Apodemus sylvaticus (European woodmouse): 127693791
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Entry
127693791 CDS
T10613
Symbol
Top2a
Name
(RefSeq) DNA topoisomerase 2-alpha isoform X1
KO
K03164
DNA topoisomerase II [EC:
5.6.2.2
]
Organism
asyl Apodemus sylvaticus (European woodmouse)
Pathway
asyl01524
Platinum drug resistance
Brite
Enzymes [BR:
asyl01000
]
5. Isomerases
5.6 Isomerases altering macromolecular conformation
5.6.2 Enzymes altering nucleic acid conformation
5.6.2.2 DNA topoisomerase (ATP-hydrolysing)
127693791 (Top2a)
DNA replication proteins [BR:
asyl03032
]
Eukaryotic type
DNA Topoisomerases
127693791 (Top2a)
Chromosome and associated proteins [BR:
asyl03036
]
Eukaryotic type
Chromosome condensation proteins
Other regulators of chromosome condensation
127693791 (Top2a)
Centrosome formation proteins
Centriole proteins
127693791 (Top2a)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Other DBs
NCBI-GeneID:
127693791
NCBI-ProteinID:
XP_052050888
LinkDB
All DBs
Position
10:24049264..24079941
Genome browser
AA seq
1527 aa
AA seq
DB search
MESSPLQPVNENMLLNKKKNEDGKKRLSIERIYQKKTQLEHILLRPDTYIGSVELVTQQM
WVYDEDVGMNYREVTFVPGLYKIFDEILVNAADNKQRDPKMSCIRVTIDPENNLISIWNN
GKGIPVVEHKVEKTYVPALIFGQLLTSSNYDDDEKKVTGGRNGYGAKLCNIFSTKFTVET
ASREYKKMFKQTWMDNMGRAGDMELKPFSGEDYTCITFQPDLSKFKMQSLDKDIVALMVR
RAYDIAGSTKDVKVFLNGNRLPIKGFRSYVDMYLKDKVDETGNSLKVVHEQVNPRWEVCL
TMSEKGFQQISFVNSIATSKGGRHVDYVADQIVSKLVDVVKKKNKGGVAVKAHQVKNHMW
IFVNSLIENPTFDSQTKENMTLQAKSFGSTCQLSEKFIKAAIGCGIVESILNWVKFKAQI
QLNKKCSAVKHNKIKGIPKLDDANDAGSRNSAECTLILTEGDSAKTLAVSGLGVVGRDKY
GVFPLRGKMLNVREASHKQIMENAEINNIIKIVGLQYKKNYEDEDSLKTLRYGKIMIMTD
QDQDGSHIKGLLINFIHHNWPSLLRHRFLEEFITPIVKVSKNKQEIAFYSLPEFEEWKSS
TPNHKKWKVKYYKGLGTSTSKEAKEYFADMKRHRIQFKYSGPEDDAAISLAFSKKQVDDR
KEWLTNFMEDRRQRKLLGLPDDYLYGQTTTYLTYNDFINKELILFSNSDNERSIPSMVDG
LKPGQRKVLFTCFKRNDKREVKVAQLAGSVAEMSSYHHGEMSLMMTIINLAQNFVGSNNL
NLLQPIGQFGTRLHGGKDSASPRYIFTMLSPLARLLFPPKDDHTLRFLYDDNQRVEPEWY
IPIIPMVLINGAEGIGTGWSCKIPNFDVREVVNNIRRLLDGEEPLPMLPSYKNFKGTIEE
LVSNQYVINGEVAILDSTTIEISELPIRTWTQTYKEQVLEAMLNGTEKTPPLITDYREYH
TDTTVKFVIKMTEEKLAEAERVGLHKVFKLQTSLTCNSMVLFDHVGCLKKYDTVLDILRD
FFELRLKYYGLRKEWLLGMLTAESSKLNNQARFILEKIDGKIVIENKPKKELIKVLIQRG
YDSDPVKAWKEAQQKVPDEEENEESETETSTSDSAAESGPTFNYLLDMPLWYLTKEKKDE
LCRQRDEKEQELNTLKKKSPSDLWKEDLAVFIEELEVVEAKEKQDEQVGLPGKGGKAKGK
KAQMSEVLPSPRGKRVIPQVTVEMKAEAEKKIRKKIKSENAEGSPAEDGAEQGSLRQRLE
KKQKREPGTRAKKQTTLPFKPTKKGKKKNPWSDSESDMSSNESNFDIPPREKEPRNAAAK
AKFTVDLDSDEDFSDLDEKDEDEDFLPLDTTPPKTKVPPKNTKKAPKPQKSPTSVVDLES
DIKDSRPASPGIPAADSPAETEHLKPTSKKTVGVKKTTTKSQSLISTAITKKKAAPKATK
SDSALSISEKPAPAKAKNSRKRKPSSSDSSDSDFEKAVSKGATIKKPKGEEQDFHMDLEN
SVAPRAKSGRARKPITYLEESDEDDLF
NT seq
4584 nt
NT seq
+upstream
nt +downstream
nt
atggagtcgtctccgctgcagcctgtaaatgaaaatatgctactgaacaaaaagaagaat
gaagatggcaagaaaagattgtctattgaaagaatctatcagaaaaaaacacaactggaa
catatactgctccgcccagatacctatatcggctctgtggagctagtgacccagcaaatg
tgggtttacgatgaagacgttggcatgaactacagggaagtcacttttgttcctggtttg
tataaaatctttgatgagattctagttaatgctgctgataacaaacaaagggacccaaaa
atgtcttgtattagagtcacaattgatccagaaaataatttaattagtatctggaataat
ggaaaaggaattcctgttgttgaacacaaagttgaaaaaacatatgtcccagctctcata
tttggacagctcctgacctccagtaactatgatgacgatgagaagaaagtgacaggtggt
cgaaatggctatggagctaaactgtgtaacatattcagcaccaaatttactgtggaaaca
gccagtagagaatataagaaaatgttcaaacagacatggatggataacatggggagagct
ggtgacatggaactcaagcccttcagtggagaagattatacatgcattaccttccagcct
gacttatcgaagtttaaaatgcaaagcctagacaaagatattgttgcactgatggtcaga
agagcatatgatattgctggttccactaaagatgtcaaagtttttcttaatggaaatagg
ctgccaataaaagggttccgtagttatgtggatatgtatttgaaggataaggtagatgaa
actgggaactcactgaaggtggtacatgaacaagtaaatccccgatgggaagtgtgctta
acaatgagcgagaagggctttcagcagatcagcttcgtcaatagcattgctacttctaag
ggtggcagacatgttgattacgtagctgatcagattgtgagtaaactcgttgatgtggtg
aaaaagaagaacaagggtggcgttgcagtgaaggctcatcaggtgaaaaatcacatgtgg
atttttgtaaattccttaatcgaaaacccaacctttgattctcaaacaaaagaaaacatg
actttacaagccaagagctttggatcaacatgtcaattaagtgaaaaattcatcaaagct
gcaattggttgtggtattgtcgaaagcatactaaactgggtgaagtttaaggctcaaatc
caattaaacaagaagtgttcagctgtaaaacataacaaaatcaagggaatccccaaactg
gatgatgccaatgatgcagggagccgaaattctgctgaatgcacacttatcctgactgag
ggagactcagccaaaactctggcagtttcaggccttggagtggttggaagagacaaatat
ggggtgttccctcttagaggaaaaatgctcaatgtgcgagaagcttctcataaacagatc
atggaaaatgctgaaattaacaatatcatcaagattgtcggtcttcagtacaagaaaaac
tatgaagatgaagattcattgaaaactcttcgttatgggaagatcatgattatgacagat
caggaccaagatggttcccatatcaaaggcttgctgatcaattttatccatcacaattgg
ccgtctcttctgcgacatcgttttctagaagaatttattactcccattgtaaaggtgtcc
aaaaataagcaagaaattgcattctatagtcttcccgagtttgaagaatggaagagttcg
actccaaatcataaaaaatggaaagtcaaatactacaaaggtttgggtaccagcacatca
aaggaagctaaggaatattttgcagatatgaaacgacatcgtattcagtttaaatattcc
ggccctgaagatgatgctgccatcagcctggcctttagtaaaaaacaagttgatgatcga
aaggaatggttaactaatttcatggaagacagaagacagcggaagttacttggccttcct
gacgattatttgtatggacaaaccactacttacctgacttataatgacttcataaacaag
gaacttatcctcttctcaaactctgataatgaaagatctatcccatctatggtagatggt
ttgaaaccaggtcagagaaaggttttgtttacttgtttcaagcggaatgacaagcgagaa
gtgaaggttgcccagttagctgggtcagtggcagagatgtcctcttatcaccatggcgag
atgtcactaatgatgaccattataaatttggctcagaattttgtgggtagcaataatttg
aaccttttacagcccattggtcagtttggtaccaggctgcatggtggcaaggactcggct
agtcctaggtacatctttacaatgctcagccctttggctcggttattgtttccaccaaaa
gatgatcacacattacgatttctgtatgatgacaaccagcgtgttgagcctgaatggtat
attcctattatacccatggtactgataaatggtgctgagggaattggtacagggtggtcc
tgcaaaatccccaacttcgatgttcgtgaagttgtaaataatatcagacggctattagat
ggagaagagcctctgcccatgctcccaagttataagaatttcaaaggtactattgaagaa
ctggtttcaaatcagtatgtgattaatggagaagtagctattctggattctacaaccatt
gaaatctcagagcttcccatcagaacatggactcagacatataaagaacaggttctagaa
gccatgttgaatggcactgagaagacaccccctctaataacagattatagggaataccat
acagataccactgtgaagtttgtcataaagatgactgaagaaaaattggcagaggcagag
agagtcggactacacaaagtcttcaaactccagactagtctcacttgcaactctatggta
ctttttgaccatgtaggttgcttaaagaaatatgacactgtgctggatatcctaagagac
ttctttgagctcaggcttaaatattatggattaagaaaagaatggcttctaggaatgctt
actgcagaatcttctaagctgaataatcaagctcgctttatattagagaaaatagatggc
aaaattgtcattgaaaataaacctaaaaaagaattaattaaagttctgattcagagagga
tatgattctgaccctgtgaaagcctggaaagaagctcagcaaaaggttccagatgaagaa
gaaaacgaagaaagtgagactgaaaccagcaccagtgactctgcagcagagtctggccca
actttcaactaccttctcgacatgcccctgtggtatctaaccaaggagaagaaggatgaa
ctgtgtagacaaagagatgagaaggaacaagagctcaacacattaaagaagaagagtcca
tcagatttgtggaaggaagatctggctgtttttattgaagaactggaggttgttgaagcc
aaggaaaagcaggatgagcaagtaggacttcctgggaaggggggtaaagcaaaggggaag
aaagcgcaaatgtctgaagtcctgccttcccctcggggaaaaagagtcattccccaagtg
acggtggagatgaaagcagaggcagagaagaaaattaggaagaaaattaagagtgaaaac
gctgagggttcgcctgctgaggatggtgcagaacaaggaagcctacgacaacgattagaa
aagaagcagaagagagagccaggtaccagggcaaagaagcaaactacattgccatttaag
cctaccaaaaaagggaaaaagaaaaacccctggtctgattctgagtcagatatgagtagt
aacgaaagtaattttgatatccctccacgagaaaaagagccaagaaatgctgcagcaaag
gccaaattcacagtggatttagactccgacgaagatttctcagatttggatgaaaaggat
gaggatgaagatttcctcccattggataccactccacccaagaccaaagtccccccaaaa
aatactaaaaaagcaccgaagccacagaaaagccccacatcagtagttgatcttgaaagt
gatattaaggacagtaggccagcttctccaggcattcctgctgctgactccccagctgag
actgaacacttaaagccgacctccaaaaagactgtgggagtgaagaagacaacaaccaaa
agccagtctttaatctccactgcgattaccaaaaagaaagctgcaccaaaggcaacaaaa
tcagattcagccttgagcatctctgaaaagcctgctcctgccaaagccaagaacagtcgc
aaaaggaagccatcttcttcagatagctctgactctgattttgagaaagcagtttctaaa
ggtgccacaatcaagaaacccaagggagaggaacaggatttccatatggacttagaaaac
tctgtggctcctcgagctaaatctggacgagcaagaaagccaattacgtacctggaggag
tcggacgaagatgacctcttctga
DBGET
integrated database retrieval system
