 Fc gamma R-mediated phagosome formation
    127686902 (Akt1)
   04062 Chemokine signaling pathway
    127686902 (Akt1)
  09152 Endocrine system
   04910 Insulin signaling pathway
    127686902 (Akt1)
   04922 Glucagon signaling pathway
    127686902 (Akt1)
   04923 Regulation of lipolysis in adipocytes
    127686902 (Akt1)
   04920 Adipocytokine signaling pathway
    127686902 (Akt1)
   04929 GnRH secretion
    127686902 (Akt1)
   04915 Estrogen signaling pathway
    127686902 (Akt1)
   04914 Progesterone-mediated oocyte maturation
    127686902 (Akt1)
   04917 Prolactin signaling pathway
    127686902 (Akt1)
   04926 Relaxin signaling pathway
    127686902 (Akt1)
   04935 Growth hormone synthesis, secretion and action
    127686902 (Akt1)
   04919 Thyroid hormone signaling pathway
    127686902 (Akt1)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    127686902 (Akt1)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    127686902 (Akt1)
  09156 Nervous system
   04725 Cholinergic synapse
    127686902 (Akt1)
   04728 Dopaminergic synapse
    127686902 (Akt1)
   04722 Neurotrophin signaling pathway
    127686902 (Akt1)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    127686902 (Akt1)
  09149 Aging
   04211 Longevity regulating pathway
    127686902 (Akt1)
   04213 Longevity regulating pathway - multiple species
    127686902 (Akt1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    127686902 (Akt1)
   05205 Proteoglycans in cancer
    127686902 (Akt1)
   05207 Chemical carcinogenesis - receptor activation
    127686902 (Akt1)
   05208 Chemical carcinogenesis - reactive oxygen species
    127686902 (Akt1)
   05230 Central carbon metabolism in cancer
    127686902 (Akt1)
   05231 Choline metabolism in cancer
    127686902 (Akt1)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    127686902 (Akt1)
  09162 Cancer: specific types
   05210 Colorectal cancer
    127686902 (Akt1)
   05212 Pancreatic cancer
    127686902 (Akt1)
   05225 Hepatocellular carcinoma
    127686902 (Akt1)
   05226 Gastric cancer
    127686902 (Akt1)
   05214 Glioma
    127686902 (Akt1)
   05221 Acute myeloid leukemia
    127686902 (Akt1)
   05220 Chronic myeloid leukemia
    127686902 (Akt1)
   05218 Melanoma
    127686902 (Akt1)
   05211 Renal cell carcinoma
    127686902 (Akt1)
   05215 Prostate cancer
    127686902 (Akt1)
   05213 Endometrial cancer
    127686902 (Akt1)
   05224 Breast cancer
    127686902 (Akt1)
   05222 Small cell lung cancer
    127686902 (Akt1)
   05223 Non-small cell lung cancer
    127686902 (Akt1)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    127686902 (Akt1)
   05170 Human immunodeficiency virus 1 infection
    127686902 (Akt1)
   05161 Hepatitis B
    127686902 (Akt1)
   05160 Hepatitis C
    127686902 (Akt1)
   05164 Influenza A
    127686902 (Akt1)
   05162 Measles
    127686902 (Akt1)
   05168 Herpes simplex virus 1 infection
    127686902 (Akt1)
   05163 Human cytomegalovirus infection
    127686902 (Akt1)
   05167 Kaposi sarcoma-associated herpesvirus infection
    127686902 (Akt1)
   05169 Epstein-Barr virus infection
    127686902 (Akt1)
   05165 Human papillomavirus infection
    127686902 (Akt1)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    127686902 (Akt1)
   05135 Yersinia infection
    127686902 (Akt1)
   05152 Tuberculosis
    127686902 (Akt1)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    127686902 (Akt1)
   05142 Chagas disease
    127686902 (Akt1)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    127686902 (Akt1)
   05017 Spinocerebellar ataxia
    127686902 (Akt1)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    127686902 (Akt1)
   05418 Fluid shear stress and atherosclerosis
    127686902 (Akt1)
   05415 Diabetic cardiomyopathy
    127686902 (Akt1)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    127686902 (Akt1)
   04932 Non-alcoholic fatty liver disease
    127686902 (Akt1)
   04931 Insulin resistance
    127686902 (Akt1)
   04933 AGE-RAGE signaling pathway in diabetic complications
    127686902 (Akt1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    127686902 (Akt1)
   01524 Platinum drug resistance
    127686902 (Akt1)
   01522 Endocrine resistance
    127686902 (Akt1)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:asyl01001]
    127686902 (Akt1)
Enzymes [BR:asyl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     127686902 (Akt1)
Protein kinases [BR:asyl01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   127686902 (Akt1)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 Seadorna_VP7
Other DBs
NCBI-GeneID: 127686902
NCBI-ProteinID: XP_052040885
LinkDB
Position
6:10016510..10037159
AA seq 488 aa
MNDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVEQRESPLNNFSVAHG
CSLTASECQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKR
QEEETMDFRSGSPSDNSGAEEMEVSLAKPKHRVTMNEFEYLKLLGKGTFGKVILVKEKAT
GRYYAMKILKKEVIVAKDEVAHTLTENRVLQNSRHPFLTALKYSFQTHDRLCFVMEYANG
GELFFHLSRERVFSEDRARFYGAEIVSALDYLHSEKNVVYRDLKLENLMLDKDGHIKITD
FGLCKEGIKDGATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQ
DHEKLFELILMEEIRFPRTLGPEAKSLLSGLLKKDPTQRLGGGSEDAKEIMQHRFFANIV
WQDVYEKKLNPPFKPQVTSETDTRYFDEEFTAQMITITPPDQDDSMECVDSERRPHFPQF
SYSASGTA
NT seq 1467 nt   +upstreamnt  +downstreamnt
atgaacgacgtagccattgtgaaggagggctggctgcacaaacgaggggaatatattaaa
acctggcggcctcgctacttcctcctcaagaatgatggcaccttcatcggctacaaggag
cggcctcaggatgtggagcagcgagagtccccgctcaacaacttctcagtggcacatgga
tgctccctgactgcttcagaatgccagctgatgaagacagagcggccaaggcccaacacc
ttcatcatccgctgcctgcagtggaccacggtcattgagcgcaccttccacgtggagacg
cccgaggagcgggaagagtggaccaccgccattcagactgtggctgatggactcaaaagg
caggaggaggagacaatggactttcgatcaggttcacccagtgacaactcaggggctgaa
gagatggaggtgtccctggccaagcccaagcaccgtgtgaccatgaacgagtttgagtac
ctgaaactcctgggcaagggcacctttgggaaggtgatcctggtgaaggagaaggccaca
ggccgctactatgccatgaagatcctcaagaaggaggtcatcgttgccaaggatgaggtg
gcccacacgcttacggagaaccgcgtcctgcagaactctaggcatcccttccttacggcc
ctcaagtactcattccagacgcacgaccgcctctgctttgtcatggagtatgccaacggg
ggtgagctcttcttccacctgtctcgagagcgcgtgttctcagaggaccgggcccgcttc
tatggcgcggagattgtgtctgccctggactacctgcactccgagaagaacgtggtgtac
cgggaccttaagctggagaacctcatgctggacaaggacgggcacatcaagataacggac
tttgggctgtgcaaggagggtatcaaggacggtgccacgatgaagaccttctgtggaacg
cccgagtacctggcccctgaggtgctggaggacaacgactacggccgtgcggtggactgg
tggggtctaggcgtggtcatgtacgagatgatgtgcggccgcctgcccttctacaaccag
gaccacgagaagctgttcgagctcatcctcatggaggagatccgcttcccacgcacactc
ggccctgaggccaagtccctgctctctgggctgctcaagaaggaccccacacagaggctt
ggtgggggctccgaggatgccaaggagatcatgcagcaccgattctttgccaacatcgtg
tggcaggacgtgtatgagaagaagctgaacccgcctttcaagccccaggtcacctctgag
actgacaccaggtattttgacgaggagttcacagctcagatgatcaccatcacgccgcct
gatcaagatgacagcatggagtgtgtggacagcgagcggaggccgcacttcccccagttc
tcctactcagccagtggcacggcctga

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