Anaerolinea thermophila: ANT_03330
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Entry
ANT_03330 CDS
T01410
Name
(GenBank) 2-isopropylmalate synthase/homocitrate synthase family prtoein
KO
K01649
2-isopropylmalate synthase [EC:
2.3.3.13
]
Organism
atm
Anaerolinea thermophila
Pathway
atm00290
Valine, leucine and isoleucine biosynthesis
atm00620
Pyruvate metabolism
atm01100
Metabolic pathways
atm01110
Biosynthesis of secondary metabolites
atm01210
2-Oxocarboxylic acid metabolism
atm01230
Biosynthesis of amino acids
Module
atm_M00432
Leucine biosynthesis, 2-oxoisovalerate => 2-oxoisocaproate
Brite
KEGG Orthology (KO) [BR:
atm00001
]
09100 Metabolism
09101 Carbohydrate metabolism
00620 Pyruvate metabolism
ANT_03330
09105 Amino acid metabolism
00290 Valine, leucine and isoleucine biosynthesis
ANT_03330
Enzymes [BR:
atm01000
]
2. Transferases
2.3 Acyltransferases
2.3.3 Acyl groups converted into alkyl groups on transfer
2.3.3.13 2-isopropylmalate synthase
ANT_03330
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Paralog
Gene cluster
GFIT
Motif
Pfam:
HMGL-like
LeuA_dimer
HCS_D2
Motif
Other DBs
NCBI-ProteinID:
BAJ62367
UniProt:
E8N032
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All DBs
Position
359122..360723
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AA seq
533 aa
AA seq
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MRCAMKIEVYDTTLRDGTQRTDISLSVNDKLNIARRLDMLGVDFIEGGWPGSNPKDAEFF
ARAAEMEWKHAQIAAFGATCAVEKTPEQDENILALLESRAPVCTVVGKSSVLHVHEVLRT
TLENNLRIIEQSLAYLKAQGRRVIYDAEHFFDGYKEDPEYALQTLAAALRGGAETLVLCD
TNGGSLPWEVGEIVRAVRVRFPHARLGIHAHNDGECAVANSLAAVREGCVQVQGTINGYG
ERCGNANLCSILPDLELKMGYTCLPQGHLAQLTDLSHYVAEVANLAPDEHLAYVGKAAFA
HKGGIHVAAMRRTPRSYQHIDPALVGNTSQVVVSELSGRGNLLSKAEEYGIPLEEGVDVS
GVLREVKALEAQGFSFEAADASVMLMLLRQKPDYQPPFTLVDFTAGVEHRQGRGIFAEAT
VKVRVGEQVIHTAAEGNGPVAALDAALRKALLPYYPAISAFHLSDYKVRILDGPNGTSAT
TRVLIETRNGHRSWGTVGASTNIIEASWRALADSIEYGIWVAEHQVEPAPALP
NT seq
1602 nt
NT seq
+upstream
nt +downstream
nt
atgaggtgtgccatgaaaatcgaagtgtacgacactaccctgcgcgatggaacgcaacga
accgacatctctttatcggtgaatgacaaactgaacattgcccgccgtctggacatgctg
ggcgtggatttcatcgagggcggctggcccggctccaaccccaaggatgccgaattcttt
gcccgtgcggcagagatggagtggaaacacgcgcaaattgccgcctttggcgcgacctgt
gcggtggagaaaacccccgaacaggatgagaacatcctcgccttgctggagtcgcgcgcg
ccggtgtgtacggtggtgggtaaatcttcggtattgcacgtccatgaggtcctgcgcacc
acgctggagaacaatctgcgcatcatcgagcagtcgctggcgtacctgaaggcgcaggga
cggcgggtgatttacgatgccgaacacttcttcgatggctacaaagaagaccctgaatat
gccctgcagacgctggcggcggcattgcgcggcggcgccgagacgctggtgctgtgcgat
accaatggcggcagtctgccctgggaggtgggtgaaattgtgcgcgcggtgcgggtgcgt
ttcccacacgccaggctgggcatccatgctcacaacgacggcgagtgtgcggtggcaaac
tcgctggcggcggtgcgcgagggctgtgtgcaggtgcaggggacgataaacggctacggg
gagcgctgtggcaatgccaatctgtgttccatcctgcccgatctggaactgaagatgggc
tatacctgcctgccgcaggggcatctggcgcagttgaccgacctttcccactacgtggcg
gaggttgccaacctggcgccggacgagcatctggcatatgtggggaaagccgcctttgcc
cacaaggggggcatccatgtggctgccatgcggcgcacgccacgctcgtaccagcacatt
gacccggcgctcgtgggcaatacctcgcaggtggtggtttcagaactctccgggcggggt
aacctgctcagcaaagctgaggaatacggcatccctctggaagaaggcgtggatgtgagt
ggcgttctgcgcgaggtcaaggcgctggaagcgcagggcttttcctttgaagccgccgat
gcctcggtgatgttgatgctgttgcgtcagaagcccgattaccagccgccgtttacgctg
gtagatttcaccgccggggtggaacaccgtcaggggcggggcatctttgccgaagccacg
gttaaggtgcgtgtaggcgagcaggtcatccacaccgccgctgagggcaatggtcctgtc
gccgcgctggatgctgccctgcgcaaagccctcttgccttattaccctgccatctccgct
ttccacctctcggattacaaggtgcgcatcctggacggtcccaacggcacttctgccacc
acccgcgtgttgattgagacgcgcaatgggcatcgttcctggggcacggtaggcgccagc
accaatatcatcgaagcctcgtggcgcgcgctggcagattccattgaatacggcatctgg
gttgccgaacatcaggtggagcctgcgccggcacttccataa
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