Apodemus sylvaticus (European woodmouse): 127689355
Help
Entry
127689355 CDS
T10613
Symbol
Tyk2
Name
(RefSeq) non-receptor tyrosine-protein kinase TYK2
KO
K11219
non-receptor tyrosine-protein kinase TYK2 [EC:
2.7.10.2
]
Organism
asyl Apodemus sylvaticus (European woodmouse)
Pathway
asyl04217
Necroptosis
asyl04380
Osteoclast differentiation
asyl04620
Toll-like receptor signaling pathway
asyl04621
NOD-like receptor signaling pathway
asyl04630
JAK-STAT signaling pathway
asyl04658
Th1 and Th2 cell differentiation
asyl04659
Th17 cell differentiation
asyl05145
Toxoplasmosis
asyl05160
Hepatitis C
asyl05161
Hepatitis B
asyl05162
Measles
asyl05164
Influenza A
asyl05165
Human papillomavirus infection
asyl05167
Kaposi sarcoma-associated herpesvirus infection
asyl05168
Herpes simplex virus 1 infection
asyl05169
Epstein-Barr virus infection
asyl05171
Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:
asyl00001
]
09130 Environmental Information Processing
09132 Signal transduction
04630 JAK-STAT signaling pathway
127689355 (Tyk2)
09140 Cellular Processes
09143 Cell growth and death
04217 Necroptosis
127689355 (Tyk2)
09150 Organismal Systems
09151 Immune system
04620 Toll-like receptor signaling pathway
127689355 (Tyk2)
04621 NOD-like receptor signaling pathway
127689355 (Tyk2)
04658 Th1 and Th2 cell differentiation
127689355 (Tyk2)
04659 Th17 cell differentiation
127689355 (Tyk2)
09158 Development and regeneration
04380 Osteoclast differentiation
127689355 (Tyk2)
09160 Human Diseases
09172 Infectious disease: viral
05161 Hepatitis B
127689355 (Tyk2)
05160 Hepatitis C
127689355 (Tyk2)
05171 Coronavirus disease - COVID-19
127689355 (Tyk2)
05164 Influenza A
127689355 (Tyk2)
05162 Measles
127689355 (Tyk2)
05168 Herpes simplex virus 1 infection
127689355 (Tyk2)
05167 Kaposi sarcoma-associated herpesvirus infection
127689355 (Tyk2)
05169 Epstein-Barr virus infection
127689355 (Tyk2)
05165 Human papillomavirus infection
127689355 (Tyk2)
09174 Infectious disease: parasitic
05145 Toxoplasmosis
127689355 (Tyk2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
asyl01001
]
127689355 (Tyk2)
Enzymes [BR:
asyl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
127689355 (Tyk2)
Protein kinases [BR:
asyl01001
]
Non-receptor tyrosine kinases
JAK family [OT]
127689355 (Tyk2)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
Jak1_Phl
FERM_F2
FERM_F1
SH2_1
Kdo
Kinase-like
ABC1
FERM_C_FAK1
Motif
Other DBs
NCBI-GeneID:
127689355
NCBI-ProteinID:
XP_052044908
LinkDB
All DBs
Position
7:111993307..112018354
Genome browser
AA seq
1191 aa
AA seq
DB search
MVTNMPLCGRRATSEDSQADGAEAQPLEPTRRLLVLLHWPGPEGGEPWVTFSQAALTAEE
ACIQVAHRVGITPPCLNLFALYDAQAKVWLPPNHILDTSQDGSPSPSLYFRMRFYFRNWH
GLNPQEPAVYRCGFPGAETSSDRAEQGVQLLDSASFEYLFEQGKHEFMNDVVSLRDLSSE
EEIHHFKNESLGMAFLHLCHLALSRGVPLEEMAREISFKNCIPRSFRQHIRQHNVLTRLR
LRRVFRRFLQAFRPSHLSRQVVMVKYLATLERLAPRFGSERIPVCHLEVLAQPERDPCLT
QNSGQSPGDPGPELTPGPPTHEVLVTGTGGIQWRPLQTQEPEGTNSRGTPHSSGSQSEKK
KAKAPEAGERLAGSPPEALWTCFCDFQDISHVVLKEQRVHIHLQDNKCLLLCLCSQAEAL
SFVALVDGYFRLTADSSHYLCHEVAPPRLVMSIQNGVHGPLMDPFVQAKLWPEDGLYLIQ
WSTSHLHRLILTVAHRNPASSNGPKGLRLRKFPILQQPGAFVLDGWGRTFDSLGALRLAL
QGCSLRAGDDCFPLQHCVLPRPREISNLVVMRGSRAHPRPLNLSQLSFHRVHQDEITQLS
HLGQGTRTNVYEGLLRVGGPAESKVDSGCAPEPGGASGQQLRVVLKVLDPSHHDIALAFY
ETASLMSQVSHMHLAFLHGVCVRGSENIIVTEFVEHGPLDVWLRRQRGRVPMTWKMAVAQ
QLASALSYLEDKNLVHGNVCGRNILLARLGLEEGTNPFIKLSDPGVGQGALSREERVERI
PWTAPECLSGGANSLGTATDMWGFGATLLEICFDGEAPLQGRGPSEKERFYTKKHQLPEP
SCPELATLTRQCLTYEPAQRPSFRTILRDLTRLQPQNLVGTSAVNSDSPASDPTVFHKRY
LKKIRDLGEGHFGKVSLYCYDPTNDGTGEMVAVKALKEGCGPQLRSGWQREIEILRTLYH
EHIVKYRGCCEDQGEKSVQLVMEYVPLGSLRDYLPRHSVGLAQLLLFAQQICEGMAYLHA
QHYIHRDLAARNVLLDNDRLVKIGDFGLAKAVPEGHEYYRVREDGDSPVFWYAPECLKEC
KFYYASDVWSFGVTLYELLTYCDSSQSPPTKFIEFIGLTQGQMTVLRLTEFLERGERLPR
PDRCPCEIYHLMKNCWETEASFRPTFQNLVPILKSAQEKHQGQVPSVFSVC
NT seq
3576 nt
NT seq
+upstream
nt +downstream
nt
atggtgacaaacatgcctctgtgtgggcggagagccacctcggaagacagccaagcagat
ggcgcagaagctcaacccctggagcccaccagacgcttgctggtgctgctgcactggccc
gggcctgagggcggagagccctgggtcaccttcagccaggcagctctgaccgcagaggag
gcctgcatccaagtagcccacagagtcggcatcactcccccctgcttgaatctcttcgcc
ctctacgatgctcaggccaaggtctggctgcccccaaaccacattctggacacatcccaa
gacgggagcccgagcccgagcctctattttcgaatgaggttttacttcaggaactggcac
ggcctgaatccccaggagccagctgtataccgatgtggcttcccaggggcggagacttcc
tcagaccgggccgagcagggtgtccagctgttggactctgcctcctttgaatacctgttt
gagcagggaaagcatgagttcatgaacgatgtggtgtctctgcgggacctgtccagcgag
gaggagatccaccactttaagaacgagagcttgggcatggccttcctgcacctctgccac
ctggctctcagcagaggagtccccctggaggagatggccagagagatcagcttcaagaac
tgcatccctcgttccttccgtcagcacatccgccagcacaacgtgctcacgcgcctgcgg
ctccgccgagtcttccgccgcttcctgcaggccttccggcccagccacctctcccggcag
gtggtgatggtgaagtacttggccaccctggagcggctggcccctcgctttggctcggag
cgcatacctgtgtgtcacctggaggtcctggctcagcccgagagggacccctgcctcacc
cagaacagtgggcagagccctggggacccaggcccagagctgactcccgggcctcccacc
cacgaggtactggtgacaggcaccggcggtatccagtggcgcccactacagacccaggaa
ccggaggggacaaacagcagagggactccccacagcagtggcagccagtctgagaagaag
aaagccaaggcccctgaggccggggagcgcctggcggggagtcctccggaagcgctgtgg
acctgcttctgtgacttccaggacatttcccacgtggtgctaaaggagcagcgtgtacac
atccacctgcaagacaacaagtgcttgctgctgtgcctctgttcccaggctgaggccctg
tcctttgtggcgctggtcgatggctacttccgcttgactgctgactccagccactacctg
tgccatgaggtggcacccccgaggctggtgatgagcatccagaacggtgtccacgggccc
ctgatggatccatttgttcaggccaaactgtggccagaggatggcctctacctgattcag
tggagtaccagccacctgcaccgcctgatccttacggtggcccatcgaaacccggcttcc
agtaatggccctaagggcctgcgcctgcgcaagttccccatcctccagcagcccggagcc
ttcgtgctggatggctggggccgcaccttcgacagcttgggggcccttcggctcgccttg
cagggctgctcgttgcgggcaggtgatgactgttttcccttgcaacactgcgtcctgccc
cggccaagagaaatctccaacctcgtcgtcatgcggggctctagggcccacccccggccg
ctcaacctcagtcagctgagcttccacagggtccaccaggatgaaatcacccagctgtcc
cacttgggccaaggcacgaggaccaatgtatacgagggcctgctgagagtgggaggcccc
gctgagagcaaagtggacagcggatgtgcccctgagcctggcggggccagcgggcagcag
cttcgcgtggtgctcaaggttctcgaccccagtcaccatgatatcgccttggccttctat
gaaaccgctagcctcatgagccaggtgtcacacatgcacctggctttcctgcatggcgtt
tgcgtgcgtggctcagagaatatcattgtgacagaatttgtagagcacggtcccctggat
gtgtggttacggcgacagaggggccgagtgcccatgacctggaagatggccgtggctcag
cagctggccagcgccctcagctacctggaggacaagaatctggttcatgggaacgtgtgt
ggccggaacatcctgctggcccgcctggggctggaggagggcaccaaccccttcatcaag
ctaagcgatcctggtgtgggccaaggcgccctctccagggaagagcgggtggagcgcatc
ccctggacagctcccgagtgcctgtctggaggggccaacagcttgggcactgccacggac
atgtggggcttcggggccacccttctggagatctgctttgacggggaggcgcccctgcag
ggtcgcggtccctccgagaaagaacggttttacacaaagaaacatcaactccctgagccc
tcatgcccagagctggccacactcacccgccagtgcctgacctatgaaccagcacagcgg
ccgtcattccgcaccattttgcgggatctcacaagactgcagccacagaatctagtgggc
acttcggctgtgaactcagactccccagcatcagaccccactgtcttccacaaacgttat
ttgaaaaagatccgggatttgggcgagggtcattttggcaaggtcagcctgtactgctac
gacccaaccaacgacggcactggtgagatggtggctgttaaagctctgaaggaggggtgt
ggcccccagctccgctcaggctggcagcgggagatcgagatcctgcggacgctgtaccac
gaacacatcgtcaagtacagaggctgctgcgaggaccaaggagagaagtctgtacagctg
gtcatggaatatgtccccctgggcagcctccgagactacctgccgaggcacagcgtaggg
ctggcgcagctcctgctgttcgcccagcagatctgcgagggcatggcctacctgcacgct
cagcactacattcaccgagacctcgctgcacgcaacgtactgctggacaacgacaggctg
gtcaagattggagactttggcctagccaaggctgtgcctgaaggccacgagtactaccga
gtgcgcgaggacggggacagcccagtgttctggtatgctccagaatgcctgaaggagtgc
aaattttactatgcatctgatgtctggtcctttggggtgaccctgtatgagctgttgaca
tactgtgactctagccagagtcctcccacaaaattcatcgagttcatcggcctaacccag
ggccagatgaccgtgctgaggctcacagagtttctggaacgaggagagaggctgcctcgg
cctgacagatgtccctgtgagatctatcacctcatgaagaactgctgggagacagaggcc
tccttccggcccacattccagaatcttgtgcccattctcaagtccgcgcaggagaagcac
caaggccaggtgccttcggtgttcagcgtgtgctga
DBGET
integrated database retrieval system
