Caldicellulosiruptor bescii: Athe_0507
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Entry
Athe_0507 CDS
T00857
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family protein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
ate
Caldicellulosiruptor bescii
Pathway
ate00290
Valine, leucine and isoleucine biosynthesis
ate00620
Pyruvate metabolism
ate01100
Metabolic pathways
ate01110
Biosynthesis of secondary metabolites
ate01210
2-Oxocarboxylic acid metabolism
ate01230
Biosynthesis of amino acids
Module
ate_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
ate00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
Athe_0507
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
Athe_0507
Enzymes [BR:
ate01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
Athe_0507
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Paralog
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Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Ecm33
Motif
Other DBs
NCBI-ProteinID:
ACM59633
UniProt:
B9MNV4
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Position
576528..578108
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AA seq
526 aa
AA seq
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MENNKTIIIYDSTLRDGAQAGGISYTLEDKLKIVERLDKFGVKFIEAGNPGSNIKDQEFF
ARVKKMRLKNAKLIAFGSTRRVGINVKDDPNIQSLIAADTEAVAIFGKSWDFHVKEVLKT
TEDENLQMIYDTIKYLKSLGKYVVFDAEHFFDGYKNNKKYALETLKVAKEAGADSLDLCD
TNGGTFPMDVYNITKEVVEMFPGTMIGIHCHNDTGMAVANSVMAVLAGARQVQGTINGYG
ERCGNADLITLIPNLQLKLGFKCVPDENIKHLTSLSRYVAEIANMIPNERAPYVGAYAFT
HKAGMHIDAVKKNPASFEHINPEIVGNTRRIVLSEVAGRATILDKIREIDPTVTKDSPVT
KEIIDELKRLENEGYQFESAEASFEMLIRKKLGLYQPFFTLKEFKVLINEPAVEYSSSAI
VKIAVDGVTAITAAEGDGPVHALDSALRKALEKFYPELKEVHLVDYKVRVLNAETATAAK
VRVLIESTDGKDTWTTVGVSTDIVNASWIALVDSLEYKLCKEKVGK
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
gtggaaaataataagaccatcatcatctatgactcaaccttaagagacggtgctcaggct
ggtggaatttcatatactctggaagataagctcaagattgtagagaggcttgacaaattt
ggtgtgaaatttatcgaagcagggaatcccggttctaacatcaaagaccaggaatttttt
gcaagagttaaaaagatgagattgaaaaacgcaaagcttatcgcctttggttcaacaagg
cgagtggggattaacgtgaaagatgaccctaacattcagtcactcattgcggctgatacc
gaagctgttgcaatctttggcaagtcatgggattttcatgttaaagaggtcttgaaaaca
acagaggatgaaaatcttcagatgatttatgatactataaaatatttaaagtcattgggg
aagtatgttgtatttgatgcagagcacttttttgatggttataaaaataacaaaaagtac
gctttggagactttaaaggttgcaaaagaagcaggtgcagactctttggacctgtgcgat
acaaatggcggtactttcccaatggatgtttacaacatcacgaaagaagttgttgagatg
tttcctgggacgatgattggaattcactgtcataacgacacaggcatggctgttgcaaac
tcagtcatggcggttttggcaggagctcgtcaggttcaggggactataaacggatatggt
gagagatgtggaaacgcagaccttattacactcataccaaatcttcagctaaagcttggc
tttaaatgtgtaccagatgagaacataaaacacctgacatcactttcaaggtatgttgca
gagattgccaacatgattccaaacgagcgcgcaccatatgttggagcttatgcgtttact
cacaaggctggtatgcacattgatgctgtcaagaaaaatccagcttcgtttgagcatatt
aaccctgagattgttggaaacacaagaagaatagtactgtctgaggttgcaggaagggct
acaattcttgacaagattcgcgagattgacccgacagttacaaaagactcacctgtcaca
aaagagattattgatgagctaaagcgtcttgaaaatgaagggtatcagtttgagtctgca
gaggcttcatttgagatgttaattagaaaaaaactgggactttaccagccgttctttact
ctcaaagaatttaaagttctcattaatgaaccggcagtagagtacagctcatctgcaatt
gtaaagattgcggtagatggggttacagcaatcactgctgcagaaggtgatggtcctgtt
catgctttagatagtgctttgagaaaggcattggaaaagttctacccagagctcaaagag
gttcatcttgttgactacaaagtaagagtgctcaacgccgagactgcaactgctgcaaag
gtaagggttctgattgagtcaacagacggcaaagacacatggacaactgtaggtgtttca
accgacattgtaaatgcaagctggattgcacttgttgactcactggagtataagctttgc
aaagaaaaagtgggaaaataa
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