Apodemus sylvaticus (European woodmouse): 127690879
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Entry
127690879 CDS
T10613
Symbol
Top2b
Name
(RefSeq) DNA topoisomerase 2-beta
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
asyl Apodemus sylvaticus (European woodmouse)
Pathway
asyl01524
Platinum drug resistance
Brite
KEGG Orthology (KO) [BR:
asyl00001
]
09160 Human Diseases
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
127690879 (Top2b)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
03032 DNA replication proteins [BR:
asyl03032
]
127690879 (Top2b)
03036 Chromosome and associated proteins [BR:
asyl03036
]
127690879 (Top2b)
Enzymes [BR:
asyl01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
127690879 (Top2b)
DNA replication proteins [BR:
asyl03032
]
Eukaryotic type
DNA Topoisomerases
127690879 (Top2b)
Chromosome and associated proteins [BR:
asyl03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
127690879 (Top2b)
Centrosome formation proteins
Centriole proteins
127690879 (Top2b)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
DNA_topoisoIV
TOPRIM_C
DNA_gyraseB
DTHCT
Toprim
HATPase_c
DUF7180
Motif
Other DBs
NCBI-GeneID:
127690879
NCBI-ProteinID:
XP_052046332
LinkDB
All DBs
Position
8:115034164..115099696
Genome browser
AA seq
1611 aa
AA seq
DB search
MAKSGLAGADGALTWVNNAAKKEDLETANKNDSSKKLSVERVYQKKTQLEHILLRPDTYI
GSVEPLTQLMWVYDEDVGMNCREVTFVPGLYKIFDEILVNAADNKQRDKNMTCIKVSIDP
ESNIISIWNNGKGIPVVEHKVEKVYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCN
IFSTKFTVETACKEYKHSFKQTWMNNMMKTSEAKIKHFDGEDYTCITFQPDLSKFKMEKL
DKDIVALMTRRAYDLAGSCKGVKVMFNGKKLPVNGFRSYVDLYVKDKLDETGVALKVIHE
LANERWDVCLTLSEKGFQQISFVNSIATTKGGRHVDYVVDQVVGKLIEVVKKKNKAGVSV
KPFQVKNHIWVFINCLIENPTFDSQTKENMTLQPKSFGSKCQLSEKFFKAASNCGIVESI
LNWVKFKAQTQLNKKCSSVKYSKIKGIPKLDDANDAGGKHSLECTLILTEGDSAKSLAVS
GLGVIGRDRYGVFPLRGKILNVREASHKQIMENAEINNIIKIVGLQYKKSYDDAESLKTL
RYGKIMIMTDQDQDGSHIKGLLINFIHHNWPSLLKHGFLEEFITPIVKASKNKQELSFYS
IPEFDEWKKHIENQKAWKIKYYKGLGTSTAKEAKEYFADMERHRILFRYAGPEDDAAITL
AFSKKKIDDRKEWLTNFMEDRRQRRLHGLPEQFLYGTATKHLTYNDFINKELILFSNSDN
ERSIPSLVDGFKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSAYHHGEQALMMTIVNL
AQNFVGSNNINLLQPIGQFGTRLHGGKDAASPRYIFTMLSSLARLLFPAVDDNLLKFLYD
DNQRVEPEWYIPIIPMVLINGAEGIGTGWACKLPNYDAREIVNNVRRMLEGLDPHPMLPN
YKNFKGTIQELGQNQYAVSGEIFVVDRNTVEITELPVRTWTQVYKEQVLEPMLNGTDKTP
ALISDYKEYHTDTTVKFVVKMTEEKLAQAEAAGLHKVFKLQTTLTCNSMVLFDHMGCLKK
YETVQDILKEFFDLRLSYYGLRKEWLVGMLGAESTKLNNQARFILEKIQGKITIENRSKK
DLIQMLVQRGYESDPVKAWKEAQEKAAEEEDTQNQHDDSSSDSGTPSGPDFNYILNMSLW
SLTKEKVEELIKQRDTKGREVNDLKRKSPSDLWKEDLAAFVEELDKVEAQEREDILAGMS
GKAIKGKVGKPKVKKLQLEETMPSPYGRRIVPEITAMKADASRKLLKKKKGDPDTTVVKV
EFDEEFSGTPVEGTGEETLTPAPVNKGPKPKREKKEPGTRVRKTPTSTGKPNAKKVKKRN
PWSDDESKSESDLEEAEPVVIPRDSLLRRAAAERPKYTFDFSEEEDDDADDDDDNNDLEE
LKVKASPITNDGEDEFVPSDSLDKDEYAFSPGKSKATPEKSSHDKKSQDFGNLFSFPSYS
QKSEDDSAKFDSNEEDTASVFAPSFGLKQTDKVPSKTAAAKKGKPPSDTAPKAKRAPKQK
KVVETINSDSDSEFGIPKKSTTPKGKGRGAKKRKASGSENEGDYNPGRRPSKTASKKPKK
TSFDQDSDVDIFPSDVTSEPPALPRTGRARKEVKYFAESDEEEDVDFAMFN
NT seq
4836 nt
NT seq
+upstream
nt +downstream
nt
atggccaagtccggcctcgcgggcgctgacggggcgctgacctgggtgaacaatgctgca
aaaaaggaagatttggaaacagcaaacaaaaatgactcttctaagaagttgtctgttgag
agagtgtaccagaagaagacccaactggagcatattctccttcgtcctgatacatacatt
ggatcagtagaaccattaacacagttaatgtgggtgtatgatgaagatgtggggatgaac
tgcagagaggtgacctttgtgccaggcttatacaagatctttgatgaaattttagttaat
gctgctgacaacaagcagagggacaagaacatgacctgtattaaggtttctattgatcct
gaatctaatattataagcatttggaataatggaaaaggcattccagtagtagaacacaaa
gtagagaaagtttatgttcctgctttaatttttggacagcttttaacatcaagtaattat
gatgatgatgagaaaaaagtgacaggaggccgtaatggttatggtgcaaaactttgtaat
atttttagtacaaagtttacagtagaaacggcttgcaaggaatacaagcatagttttaag
cagacatggatgaataatatgatgaagacttctgaagccaaaattaaacattttgatggt
gaagattatacatgcataacattccagccagatctatccaagtttaagatggaaaaactt
gacaaagacattgtggctctcatgaccagaagagcatatgatctagctggctcatgtaaa
ggggtcaaggtcatgtttaatgggaagaagttgcctgtaaatggatttcgcagctatgta
gacctgtatgtgaaagacaaattggatgaaactggggtagctctcaaagttattcatgaa
cttgcaaatgaaagatgggatgtttgtctaaccttgagtgaaaaaggtttccaacagatc
agctttgtgaatagtattgcaactacaaaaggtggacggcatgtggattatgtagtagat
caagttgttggtaaactgattgaagtagttaagaagaagaacaaagctggtgtatcagtg
aaaccatttcaagttaaaaaccatatatgggtttttattaattgtcttattgaaaatcca
acctttgattctcaaactaaggaaaacatgactctgcagcccaaaagttttgggtccaaa
tgccaactgtcagaaaaattttttaaagcagcctctaattgtggcattgtagaaagcata
ttgaactgggtgaaatttaaggctcagactcagcttaataagaaatgttcatcagtaaag
tacagtaaaatcaaaggcattcccaaactggatgatgccaacgatgctggtggcaaacac
tccctggagtgcacattaatattaacagagggtgactctgccaaatcgctcgctgtgtct
ggattaggtgtgattgggagggacagatatggagtctttccactcaggggtaaaattctc
aatgtacgagaagcatctcataaacagattatggaaaatgcagaaataaacaatattatt
aaaatagttggtttgcaatacaagaaaagttatgatgatgcagaatctctgaaaacttta
cgttatggaaagattatgattatgactgatcaggatcaagatggttctcacatcaaaggc
ctactaatcaattttattcatcataattggccatcacttttgaagcatggttttcttgaa
gagttcattactcccattgtaaaggcaagcaaaaataagcaggaactttccttttatagt
attcctgaatttgatgagtggaaaaaacatatagaaaaccagaaagcctggaaaataaag
tactacaaagggttgggtaccagtacagctaaagaagcaaaggaatattttgctgatatg
gaaaggcatcgcattttgtttagatatgctggacctgaagatgatgctgccattaccttg
gcatttagtaagaagaagattgatgacagaaaagaatggttaaccaactttatggaggat
cggagacagcgtaggttacatggcctaccagagcaatttttatatggtacagcaacaaag
catttgacatacaatgatttcatcaacaaggaattgattctcttctcaaactcagacaat
gagaggtctataccatctcttgtggacggcttcaagccaggtcaacggaaagttttgttt
acttgtttcaagaggaatgataaacgtgaagttaaagtcgcacagctggctggttctgtt
gcagaaatgtctgcttatcatcatggagaacaagcattgatgatgactattgtgaatttg
gctcagaattttgtgggcagtaacaacattaacttgcttcagcccattggtcagtttggt
actcggcttcatggtggcaaagatgctgcaagccctcgttatattttcacaatgttaagc
tctctggcaagacttctttttccagctgtggatgataacttgcttaagttcctttatgat
gataatcaacgtgtagagccggagtggtatatccctataatccccatggttttgattaat
ggtgctgagggtattgggacaggatgggcttgtaaactgcccaactatgatgctagagaa
attgtgaacaatgtcaggcggatgctagaaggtttggatcctcatcccatgcttccaaac
tataagaacttcaaaggcaccatccaggaacttggtcagaaccagtatgctgttagtggt
gagatatttgtggtggacagaaacacagtagagattacagaacttccagttagaacttgg
acacaggtatacaaggagcaggtcctagaacctatgcttaatggaacagataaaacacca
gcactgatttctgattacaaagaatatcatactgacacaactgtgaagtttgtggtgaaa
atgacagaagagaaacttgcacaagcagaagctgctggcctgcataaagtttttaagctt
caaactactcttacttgcaattccatggtactctttgatcatatgggatgtctgaagaag
tatgaaactgtgcaagacattttgaaagaattctttgatttacgattaagttattatggt
ttacggaaggaatggcttgtaggaatgctgggagcagaatctacaaagcttaataatcaa
gctcgtttcattttagagaagatacaagggaaaattactatagagaataggtcaaagaaa
gatttgattcaaatgttagtccagagaggttatgaatctgacccagtgaaagcgtggaaa
gaagcacaagaaaaggccgcagaagaggaagatacacaaaaccaacatgatgacagttcc
tctgattcaggaactccttcaggccctgattttaattatattttaaatatgtctctatgg
tctcttactaaagaaaaagttgaagaactcattaaacagagagatacaaaagggcgagag
gttaatgatctcaaaaggaaatctccttcagatctttggaaagaagacttagcagcattt
gttgaagaattggataaagtggaagcacaagaacgagaagatattctggcaggaatgtct
gggaaagcaataaaaggtaaagttggcaaacctaaagtaaagaaacttcagctggaggag
acgatgccctcaccttacgggagaagaattgttcctgaaattactgctatgaaggcagat
gccagcagaaagttgctgaagaagaagaagggtgatcctgatactacagtagtgaaagta
gaatttgatgaagaatttagtggaacaccagtagaaggtacaggagaagagacattgacc
cctgctcctgtaaataaaggccccaaacccaaaagagagaaaaaggagcctggtaccagg
gttagaaaaacacctacatcaactggtaaacctaatgcgaagaaagtgaagaaacggaat
ccttggtcagatgatgagtccaaatcagagagtgacttggaagaagcagaacctgtggtt
atcccaagagattctttgcttaggagagcagctgctgaaagacctaagtacacttttgat
ttctcagaagaggaggatgatgatgctgatgatgatgatgacaataatgatttagaagaa
ctgaaagttaaagcatctcccataacaaatgatggggaagatgaatttgttccttcagat
agcttagataaagatgagtatgccttttctccaggcaaatccaaagctactccagaaaaa
tcttcacatgacaaaaaaagtcaagattttggaaatcttttttcatttccttcatattct
cagaagtcagaggatgattcagctaaatttgacagtaatgaagaagatactgcttctgtt
tttgcaccatcatttggtctgaagcaaacagataaagttccaagtaaaacagccgctgca
aaaaagggtaaaccaccttcagatacagcccctaaagccaagagagcccctaaacagaag
aaggtagtagaaactataaactctgactcagattctgaatttggcattccaaagaagtct
acaacaccaaaaggtaaaggccgaggggcaaagaaaaggaaagcatcaggctcagaaaat
gaaggtgattataaccctggaaggagaccatctaaaacagccagcaagaaaccgaagaaa
acgtcttttgatcaggattcagatgtagacatcttcccctcagacgtcacttctgagcca
cctgctctcccaaggactggccgggctaggaaagaagtaaaatattttgcagagtctgat
gaagaagaagatgttgattttgcaatgtttaattaa
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