KEGG   Apodemus sylvaticus (European woodmouse): 127694765
Entry
127694765         CDS       T10613                                 
Symbol
Map2k6
Name
(RefSeq) dual specificity mitogen-activated protein kinase kinase 6
  KO
K04433  mitogen-activated protein kinase kinase 6 [EC:2.7.12.2]
Organism
asyl  Apodemus sylvaticus (European woodmouse)
Pathway
asyl04010  MAPK signaling pathway
asyl04015  Rap1 signaling pathway
asyl04218  Cellular senescence
asyl04380  Osteoclast differentiation
asyl04620  Toll-like receptor signaling pathway
asyl04664  Fc epsilon RI signaling pathway
asyl04668  TNF signaling pathway
asyl04750  Inflammatory mediator regulation of TRP channels
asyl04912  GnRH signaling pathway
asyl04935  Growth hormone synthesis, secretion and action
asyl04936  Alcoholic liver disease
asyl05014  Amyotrophic lateral sclerosis
asyl05022  Pathways of neurodegeneration - multiple diseases
asyl05132  Salmonella infection
asyl05135  Yersinia infection
asyl05145  Toxoplasmosis
asyl05161  Hepatitis B
asyl05163  Human cytomegalovirus infection
asyl05167  Kaposi sarcoma-associated herpesvirus infection
asyl05169  Epstein-Barr virus infection
asyl05170  Human immunodeficiency virus 1 infection
asyl05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
asyl05417  Lipid and atherosclerosis
asyl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:asyl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    127694765 (Map2k6)
   04015 Rap1 signaling pathway
    127694765 (Map2k6)
   04668 TNF signaling pathway
    127694765 (Map2k6)
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    127694765 (Map2k6)
 09150 Organismal Systems
  09151 Immune system
   04620 Toll-like receptor signaling pathway
    127694765 (Map2k6)
   04664 Fc epsilon RI signaling pathway
    127694765 (Map2k6)
  09152 Endocrine system
   04912 GnRH signaling pathway
    127694765 (Map2k6)
   04935 Growth hormone synthesis, secretion and action
    127694765 (Map2k6)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    127694765 (Map2k6)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    127694765 (Map2k6)
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    127694765 (Map2k6)
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    127694765 (Map2k6)
   05161 Hepatitis B
    127694765 (Map2k6)
   05163 Human cytomegalovirus infection
    127694765 (Map2k6)
   05167 Kaposi sarcoma-associated herpesvirus infection
    127694765 (Map2k6)
   05169 Epstein-Barr virus infection
    127694765 (Map2k6)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    127694765 (Map2k6)
   05135 Yersinia infection
    127694765 (Map2k6)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    127694765 (Map2k6)
  09164 Neurodegenerative disease
   05014 Amyotrophic lateral sclerosis
    127694765 (Map2k6)
   05022 Pathways of neurodegeneration - multiple diseases
    127694765 (Map2k6)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    127694765 (Map2k6)
   05418 Fluid shear stress and atherosclerosis
    127694765 (Map2k6)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    127694765 (Map2k6)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:asyl01001]
    127694765 (Map2k6)
Enzymes [BR:asyl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.12  Dual-specificity kinases (those acting on Ser/Thr and Tyr residues)
    2.7.12.2  mitogen-activated protein kinase kinase
     127694765 (Map2k6)
Protein kinases [BR:asyl01001]
 Serine/threonine kinases: STE group
  STE7 family
   127694765 (Map2k6)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr Kinase-like ABC1 Pkinase_fungal Seadorna_VP7 Choline_kinase CLP1_P Haspin_kinase DUF4344 APH
Other DBs
NCBI-GeneID: 127694765
NCBI-ProteinID: XP_052052388
LinkDB
Position
10:complement(12114137..12236664)
AA seq 334 aa
MSQSKGKKRNPGLKIPKEAFEQPQTSSTPPRDLDSKACISIGNQNFEVKADDLEPIVELG
RGAYGVVEKMHHVPSGQIMAVKRIRATVNSQEQKRLLMDLDVSMRTVDCPFTVTFYGALF
REGDVWICMELMDTSLDKFYKQVIDKGQTIPEDILGKIAVSIVKALEHLHSKLSVIHRDV
KPSNVLINTLGQVKMCDFGISGYLVDSVAKTIDAGCKPYMAPERINPELNQKGYSVKSDI
WSLGITMIELAILRFPYDSWGTPFQQLKQVVEEPSPQLPADKFSADFVDFTSQCLKKNSK
ERPTYPELMQHPFFTVHESKAADVASFVKLILGN
NT seq 1005 nt   +upstreamnt  +downstreamnt
atgtctcagtcgaaaggcaagaagcgaaaccctggccttaagattccgaaagaagcgttt
gaacaacctcagaccagttccacgccgcctcgggatttagactccaaggcttgtatatct
attggaaaccagaactttgaggtgaaggcagacgacttggagcctatagtcgagctgggt
cgaggtgcgtacggtgtggtggagaagatgcaccacgtgcccagcgggcagatcatggcg
gtgaagcggatacgggccacagttaatagccaggagcagaaacggctactgatggatctg
gatgtttcgatgaggacagtggactgcccgtttactgtgaccttctatggtgcactcttc
cgggagggcgacgtgtggatctgcatggagctcatggacacatcactagataaattctac
aaacaagttattgataaaggccaaacaattccagaggatatcttaggaaagatagcagtt
tctattgtaaaagccttagaacatttacacagtaagctctctgtgatccatcgagatgtc
aagccttctaatgtgctcattaacacattgggccaagtaaagatgtgtgactttggaatc
agtggctacctggtcgactctgttgctaaaacgatcgatgcgggttgcaaaccatacatg
gctcctgaacgaataaatccagagctcaaccagaaggggtacagcgtgaagtctgacatt
tggagtctgggcatcactatgatcgagctagccatccttcggtttccctatgattcctgg
ggaacgcccttccagcagctaaagcaggtggtggaagagccctctccacagctcccagca
gacaagttctccgccgactttgttgactttacctcacagtgcttgaagaaaaattccaaa
gaacggcctacatatccagagcttatgcaacatccatttttcactgtacatgaatccaaa
gcagcagacgtggcatcttttgtaaaactgatacttgggaactaa

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