Amycolatopsis thermalba: L1857_04980
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Entry
L1857_04980 CDS
T08681
Symbol
menD
Name
(GenBank) 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
KO
K02551
2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase [EC:
2.2.1.9
]
Organism
athm
Amycolatopsis thermalba
Pathway
athm00130
Ubiquinone and other terpenoid-quinone biosynthesis
athm01100
Metabolic pathways
athm01110
Biosynthesis of secondary metabolites
athm01240
Biosynthesis of cofactors
Brite
KEGG Orthology (KO) [BR:
athm00001
]
09100 Metabolism
09108 Metabolism of cofactors and vitamins
00130 Ubiquinone and other terpenoid-quinone biosynthesis
L1857_04980 (menD)
Enzymes [BR:
athm01000
]
2. Transferases
2.2 Transferring aldehyde or ketonic groups
2.2.1 Transketolases and transaldolases
2.2.1.9 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylic-acid synthase
L1857_04980 (menD)
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Motif
Pfam:
TPP_enzyme_N
TPP_enzyme_C
TPP_enzyme_M_2
Motif
Other DBs
NCBI-ProteinID:
UQS22221
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Position
982690..984354
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AA seq
554 aa
AA seq
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MNPSTAQAKVIVDELVRNTVSHVVLCPGSRNAPLSLALHAAAAAGRLQLHVRIDERGAGF
LALGIAARTGRPVAVVCTSGTAAANFHPAVLEADRAGVPLIVLTADRPPELRAAGANQVI
EQQRLYGGAVRYFDELAVAERRGGQNAYWRSQICRAWNAAYGEWRCGPVHLNVPFREPLV
PDGDDEWYESLEGRPGGERWTELPDFGALPSFVVPSARCGLVIACDSGVRAAGEWGEQHG
WPVISETGGLGLLGSSAISSGVWLLGAEEFIRRHKPEQVLCLGRPTVFRQIQQLLSDSDV
EVLLVRPDSDWPAPAHNVRQVGQWFDSPTKPADPDWLAAWQRADALANEAVGRALRREQW
PSGLRLASELVDALPPDALLVVGSSNPARDVALAGRMRPDILVHRNRGVAGIDGTVSTAI
GAASVHRGHSYALLGDLTFLHDVNGLLAGPADTRPDLTIVVLNDDGGGIFSLLEQGAPEH
RDAFEHVFGTPHGADLSALCAGFGIPHVRAGTIEEFREALRPAPGLRVVEVQVDRTRHRD
LHARIRGAVSTALA
NT seq
1665 nt
NT seq
+upstream
nt +downstream
nt
gtgaatccgtcgaccgcgcaggccaaggtcatcgtggacgaactcgtccgcaacaccgtc
tcccacgtggtgctctgcccgggctcgcgcaacgcgccgctgtcgctggcgctgcacgcc
gcggccgccgcgggacgcctccagctgcacgtccgcatcgacgagcggggcgccggtttc
ctcgcgctcggcatcgcggcgcgcaccgggcgcccggtcgccgtggtgtgcaccagcggc
accgcggcggcgaacttccaccccgcggtcctggaggccgaccgggccggggtgccgctg
atcgtgctgaccgccgaccgcccgccggagctgcgggccgcgggcgcgaaccaggtcatc
gagcagcagcggctctacggcggcgcggtccgctacttcgacgagctggccgtcgccgag
cggcgcggtggccagaacgcgtactggcgcagccagatctgccgggcctggaacgcggcc
tacggcgagtggcgctgcggcccggtgcacctgaacgtcccgttccgcgagccgctggtg
cccgacggcgacgacgagtggtacgagtcgctggagggccgccccggcggggagcgctgg
accgagctgccggacttcggcgcgttgccgtcgttcgtggtgccctcggcccggtgcggc
ctggtcatcgcgtgcgacagcggggtgcgggccgccggggagtggggtgagcagcacggc
tggccggtgatctcggagaccggcggcctcgggctgctcgggtcgtcggcgatctcgtcc
ggcgtgtggctgctcggcgcggaggagttcatccgacggcacaagccggagcaggtgctg
tgcctcggcaggccgacggtgttccggcagatccagcagctgctgtcggactccgacgtc
gaggtgctgctggtgcgcccggactcggactggcccgcgcccgcgcacaacgtgcggcag
gtcgggcagtggttcgactcgccgaccaagccggccgatccggactggctggccgcgtgg
cagcgggccgatgcgctggcgaacgaggccgtcggccgggcgttgcggcgcgagcagtgg
ccgagcgggctgcggctggcgtccgagctggtggacgccctgccgccggacgcgctgctg
gtggtcggctcgtcgaacccggcgcgggacgtggcgctggccggccggatgcggccggac
atcctggtgcaccgcaaccgcggggtggcgggcatcgacggcacggtgtcgacggcgatc
ggcgcggcgtcggtgcaccgcgggcactcctacgcgctgctcggcgacctgacgttcctg
cacgacgtcaacggcctgctggccggtccggcggacacccggccggacctgacgatcgtg
gtcctcaacgacgacggcggcgggatcttctcgctgctggaacagggcgcgcccgagcac
cgggacgcgttcgagcacgtgttcggcaccccgcacggcgcggacctgtcggcgctgtgc
gcggggttcggcatcccgcacgtgcgcgccggcacgatcgaggagttccgcgaggccctg
cgcccggcgcccggcctgcgggtggtcgaggtgcaggtggaccgcacccgccaccgcgac
ttgcacgcgcgcatccgcggcgcggtgtcgacagcgctggcctga
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