Amycolatopsis thermalba: L1857_22625
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Entry
L1857_22625 CDS
T08681
Name
(GenBank) alpha-ketoacid dehydrogenase subunit beta
KO
K00167
2-oxoisovalerate dehydrogenase E1 component subunit beta [EC:
1.2.4.4
]
Organism
athm
Amycolatopsis thermalba
Pathway
athm00280
Valine, leucine and isoleucine degradation
athm00640
Propanoate metabolism
athm00785
Lipoic acid metabolism
athm01100
Metabolic pathways
athm01110
Biosynthesis of secondary metabolites
athm01210
2-Oxocarboxylic acid metabolism
Module
athm_M00036
Leucine degradation, leucine => acetoacetate + acetyl-CoA
Brite
KEGG Orthology (KO) [BR:
athm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00640 Propanoate metabolism
L1857_22625
09105 Amino acid metabolism
00280 Valine, leucine and isoleucine degradation
L1857_22625
09108 Metabolism of cofactors and vitamins
00785 Lipoic acid metabolism
L1857_22625
Enzymes [BR:
athm01000
]
1. Oxidoreductases
1.2 Acting on the aldehyde or oxo group of donors
1.2.4 With a disulfide as acceptor
1.2.4.4 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring)
L1857_22625
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Motif
Pfam:
Transket_pyr
Transketolase_C
PFOR_II
Motif
Other DBs
NCBI-ProteinID:
UQS25399
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Position
4665880..4666866
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AA seq
328 aa
AA seq
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MTATKVTMAQAINTALRDAMTEDPSVVVFGEDVGPLGGVFRVTDGLTGAFGEQRCFDTPL
AESGIAGMAIGMAMNGFRPVVEMQFDAFAYPAFEQITSHLAKMGNRTRGRVRLPVVVRVP
YAGGIGGVEHHCDSSEAYYAHTPGLTVVAPATNEDAYGLLREAIASPDPVIFLEPKRHYF
TREEVDFARAVPPIGRAVVRRPGRDATLIAYGPSVPVALAAAGQAATEGRDLAVVDVRSI
VPFDDETVTRAVAATGRAVVVAEAPGFASVAAEIAARVSEQCFPYLEAPVRRVTGFDIPY
PPPKLEHHHLPSVNRILDAVDELNWDAA
NT seq
987 nt
NT seq
+upstream
nt +downstream
nt
atgaccgcgaccaaggtgacgatggcgcaggccatcaacaccgcactgcgcgacgcgatg
accgaggacccctcggtcgtcgtgttcggcgaggacgtcggcccgctcggcggcgtcttc
cgggtgaccgacgggctcaccggcgccttcggcgagcagcgctgtttcgacacgccactg
gccgagtcgggcatcgccggcatggcgatcgggatggccatgaacggcttccgcccggtg
gtcgagatgcagttcgacgccttcgcctacccggcgttcgaacagatcaccagccacctg
gcgaagatgggcaaccgcacccgcggccgcgtccggctgccggtggtcgtgcgggtcccc
tacgccgggggcatcggcggggtcgagcaccactgcgactcctccgaggcctactacgcg
cacaccccgggcctcaccgtcgtcgcgcccgccacgaacgaagacgcctacggcctgctc
cgcgaagccatcgcgagcccggacccggtgatcttcctcgaaccgaagaggcactacttc
acccgcgaggaggtcgacttcgcgcgggcggttcccccgatcggccgcgcggtcgtgcgc
cgcccgggccgggacgccaccctcatcgcctacggcccgtccgtcccggtcgcgctcgcc
gccgccggccaggccgccaccgaaggccgcgacctcgccgtggtcgacgtgcgctcgatc
gtgccgttcgacgacgagacggtcaccagggccgtcgccgccaccggccgggcggtcgtc
gtcgccgaggcgccgggcttcgcctccgtcgcggccgaaatcgccgcgcgggtgagcgag
cagtgcttcccctacctggaggcgccggtccgccgcgtcaccggcttcgacatcccttac
ccgccaccgaaactcgaacaccaccacctgccctcggtgaaccggatcctggacgccgtc
gacgagctgaactgggacgccgcatga
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