Amycolatopsis thermalba: L1857_06265
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Entry
L1857_06265 CDS
T08681
Name
(GenBank) GMC family oxidoreductase
KO
K03333
cholesterol oxidase [EC:
1.1.3.6
]
Organism
athm
Amycolatopsis thermalba
Pathway
athm00984
Steroid degradation
athm01120
Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:
athm00001
]
09100 Metabolism
09111 Xenobiotics biodegradation and metabolism
00984 Steroid degradation
L1857_06265
Enzymes [BR:
athm01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.3 With oxygen as acceptor
1.1.3.6 cholesterol oxidase
L1857_06265
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Gene cluster
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Motif
Pfam:
DAO
GMC_oxred_N
GMC_oxred_C
FAD_binding_2
Pyr_redox_2
NAD_binding_8
Pyr_redox
FAD_oxidored
FAD_binding_3
GIDA
HI0933_like
Thi4
Fer4_10
Fer4_9
Motif
Other DBs
NCBI-ProteinID:
UQS22451
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Position
1268933..1270666
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AA seq
577 aa
AA seq
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MTSRNSNAADYDVIVVGSGFGGSVAALRLTEKGYRVAVVEAGRRFADDEFAKTSWDLKRY
LWAPALGCFGIQRIHLLRDVMILAGAGVGGGSLVYANTLYRPLKPFYQDKQWAHITDWES
ELAPYYDQASRMLGVVTNPTVTPSDEVIQKVAADMGVADSYHPTPVGVFFDKPGQRVPDP
YFGGAGPERTGCTECGSCMTGCRVGAKNTLVKNYLYLAEQGGAQVIPLTTVTAVRPRGDG
SFEVDVRKTGTRSKRFRTTLTAGRVVLAAGTWGTQRLLHEMRDQGVLPRLSPRLGELTRT
NSEAIIGAGRPTVDPERDFSKGVAITSSFHPDESTHIEPVRYGKGSNAMSLLQTIATDGS
VPTPRWLQAVRFLARHPVQSAKLLNGYRWSERTVILLVMQSLDNSITTYTRRGLFGRRKY
TSKQGHGEPNPTFIPAGHQANELTAKHIDGTAGGTWGEVFDIPLTAHFIGGAPIGTSPED
GVIDPYHRVFGYPGLSIVDGTAITANLGVNPSLTITAQAERAFSFWPNKGEADQRPDQSK
GYRRIKPVAPKNPAVPADAPAALRLPLVSTGRSRRTR
NT seq
1734 nt
NT seq
+upstream
nt +downstream
nt
gtgacctcgcgtaacagcaatgcggctgactatgacgtcatcgtggtcggatcggggttc
ggcggcagcgtcgccgcgctccggctgaccgagaagggctaccgggtggccgtcgtggag
gcgggccgccggttcgccgacgacgagttcgccaagacgtcctgggacctcaagcgctac
ctgtgggcgccggcgctgggctgcttcggcatccagcggatccacctgctccgcgacgtg
atgatcctggccggcgccggggtcggcggcgggtcgctggtgtacgccaacacgctgtac
cggccgctcaagccgttctaccaggacaagcagtgggcgcacatcaccgactgggagtcc
gagctggcgccgtactacgaccaggcgagccggatgctcggggtggtcacgaaccccacg
gtgacgccgtcggacgaggtcatccagaaggtcgccgccgacatgggcgtggccgacagc
taccacccgacgccggtcggggtgttcttcgacaagccggggcagcgggtgcccgacccg
tacttcggcggggccgggccggagcggacgggctgcaccgagtgcggctcgtgcatgacc
ggctgccgggtcggcgcgaagaacacgctggtcaagaactacctgtacctcgccgaacag
ggcggcgcgcaggtcatcccgctgaccacggtcaccgctgtccgcccgcgcggggacggc
tcgttcgaggtcgacgtgcgcaagaccggcaccaggtcgaagcggttccgcaccacgctc
accgccgggcgggtcgtgctcgccgcgggcacctggggcacgcagcggctgctgcacgag
atgcgcgaccagggcgtgctgccccggctgtcgccgcggctgggcgagctgacccgcacc
aactccgaggccatcatcggcgccggccgcccgaccgtcgacccggagcgcgacttcagc
aagggcgtggcgatcacgtcgtcgttccaccccgacgagtccacccacatcgagccggtg
cgctacggcaagggcagcaacgcgatgagcctgctgcagacgatcgccaccgacggttcg
gtgccgacgccgcgctggctgcaggcggtgcggttcctggccaggcacccggtgcagagc
gcgaagctgctcaacgggtaccggtggagcgagcggaccgtgatcctgctggtgatgcag
agcctggacaactcgatcaccacctacaccaggcgcggcctgttcgggcggcgcaagtac
acgtcgaagcagggccacggcgagccgaacccgacgttcatcccggccggccaccaggcg
aacgagctgaccgccaagcacatcgacggcaccgcgggcggcacctggggcgaggtcttc
gacatcccgctcaccgcgcacttcatcggcggcgcgccgatcggcaccagccccgaggac
ggggtgatcgacccgtaccaccgggtgttcggctaccccggactgtccatcgtggacggt
accgcgatcaccgcgaacctcggcgtgaacccgtcgctgaccatcaccgcgcaggccgag
cgcgcgttctcgttctggcccaacaagggcgaggcggaccagcggccggaccagtcgaag
ggctaccggcggatcaagccggtcgcgccgaagaacccggcggtcccggccgacgcgccg
gccgccctccgactgccgctggtgtctacaggtcgatcccggcgaacacggtga
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