Apodemus sylvaticus (European woodmouse): 127695362
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Entry
127695362 CDS
T10613
Symbol
Ern1
Name
(RefSeq) serine/threonine-protein kinase/endoribonuclease IRE1 isoform X1
KO
K08852
serine/threonine-protein kinase/endoribonuclease IRE1 [EC:
2.7.11.1
3.1.26.-]
Organism
asyl Apodemus sylvaticus (European woodmouse)
Pathway
asyl04140
Autophagy - animal
asyl04141
Protein processing in endoplasmic reticulum
asyl04210
Apoptosis
asyl04932
Non-alcoholic fatty liver disease
asyl05010
Alzheimer disease
asyl05012
Parkinson disease
asyl05014
Amyotrophic lateral sclerosis
asyl05016
Huntington disease
asyl05017
Spinocerebellar ataxia
asyl05022
Pathways of neurodegeneration - multiple diseases
asyl05417
Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
asyl00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
127695362 (Ern1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
127695362 (Ern1)
09143 Cell growth and death
04210 Apoptosis
127695362 (Ern1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
127695362 (Ern1)
05012 Parkinson disease
127695362 (Ern1)
05014 Amyotrophic lateral sclerosis
127695362 (Ern1)
05016 Huntington disease
127695362 (Ern1)
05017 Spinocerebellar ataxia
127695362 (Ern1)
05022 Pathways of neurodegeneration - multiple diseases
127695362 (Ern1)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
127695362 (Ern1)
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
127695362 (Ern1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
asyl01001
]
127695362 (Ern1)
Enzymes [BR:
asyl01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
127695362 (Ern1)
Protein kinases [BR:
asyl01001
]
Serine/threonine kinases: Other
IRE family
127695362 (Ern1)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
Ribonuc_2-5A
PK_Tyr_Ser-Thr
Beta-prop_ACSF4
PQQ_2
Pkinase_fungal
Kdo
APH
Motif
Other DBs
NCBI-GeneID:
127695362
NCBI-ProteinID:
XP_052053411
LinkDB
All DBs
Position
10:16496741..16586029
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AA seq
977 aa
AA seq
DB search
MPARWLLLLLSLLLSSPGPGSFGRASTVTLPETLLFVSTLDGSLHAVSKRTGSIKWTLKE
DPVLQVPTHVEEPAFLPDPNDGSLYTLGGKNNEGLTKLPFTIPELVQASPCRSSDGILYM
GKKQDIWYVIDLLTGEKQQTLSSAFADSLCPSTSLLYLGRTEYTITMYDTKTRELRWNAT
YFDYAASLPEDDVDYKMSHFVSNGDGLVVTVDSESGDVLWIQNYASPVVAFYVWQREGLR
KVVHINVAVETLRYLTFMSGEVGRITKWKYPFPKETEAKSKLTPTLYVGKYSTSLYASPS
MVHEGVAVVPRGSTLPLLEGPQTDGVTIGDKGECVITPSTDLKFDPGLKGKSKLNYLRNY
WLLIGHHETPLSASTKMLERFPNNLPKHRENVIPADSEKRSFEEVINLVDQTSDNTPTTV
SQDVEEKLPRAPAKPEAPMDSMLKDMATIILSIFLLLGWVAFIITYPLSMHQQRQLQRQQ
FQKELEKIQLLQQQELPLHPHGDLTQDPEFLDSSGLFSESSDTSSPSPSPRASNHSLHSS
SSASKAGTSPSLEQEDEDEETRMVIVGKISFCPKDVLGHGAEGTIVYKGMFDNRDVAVKR
ILPECFSFADREVQLLRESDEHPNVIRYFCTEKDRQFQYIAIELCAATLQEYVEQKDFAH
LGLEPITLLHQTTSGLAHLHSLNIVHRDLKPHNILLSMPNAHGRIKAMISDFGLCKKLAV
GRHSFSRHSGVPGTEGWIAPEMLSEDCKENPTYTVDIFSAGCVFYYVISEGNHPFGKSLQ
RQANILLGACNLDCFHSDKHEDVIARELIEKMIAMDPQQRPSAKHVLKHPFFWSLEKQLQ
FFQDVSDRIEKEALDGPIVRQLERGGRAVVKMDWRENITVPLQTDLRKFRTYKGGSVRDL
LRAMRNKKHHYRELPAEVQETLGSIPDDFVRYFTSRFPRLLSHTYQAMELCRHERLFQTY
YWHEPTEPQPPVIPDAL
NT seq
2934 nt
NT seq
+upstream
nt +downstream
nt
atgccggcccggtggttgttgctcctactgtcgctgctgctatcgtcgcccggccccggg
agttttggaagagccagcacagtaacactgcctgaaaccttgttgtttgtttcaaccctg
gatggaagtttgcatgctgtcagcaagaggacaggctccatcaagtggactttaaaagaa
gatccagtcctgcaggtcccaacacacgtggaagagcctgctttcctcccagatcccaat
gatggcagtctgtacacgcttggaggcaagaataatgaaggcctgacgaaacttcccttt
actatcccagaattggttcaggcatccccatgccgaagttcagatgggatcctctacatg
ggtaaaaagcaagacatttggtatgttatcgacctcctgactggcgaaaagcagcagact
ttgtcatcagcctttgctgatagtctctgcccgtcaacttcccttctatatcttggacgg
acagaatacaccatcaccatgtatgacaccaagacccgggagctccgctggaatgccacc
tattttgactatgcagcctcactgcctgaggatgacgtggactacaagatgtcccacttt
gtgtccaatggcgatggactggtggtaactgtggacagtgaatccggggatgtcttgtgg
atccaaaactatgcctctcctgtggtggccttctacgtctggcagcgggagggcctgaga
aaggtggtgcacatcaacgttgctgtggagactcttcgctacttgaccttcatgtctggg
gaagtggggcgcatcaccaagtggaagtatccattccccaaggagacggaggccaagagc
aagctgacgcctactctgtacgttgggaagtattccaccagcctctatgcctctccctca
atggtgcatgagggggttgctgtcgtgcctcgaggcagcactcttcctttgctggaaggt
ccccagacagatggtgtcaccattggagacaaaggagagtgtgtgatcactcccagcaca
gacctcaagtttgatcctggactcaaagggaagagcaagctgaattacttgaggaattac
tggcttctcataggacaccatgaaacgcctctgtctgcatccaccaagatgctggagaga
tttcctaacaacctgcccaaacatcgagaaaatgtgattcctgctgactcggaaaaaagg
agctttgaagaagttatcaacctagttgaccagacatcagacaacacaccaaccaccgta
tctcaggatgtggaagagaagctgccccgtgcccctgccaagccggaggcccccatggac
tccatgctcaaggacatggctactatcatcctgagcatcttcctgctgcttgggtgggtg
gcattcatcatcacttaccccctgagcatgcatcagcagcgccagctccagcgccaacag
ttccagaaggaactagagaaaattcagctcctgcagcagcaggagctgcccttgcaccca
cacggagaccttacccaggaccctgagttcctggattcatctggcctcttctcagagagc
tcagacaccagcagccccagcccatcccccagagcctccaaccactccctccactccagc
agctctgcctccaaggccggcaccagcccctccctggagcaggaagatgaggatgaggaa
accagaatggtgattgttgggaaaatttcattctgccccaaggatgtcctgggccatgga
gctgagggcacaattgtatacaaagggatgtttgacaaccgtgatgtggctgtgaagagg
atcctccctgagtgttttagctttgccgaccgtgaggtccaactgcttcgagaatcggat
gagcaccccaatgtgatccgctacttttgcacagagaaggaccggcagttccagtacatc
gccatcgagctgtgtgcggctactctgcaagagtatgtggagcagaaggacttcgcccac
cttggcctagagcctatcaccttgcttcatcagaccacctcaggcctggcacacctgcat
tctctcaacattgttcacagagacctgaagccccacaacattctcctctccatgcccaat
gcacatggcaggataaaggcgatgatctctgacttcggcctctgcaagaagctggcagtg
ggcaggcacagcttcagccgtcactcaggggtgcctggcactgagggttggatagcccca
gagatgctgagtgaagactgtaaggagaaccctacctacacagtggacatcttctctgca
ggctgtgtgttttactatgtcatctctgagggcaaccatccttttggcaaatccttacag
cggcaggccaacatcctactgggtgcctgcaaccttgactgcttccactcagacaagcac
gaggacgtcattgctcgggaactgatagagaagatgatcgccatggaccctcagcagcga
ccctctgcaaagcatgtgctgaaacacccattcttctggagcctggaaaagcagctccag
tttttccaggatgtgagtgaccgaatagaaaaggaggctttggacggcccgatcgtacgg
cagttggagagaggcgggagagcagtggtcaagatggactggagggagaacatcactgtc
cccctgcagacagatctgcgcaaattcagaacctacaaaggtggctctgtcagagatctc
ctccgagccatgagaaataagaaacaccactaccgggagctccctgcggaggttcaggag
acgctgggctccatcccggatgactttgtgcgctacttcacgtcccgcttcccccgcctc
ctctcccacacctaccaagccatggagctgtgcagacatgagagactcttccagacctac
tactggcatgagcccacagagccccagcctccagtgatcccagatgccctctga
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