Amycolatopsis thermalba: L1857_03090
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Entry
L1857_03090 CDS
T08681
Symbol
pdhA
Name
(GenBank) pyruvate dehydrogenase (acetyl-transferring) E1 component subunit alpha
KO
K00166
2-oxoisovalerate dehydrogenase E1 component subunit alpha [EC:
1.2.4.4
]
Organism
athm
Amycolatopsis thermalba
Pathway
athm00280
Valine, leucine and isoleucine degradation
athm00640
Propanoate metabolism
athm00785
Lipoic acid metabolism
athm01100
Metabolic pathways
athm01110
Biosynthesis of secondary metabolites
athm01210
2-Oxocarboxylic acid metabolism
Module
athm_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
athm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
L1857_03090 (pdhA)
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
L1857_03090 (pdhA)
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
L1857_03090 (pdhA)
Enzymes [BR:
athm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
L1857_03090 (pdhA)
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Motif
Pfam:
E1_dh
TPP_enzyme_C
Motif
Other DBs
NCBI-ProteinID:
UQS21879
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Position
complement(614278..615486)
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AA seq
402 aa
AA seq
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MPSPEQWTHPEPGEGPAAQAAQPSREQVIAGLRNTDAGGAEVTQLLTPEGERIASPQFDR
YISDVDPEALRGLYRDMVLVRRADREANAMQRQGQLGIWVPLLGQEAAQVGSGRALKPQD
MAFPSYREHGVAYTRGVDFKELLGIFRCTDHGGWDFQAHGFHPYTIVIGNQVLNAAGYAM
GQKFEGKVGDDDGEATIVYFGDGATSQGDVHEGFVWAAVYDAPLVFFCQNNQWAISEPTE
RQSRLPLYQRARGYGFPGIRVDGNDVLACLAVTRWALEECRHGNGPVLIEAFTYRMDAHT
TTDDPTRYRLSEELEVWKHKDPIERVRVHLARNGFADQEWFDQIQSEADAFAADLREFCF
NMPEPPPERVFANVYAEPSPVLDAQRDEYLSYLAGFVEAGER
NT seq
1209 nt
NT seq
+upstream
nt +downstream
nt
atgccgtcccccgaacagtggacgcacccggagcccggcgaaggaccggccgcacaggcc
gcccaaccatcgcgggagcaggtgatcgccggtttgcgaaacacggacgcgggtggcgct
gaggtgactcagctgctcacccccgaaggcgagcgaatcgcttcgccgcagttcgaccgc
tacatctccgacgtcgacccggaagcgctgcgcgggctctaccgcgacatggtgctggtc
cgccgggccgaccgggaagccaacgccatgcagcgccagggccagctcggcatctgggtc
ccgctgctgggccaggaggccgcgcaggtcggctccggccgcgcgctcaagccgcaggac
atggccttcccgagctaccgggaacacggcgtggcctacacccgcggtgtcgacttcaag
gaactgctgggcatcttccggtgcaccgaccacggtggctgggacttccaggcccacggc
ttccacccgtacaccatcgtgatcggcaaccaggtcctcaacgccgccggctacgcgatg
ggccagaagttcgagggcaaggtcggtgacgacgacggcgaagcgaccatcgtctacttc
ggtgacggcgccacctcgcagggcgacgtgcacgagggcttcgtgtgggccgcggtgtac
gacgcgccgctggtgttcttctgccagaacaaccagtgggcgatctccgagccgaccgag
cgccagtcccggctcccgctgtaccagcgcgcccgcggctacggcttccccggcatccgc
gtcgacggcaacgacgtgctggcctgcctcgcggtgacccgctgggcgctcgaggagtgc
cgccacggcaacggcccggtgctgatcgaggcgttcacctaccggatggacgcgcacacc
accaccgacgatccgacccgctaccggctctccgaggagctggaggtgtggaagcacaag
gacccgatcgagcgcgtgcgggtgcacctggcgcgcaacgggttcgccgaccaggagtgg
ttcgaccagatccagtccgaggccgacgccttcgccgcggacctgcgcgagttctgcttc
aacatgccggaaccgccgccggaacgcgtgttcgcgaacgtctacgccgaaccgtcgccg
gtgctcgacgcccagcgcgacgagtacctgtcctacctggccggtttcgtggaagcgggt
gagcgctga
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