KEGG   Apodemus sylvaticus (European woodmouse): 127697194
Entry
127697194         CDS       T10613                                 
Symbol
Akt3
Name
(RefSeq) RAC-gamma serine/threonine-protein kinase isoform X1
  KO
K04456  RAC serine/threonine-protein kinase [EC:2.7.11.1]
Organism
asyl  Apodemus sylvaticus (European woodmouse)
Pathway
asyl01521  EGFR tyrosine kinase inhibitor resistance
asyl01522  Endocrine resistance
asyl01524  Platinum drug resistance
asyl04010  MAPK signaling pathway
asyl04012  ErbB signaling pathway
asyl04014  Ras signaling pathway
asyl04015  Rap1 signaling pathway
asyl04022  cGMP-PKG signaling pathway
asyl04024  cAMP signaling pathway
asyl04062  Chemokine signaling pathway
asyl04066  HIF-1 signaling pathway
asyl04068  FoxO signaling pathway
asyl04071  Sphingolipid signaling pathway
asyl04072  Phospholipase D signaling pathway
asyl04140  Autophagy - animal
asyl04150  mTOR signaling pathway
asyl04151  PI3K-Akt signaling pathway
asyl04152  AMPK signaling pathway
asyl04210  Apoptosis
asyl04211  Longevity regulating pathway
asyl04213  Longevity regulating pathway - multiple species
asyl04218  Cellular senescence
asyl04261  Adrenergic signaling in cardiomyocytes
asyl04370  VEGF signaling pathway
asyl04371  Apelin signaling pathway
asyl04380  Osteoclast differentiation
asyl04510  Focal adhesion
asyl04517  IgSF CAM signaling
asyl04518  Integrin signaling
asyl04550  Signaling pathways regulating pluripotency of stem cells
asyl04611  Platelet activation
asyl04613  Neutrophil extracellular trap formation
asyl04620  Toll-like receptor signaling pathway
asyl04625  C-type lectin receptor signaling pathway
asyl04630  JAK-STAT signaling pathway
asyl04660  T cell receptor signaling pathway
asyl04662  B cell receptor signaling pathway
asyl04664  Fc epsilon RI signaling pathway
asyl04666  Fc gamma R-mediated phagocytosis
asyl04668  TNF signaling pathway
asyl04722  Neurotrophin signaling pathway
asyl04725  Cholinergic synapse
asyl04728  Dopaminergic synapse
asyl04810  Regulation of actin cytoskeleton
asyl04910  Insulin signaling pathway
asyl04914  Progesterone-mediated oocyte maturation
asyl04915  Estrogen signaling pathway
asyl04917  Prolactin signaling pathway
asyl04919  Thyroid hormone signaling pathway
asyl04920  Adipocytokine signaling pathway
asyl04922  Glucagon signaling pathway
asyl04923  Regulation of lipolysis in adipocytes
asyl04926  Relaxin signaling pathway
asyl04929  GnRH secretion
asyl04931  Insulin resistance
asyl04932  Non-alcoholic fatty liver disease
asyl04933  AGE-RAGE signaling pathway in diabetic complications
asyl04935  Growth hormone synthesis, secretion and action
asyl04936  Alcoholic liver disease
asyl04973  Carbohydrate digestion and absorption
asyl05010  Alzheimer disease
asyl05017  Spinocerebellar ataxia
asyl05132  Salmonella infection
asyl05135  Yersinia infection
asyl05142  Chagas disease
asyl05145  Toxoplasmosis
asyl05152  Tuberculosis
asyl05160  Hepatitis C
asyl05161  Hepatitis B
asyl05162  Measles
asyl05163  Human cytomegalovirus infection
asyl05164  Influenza A
asyl05165  Human papillomavirus infection
asyl05166  Human T-cell leukemia virus 1 infection
asyl05167  Kaposi sarcoma-associated herpesvirus infection
asyl05168  Herpes simplex virus 1 infection
asyl05169  Epstein-Barr virus infection
asyl05170  Human immunodeficiency virus 1 infection
asyl05200  Pathways in cancer
asyl05205  Proteoglycans in cancer
asyl05207  Chemical carcinogenesis - receptor activation
asyl05208  Chemical carcinogenesis - reactive oxygen species
asyl05210  Colorectal cancer
asyl05211  Renal cell carcinoma
asyl05212  Pancreatic cancer
asyl05213  Endometrial cancer
asyl05214  Glioma
asyl05215  Prostate cancer
asyl05218  Melanoma
asyl05220  Chronic myeloid leukemia
asyl05221  Acute myeloid leukemia
asyl05222  Small cell lung cancer
asyl05223  Non-small cell lung cancer
asyl05224  Breast cancer
asyl05225  Hepatocellular carcinoma
asyl05226  Gastric cancer
asyl05230  Central carbon metabolism in cancer
asyl05231  Choline metabolism in cancer
asyl05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
asyl05415  Diabetic cardiomyopathy
asyl05417  Lipid and atherosclerosis
asyl05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:asyl00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    127697194 (Akt3)
   04012 ErbB signaling pathway
    127697194 (Akt3)
   04014 Ras signaling pathway
    127697194 (Akt3)
   04015 Rap1 signaling pathway
    127697194 (Akt3)
   04370 VEGF signaling pathway
    127697194 (Akt3)
   04371 Apelin signaling pathway
    127697194 (Akt3)
   04630 JAK-STAT signaling pathway
    127697194 (Akt3)
   04668 TNF signaling pathway
    127697194 (Akt3)
   04066 HIF-1 signaling pathway
    127697194 (Akt3)
   04068 FoxO signaling pathway
    127697194 (Akt3)
   04072 Phospholipase D signaling pathway
    127697194 (Akt3)
   04071 Sphingolipid signaling pathway
    127697194 (Akt3)
   04024 cAMP signaling pathway
    127697194 (Akt3)
   04022 cGMP-PKG signaling pathway
    127697194 (Akt3)
   04151 PI3K-Akt signaling pathway
    127697194 (Akt3)
   04152 AMPK signaling pathway
    127697194 (Akt3)
   04150 mTOR signaling pathway
    127697194 (Akt3)
  09133 Signaling molecules and interaction
   04517 IgSF CAM signaling
    127697194 (Akt3)
   04518 Integrin signaling
    127697194 (Akt3)
 09140 Cellular Processes
  09141 Transport and catabolism
   04140 Autophagy - animal
    127697194 (Akt3)
  09143 Cell growth and death
   04210 Apoptosis
    127697194 (Akt3)
   04218 Cellular senescence
    127697194 (Akt3)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    127697194 (Akt3)
   04550 Signaling pathways regulating pluripotency of stem cells
    127697194 (Akt3)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    127697194 (Akt3)
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    127697194 (Akt3)
   04613 Neutrophil extracellular trap formation
    127697194 (Akt3)
   04620 Toll-like receptor signaling pathway
    127697194 (Akt3)
   04625 C-type lectin receptor signaling pathway
    127697194 (Akt3)
   04660 T cell receptor signaling pathway
    127697194 (Akt3)
   04662 B cell receptor signaling pathway
    127697194 (Akt3)
   04664 Fc epsilon RI signaling pathway
    127697194 (Akt3)
   04666 Fc gamma R-mediated phagocytosis
    127697194 (Akt3)
   04062 Chemokine signaling pathway
    127697194 (Akt3)
  09152 Endocrine system
   04910 Insulin signaling pathway
    127697194 (Akt3)
   04922 Glucagon signaling pathway
    127697194 (Akt3)
   04923 Regulation of lipolysis in adipocytes
    127697194 (Akt3)
   04920 Adipocytokine signaling pathway
    127697194 (Akt3)
   04929 GnRH secretion
    127697194 (Akt3)
   04915 Estrogen signaling pathway
    127697194 (Akt3)
   04914 Progesterone-mediated oocyte maturation
    127697194 (Akt3)
   04917 Prolactin signaling pathway
    127697194 (Akt3)
   04926 Relaxin signaling pathway
    127697194 (Akt3)
   04935 Growth hormone synthesis, secretion and action
    127697194 (Akt3)
   04919 Thyroid hormone signaling pathway
    127697194 (Akt3)
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    127697194 (Akt3)
  09154 Digestive system
   04973 Carbohydrate digestion and absorption
    127697194 (Akt3)
  09156 Nervous system
   04725 Cholinergic synapse
    127697194 (Akt3)
   04728 Dopaminergic synapse
    127697194 (Akt3)
   04722 Neurotrophin signaling pathway
    127697194 (Akt3)
  09158 Development and regeneration
   04380 Osteoclast differentiation
    127697194 (Akt3)
  09149 Aging
   04211 Longevity regulating pathway
    127697194 (Akt3)
   04213 Longevity regulating pathway - multiple species
    127697194 (Akt3)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    127697194 (Akt3)
   05205 Proteoglycans in cancer
    127697194 (Akt3)
   05207 Chemical carcinogenesis - receptor activation
    127697194 (Akt3)
   05208 Chemical carcinogenesis - reactive oxygen species
    127697194 (Akt3)
   05230 Central carbon metabolism in cancer
    127697194 (Akt3)
   05231 Choline metabolism in cancer
    127697194 (Akt3)
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    127697194 (Akt3)
  09162 Cancer: specific types
   05210 Colorectal cancer
    127697194 (Akt3)
   05212 Pancreatic cancer
    127697194 (Akt3)
   05225 Hepatocellular carcinoma
    127697194 (Akt3)
   05226 Gastric cancer
    127697194 (Akt3)
   05214 Glioma
    127697194 (Akt3)
   05221 Acute myeloid leukemia
    127697194 (Akt3)
   05220 Chronic myeloid leukemia
    127697194 (Akt3)
   05218 Melanoma
    127697194 (Akt3)
   05211 Renal cell carcinoma
    127697194 (Akt3)
   05215 Prostate cancer
    127697194 (Akt3)
   05213 Endometrial cancer
    127697194 (Akt3)
   05224 Breast cancer
    127697194 (Akt3)
   05222 Small cell lung cancer
    127697194 (Akt3)
   05223 Non-small cell lung cancer
    127697194 (Akt3)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    127697194 (Akt3)
   05170 Human immunodeficiency virus 1 infection
    127697194 (Akt3)
   05161 Hepatitis B
    127697194 (Akt3)
   05160 Hepatitis C
    127697194 (Akt3)
   05164 Influenza A
    127697194 (Akt3)
   05162 Measles
    127697194 (Akt3)
   05168 Herpes simplex virus 1 infection
    127697194 (Akt3)
   05163 Human cytomegalovirus infection
    127697194 (Akt3)
   05167 Kaposi sarcoma-associated herpesvirus infection
    127697194 (Akt3)
   05169 Epstein-Barr virus infection
    127697194 (Akt3)
   05165 Human papillomavirus infection
    127697194 (Akt3)
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    127697194 (Akt3)
   05135 Yersinia infection
    127697194 (Akt3)
   05152 Tuberculosis
    127697194 (Akt3)
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    127697194 (Akt3)
   05142 Chagas disease
    127697194 (Akt3)
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    127697194 (Akt3)
   05017 Spinocerebellar ataxia
    127697194 (Akt3)
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    127697194 (Akt3)
   05418 Fluid shear stress and atherosclerosis
    127697194 (Akt3)
   05415 Diabetic cardiomyopathy
    127697194 (Akt3)
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    127697194 (Akt3)
   04932 Non-alcoholic fatty liver disease
    127697194 (Akt3)
   04931 Insulin resistance
    127697194 (Akt3)
   04933 AGE-RAGE signaling pathway in diabetic complications
    127697194 (Akt3)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    127697194 (Akt3)
   01524 Platinum drug resistance
    127697194 (Akt3)
   01522 Endocrine resistance
    127697194 (Akt3)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:asyl01001]
    127697194 (Akt3)
Enzymes [BR:asyl01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.1  non-specific serine/threonine protein kinase
     127697194 (Akt3)
Protein kinases [BR:asyl01001]
 Serine/threonine kinases: AGC group
  AKT/PKB family
   127697194 (Akt3)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PH Pkinase_C Kinase-like PH_20 ABC1
Other DBs
NCBI-GeneID: 127697194
NCBI-ProteinID: XP_052056104
LinkDB
Position
12:complement(84448934..84727524)
AA seq 479 aa
MSDVTIVKEGWVQKRGEYIKNWRPRYFLLKTDGSFIGYKEKPQDVDLPYPLNNFSVAKCQ
LMKTERPKPNTFIIRCLQWTTVIERTFHVDTPEEREEWTEAIQAVADRLQRQEEERMNCS
PTSQIDNIGEEEMDASTTHHKRKTMNDFDYLKLLGKGTFGKVILVREKASGKYYAMKILK
KEVIIAKDEVAHTLTESRVLKNTRHPFLTSLKYSFQTKDRLCFVMEYVNGGELFFHLSRE
RVFSEDRTRFYGAEIVSALDYLHSGKIVYRDLKLENLMLDKDGHIKITDFGLCKEGITDA
ATMKTFCGTPEYLAPEVLEDNDYGRAVDWWGLGVVMYEMMCGRLPFYNQDHEKLFELILM
EDIKFPRTLSSDAKSLLSGLLIKDPNKRLGGGPDDAKEIMRHSFFSGVNWQDVYDKKLVP
PFKPQVTSETDTRYFDEEFTAQTITITPPEKYDDDGMDGMDNERRPHFPQFSYSASGRE
NT seq 1440 nt   +upstreamnt  +downstreamnt
atgagcgatgttaccattgtgaaagaaggttgggttcagaagaggggagaatatataaaa
aattggaggccaagatacttccttttgaagacagatggctcattcataggctataaggag
aaacctcaagatgtggacttaccttatcccctcaacaacttctcagtggcaaaatgtcag
ttaatgaaaacagagcgaccaaagccaaatacatttattatcagatgtcttcagtggacc
actgtaatagagagaacatttcatgtagatacaccagaggaaagagaagaatggacagaa
gctatccaagctgtagccgaccgactgcagaggcaagaagaagagaggatgaattgtagt
ccaacctcacagattgataatataggagaggaagagatggatgcgtctacaacccatcat
aaaagaaagacaatgaatgattttgactatttgaaactactaggtaaaggcacgtttggg
aaggttattttggttcgagagaaggcaagtggaaaatactatgctatgaagattctgaaa
aaagaagtcattattgcaaaggatgaagtggcacacactcttactgaaagcagagtacta
aagaacaccagacatccatttttaacatccttgaaatattccttccagacaaaagatcgt
ttgtgttttgtgatggaatatgttaatggtggagagctgtttttccatttgtcgagagag
cgggtgttctctgaggaccgcacacgtttctatggtgcagaaattgtctctgctttggac
tatctacattctggaaagattgtgtaccgtgatctcaagttggagaatctgatgctagat
aaggatggccatataaaaatcacggattttggactttgcaaagaagggatcacagatgcg
gctaccatgaagacattctgtggcacaccagagtatctggcaccagaggtattagaagat
aatgactatggtcgagctgtggattggtggggcctcggtgttgtcatgtatgaaatgatg
tgtgggaggttgcctttctacaaccaggatcatgagaaactctttgaattaatactaatg
gaagatattaaattcccccgaacactctcttcagatgcaaaatcattgctttcagggctc
ttgataaaggatccaaataaacgccttggtggagggcccgatgatgcaaaggaaatcatg
aggcatagctttttttctggagtaaactggcaagatgtatacgacaaaaagcttgtacct
ccttttaagcctcaagtcacatctgaaacagacaccagatattttgatgaagaattcaca
gctcagactattacaataacaccacctgaaaagtatgacgatgacggcatggacggcatg
gataacgagcggcggccacacttccctcagttctcctactctgcaagcggacgcgaatga

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