Anaerolinea thermophila: ANT_23340
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Entry
ANT_23340 CDS
T01410
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
atm
Anaerolinea thermophila
Pathway
atm00300
Lysine biosynthesis
atm00550
Peptidoglycan biosynthesis
atm01100
Metabolic pathways
atm01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
atm00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
ANT_23340 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
ANT_23340 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
ANT_23340 (murF)
Enzymes [BR:
atm01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
ANT_23340 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
MoCF_biosynth
MazE-like
Motif
Other DBs
NCBI-ProteinID:
BAJ64360
UniProt:
E8MYM4
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Position
2577432..2578865
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AA seq
477 aa
AA seq
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MLTLTDVLEALTGKHIDMQKPLTFSEAAIDSRQVIPGSLFVALPGVRTDGHQFVGAAFQN
GAILALVEKDLPQDFPTLDLRAVSPETPLAFPASWIPGQPLCLRVNNTLEALQQLARYWR
RRLNIRVIGITGSVGKSTTKELIAEVLSQRYRTLKNPGNLNNEIGLPLTLLRLGKGHERA
VLEMGFYVPGEIALLCDIAQPQVGVITNIGTVHAERAGSQEAIARGKSELVQALPVGGYA
ILNHDDPWVRWMADKTQAQILYYGLTPEAHLWADEIETMGLEGIRFRLHYRRESFSVRVP
LIGHHSVQTALRATAVGIVEGLTWGEIIHGLQRSPTQLRLVAVRSSSGALILDDTYNASP
ESTLASLQILHEMKGRRIAVLGDMLELGPYEQSGHEKVGVRAAEVADVLVAVGELSKIIA
RAAREAGMKPEKIFWVPDTSQAIEVLRPLLKEGDVVLIKGSHGLRMDRIVSALEVVG
NT seq
1434 nt
NT seq
+upstream
nt +downstream
nt
gtgttgaccctgacggacgttctggaagccctgaccggcaagcatatagacatgcaaaag
cccctcaccttcagtgaggcggcaattgattcccgtcaggtcatcccggggtctttgttt
gtggcgcttccgggagtgcgcaccgatgggcatcaatttgtcggtgcagcattccagaac
ggtgcaatcctggcgctggtggagaaagacctccctcaagactttcctacccttgatttg
agagccgtttctccggaaacccccctggccttcccggcttcgtggattcccggacaaccg
ctttgcctgcgcgtgaacaacacgcttgaagcactgcaacaactggcacgttactggcgc
agacgcctgaatatccgggtcatcggcattaccggcagtgtgggaaaatccacaaccaag
gaattgattgccgaggtgctttctcagcgctaccgcactttgaaaaatccgggcaacctg
aataatgaaatcgggttaccgctgaccctgttgcggcttggcaaaggccatgaacgtgcc
gtacttgaaatgggtttctacgtgcctggagaaattgccctgctgtgcgacattgcccaa
cctcaggtcggggtcattaccaatatcggcaccgtgcatgccgaacgagcaggctcccaa
gaagccattgcgcgaggaaaatcagaactggtgcaagccctgcctgtgggtggatacgcc
atcctgaaccatgacgacccatgggtgcgctggatggcagataaaacccaagcccagatc
ctgtattacgggttgacacccgaagcgcatctgtgggcagatgaaatcgaaaccatgggc
ttggaaggcattcgcttccgcctgcattaccgacgggagtctttctcggtgcgggtgcct
ttgattggccatcactcggtacaaactgcattgcgggctaccgcggtaggaatcgtggaa
gggttaacctggggagaaattatccacgggcttcaacgctctcccacgcaactgcgcctg
gtagccgtgcgctcttccagcggtgcactgattctggatgacacttataacgcttctccg
gagtcgaccctggcatctctgcaaatcctccacgagatgaagggaagacgcattgccgtg
ttgggagacatgctggaactgggtccatatgaacagagcgggcatgagaaagtcggtgtg
cgtgccgccgaagttgccgatgtgttggtggctgtaggggaattgagtaaaatcattgct
cgagccgcccgggaagccggaatgaaacccgagaagattttctgggttcccgatacttct
caggcaattgaagtgctcagacccctactcaaggaaggagatgttgtcttgattaaaggc
tcgcacggtttacgcatggaccgcatcgtcagcgcgctggaggtggtaggatga
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