Acidithiobacillus thiooxidans: GCD22_00302
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Entry
GCD22_00302 CDS
T06281
Symbol
murF
Name
(GenBank) UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase
KO
K01929
UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase [EC:
6.3.2.10
]
Organism
atx
Acidithiobacillus thiooxidans
Pathway
atx00300
Lysine biosynthesis
atx00550
Peptidoglycan biosynthesis
atx01100
Metabolic pathways
atx01502
Vancomycin resistance
Brite
KEGG Orthology (KO) [BR:
atx00001
]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
GCD22_00302 (murF)
09107 Glycan biosynthesis and metabolism
00550 Peptidoglycan biosynthesis
GCD22_00302 (murF)
09160 Human Diseases
09175 Drug resistance: antimicrobial
01502 Vancomycin resistance
GCD22_00302 (murF)
Enzymes [BR:
atx01000
]
6. Ligases
6.3 Forming carbon-nitrogen bonds
6.3.2 Acid-D-amino-acid ligases (peptide synthases)
6.3.2.10 UDP-N-acetylmuramoyl-tripeptide---D-alanyl-D-alanine ligase
GCD22_00302 (murF)
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Motif
Pfam:
Mur_ligase_M
Mur_ligase_C
Mur_ligase
Motif
Other DBs
NCBI-ProteinID:
QFX94834
UniProt:
A0A5P9XMH8
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All DBs
Position
complement(279687..281039)
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AA seq
450 aa
AA seq
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MMRYSLNEIARITGGQLLPGSQGKDEIHGIATDSRQPMIGKLFVALTGEHFDGNDFVPAA
LAQGAAAVLSNRQVDAPGVVVKDTLQSLQSLAQHWRQRFNIPVLAVTGSCGKTTVKEVLT
AILAESGPVLATQGNQNNHIGVPLTLARLGVEHRYAVLEMGMNHPGELTLLSALAKPTLA
LINNAGPAHLAGLGTVAAVAAAKGEILSGLDNRGISILNGDDQFADFWAEKAPGEVWRFS
LNNLPVRVRGHWQDRSGSSGQLDVRAPQGEFTLEVPLPGKHNGANVLAAVTAALALDISI
PQIQRAVAALEAIPGRLQWRNGRGGCRVLDDTYNANPASLEAALRVLAAQSGQRILILGD
MGELGPDTVVYHRQAGILAHQLGIDAVYGLGQLAAKAAEAFAAGTEHFMELPPLIDALQP
HLNPETVVLVKGSRAAHMERVVQALVAGDA
NT seq
1353 nt
NT seq
+upstream
nt +downstream
nt
atgatgcgctactccctcaacgaaatagcccgcatcaccggtggccagcttctgcctggc
agccagggaaaggacgaaatacacggcattgccacggacagtcgccaacccatgattggc
aaactgtttgttgcactgaccggagaacactttgatgggaacgactttgttccggcagct
ttagcccagggcgcggccgccgtactcagcaaccgtcaggtggatgcgcccggagtagtg
gtcaaggacactttgcaaagcttgcaaagcctggcacagcattggcgccagcgtttcaac
ataccggtgctggcggttaccggctcctgtggcaaaaccacggtcaaggaagtcctgaca
gccatccttgccgaaagcggccccgtactggccactcaaggcaatcagaacaaccatatt
ggcgtgcccctgaccctggcaagactgggggtggaacatcgctatgcggtactggaaatg
ggcatgaaccatcccggcgaactcaccctgctcagcgcactggccaaaccaacgttggcc
ctcatcaacaatgccggccccgcccatctggcgggactcggaactgtggctgccgtcgcg
gcggccaagggcgaaattctctcgggactggacaatcgtggcatcagcattttgaatggt
gacgatcaatttgccgacttctgggcagaaaaagctccgggcgaagtgtggcgcttcagt
ctgaacaacctcccggtacgcgtccgtggacattggcaggatcgttcaggaagcagcggc
caactggatgtacgcgccccccagggcgaattcaccctcgaagtcccgctcccgggaaaa
cataatggtgccaatgtcctggctgccgtcaccgccgcactggccctggatatcagcatc
cctcagattcagcgtgctgtggccgcgttggaagccatccccgggcgcttgcaatggcgc
aacggaaggggcggctgccgggttctggatgacacctacaacgccaatccagcttcatta
gaggccgcattacgtgttcttgccgcccaatccggccagcgtattctcatactcggagat
atgggtgaactgggtcccgatacggtagtttatcaccggcaggcaggaattctggcccat
cagctgggcattgatgcggtttacggactgggacaactggctgccaaagccgccgaagcg
tttgcagccggtacagagcattttatggaactgccccccctgattgatgctctgcagccc
catctcaatccggaaacggtagtgctggtaaaaggttccagagctgcacacatggaacgt
gtcgttcaggcactcgtggctggagacgcctga
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