Actinomarinicola tropica: GH723_08355
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Entry
GH723_08355 CDS
T06914
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
atq
Actinomarinicola tropica
Pathway
atq00300
Lysine biosynthesis
atq00550
Peptidoglycan biosynthesis
atq01100
Metabolic pathways
atq01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
atq00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GH723_08355 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GH723_08355 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GH723_08355 (murF)
Enzymes [BR:
atq01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GH723_08355 (murF)
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GFIT
Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Motif
Other DBs
NCBI-ProteinID:
QGG95110
UniProt:
A0A5Q2RML0
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Position
1701451..1702812
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AA seq
453 aa
AA seq
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MGRRPDPRRPVRFTADDIAQRTGGEVIGDPSVEVVGATQDSRTVAPGQLFVPLVAGRDGH
EFIPVAVERGATAYLASDRARVVDGATAIAVEDTQVALVDLGRAARHRLDGAVVGITGSV
GKTTVKDLARGVLGAAAPTHASAASFNNEIGVPLTLLGTPDGTRHVVVEMGARGIGHIAE
LCAIAHPTVGVVTRVAMAHSELFGTIEDIARGKGEMVEQLPADGTAVLNAGDQRVAAMAD
RTSARVLTFGLGVGDVRATTMDVAADLRLRVLLETPWGAIEVEPAARGPHNAENAAAAAA
IGLGVGMDLADVATGLAAAEMSPLRMAITTSRSGVTILDDSYNANPTSMRAALDALAHLP
AERRVAVVGLMAELGPESDAEHEAVAALAEELGVELIAVDCPEYRADAHGGRAVHDIDGA
LDLLDGAGTGTAVLAKGSRVAGLDRLVAALADR
NT seq
1362 nt
NT seq
+upstream
nt +downstream
nt
atgggacgccgtcccgacccgaggagacccgtgcggttcaccgcagacgacatcgcgcag
cgcaccggcggcgaggtcatcggcgacccctcggtcgaggtcgtcggcgccacccaggac
tcgcggacggtcgctcccggccagctcttcgtgccgctcgtcgccggccgtgacgggcac
gagttcatccccgtggccgtcgagcggggggcgacggcgtacctcgcctcggaccgggcc
cgggtggtcgacggggccaccgcgatcgccgtcgaggacacccaggtggccctggtcgac
ctcggtcgcgccgcgcgccaccggctcgacggcgccgtcgtgggcatcaccggatcggtc
ggcaagacgacggtgaaggacctcgcccgcggggtcctcggggccgcggcccccacccac
gccagcgccgcgagcttcaacaacgagatcggcgtgcccctcacgctcctcggcacgccc
gacggcacccggcacgtcgtcgtcgagatgggcgctcgcggcatcggccacatcgccgag
ctgtgcgccatcgcccaccccaccgtcggtgtcgtcacccgggtggcgatggcccacagc
gagctcttcggcaccatcgaggacatcgctcgcggcaagggcgagatggttgagcagctg
cccgccgacggcacggcggtcctgaacgccggcgaccagcgggtggcagcgatggccgac
cgcacctcggcccgggtgctcaccttcgggctcggcgtgggcgacgtgcgggcgacgacg
atggacgtcgcggccgacctgcgcctgcgcgtgctgctcgagaccccgtggggcgccatc
gaggtggagcctgcggcgcgtggcccgcacaacgccgagaacgcggccgctgcggcggcc
atcggcctcggggtgggcatggacctcgccgacgtggccacggggctggccgcggcggag
atgtcgccgctgcggatggccatcacgacctcgcgctcgggcgtgacgatcctcgacgac
tcctacaacgccaaccccacctcgatgcgggcggcgctcgacgcgctcgcgcacctcccg
gccgagcgccgcgtcgcggtcgtggggctgatggccgagctcgggcccgagtccgacgcc
gagcacgaggccgtcgccgcgctggccgaggagctcggcgtcgagctgatcgccgtcgac
tgccccgagtaccgcgccgatgcgcacggtggtcgcgccgtgcacgacatcgacggggcg
ctcgacctgctcgacggggccgggacgggcaccgccgtgctcgcgaagggttctcgcgtc
gccggcctcgatcgcctcgtggcggcgctcgccgaccgctga
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