Aquincola tertiaricarbonis: MW290_19625
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Entry
MW290_19625 CDS
T08158
Symbol
purL
Name
(GenBank) phosphoribosylformylglycinamidine synthase
KO
K01952
phosphoribosylformylglycinamidine synthase [EC:
6.3.5.3
]
Organism
ater
Aquincola tertiaricarbonis
Pathway
ater00230
Purine metabolism
ater01100
Metabolic pathways
ater01110
Biosynthesis of secondary metabolites
Module
ater_M00048
De novo purine biosynthesis, PRPP + glutamine => IMP
Brite
KEGG Orthology (KO) [BR:
ater00001
]
09100 Metabolism
09104 Nucleotide metabolism
00230 Purine metabolism
MW290_19625 (purL)
Enzymes [BR:
ater01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.5 Carbon-nitrogen ligases with glutamine as amido-N-donor
6.3.5.3 phosphoribosylformylglycinamidine synthase
MW290_19625 (purL)
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Gene cluster
GFIT
Motif
Pfam:
GATase_5
FGAR-AT_PurM_N-like
AIRS_C
FGAR-AT_N
FGAR-AT_linker
Motif
Other DBs
NCBI-ProteinID:
URI11171
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All DBs
Position
2:1172150..1176148
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AA seq
1332 aa
AA seq
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MAAVLPTSSKHLLHFEGGNALSPFRAQALLARLAAVSPRITGVAARHVHWVWTDAELPAA
DRDKLAALLTYGDAYAGPNDGPAIVVMPRLGTVSPWASKATDIAHNCGLGIHRVERVTEY
RLTLKTGLLGGSKPLAEAELQAAALLLHDRMTESVAFDRAAAAHLFDEQPAKPLVHVDVL
GAGRQALVQANAEFGLALSDDEVDYLVNAFTGLGRNPSDVELMMFAQANSEHCRHKIFNA
DFTIDGERQPVSMFGMIRHTEKTSPQATVIAYNDNAAVMEGGEIERWSPEGYTNAPAYTA
RRELSHVLMKVETHNHPTAISPFPGASTGAGGEIRDEGATGRGARPKAGLTGFSVSNLQL
PDTNEPWERQPYGKPEHIASALDIMIEGPLGGAAFNNEFGRPNLGGYFRVFEQTVDGQRR
GYHKPIMIAGGLGAIRADQTQKLPFGPGTLLIQLGGPGMRIGMGGGAASSMAAGTNVAAL
DFDSVQRGNPEIERRAQEVINHCWALGDANPIMAIHDVGAGGISNAFPELVDGAGQGATF
DLRKVPLEETGLAPKEIWCNESQERYVIALDPAGLPLFEAMAARERCPFAVVGVATSDRE
LVLEDGPGGERVIDMPMDVLLGKPPKMHRDVKRLPRTLAALDLTGVSLEQAALDVLRHPT
VASKRFLITIGDRSVGGLSHRDQMVGPWQVPVADVAVTLADFAGFRGEAMAMGERTPLAV
LDAPASGRMAVAESITNLLAAPIDLPRVKLSCNWMAACGEPGEDAALYDTVKAVGLELCP
ALGIGVPVGKDSLSMRTRWSEGAETKQVVAPVSLVVTAFVTLDDVRGTLTPQLQAGDTTL
ILIDLGQGRRRMGGSILAQTLQQFGDAVPDLDDPAQLKALVQAINALRSAGQLLAYHDRG
DGGLWATVCEMAFAGHLGVSLNVDLLVTDSDGISDSRAEYGDSKNWATQVGERRNELTLQ
ALFNEELGAVIQVKSADRDAVMATLRAHGLSRHSHVIGKPNSKGVVEIYRDAKAVYSAPL
QQLHQAWDEVSWRIARLRDNPACADAEHAAVGQPDDTGLHQHLSFDPQQALPLVGIGGAK
PKMAILREQGVNSHVEMAYAMSLAGFETFDVHMSDLQAGRARLDQFQGFVACGGFSYGDT
LGAGEGWARSILFNPQLAEAFAAFFGRTDTLALGVCNGCQMLAALSSIIPGADAWPKFTR
NKSEQFEARLSMVEVLQSPSVFFTGMAGSRLPIVVSHGEGFADFSQRGDAARVQRAMRYV
DHRGQPTEAYPANPNGSPGGLTSVTTADGRFTALMPHPERVFRNVQMSWAAGDVSAHSPW
LQMFHNARRALG
NT seq
3999 nt
NT seq
+upstream
nt +downstream
nt
atggctgccgtcttgcccacttcctccaagcatcttttgcatttcgaaggcggcaacgcc
ttgtcgcccttccgtgcacaagcgttgctggcccggcttgcggccgtcagcccgcgcatc
acgggcgtcgccgcccgccacgtgcactgggtgtggaccgacgccgaactgcccgccgcc
gaccgcgacaaactggccgcgctgctgacctacggcgacgcctacgcaggccccaacgac
ggcccggccatcgtggtgatgccgcgactgggcaccgtcagcccctgggccagcaaggcc
accgacatcgcccacaactgcggcctgggcatccaccgggtggaacgcgtcaccgaatac
cggctgacgctcaagaccggcctgctgggcggcagcaagccgctggccgaggccgagctg
caggccgccgcgctgctgctgcacgaccgcatgaccgagagcgtggccttcgaccgcgcg
gccgccgcccacttgttcgacgagcagccggccaagccgctggtgcatgtggacgtgctg
ggcgcgggccgccaggcgctggtgcaggctaatgccgaatttggcctggcgctgtcggac
gacgaggtggactacctcgtcaacgccttcaccggcctgggccgcaaccccagcgacgtc
gagctgatgatgttcgcgcaggccaactccgagcactgccgccacaagatcttcaacgcc
gacttcaccatcgacggcgagcgtcagccggtgtcgatgttcggcatgatccgccacacc
gagaagaccagcccgcaggccaccgtcatcgcctacaacgacaacgcggcggtgatggaa
ggcggcgagatcgagcgctggtcgcccgagggctacaccaacgccccggcctacaccgcc
cggcgcgagctttcgcacgtgctgatgaaggtggaaacccacaaccacccgacggccatc
tcgcctttcccgggcgcttccaccggcgcgggcggcgaaatccgcgatgaaggcgccacc
ggccgcggcgcacggcccaaggcgggcctgacgggcttttcggtcagcaacctgcagctg
cccgacaccaacgagccctgggagcgccagccctacggcaagcccgagcacatcgccagc
gcgctggacatcatgatcgaaggcccgctgggcggcgccgcgttcaacaacgagttcggc
cggcccaacctgggcggctacttccgcgtgttcgagcagacggtggacggccagcggcgc
ggctaccacaagcccatcatgatcgcgggcggcctgggcgccatccgcgccgaccagacc
cagaaactgcccttcggccccggcaccctgctcatccagctgggcggccccggcatgcgc
atcggcatgggcggcggcgccgccagctcgatggcggccggcaccaacgtggcggcgctg
gacttcgactcggtgcagcgtggcaacccggaaatcgaacggcgtgcgcaggaggtgatc
aaccactgctgggcgctgggtgatgccaaccccatcatggccatccacgacgtgggcgcg
ggcggcatcagcaacgccttccccgagctggtggacggcgccggccagggcgccaccttc
gacctgcgcaaggtgccgctggaagaaaccggcctggcgcccaaggaaatctggtgcaac
gaaagccaggagcgctacgtcatcgcgctcgacccggccggcctgcctctgttcgaggcc
atggccgcacgcgagcgctgccccttcgcggtggtgggcgtggccaccagcgaccgtgag
ctggtgctggaagacggccccggcggtgagcgcgtgatcgacatgccgatggacgtgctg
ctgggcaagccgcccaagatgcaccgtgacgtcaagcgcctgccgcgcacgctggcggcg
ctggacctcaccggcgtgtcgctggaacaggcggcactggacgtgctgcgccaccccacc
gtggccagcaagcgcttcctgatcaccatcggtgaccgcagcgtgggtggcctcagccac
cgtgaccagatggtgggtccctggcaggtgccggtggccgacgtggcggtgacgctggcc
gacttcgccggcttccgcggcgaggccatggccatgggcgaacgcacgccgctggcggtg
ctggacgcaccggcctcgggccgcatggcggtggccgagtccatcaccaacctgctggcc
gcgcccatcgacctgccgcgcgtcaagctcagctgcaactggatggccgcctgcggcgag
ccgggtgaagacgccgctttgtacgacaccgtcaaggccgtgggcctggaactgtgcccg
gcgctgggcatcggcgtgccggtgggcaaggattcgctgtccatgcgcacccgctggagc
gaaggcgccgaaaccaaacaggtggtggccccggtgtcgctggtggtcaccgccttcgtc
acgctcgatgacgtgcgcggcaccctgacgccgcagctgcaggccggcgacaccacgctg
atcctgatcgacctgggccagggccggcgccgcatgggcggctccatcctggcgcagacg
ctgcagcagttcggcgatgcggtgcccgacctggacgaccccgcgcagctgaaggcgctg
gtgcaggccatcaacgcgctgcgcagcgccggccagctgctggcctaccacgaccgtggc
gacggcggcctgtgggccacggtgtgcgagatggcctttgccggccacctgggcgtgagc
ctgaacgtcgacctgctggtgaccgacagcgacggcatcagcgacagccgcgccgaatat
ggcgactcgaagaattgggccacccaggtcggcgagcgccgcaacgagctgacgctgcag
gcgctgttcaacgaggagctgggcgccgtcatccaggtgaagtcggccgaccgcgacgcg
gtgatggccaccctgcgcgcccacggcctcagccgccacagccatgtgatcggcaagccg
aacagcaagggcgtggtggagatctaccgcgatgccaaggccgtttacagcgcgccgctg
cagcagctgcaccaggcctgggacgaggtgagctggcgcattgcgcggctgcgcgacaac
ccggcctgtgccgatgccgagcatgccgccgtcggccagcccgacgacaccggcctgcac
cagcacctgagcttcgacccgcagcaggccttgccgctggtgggcatcggcggcgccaag
ccgaagatggccatcctgcgcgagcagggcgtcaacagccacgtcgagatggcctatgcg
atgtcgctggccggcttcgagaccttcgacgtgcacatgagcgacctgcaggccggccgc
gcgcggctggaccagttccagggcttcgtggcctgcggcggcttcagctacggcgacacg
ctgggcgcgggtgaaggctgggcgcggtccatcctgttcaatccgcagctggccgaggcc
tttgccgccttcttcggccgcaccgacacgctggcgctgggcgtgtgcaacggctgccag
atgctggccgcgctgtcgtccatcatcccgggcgccgatgcctggcccaagttcacccgc
aacaagagcgagcagttcgaggcgcggctgtcgatggtggaagtgctgcaaagccccagc
gtgttcttcaccggcatggccggcagccgcctgcccatcgtggtgtcgcacggcgagggc
tttgccgacttctcgcagcgcggcgacgcggcgcgggtgcagcgcgcgatgcgatacgtc
gaccaccgcggccagccgaccgaagcctacccggccaaccccaacggcagtccgggcggc
ctcacctcggtgaccacggccgacggtcgcttcaccgcgctgatgccccaccccgagcgc
gtcttccgcaacgtgcagatgagctgggctgccggcgacgtctctgcccacagcccgtgg
ctgcagatgttccacaacgcgcgcagggcgttgggctga
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